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Topic: Notochord

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In the News (Tue 23 Apr 19)

  Notochord - Wikipedia, the free encyclopedia
It is composed of cells derived from the mesoderm and defining the primitive axis of the embryo.
The notochord is found on the ventral surface of the neural tube.
From the mesoderm surrounding the neural tube and notochord, the skull, vertebral column, and the membranes of the brain and medulla spinalis are developed.
en.wikipedia.org /wiki/Notochord   (519 words)

 Collagen II Is Essential for the Removal of the Notochord and the Formation of Intervertebral Discs -- Aszódi et ...
of the annulus fibrosus and notochordal sheath (Fig.
the notochord in wild-type mice, apoptosis, proliferation, and
and proliferation as a cause for the reorganization of the notochord.
www.jcb.org /cgi/content/full/143/5/1399   (7597 words)

 The relationships between notochord and floor plate in vertebrate development revisited -- Teillet et al. 95 (20): ...
Rostrally, in spite of the absence of notochord, the
Separation of the notochord from the neural tube results in the removal of the anterior part of the quail CNH, which is shown detached from the chicken lateral walls of the neural tube.
from the notochord is responsible for induction of the expression
www.pnas.org /cgi/content/full/95/20/11733   (4794 words)

 Chordata on Encyclopedia.com   (Site not responding. Last check: 2007-10-21)
In many fishes and in early fossil amphibians and reptiles the notochord persists in the adult and is enclosed by the vertebrae; in higher vertebrates, however, it disappears during embryonic development.
A few cartilaginous blocks around the notochord constitute the bare rudiments of a backbone; a cartilage framework supports the gill region, and there is a rudimentary cartilage braincase.
A high-affinity hemoglobin is expressed in the notochord of amphioxus, Branchiostoma californiense.
www.encyclopedia.com /html/C/Chordata.asp   (3348 words)

 DEVELOPMENTAL BIOLOGY: ON THE NOTOCHORD   (Site not responding. Last check: 2007-10-21)
In its "mature" state, the notochord is a rod of large cells constrained by a thick extracellular sheath and positioned between the developing spinal cord and gut.
Turgor pressure generated by notochord cells exerted against the sheath gives the notochord stiffness, imparting the mechanical properties required for one of its main functions as the central axial skeletal element of the developing embryo.
For the notochord enthusiast, the most astounding thing about this is that the majority of tissue derived from the graft is notochord, while the induced second axis is derived mostly from the host.
scienceweek.com /2004/sc041210-3.htm   (1913 words)

 Embryo: Notochord   (Site not responding. Last check: 2007-10-21)
The notochord of the 20-somite embryo, Carnegie No. 2053 is separated from the digestive epithelium in many areas, particularly caudally where the dorsal aorta have fused medially between the two tissues.
The notochordal plate and then the cord are intimately related to the neural tube until late in the stage when the primordial meninges form and separate the tissues at the cranial flexure and the area of RhD.
The notochord is no longer in contact with the endoderm except in the pharyngeal region and the caudal end of the embryo.
www.ana.ed.ac.uk /anatomy/database/humat/notes/embryo/notochor.htm   (553 words)

 Weill Cornell Physicians
The notochord is a distinctive feature of the chordate phylum and in vertebrates is the precursor of the backbone.
Today, the most primitive living animals with a notochord are the urochordates, which are marine invertebrate chordates.
We study the evolutionary origins of the notochord and its flanking tissues in a urochordate, the ascidian Ciona intestinalis.
www.med.cornell.edu /research/and2015   (316 words)

 Developmental Toxicity of the Dithiocarbamate Pesticide Sodium Metam in Zebrafish -- Haendel et al. 81 (2): 390 -- ...
The EC for notochord defects is 0.30 µM and the EC for reduced hatching is 0.28 µM. Three replicates of twenty embryos each were observed for each data point.
The EC for notochord defects is 0.35 µM and the EC for reduced hatching is 0.22 µM. Three replicates of twenty embryos each were observed for each data point.
The notochord is an axial structure common to the Chordata phylum.
toxsci.oxfordjournals.org /cgi/content/full/81/2/390   (4891 words)

 The notochord of hagfish Myxine glutinosa: visco-elastic properties and mechanical functions during steady swimming -- ...
E of the notochord are inversely proportional to the osmolarity
), the evolution of the notochord was not a prerequisite.
of hagfishes is not degenerate; the unsegmented notochord engaged
jeb.biologists.org /cgi/content/full/205/24/3819   (5785 words)

 An essential role of a FoxD gene in notochord induction in Ciona embryos -- Imai et al. 129 (14): 3441 -- Development
Blastomeres shown in orange are presumptive notochord cells, while those in yellow are primordial endodermal cells whose fates are restricted to the endoderm.
Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notochord in Ciona savignyi embryos.
FGF signals are involved in the differentiation of notochord cells and mesenchyme cells of the ascidian Halocynthia roretzi.
dev.biologists.org /cgi/content/full/129/14/3441   (6817 words)

 Notochord: Facts and details from Encyclopedia Topic   (Site not responding. Last check: 2007-10-21)
The notochord is a flexible rod-shaped body found in embryo embryo quick summary:
On the ventral aspect of the neural groove an axial thickening of the endoderm[For more info, click on this link] takes place; this thickening assumes the appearance of a furrow (the chordal furrow) the margins of which come into contact, EHandler: no quick summary.
A skull, or cranium, is a bony structure of vertebrates which serves as the general framework for a head....
www.absoluteastronomy.com /encyclopedia/n/no/notochord.htm   (658 words)

