
	Where results make sense

Topic: Nonseminoma

In the News (Sat 26 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Early-stage Testis Cancer
		For clinical stage I nonseminoma, equivalent short-term survival rates are obtained with either nerve-sparing retroperitoneal lymph node dissection (RPLND), surveillance, or two courses of BEP (bleomycin, etoposide, and platinum) chemotherapy.
		The pathology of seminoma appears to be more indolent than nonseminoma and the median time to recurrence in surveillance series of seminoma ranges between 10 to 16 months as opposed to the vast majority of patients with nonseminoma managed by surveillance recurring within the first year of follow-up.
		In clinical stage I nonseminoma, despite the fact that CT scans show no evidence of any metastatic disease and marker levels are either normal or falling normally based on half lives, around 30% of patients have occult metastatic disease [7].
	www.treatment-options.com /article.cfm?PubID=ON02-5-2-01&Type=Article (3753 words)

	Extragonadal Germ Cell Tumors
		Early surgery for nonseminoma is seldom useful, and patients may be treated in a clinical trial.
		Nonseminomas that occur in the chest are more frequent in patients who have Klinefelter's syndrome.
		Patients with nonseminoma that occurs near the kidneys generally respond well to treatment, depending on the size of the tumor.
	www.marystolfacancerfoundation.com /ExtragonadalGermCellTumors.html (564 words)

	Which treatment should I have for my stage I nonseminoma testicular cancer?
		While seminomas respond well to radiation therapy, nonseminomas tend to be very resistant to radiation therapy.
		Nonseminoma cells are also more likely to travel through the bloodstream to the lungs, liver, bones, and brain.
		Stage I cancers are those that are believed to be confined to the testes, though in some cases they may have spread to the lymph nodes of the lower back (retroperitoneum) but are undetectable.
	www.peacehealth.org /kbase/dp/topic/zr1065/dp.htm (1898 words)

	[No title]
		Nonseminomas: These germ cell cancers tend to develop earlier in life than seminomas, usually occurring in men between their late teens and early 40s.
		The main types of nonseminomas are embryonal carcinoma, yolk sac carcinoma, choriocarcinoma, and teratoma.
		All nonseminoma germ cell cancers are treated the same way, so the exact type of nonseminoma is not that important, except that they do have different patterns of spread.
	www.cancer.org /docroot/CRI/content/CRI_2_4_1X_What_is_testicular_cancer_41.asp?sitearea= (1511 words)

	Testicular & Dietary Issues-Full Text
		There were 82 men diagnosed with nonseminoma tumors, 46 men diagnosed with pure seminomas, and 32 men diagnosed with mixed germ cell tumors.
		The ethnic distribution of men with nonseminoma, seminoma, and mixed germ cell tumors was generally similar to that of controls.
		An inverse relation was observed for calcium and dietary fiber intake and nonseminoma cancer risk and no consistent trend was observed for milk, fruit, vegetable, or dark green and deep yellow fruit and vegetable consumption.
	www.annieappleseedproject.org /tesdietistex.html (2351 words)

	Testicular Cancer: Survival High with Early Treatment
		Nonseminomas are a group of cancers that sometimes occur in combination, including choriocarcinoma, embryonal carcinoma, and yolk sac tumors.
		Seminomas and nonseminomas differ in their tendency to spread, their patterns of spread, and response to radiation therapy.
		Though most nonseminomas are not diagnosed at an early stage, cases confined to the testicle may need no further treatment other than testicle removal.
	www.fda.gov /fdac/features/196_test.html (2178 words)

	Testicular Cancer
		For patients with low-stage disease, the cure rate approaches 100%.[1] Tumors which have a mixture of seminoma and nonseminoma components should be managed as nonseminoma.
		Nonseminoma includes embryonal carcinoma, teratoma, yolk sac carcinoma and choriocarcinoma, and various combinations of these cell types.
		However, for nonseminoma, the inaccuracy of both is a problem and frequently surgical staging is required.
	www.medhelp.org /lib/cancernet/101121.htm (5859 words)

