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| | UB Department of Biological Sciences: Ronald Berezney |
 | | Using combined structural, molecular, and computer imaging approaches, we are studying the functional organization, assembly, and cell cycle regulation of higher order units of replication, transcription and RNA splicing in the cell nucleus. |
 | | We are investigating the 3-D organization and dynamics of chromosome territories, subchromosomal domains and individual genes in the interphase cell nucleus in relationship to replication, transcription and splicing factor domains. |
 | | These include the genomic organization and regulation of nuclear matrin 3 and the analysis, nuclear assembly, cell cycle regulation, and functional properties of a recently discovered cyclophilin-type nuclear matrix protein, termed matrin cyp (cyclophilin), which co-localizes in three-dimensions with splicing component domains inside the cell nucleus. |
| wings.buffalo.edu /academic/department/fnsm/bio-sci/faculty/berezney.html (665 words) |
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