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Topic: Niacin

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	Linus Pauling Institute at Oregon State University
		Niacin deficiency was found to decrease bone marrow NAD and poly-ADP-ribose levels and increase the risk of chemically induced leukemia (12), and niacin supplementation decreased the risk of ultraviolet light-induced skin cancers in mice (13).
		In the case of niacin, research on biochemical and cellular aspects of DNA repair have stimulated an interest in the relationship between niacin intake and cancer risk in human populations (16).
		An increase in niacin intake of 6.2 mg was associated with about a 40% decrease in cases of cancers of the mouth and throat, while a 5.2 mg increase in niacin intake was associated with a similar decrease in cases of cancer of the esophagus.
	lpi.oregonstate.edu /infocenter/vitamins/niacin (3487 words)

	Niacin - Wikipedia, the free encyclopedia
		Niacin, when taken in large doses, increases the level of High density lipoprotein (HDL)or "good" cholesterol in blood, and is sometimes prescribed for patients with low HDL, and at high risk of heart attack.
		Niacin (but not niacinamide) is also used in the treatment of hyperlipidemia because it reduces Very low density lipoprotein (VLDL), a precursor of Low density lipoprotein (LDL) or "bad" cholesterol, secretion from the liver, and inhibits cholesterol synthesis.
		Niacin in itself is not toxic, but the chemicals converted by niacin are toxic to the skin and liver in overdose, and high doses of niacin should only be reached with gradual increase.
	en.wikipedia.org /wiki/Niacin (670 words)

	Niacin (Nicotinic Acid)
		Niacin, via its metabolites, is involved in a wide range of biological processes, including the production of energy, the synthesis of fatty acids, cholesterol and steroids, signal transduction, the regulation of gene expression and the maintenance of genomic integrity.
		Niacin and substances that are convertible to niacin are found naturally in meat (especially red meat), poultry, fish, legumes and yeast.
		The well-known disorder of niacin deficiency is pellagra.
	www.pdrhealth.com /drug_info/nmdrugprofiles/nutsupdrugs/nia_0184.shtml (4551 words)

	Niacin - Supplements
		Niacin is a water-soluble B vitamin — and the common name for two very different compounds: nicotinic acid and niacinamide.
		Because niacin is involved in the proper functioning of more than 200 metabolic enzymes, it plays a role in a wide range of bodily processes, including synthesis of hormones and blood cells and the release of energy from fats, carbohydrates and proteins.
		Niacin is cheap — so its effectiveness in reducing cholesterol levels may be an inexpensive solution to reducing a known risk factor for cardiovascular disease.
	www.supplementwatch.com /supatoz/supplement.asp?supplementId=335 (1218 words)

	Nutrition Fact Sheet: Niacin (vitamin B3), Nutrition, Feinberg School of Medicine
		Niacin is an essential vitamin that supports energy metabolism and reactions involving biosynthesis and degradation as part of the pyridine nucleotide coenzymes, nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP).
		Niacin can be obtained from consumption of food sources or from biosynthesis with the amino acid tryptophan as a precursor.
		Pellagra is the clinical manifestation of advanced niacin deficiency that is characterized by dermatitis, dementia, and diarrhea.
	www.feinberg.northwestern.edu /nutrition/factsheets/vitamin-b3.html (439 words)

	Niacin Powder (Vitamin B3), 300 Grams Powder (Site not responding. Last check: 2007-11-06)
		Niacin is the only B vitamin that can be synthesized in the body from the amino acid tryptophan.
		High doses may produce a pronounced niacin flush, characterized by tingling, reddening, and itching of the skin produced by the release of histamine.
		Pure niacin is acidic and may require a buffering agent to be co-ingested if its acidity is unacceptable.
	www.lef.org /newshop/items/item00094.html (233 words)

	Niacin Info (Site not responding. Last check: 2007-11-06)
		Niacin is an especially good choice if the goal is to raise the HDL (good cholesterol).
		Further, high doses of Niacin can cause liver toxicity, and these levels of niacin should only be taken under the supervision of your doctor who will follow your liver function tests.
		This form of niacin lowers serum cholesterol, although it is not as potent as regular niacin, but it appears to have far fewer side effects, and the dose can be increased more quickly.
	www.formyhealth.com /niacin.htm (638 words)

	PROVET HEALTHCARE INFORMATION - Niacin (Site not responding. Last check: 2007-11-06)
		Niacin is an essential vitamin found in many foods of plant and animal origin.
		Niacin can also be synthesised from the amino acid tryptophan via nicotinic acid in dogs and other species- but not in cats, mink or fish.
		Reports of niacin deficiency are rare in cats but, as they can not synthesise niacin from tryptophan, they are likely to be very susceptible to a dietary deficiency.
	www.provet.co.uk /health/diseases/niacin.htm (215 words)

