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	Kids.Net.Au - Encyclopedia > Neuromyotonia
		Neuromyotonia is spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin.
		Neuromyotonia is considered to be one of these with accumulating evidence for autoimmune origin over the last few years.
		Some neuromyotonia cases do not only improve after plasma exchange but they may also have antibodies in their serum[?] samples against voltage-gated potassium channels.
	www.kids.net.au /encyclopedia-wiki/ne/Neuromyotonia (241 words)

	CIGNA - Neuromyotonia
		Neuromyotonia is a rare neuromuscular disorder characterized by abnormal nerve impulses from the peripheral nerves.
		Neuromyotonia is characterized by involuntary continuous muscle fiber activity (fasciculations) that cause stiffness and delayed relaxation in the affected muscles.
		Neuromyotonia may be treated with anticonvulsant drugs such as phenytoin, or with carbamazepine, which may stop the abnormal impulses and prevent the symptoms from reoccurring.
	www.cigna.com /healthinfo/nord758.html (1643 words)

	Neuromyotonia
		Neuromyotonia is spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin.
		Neuromyotonia is considered to be one of these with accumulating evidence for autoimmune origin over the last few years.
		Some neuromyotonia cases do not only improve after plasma exchange but they may also have antibodies in their serum[?] samples against voltage-gated potassium channels.
	www.ebroadcast.com.au /lookup/encyclopedia/ne/Neuromyotonia.html (216 words)

	Neuromyotonia - WrongDiagnosis.com
		Neuromyotonia (medical condition): A condition which is characterized by myotonia caused by electrical activity of the peripheral nerve.
		Neuromyotonia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Neuromyotonia, or a subtype of Neuromyotonia, affects less than 200,000 people in the US population.
	www.wrongdiagnosis.com /medical/neuromyotonia.htm (208 words)

	Neuromyotonia (Site not responding. Last check: )
		Neuromyotonia je spontánní svalnatá aktivita vyplývat z opakovaného motorového jednotkového akčního potentials z okrajovém původu.
		Neuromyotonia je považován za jeden z těchto s hromadícím se důkazem pro autoimunní původ přes trvat nemnoho roků.
		Velmi malý podíl případů se neuromyotonia může vyvinout centrální nervózní systémové nálezy v jejich klinickém kursu, vyvolání poruchy volalo Morvan syndrom a oni mohou také mít protilátky proti kanálům draslíku v jejich vzorkách séra.
	wikipedia.infostar.cz /n/ne/neuromyotonia.html (217 words)

	CIN2001: "ACUTE RENAL FAILURE DUE TO HERBAL MEDICINE INTOXICATION IN ACQUIRED NEUROMYOTONIA"
		Neuromyotonia (NMT) is an uncommon syndrome of spontaneously occurring muscle activity of peripheral nerve origin, which can be triggered by voluntary or induced muscle contraction in which hyperexcitability of peripheral nerves leads to incapacitating muscle twitching, cramps, and weakness.
		Neuromyotonia (NMT) is a rare disorder of unknown cause described by Issacs1 in which hyper excitability of peripheral motor nerves resulting in continuous muscle fiber activity which leads to incapacitating muscle twitching, cramps, and weakness.
		Neuromyotonia also occurs at increased frequency with certain tumors that are well recognized to produce autoantibody-mediated, paraneoplastic disorders of the peripheral nervous system3.
	www.uninet.edu /cin2001-old/paper/ibanez/foyaca.html (1169 words)

	NEUROMYOTONIA (Site not responding. Last check: )
		Neuromyotonia은 자연스러운 근활성도 이어 주변 원천의 반복적인 운동 단위 활동 전위에서 유래한.
		Neuromyotonia은 자기 면역 원천을 위해 축적 기록에 이들의 하나개 지난 몇년 동안 것 여긴다.
		neuromyotonia에 상자의 아주 작은 비율은Morvan증후군이라고 부르는 무질서의 원인이 되는 그들의 임상 과정안에 중앙 신경 조직 사실 인정을 개발하골지도 그들의 혈청 견본안에 칼륨 수로향하여 또한 항체가 있을지도 모른다.
	www.faktoko.com /wiki/ko/ne/Neuromyotonia.htm (150 words)

	neuromyotonia (Site not responding. Last check: )
		Neuromyotonia is considered to be one of these with accumulating...
		Neuromyotonia is a syndrome characterised by motor unit hyperactivity leading to muscle cramps...
		Neuromyotonia is a rare neuromuscular disorder characterized by abnormal nerve...
	uchasnegi.com /neuromyotonia (303 words)

