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Floxin Otic   (Site not responding. Last check: 2007-10-16) Ofloxacin was present in high concentrations in otorrhea (389-2850 µg/g, n=13) 30 minutes after otic administration of a 0.3% solution in subjects with chronic suppurative otitis media and perforated tympanic membranes. Ofloxacin was not mutagenic in the Ames test, the sister chromatid exchange assay (Chinese hamster and human cell lines), the unscheduled DNA synthesis (UDS) assay using human fibroblasts, the dominant lethal assay, or the mouse micro-nucleus assay. Ofloxacin has not been shown to have any adverse effects on the developing embryo or fetus at doses relevant to the amount of ofloxacin that will be delivered ototopically at the recommended clinical doses. www.gettingwell.com /disease_states/sponsored_content/otitismedia/floxin_otic_monograph.html   (3058 words)

Ofloxacin Oral   (Site not responding. Last check: 2007-10-16) Ofloxacin inhibits the activity of a bacterial enzyme (gyrase) that is necessary for proper DNA formation and replication. Ofloxacin passes into breast milk and may cause serious side effects in the nursing infant; use of the drug is discouraged when nursing. Ofloxacin is generally not recommended for use by persons under the age of 18, as it has been shown to interfere with bone development. www.wholehealthmd.com /print/view/1,1560,DR_460,00.html   (612 words)

University of Miami School of Medicine - Glossary - ofloxacin Ofloxacin is used to treat sexually transmitted diseases, such as gonorrhea and chlamydia, but is not effective against syphilis. Ofloxacin should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients receiving this medication. Ofloxacin should be avoided in children and adolescents under 18 years old, as safe use in these patients have not been established. www.med.miami.edu /glossary/art.asp?articlekey=752   (514 words)

MedlinePlus Drug Information: Ofloxacin Oral Ofloxacin is an antibiotic used to treat certain infections caused by bacteria, such as pneumonia; bronchitis; venereal disease (VD); and prostate, skin, and urinary tract infections. Ofloxacin comes as a tablet to take by mouth. Ofloxacin may make your skin sensitive to sunlight. www.nlm.nih.gov /medlineplus/druginfo/medmaster/a691005.html   (721 words)

Ofloxacin,Low Cost Ofloxacin,No Cost Ofloxacin,Canadian Ofloxacin,Free Ofloxacin,Discount Ofloxacin,Ofloxacin ...   (Site not responding. Last check: 2007-10-16) Ofloxacin may also be used for other problems as determined by your doctor. Ofloxacin may also cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Ofloxacin may rarely cause inflammation or even tearing of a tendon (the cord that attaches muscles to bones). www.wecaremedicalmall.org /ofloxacin.htm   (2855 words)

[No title]   (Site not responding. Last check: 2007-10-16) Clinically, ofloxacin is used to treat mild to moderate urinary tract infections, prostatitis, lower respiratory tract infections, and skin infections. Ofloxacin appears to cross the placenta and is excreted in breast milk. Ofloxacin is minimally metabolized in the liver, with 70—90% of an oral dose excreted unchanged in the urine within 36 hours of dosing. www.chwframe.staywellsolutionsonline.com /modules/goldstandard/monograph.asp?cpnum=450&name=Ofloxacin   (2195 words)

MedlinePlus Drug Information: Ofloxacin (Otic)   (Site not responding. Last check: 2007-10-16) Ofloxacin otic solution is used to treat infections of the ear canal. However, ofloxacin has not been shown to cause birth defects or other problems when given in doses comparable to the amount of ofloxacin that is found in the eardrops. Because there is a potential for serious adverse reactions from ofloxacin in nursing babies, mothers who are using this medicine and who wish to breast-feed should discuss this with their doctor. www.nlm.nih.gov /medlineplus/druginfo/uspdi/203447.html   (1149 words)

Topical preparation containing ofloxacin - Patent 4923862 The hydrogel can be prepared by dissolving Ofloxacin or S-compound in the ingredients (a), (d), and (e), and a part of the ingredient (g) to prepare a solution in high concentrations and uniformly mixing the solution with a hydrogel separately prepared from the ingredients (b), (c), and (f), and the rest of the ingredient (g). The Ofloxacin or S-compound as active ingredient may be in the form of its salt. The acute toxicity of Ofloxacin in mice is LD.sub.50 5450 mg/Kg, p.o. www.freepatentsonline.com /4923862.html   (2212 words)