	Cytogenetic analysis of a mature teratoma and a yolk sac tumor component of a late relapse of a disseminated testicular ... (Site not responding. Last check: 2007-10-16)
		Cytogenetic analysis of a mature teratoma and a yolk sac tumor component of a late relapse of a disseminated testicular nonseminoma.
		Cytogenetic analysis of a mature teratoma and a yolk sac tumor component of a late relapse of a disseminated testicular nonseminoma.The late relapse was composed of a mature teratoma and a yolk sac tumor component.
		We report on the cytogenetics of a primary testicular nonseminoma, a residual mature teratoma after remission-induction chemotherapy, and a late relapse after 9 years of follow-up, in one patient.
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/1839293.html (135 words)

	National Cancer Institute - Testicular Cancer Treatment
		Treatment of stage I testicular cancer depends on whether the cancer is a seminoma or a nonseminoma.
		Treatment of stage II testicular cancer depends on whether the cancer is a seminoma or a nonseminoma.
		Treatment of stage III testicular cancer depends on whether the cancer is a seminoma or a nonseminoma.
	www.nci.nih.gov /cancertopics/pdq/treatment/testicular/Patient/page5 (426 words)

	Testicular_Cancer_101 (Site not responding. Last check: 2007-10-16)
		Usually, seminomas are slow growing and tend to stay localized in the testicle for long periods.
		Nonseminomas are a group of cancers that often occur in combination with one another, including choriocarcinoma, embryonal carcinoma, immature teratoma, and yolk sac tumors.
		Nonseminomas arise from more mature, specialized germ cells and tend to be more aggressive than seminomas.
	michaelmerrill.com /Testicular_Cancer_101.html (483 words)

	[No title] (Site not responding. Last check: 2007-10-16)
		N Concordance 1 e patient should be treated as having a nonseminoma, even though the pathologic 2 r is broadly divided into seminoma and nonseminoma types for treatment planning 3 fetoprotein (AFP) should be treated as nonseminomas.
		Radiation therapy to the l 9 tage seminomas or RPLND for early-stage nonseminomas.
		Modifications in the surgi 10 in a proportion of the undifferentiated nonseminomas.
	www.ugr.es /~oncoterm/csdata/i_nsemin.txt (95 words)

	Testicular Cancer: Questions and Answers, Cancer Facts 6.34 (Site not responding. Last check: 2007-10-16)
		Nearly all testicular cancers are one of two general types: seminoma or nonseminoma.
		Based on the characteristics of the cells in the tumor, testicular cancers are classified as seminomas or nonseminomas.
		Nonseminomas tend to grow and spread more quickly; seminomas are more sensitive to radiation.
	cis.nci.nih.gov /fact/6_34.htm (2162 words)

	Endotext.com - Endocrinology Of Male Reproduction, Testicular Cancer Pathogenesis, Diagnosis and Endocrine Aspects
		Both seminoma and nonseminoma originate from CIS and are mainly observed in young adult men (2, 3, 13, 16).
		It is important to keep in mind that germ cell tumors rarely occur in pure histological forms, and for example HCG may be sometimes detected in serum of patients with seminoma due to the presence of some giant cells in a tumor mass.
		In general, however, high levels of AFP and HCG are associated with nonseminoma, whereas increased concentration of LDH in the absence of AFP and HCG suggests the presence of seminoma.
	www.endotext.org /male/male13/male13.htm (5779 words)

	Testicular Cancer: (Site not responding. Last check: 2007-10-16)
		Tumors which have a mixture of seminoma and nonseminoma components should be managed as nonseminoma.
		Testicular cancer is broadly divided into seminoma and nonseminoma for treatment planning because seminomatous types of testicular cancer are more sensitive to radiation therapy.
		Stage III nonseminoma is usually curable (70%) with standard chemotherapy.
	www.acor.org /cnet/62899.html (9434 words)

	Testicular Cancer
		Nonseminomas tend to grow and spread more quickly than seminomas.
		Nonseminomas are a group of cancers that include choriocarcinoma, embryonal carcinoma, teratoma, and yolk sac tumors.
		Nonseminomas are less sensitive to radiation, so men with this type of cancer usually do not undergo radiation.
	www.columbiahealthnet.org /Cancer_Directory/TesticularCancer.htm (2954 words)