	Niacin (Vitamin B3, Nicotinic acid), Niacinamide - MayoClinic.com (Site not responding. Last check: 2007-11-06)
		Niacin (vitamin B3) and niacinamide are FDA approved for the treatment of niacin deficiency.
		Niacin decreases blood levels of cholesterol and lipoprotein (a), which may reduce the risk of atherosclerosis ("hardening" of the arteries).
		Use of niacin supplementation during pregnancy or breastfeeding is not recommended due to lack of sufficient research of safety and effectiveness.
	www.mayoclinic.com /health/niacin/NS_patient-niacin (1829 words)

	NIACIN Pellagra dementia
		Niacin (nicotinic acid or nicotinamide) is essential in the form of the coenzymes nicotinamide adenine dinucleotide (NAD) and NAD phosphate (NADP) in which the nicotinamide moiety acts as an electron acceptor or hydrogen donor in many biological redox reactions.
		Niacin and NAD are biosynthesized from dietary tryptophan via the kynurenine pathway and quinolinic acid.
		Excess niacin is excreted in the urine primarily as N
	www.eagle-min.com /faq/faq100.htm (480 words)

	niacin
		Niacin, one of the most stable of the B vitamins, is a common name for two compounds: nicotinic acid and nicotinamide.
		The nicotinic acid form of niacin prompts the liver to produce less of a protein that carries triglycerides and LDL cholesterol.
		Niacin+ also contains 100 mg of a chelated form of vitamin C. Recent research has demonstrated the importance of vitamin C to cardiovascular health.
	www.healthstores.com /physiologics/cholesterol/niacin.htm (445 words)

	Vitamin B3 (Niacin) (via CobWeb/3.1 planet03.csc.ncsu.edu) (Site not responding. Last check: 2007-11-06)
		Niacin deficiency also results in burning in the mouth and a swollen, bright red tongue In the United States alcoholism is the prime cause of Vitamin B3 deficiency.
		High doses of niacin produce the side effects of flushing of the skin (which can be reduced by taking aspirin 30 minutes before the niacin), stomach upset (which usually subsides in a few weeks), headache, dizziness, blurred vision, and liver damage.
		Niacin should not be taken at the same time as the antibiotic tetracycline because it interferes with the absorption and effectiveness of this medication.
	www.umm.edu.cob-web.org:8888 /altmed/ConsSupplements/VitaminB3Niacincs.html (2291 words)

	Niacin patient advice including side effects
		Although the niacin in Niacin is one of the B-complex vitamins, Niacin isn't taken to prevent deficiencies.
		Niacin is prescribed, along with a low-fat, low cholesterol diet, to reduce blood cholesterol levels, combat clogged arteries, and lower the chance of repeated heart attacks.
		Niacin is also used to reduce very high levels of the blood fats known as triglycerides, a condition that can cause painful inflammation of the pancreas.
	www.drugs.com /pdr/NIACIN.html (1378 words)

	Niacin - Drugs & Vitamins - Drug Library - DrugDigest
		Niacin supplements are occasionally prescribed to treat pellagra, a serious but rare niacin-deficiency disorder.
		Large doses of nicotinic acid, a form of niacin, are prescribed to help decrease the amount of fatty substances in the blood, known as cholesterol and triglycerides.
		If you are taking niacin for a medical condition (such as to lower cholesterol levels), your prescriber or health care professional may have you start with low doses, with slow increases in the dose to help your body become used to the medicine.
	www.drugdigest.org /DD/DVH/Uses/0,3915,484\|Niacin,00.html (815 words)

	Niacin and Flushing
		Niacin is a B vitamin which can lower LDL cholesterol (the bad kind) and raise HDL cholesterol (the good kind).
		Niacin can also worsen gout and raise the blood sugar in diabetics.
		Niacin is available over-the-counter in regular and time-release forms.
	www.health.mcw.edu /article/901646925.html (239 words)

	Niacin
		B vitamins, niacin assists enzymes, the catalysts that help spark chemical reactions.
		niacin, your doctor will begin with a much lower dose and increase it gradually over a period of weeks to help minimize flushing, says Dr. Milner.
		Niacin can help people with Raynaud’s disease for reasons that are related to the way it causes blood vessels to expand.
	www.bodyandfitness.com /Information/Health/Research/niacin.htm (874 words)

	Niacin (nicotinic acid): Vitamins: Merck Manual Home Edition (Site not responding. Last check: 2007-11-06)
		Niacin is essential for the metabolism of carbohydrates, fats, and many other substances in the body.
		Furthermore, the niacin in maize cannot be absorbed in the intestine unless the maize is treated with alkali (as it is when tortillas are prepared).
		Niacin (but not nicotinamide) in high doses may be prescribed to lower high fat (lipid) levels in the blood.
	www.merck.com /mmhe/sec12/ch154/ch154h.html (406 words)