	Hereditary neuromyotonia: a mouse model associated with deficiency or increased gene dosage of the PMP22 gene -- TOYKA ...
		Hereditary neuromyotonia: a mouse model associated with deficiency or increased gene dosage of the PMP22 gene -- TOYKA et al.
		Hereditary neuromyotonia: a mouse model associated with deficiency or increased gene dosage of the PMP22 gene
		Neuromyotonia is characterised by increased muscle stiffness caused by hyperactivity of motor units.
	jnnp.bmjjournals.com /cgi/content/full/63/6/812 (764 words)

	Neuromyotonia: Clinical profile of twenty cases from northwest India Panagariya Ashok, Kumar Hrishikesh, Mathew Vivek, ...
		Neuromyotonia, with all its synonyms is an enigmatic entity, in part because of its remarkable clinical pleomorphism, uncertain natural history and anecdotal response to various therapies.
		The term 'Neuromyotonia' found its place in the early papers of Zondeck[1] and Brown,[2] but it was Isaacs[3] who described the condition in detail.
		We are documenting here 20 cases of neuromyotonia with classical electromyographic picture and their follow-up with response to various therapies.
	www.neurologyindia.com /article.asp?issn=0028-3886;year=2006;volume=54;issue=4;spage=382;epage=386;aulast=Panagariya (3479 words)

	User:Erdem Tüzün
		In neurology, his research interests are autoimmune diseases of peripheral nerve and neuromuscular junction (particularly myasthenia gravis and neuromyotonia) and new techniques in electromyography / nerve conduction studies.
		He has studied in Oxford University as an academic visitor to perform a research project about the involvement of antibodies to central nervous system antigens in central nervous system disorders.
		His major contributions are demonstration of antibodies against voltage-gated potassium channels in some patients with limbic encephalitis, identification of the autoimmune etiology of neuromyotonia and demonstration of autoantibodies against thalamic structures as a causal factor for Morvan's syndrome and application of F tacheodispersion method in diabetes mellitus patients with subclinical neuropathy for early diagnosis.
	www.ebroadcast.com.au /lookup/encyclopedia/er/ErdemTuzun.html (141 words)

	CNI Review Medical Journal - Online Library - Colorado Neurological Institute
		Neuromyotonia (Isaacs' syndrome) appears to be due to antibody-induced blockade of potassium channels along peripheral axons.
		Generalized myokymia and neuromyotonia may be seen in the absence of traditional disease of peripheral nerves or motor neurons as in Isaacs' syndrome.
		Such generalized acquired neuromyotonia has been shown to be associated with autoantibodies directed against potassium channels in peripheral motor axons.
	www.thecni.org /reviews/13-2-p02-england.htm (2533 words)

	Paraneoplastic Neurological syndromes: Professional area neuromyotonia
		Generalized peripheral nerve hyperexcitability (PNH; neuromyotonia) is often a non-paraneoplastic condition, but many cases are associated with autoimmunity or with other autoimmune disorders (see Table).
		Autoantibodies detected to expressed potassium channels are implicated in neuromyotonia.
		Neuromyotonia, myoclonus, sensory neuropathy and cerebellar symptoms in a patient with antibodies to neuronal nucleoproteins (anti-Hu-antibodies).Clin Neurol Neurosurg 1999; 101:207-209.
	www.pnseuronet.org /professionals/nmt.htm (501 words)

	Neuromyotonia Treatment and Symptoms
		Isaac's syndrome (also known as neuromyotonia, Isaac's-Merten's syndrome, continuous muscle fiber activity syndrome, and quantal squander syndrome) is a rare neuromuscular disorder caused by continuous signaling of the end regions of peripheral nerve fibers that activate muscle fibers (motor neurons).
		Neuromyotonia is spontaneous muscular activity resulting from repetitive mo...
		Isaac's syndrome (also known as neuromyotonia, Isaac's-Merten's syndrome, continuous muscle fiber activity syndrome, and quantal squander syndrome) is a rare neuromuscular disorder caused...
	goldbamboo.com /topic-t3395.html (350 words)

