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| | Psychedelic Information Theory : Neurotransmitters & Neuromodulators: The Psychedelic Connection, by James Kent (Site not responding. Last check: 2007-11-06) |
 | | In effect, neuromodulators are there to fine tune the neural response to incoming stimulus (slow it down, speed it up, shut it off, etc.) and to keep the various disparate brain circuits all functioning smoothly and in unison. |
 | | And though there is some feedback response from the higher brain which affects the flow of endogenous amines coming from the brainstem, these neuromodulators mostly tend to produce a bottom-up effect, which means they are switched automatically and unconsciously as directed by the brainstem. |
 | | Through the diffuse projection of these neuromodulators, the impulses from the primitive brainstem can have a global effect on the entire brain all at once, thus causing the entire brain organ to speed up, slow down, amplify, or filter signals as it sees fit. |
| www.tripzine.com /pit.asp?id=pit08 (5785 words) |
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