	Extragonadal Germ Cell Tumors: (Site not responding. Last check: 2007-10-16)
		The latter group can be divided into seminoma and nonseminoma germ cell tumors, which include embryonal carcinomas, malignant teratomas, endodermal sinus tumors, choriocarcinomas, and mixed germ cell tumors.
		Craniospinal irradiation for intracranial germinomas (the intracranial counterpart of seminoma) is associated with relapse-free and overall survival rates of 90% to 95% at 5 years.
		The prognosis of retroperitoneal nonseminoma is reasonably good and, similar to the situation with nodal metastasis from a testicular primary, is related to tumor volume.
	www.acor.org /cnet/62939.html (1521 words)

	FUDA CANCER HOSPITAL GUANGZHOU (Site not responding. Last check: 2007-10-16)
		The two main types of testicular germ cell tumors are seminomas and nonseminomas.
		A testicular tumor that contains both seminoma and nonseminoma cells is treated as a nonseminoma.
		If cancer is found, the cell type (seminoma or nonseminoma) is determined in order to help plan treatment.
	www.orienttumor.com /english/t&t/Testicular_Cancer.htm (2779 words)

	Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation ...
		Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours.
		Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours.Testicular germ cell tumours (TGCTs) are histologically heterogeneous neoplasms with variable malignant potential.
		RASSF1A methylation was detected in four of 10 (40%) seminomas and 15 of 18 (83%) nonseminoma TGCT (NSTGCT) components (P=0.0346).
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/9867899.html (298 words)

	Testicular Cancer
		The surgeon does not cut through the scrotum and does not remove just a part of the testicle because, if the problem is cancer, cutting through the outer layer of the testicle might cause local spread of the disease.
		Nonseminomas are actually a group of cancers and comprise 60 percent of cases.
		For patients with nonseminoma, removing the nodes helps stop the spread of their disease.
	www.online-ambulance.com /articles/doc/3/grp/Men/art/Testicular.htm (1652 words)

	Baby boy is born from sperm frozen for 21 years UK
		(The suffix -oma means tumor.) Although some cancers contain both nonseminoma and seminoma cells, they are classified as nonseminomas because they grow and spread like nonseminomas.
		These tumors can be separated into 2 major categories, according to their differences in appearance under the microscope, different patterns of spread, and somewhat different responses to treatment.
		All nonseminoma germ cell cancers are treated the same way, so the exact type of nonseminoma is not that important.
	www.medicalnewstoday.com /newssearch.php?newsid=8667 (1791 words)

	UCCC - Cancer Information
		Malignant extragonadal germ cell tumors are divided into two types, nonseminoma and seminoma.
		A nonseminoma extragonadal germ cell tumor is in the intermediate prognosis group if:
		A nonseminoma extragonadal germ cell tumor is in the poor prognosis group if:
	www.uch.edu /CancerCenter/content/CancerInfo/Details.asp?Id=CDR0000271920&Type=Summary (2419 words)

	Cancer Spectrum: Physician Data Query - Treatment - Testicular Cancer
		About a quarter of patients with clinical stage I nonseminomatous testicular cancer will be upstaged to pathologic stage II with retroperitoneal lymph node dissection (RPLND), and about a quarter of clinical stage II patients will be downstaged to pathologic stage I with RPLND.
		Data from 380 patients treated from 1990 to 1994 on the same study protocol at 49 institutions in the European Organization for Research and Treatment of Cancer and the Medical Research Council were analyzed.
		Collette L, Sylvester RJ, Stenning SP, et al.: Impact of the treating institution on survival of patients with "poor-prognosis" metastatic nonseminoma.
	jncicancerspectrum.oxfordjournals.org /cgi/pdq/jncipdq;CDR0000062899 (10264 words)

	Treatment For Testicular Cancer - CancerNet Information For Professionals
		A number of prognostic classification schema are in use for metastatic nonseminomatous testicular cancer and for primary extragonadal nonseminomatous germ cell cancers treated with chemotherapy.
		It is important to note that even patients with widespread metastases at presentation, including those with brain metastases, may still be curable and should be treated with this intent.
		The majority of nonseminomas have more than 1 cell type, and the relative proportions of each cell type should be specified.
	www.vidyya.com /archives/1021_4.htm (9202 words)