Ofloxacin: an overview Anthrax: ofloxacin is an alternative to ciprofloxacin used when there are contraindications to the use of ciprofloxacin itself. Ofloxacin inhibits an enzyme called DNA gyrase that is an essential component of the mechanism that passes genetic information onto daughter cells when a cell divides. Ofloxacin is a racemic mixture of which levofloxacin is the active component. www.cbwinfo.com /Pharmaceuticals/Ofloxacin.html   (281 words)

ofloxacin of Augusta, Georgia Ofloxacin is used to treat various bacterial infections such as bronchitis, pneumonia, chlamydia, gonorrhea, skin infections, urinary tract infections, and infections of the prostate. Ofloxacin is in the FDA pregnancy category C. This means that it is not known whether ofloxacin will be harmful to an unborn baby. Ofloxacin is not approved for use by children younger than 12 years of age. www.universityhealth.org /16723.cfm   (1331 words)

ofloxacin otic, Eastern Carolina You may not be able to use ofloxacin otic, or you may require a dosage adjustment or special monitoring during treatment. Ofloxacin otic is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not use ofloxacin otic without first talking to your doctor if you are pregnant or could become pregnant during treatment. www.uhseast.com /139993.cfm   (1295 words)

ADAP drugs: ofloxacin   (Site not responding. Last check: 2007-10-16) Ofloxacin is an anti-infective drug used for the treatment of lower respiratory infections, skin infection, and urinary tract infections including prostatitis, gonorrhea, cervicitis and urethritis. Ofloxacin has broad activity against bacterial infections and is used in combination with other drugs to treat tuberculosis. Ofloxacin is given in pill form, 200-400 mg every 12 hours on an empty stomach at least 1 hour before or 2 hours after meals with a full glass of water. www.atdn.org /access/drugs/oflo.html   (317 words)

Effects of Probenecid and Cimetidine on Renal Disposition of Ofloxacin in Rats -- Foote and Halstenson 42 (2): 456 -- ... Ofloxacin is a quinolone antibacterial agent which possesses broad activity against both gram-positive and gram-negative organisms. Ofloxacin's free fraction was determined to be 74% ± 0.06%. The CL of ofloxacin was significantly reduced in the presence of cimetidine. aac.asm.org /cgi/content/full/42/2/456   (1995 words)

Ofloxacin Otic   (Site not responding. Last check: 2007-10-16) Ofloxacin inhibits the activity of a bacterial enzyme (gyrase) that is necessary for proper DNA replication and repair. It is not known whether ofloxacin passes into breast milk after administration to the ear; caution is advised. An overdose with ofloxacin otic is unlikely to occur. www.wholehealthmd.com /refshelf/drugs_view/0,1524,811,00.html   (517 words)

Floxin Online, Description, Chemistry, Ingredients - Ofloxacin - RxList Monographs Chemically, ofloxacin, a fluorinated carboxyquinolone, is the racemate, (±)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylic acid. Ofloxacin is an off-white to pale yellow crystalline powder. The relative solubility characteristics of ofloxacin at room temperature, as defined by USP nomenclature, indicate that ofloxacin is considered to be soluble in aqueous solutions with pH between 2 and 5. www.rxlist.com /cgi/generic/oflox.htm   (161 words)

Ofloxacin, Eastern Carolina Ofloxacin is available in special preparations to treat eye infections and ear infections. Ofloxacin should be taken four hours before or two hours after consuming antacids (Maalox®, Mylanta®, Tumms®, Rolaids® and others) that may contain these minerals and mineral-containing supplements. A common side effect of antibiotics is diarrhea, which may be caused by the elimination of beneficial bacteria normally found in the colon. www.uhseast.com /116688.cfm   (655 words)

CHEST: Comparative roles of levofloxacin and ofloxacin in the treatment of multidrug-resistant tuberculosis : ...   (Site not responding. Last check: 2007-10-16) Bacillary susceptibility to ofloxacin, good adherence, radiographic extent of one lung or less, and use of levofloxacin were independent predictors of favorable outcome (odds ratios, 7.6 to 21.3). The efficacy of levofloxacin and ofloxacin was compared further by examining their respective success rates stratified according to the number of adverse factors present. The dosage of ofloxacin was slightly higher than that of levofloxacin only for those patients who harbored bacilli resistant to ofloxacin in vitro. www.findarticles.com /p/articles/mi_m0984/is_4_124/ai_110218178   (1268 words)

BioMed Central | Full text | Ofloxacin plus Rifampicin versus Doxycycline plus Rifampicin in the treatment of ... Ofloxacin plus rifampicin therapy has advantages of shorter treatment duration and provided shorter course of fever with treatment than in doxycycline plus rifampicin therapy. Ciprofloxacin and ofloxacin are particularly active in vitro against brucella infections [8]. Although, ofloxacin plus rifampicin decreased the duration of the therapy and provided shorter course of fever, however these superiorities are not sufficient for declaring this treatment as treatment of choice. www.biomedcentral.com /1471-2334/4/18   (2918 words)