	Baylor Neurology Case of the Month
		The EMG confirmed the absence of fasciculations and showed the presence of doublets, widespread irregular grouped motor unit discharges, and complex repetitive discharges with mixed widespread myotonic discharges which was consistent also with a diagnosis of Isaacs' syndrome or neuromyotonia.
		The patient's father also had a history of cramps, but the patient probably did not have the familial form of the disease because of the good response he had to treatment with plasma exchange, as outlined later.
		Also the anti-GAD antibodies seen in Stiffman's syndrome are not seen in neuromyotonia.
	www.bcm.edu /neurol/challeng/pat2/summary.html (1287 words)

	LetsFind Search Results for neuromyotonia (Site not responding. Last check: )
		Polio and Post-Polio News: Neuromyotonia: Clinical profile of twenty cases from northwest India.
		Ocular neuromyotonia is a rare motility disorder occurring after tumor...
		IngentaConnect Neuromyotonia and myasthenia gravis in the absence of thymoma
	www.letsfind.co.uk /transform.php?Keywords=neuromyotonia (159 words)

	Neuromyotonia Encyclopedia Information @ Karr.net (Karr Network) (Site not responding. Last check: )
		Neuromyotonia, also known as Isaacs' Syndrome, is spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin.
		As a result of muscular hyperactivity patients may present with muscle cramps, myotonia-like symptoms, excessive sweating, myokymia and fasciculations.
		Anticonvulsants, including phenytoin and carbamazepine, usually provide significant relief from the stiffness, muscle spasms, and pain associated with neuromyotonia.
	209.197.127.220 /encyclopedia/Neuromyotonia (537 words)

	-- Data Supplement - December 2004 Video Report -- British Journal of Ophthalmology
		Conversely, individuals with ocular motor neuromyotonia are usually asymptomatic and have normal eye movements between attacks.4 Most cases are diagnosed in adults.
		Our video illustrates the typical eye movements of neuromyotonia, an uncommon treatable entity that must be considered when evaluating a patient with variable diplopia and strabismus, and that can easily be missed if its distinctive features are not recognized.
		Ocular neuromyotonia in a patient with cavernous sinus thrombosis secondary to mucormycosis.
	bjo.bmjjournals.com /cgi/content/full/88/12/DC1/1 (864 words)

	Neuromyotonia in mice with hereditary myelinopathies. (Site not responding. Last check: )
		The purpose of this study was to further characterize neuromyotonia in mice with deletions and point mutations of myelin protein genes.
		This indicates that spontaneous motor unit activity may underlie neuromyotonia, which is occasionally observed in Charcot-Marie-Tooth disease.
		Clinical observation showed irregular stretching of the hindlimbs, tremor and generalized myokymia in mice with targeted deletions of the genes encoding myelin protein zero (P0-/-) or peripheral myelin protein 22 (Pmp22-/-), and Trembler mice, which carry a point mutation of Pmp22.
	www.ihop-net.org /UniPub/iHOP/gp/8489986.html (185 words)

	Reference.com/Encyclopedia/Neuromyotonia
		Neuromyotonia, also known as Isaacs' Syndrome, is spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin.
		As a result of muscular hyperactivity patients may present with muscle cramps, myotonia-like symptoms, excessive sweating, myokymia and fasciculations.
		Anticonvulsants, including phenytoin and carbamazepine, usually provide significant relief from the stiffness, muscle spasms, and pain associated with neuromyotonia.
	www.reference.com /browse/wiki/Neuromyotonia (319 words)

	Neuromyotonia - Health Topics - Medical Encyclopedia - MSN Health & Fitness (Site not responding. Last check: )
		It is possible that the main title of the report Neuromyotonia is not the name you expected.
		Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
		Neuromyotonia is a rare neuromuscular disorder characterized by abnormal nerve impulses from the peripheral nerves.
	health.msn.com /encyclopedia/healthtopics/articlepage.aspx?cp-documentid=100073184 (394 words)