	Germ Cell Tumors Extragonadal Germ Cell Tumors
		The latter group can be divided into seminoma and nonseminoma, which includes embryonal carcinoma, malignant teratoma, endodermal sinus tumor, choriocarcinoma, and mixed germ cell tumors.
		Patients with nonseminomatous extragonadal germ cell tumors who relapse after front-line chemotherapy generally have a poor prognosis with a poor response to salvage chemotherapy regimens, including autologous bone marrow transplantation, that have had success for recurrent testicular cancer.[12-14] Therefore, such patients are candidates for studies of new approaches.
		An international germ cell tumor prognostic classification has been developed based on a retrospective analysis of 5,202 patients with metastatic nonseminomatous and 660 patients with metastatic seminomatous germ cell tumors.[18] All patients received treatment with cisplatin- or carboplatin- containing therapy as their first chemotherapy course.
	www.medhelp.org /lib/cancernet/103773.htm (1184 words)

	[No title]
		Nearly 95% of all malignant testicular cancers are of the germ cell type that are divided into the seminoma and nonseminoma.
		Elevated AFP is produced by embryonal and yolk sac elements which are found only in nonseminomas.
		HCG however, is produced by both seminomas and nonseminomas.
	www.aremanda.com /step3/step3-test17.html (13448 words)

	Which treatment should I have for my stage I nonseminoma testicular cancer? (Site not responding. Last check: 2007-10-16)
		There are two main types of testicular cancer: seminoma and nonseminoma germ-cell tumors (also called NSGCTs).
		Both seminomas and nonseminomas are highly curable, especially if they are diagnosed and treated early.
		More than 90% of men who undergo RPLND are cured of testicular cancer and require no further treatment.
	www.healthnowny.com /kbase/dp/topic/zr1065/dp.htm (1898 words)

	Testicular Cancer: The Facts - Rhode Island Cancer Council, Inc. (Site not responding. Last check: 2007-10-16)
		The two main types of Germ Cell Carcinoma are seminoma and nonseminoma.
		Nonseminoma germ cell cancer normally occurs at an earlier age in life (early 20s on average) and grows more aggressively than seminoma.
		There are several classifications of nonseminoma germ cell cancer, but they all develop similarly and are treated alike.
	www.ricancercouncil.org /facts/testfacts.php (1320 words)

	Environmental Health Perspectives: Increased concentrations of polychlorinated biphenyls, hexachlorobenzene, and ... (Site not responding. Last check: 2007-10-16)
		OR (95% CI) for cases with testicular cancer, seminoma, and nonseminoma, respectively.
		OR and 95% CI for mothers of cases with testicular cancer, seminoma, and nonseminoma, respectively.
		The median concentration of the chemicals in the mothers of controls was used as cutoff value; numbers greater than the median (expressed in nanograms per gram lipid) are shown for cases and controls, and adjustment was made for age and BMI.
	www.findarticles.com /p/articles/mi_m0CYP/is_7_111/ai_105162044/pg_4 (332 words)

	Gene Expression Profiling in Seminoma and Nonseminoma -- Port et al. 23 (1): 58 -- Journal of Clinical Oncology
		Mean values from genes examined in five seminoma and six nonseminoma tumor biopsies that showed a significant (P <.05) differential expression (relative to normal tissue) were combined into 19 functional groups.
		Mean values from genes that showed a statistically significant difference in the expression of this gene in seminoma and the same gene in nonseminoma were combined into 15 functional groups.
		in nonseminoma (Fig 6), which, in most cases, was downregulated.
	www.jco.org /cgi/content/full/23/1/58 (4904 words)

	Gene Expression Profiling in Seminoma and Nonseminoma -- Port et al. 23 (1): 58 -- Journal of Clinical Oncology (Site not responding. Last check: 2007-10-16)
		Gene Expression Profiling in Seminoma and Nonseminoma -- Port et al.
		were usually upregulated in seminoma but downregulated in nonseminoma.
		A reverse pattern was found in 24.4% of such genes.
	jco.highwire.org /cgi/content/abstract/23/1/58 (358 words)

	Testicular Cancer - Urologychannel
		There are two main types: seminomas and nonseminomas.
		Spermatocytic seminomas grow slowly, usually do not spread to other parts of the body (metastasize), and are most common around age 65.
		Nonseminomas account for 60% of GCTs and develop in younger men (usually between 15 and 35).
	www.urologychannel.com /testicularcancer/index.shtml (479 words)

Try your search on: Qwika (all wikis)