	Herbal Descriptions - Niacin - Nicotinic Acid (Site not responding. Last check: 2007-11-06)
		Niacin is water-soluble and is not sensitive to heat, acids, or alkalis.
		Niacin improves circulation and reduces the cholesterol level in the blood; maintains the nervous system; helps metabolize protein, sugar and fat; reduces high blood pressure; increases energy through proper utilization of food; prevents pellagra; and helps maintain a healthy skin, tongue and digestive system.
		A deficiency of niacin may result in pellagra, gastrointestinal disturbance, nervousness, headaches, fatigue, mental depression, vague aches and pains, irritability, loss of appetite, insomnia, skin disorders, muscular weakness, indigestion, bad breath, and/or canker sores.
	www.viable-herbal.com /herbdesc3/1niacin.htm (607 words)

	Niacin
		The daily niacin dosage was started at 375 mg taken nightly and slowly increased, to a maximum of 3,000 mg per day, at four-week intervals for a total of 25 weeks.
		Niacin, for example, causes flushing, and fibrates are associated with gastrointestinal side effects.
		Niacin use significantly increased HDL-C by 29% and 29% and decreased triglycerides by 23% and 28% and low-density lipoprotein cholesterol (LDL-C) by 8% and 9%...
	qualitycounts.com /fpniacin.html (2699 words)

	Vitamin B3, Inositol Hexaniacinate, Niacin, Niacinamide, Nicotinamide, Nicotinic Acid
		Niacin, in amounts as low as 50–100 mg, may cause flushing, headache, and stomachache in some people.
		In a group of people being treated alternatively with niacin and inositol hexaniacinate for skin problems, niacin supplementation (50–100 mg per day) was associated with numerous side effects, including skin flushing, nausea, vomiting and agitation.
		Contrasting effects of unmodified and time-release forms of niacin on lipoproteins in hyperlipidemic subjects: clues to mechanism of action of niacin.
	www.truestarhealth.com /Notes/2926008.html (848 words)

	Niacin (nicotinic acid, vitamin B3, Niacor, Niaspan, Slo-Niacin) to Cholesterol Lowering Drug Information by ...
		Niacin also is used to reduce cholesterol and triglyceride levels in the blood.
		It is not clear how niacin causes its effects on cholesterol and triglyceride levels, but it may be by reducing the production of proteins that transport cholesterol and triglycerides in the blood.
		Niacin should be discontinued if liver tests are greater than three times the upper limit of normal, are persistently elevated, or accompanied by nausea, vomiting or weakness.
	www.medicinenet.com /niacin/article.htm (759 words)

	Magnacarta Net
		And Billy maintains that even though Niacin's daunting writing is the domain of John and himself, the Dennis Chambers vibe is an integral part of the trio-riffic whole.
		Keyboardist John Novello is, in essence, the guitarist and lead vocalist of Niacin even if he accomplishes the entire ball of wax on his coterie of B-3 vocabularies.
		Niacin's B-3 sound harkens back to a great history within the rock tradition, something the band has front-and-center celebrated and revived.
	www.magnacarta.net /bands_profile.asp?Band_ID=20 (962 words)

	MedlinePlus Medical Encyclopedia: Niacin
		Niacin is a water-soluble vitamin necessary for many aspects of health, growth, and reproduction.
		Niacin assists in the functioning of the digestive system, skin, and nerves.
		Niacin (also known as vitamin B-3) is found in dairy products, poultry, fish, lean meats, nuts, and eggs.
	www.nlm.nih.gov /medlineplus/ency/article/002409.htm (388 words)

	What Is The Niacin Flush?
		If you take niacin in an amount significantly larger than you have been taking in the past few days you are likely to experience a "flush," or a reddening of the skin and an itchy feeling.
		Niacin is a particularly important nutrient for improving the health of the heart and for improving blood circulation.
		When you take niacin, begin with 100mg/day, for the first time you are probably going to have that "niacin flush" and feel itchy and have red skin.
	www.oralchelation.com /faq/answers24.htm (4102 words)

	NIACIN Side Effects, NIACIN Drug Information, NIACIN Dosage
		NIACIN may cause flushing and a feeling of warmth about the face and neck within the first two hours of taking a dose.
		Niacin (nicotinic acid) is used to prevent and treat niacin deficiency.
		If niacin is used for treating a lipid (high cholesterol or triglyceride) problem, then it should be used only when clearly needed during pregnancy.
	www.pharmacyhealth.net /d/niacin-2691.htm (728 words)

	Niacin (B3)
		Find out how niacin could be the answer to a number of your deficiency problems.
		Niacin (vitamin B3) is a member of the B-complex vitamin family.
		Niacin is also useful for balancing blood sugar levels, which helps in the prevention of diabetes.Niacin can also be used to stimulate a healthy nervous system, and eases symptoms of depression, anxiety and insomnia.
	www.lifescript.com /channels/well_being/Vitamins/niacin.asp (362 words)

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