	Fakultní nemocnice Brno - Kliniky a oddìlení - Nemocnice Bohunice (Site not responding. Last check: )
		The case of a 71-year-old female patient suffering from acquired paraneoplastic neuromyotonia with an unusual electrophysiological pattern of neuromyotonic discharges (NMD) evoked exclusively by voluntary contraction or electrical stimulation is reported.
		We present here a case of an acquired paraneoplastic neuromyotonia associated with thymoma and clinically manifested myotonia-like muscle stiffness and an unusual electrophysiological pattern of neuromyotonic discharges that were evoked voluntarily or with electrical stimulation but were absent spontaneously and were not elicited by needle displacement.
		Though it is not an easy task to define the discharges in hyperirritable neuromuscular disorders, actual definitions of neuromyotonic discharges emphasising their spontaneous occurrence or initiation by needle movement should, however, be reconsidered and modified.
	www.fnbrno.cz /article.asp?nDepartmentID=28&nArticleID=458&nLanguageID=1 (1778 words)

	MORVAN’S SYNDROME
		Neuromyotonia (spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin) is considered to be one of these with accumulating evidence for autoimmune origin over the last few years.
		A very small proportion of cases with neuromyotonia may develop CNS findings during their clinical course, causing a disorder called Morvan’s syndrome (Ms).
		Ms is a rare disease characterised by neuromyotonia, the dysfunction of autonomic nervous system and CNS and endocrine disturbances (16).
	www.med.ege.edu.tr /~norolbil/2001/NBD14801.html (2732 words)

	Ocular neuromyotonia secondary to a cavernous sinus meningioma. (Site not responding. Last check: )
		Ocular neuromyotonia secondary to a cavernous sinus meningioma.
		This article was last updated on Friday, 30th June 2006 at 1:30 am and is filed in the Clonazepam section.
		Bookmark Ocular neuromyotonia secondary to a cavernous sinus meningioma.
	counsellingresource.com /medications-research/2006/06/30/ocular-neuromyotonia-secondary-to-a-cavernous-sinus-meningioma (186 words)

	NewsRx - The Worlds Largest Source of News (Site not responding. Last check: )
		"Neuromyotonia is a rare condition of spontaneous and continuous muscle fibre activity of peripheral nerve origin.
		This review highlights the classical clinical, electrophysiological and immunological features of this disorder from what is currently known in the literature to date, and also from the author's own patients' studies.
		Neuromyotonia is best classified as a moderately severe disorder of peripheral nerve hyperexcitability, with electromyographic features of spontaneous, continuous, irregularly occurring doublet, or multiplet single motor unit (or partial motor unit) discharges, firing at a high intraburst frequency (30-300Hz).
	www.newsrx.com /print.php?articleID=398251 (296 words)

	Issacs' Syndrome Successfully Treated With Phenytoin At Low Doses
		We report two patients with Isaacs' syndrome (acquired neuromyotonia) who responded remarkably well clinical and electromyografically to low doses of phenytoin orally.
		Patients presented with associated common diseases in the former Transkei (South Africa) such as neurocysticercosis, shistosomiasis, tuberculosis and HIV seropositive and we have hypothesized about neuro-immunologic mechanism, and peripheral nerve membrane disorders in these patients and the phenytoin response.
		Acquired neuromyotonia: a new autoantibody-mediated neuronal potassium channelopathy.
	www.ispub.com /ostia/index.php?xmlFilePath=journals/ijn/vol1n2/issacs.xml (777 words)

	Polio and Post-Polio News: Neuromyotonia: Clinical profile of twenty cases from northwest India.
		Performance of acute flaccid paralysis (AFP) surveillance and incidence of poliomyelitis, 2006 (data received in WHO headquarters as of 7 November 2006).
		Neuromyotonia: Clinical profile of twenty cases from northwest India.
		CONCLUSIONS: Neuromyotonia is a heterogeneous condition and can present in varied ways including diffuse nonspecific pain.
	mt.lincolnshirepostpolio.org.uk /archives/pandpp-news/002026.html (402 words)

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