 Weill Cornell Research
Particular efforts are focused on investigating development and differentiation of the notochord.
During chordate embryogenesis, the notochord plays a crucial role in patterning the central nervous system, axial muscles, liver, pancreas, heart, gut and so on, and in establishing left-right asymmetry.
Animals with a notochord first appeared about 550 million years ago, at the time of the Cambrian explosion.
www.med.cornell.edu /research/adigregorio   (267 words)

 Tor70; notochord   (Site not responding. Last check: 2007-10-21)
In Xenopus the antibody is specific to notochord from the late neurula stage to about stage 28.
The notochord staining declines, as staining appears in the otic vesicle, cranial ganglia and a few proctodeal and stomodeal cells.
At stage 40, staining is absent from the notochord, but prominent in lateral line, proctodeum, stomodeum, and nasal pits.
www.xenbase.org /xmmr/Marker_pages/notochord/tor70noto.html   (426 words)

 Structure and function of the notochord: an essential organ for chordate development -- Stemple 132 (11): 2503 -- ...
(B) This is especially apparent in cross-section, where the area of the notochord is nearly equal to that of the neural tube.
Arrowheads indicate (A) chordamesoderm progenitor region of the shield, (B) the chordamesoderm and (C) the differentiated notochord.
Dorsal to the notochord is the floor plate, in the ventral-most part of the forming spinal cord.
dev.biologists.org /cgi/content/figsonly/132/11/2503   (616 words)

 Switching on the notochord -- Cunliffe and Ingham 13 (13): 1643 -- Genes and Development
The notochord is a defining characteristic of the chordate embryo.
of notochord function that remain to be understood.
Conservation of the developmental role of Brachyury in notochord formation in a urochordate, the ascidian Halocynthia roretzi.
www.genesdev.org /cgi/content/full/13/13/1643   (2483 words)

 {beta}-Catenin controls cell sorting at the notochord-somite boundary independently of cadherin-mediated adhesion -- ...
Arrow represents the anterior (a) to posterior (p) orientation of the notochord sketch.
of notochord and somitic tissue because in 44% of the embryos,
E-expressing cells are rounded, and the notochord morphology is perturbed (compare A with Fig.
www.jcb.org /cgi/content/full/170/4/675   (6458 words)

 The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation -- Ben ...
embryos, the notochord phenotype was assessed by eGFP fluorescence.
All genotypes showed disruptions of the notochord in and caudal to the sacral region (arrows), or a discontinuous caudal notochord with scattered displaced notochord remnants (arrowheads).
The notochord in the posterior trunk and tail region of heterozygous
www.genesdev.org /cgi/content/full/18/14/1725   (6492 words)

 TheFetus.net - Split notochord syndrome -Philippe Jeanty, MD, PhD
The terminal, dorsal part of the enteric fistula, which is produced between the endoderm and the ectoderm through a partially duplicated notochord in the development of the embryo, remains after obliteration of the fistula and, consequently, the mucosa of the enteric remnant is inverted and projects through the skin of the back
Kiristioglu I, Teitelbaum DH, Dogruyol H Split notochord syndrome with prolapsed congenital colostomy.
Kheradpir MH, Ameri MR Dorsal herniation of the gut with posterior opening of the terminal colon: a rare manifestation of the split notochord syndrome.
www.thefetus.net /page.php?id=443   (671 words)

 A High-Affinity Hemoglobin Is Expressed in the Notochord of Amphioxus, Branchiostoma californiense -- Bishop et al. 195 ...
A High-Affinity Hemoglobin Is Expressed in the Notochord of Amphioxus, Branchiostoma californiense -- Bishop et al.
Hemoglobin is expressed in myotome tissue and in notochord cells within the
The notochord Hb may be involved in facilitating oxygen delivery and providing a short-term
www.biolbull.org /cgi/content/abstract/195/3/255   (248 words)

 [No title]   (Site not responding. Last check: 2007-10-21)
Synthesized and released by notochord initially (and floor plate later) at times when ventral cell types are being generated 2.
FP is not induced within the neural tube by the notochord, but is formed along with notochord in a common mesodermal cell population.
(b) The allocation model postulates a common origin of notochord and FP in Hensen's node, with FP precursor cells invading the overlying neural plate (fl arrows).
nsm1.utdallas.edu /bio/Dmello/DEV-NEURO/Morphogenesis/LECTURE.doc   (1836 words)

 notochord - The Columbia Encyclopedia, Sixth Edition - HighBeam Research   (Site not responding. Last check: 2007-10-21)
notochord - The Columbia Encyclopedia, Sixth Edition - HighBeam Research
NOTOCHORD [notochord], in biology, supporting rod running most of the length of animals of the phylum Chordata and present at varying times in the life cycle.
Our archive contains millions of documents from thousands of sources and goes back over 23 years.
www.highbeam.com /doc/1E1:notochor/notochord.html?refid=ip_hf   (75 words)

 The Oxford American College Dictionary: notochord @ HighBeam Research   (Site not responding. Last check: 2007-10-21)
The Oxford American College Dictionary: notochord @ HighBeam Research
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www.highbeam.com /doc/1O997:notochord/notochord.html?refid=ip_hf   (96 words)

 VE Glossary   (Site not responding. Last check: 2007-10-21)
Ectodermal tube formed by union of two neural folds; Dorsal midline structure induced by notochord that forms brain in cranial region and spinal cord in more caudal regions
Thickened endoderm rostral to notochordal process; becomes part of oral membrane
Mesoderm with embryonic origin on either side of the notochord; Develops into series of somites, mesenchymes and vertebral columns
www.visembryo.com /baby/gloss.html   (4499 words)

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