Penetration of topical, oral, and combined administered ofloxacin into the subretinal fluid -- Çekiç et ... Ofloxacin is a fluoroquinolone antibiotic with rapid bactericidal activity interfering with DNA gyrase of bacteria. Ofloxacin was measured by using an HPLC method that involves direct injection of the samples. The ocular absorption of ofloxacin was shown to be increased in the inflamed eye. bjo.bmjjournals.com /cgi/content/full/83/10/1183   (1544 words)

Pharmacodynamics of Trovafloxacin, Ofloxacin, and Ciprofloxacin against Streptococcus pneumoniae in an In Vitro ... of trovafloxacin, ofloxacin, and ciprofloxacin in uninfected chambers, Ofloxacin and ciprofloxacin MICs ranged from 1 to 2 µg/ml for all eight strains. Similar to ofloxacin, the rates of killing with ciprofloxacin were consistently slower than those observed with trovafloxacin. aac.asm.org /cgi/content/full/43/5/1118   (3789 words)

Ofloxacin with or without stimulating colony-factors in the treatment of neutropenic fever   (Site not responding. Last check: 2007-10-16) We had to add another antibiotic or substituted the ofloxacin for fail in treatment, in 14% of the episodes. The results with ofloxacin in monotherapy were similar to the results with another broad-spectrum antibiotics; the advantage of this treatment was its oral administration after the acute phase. Ofloxacin had more easy administration and reduced the number of days in hospital. www.esmo.org /reference/abstracts/psc/724.htm   (308 words)

ofloxacin   (Site not responding. Last check: 2007-10-16) You may not be able to take ofloxacin or you may need a dosage adjustment or special monitoring during treatment. Ofloxacin may increase the risk of seizures if you have an existing seizure disease. Ofloxacin should not be taken by children under 12 years of age. www.envisionrx.com /HTMLICONS/D00114A1.htm   (953 words)

ofloxacin - Womens Health and Medical Information on MedicineNet.com STORAGE: Ofloxacin should be stored in a tight container and below 86 degrees F. Ofloxacin is used to treat pneumonia and bronchitis caused by Haemophilus influenzae and Streptococcus pneumoniae. Ofloxacin is often used to treat urinary infections and prostate infections caused by E. Coli. Ofloxacin can enhance the action of the anticoagulant warfarin (Coumadin), and increase the risk of bleeding. www.medicinenet.com /ofloxacin/article.htm   (657 words)

Ofloxacin - Talk Medical · Ofloxacin is used to treat various bacterial infections such as bronchitis, pneumonia, chlamydia, gonorrhea, skin infections, urinary tract infections, and infections of the prostate. · Ofloxacin is in the FDA pregnancy category C. This means that it is not known whether Ofloxacin will be harmful to an unborn baby. Ofloxacin increases the sensitivity of the skin to sunlight, and severe sunburning may result. www.talkmedical.com /medications/4463/Ofloxacin   (873 words)

Outcomes of Patients With Multidrug-Resistant Pulmonary Tuberculosis Treated With Ofloxacin/Levofloxacin-Containing ... Ofloxacin was used in 53 patients and levofloxacin in vitro and efficacy in vivo for ofloxacin. Hong Kong Chest Service/British Medical Research Council (1992) A controlled study of rifabutin and an uncontrolled study of ofloxacin in the retreatment of patients with pulmonary tuberculosis resistant to isoniazid, streptomycin and rifampicin. www.chestjournal.org /cgi/content/full/117/3/744   (3660 words)

Ofloxacin (Ophthalmic) Ofloxacin (oh-FLOKS-a-sin) is an antibiotic used to treat bacterial infections of the eye, such as conjunctivitis and corneal ulcers. However, studies in animals that were given very high doses of ofloxacin by mouth have shown that ofloxacin can cause birth defects or other problems. There is no specific information comparing use of ophthalmic ofloxacin in the elderly with use in other age groups. allnutritionals.com /drugs/o/ofloxacin-ophthalmic.shtml   (1126 words)

MedlinePlus Drug Information: Ofloxacin Injection The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for at least 60 minutes or more, one or two times a day. Ofloxacin eliminates bacteria that cause many kinds of infections including pneumonia, and urinary tract, skin, bone, and heart infections. If you are receiving ofloxacin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). www.nlm.nih.gov /medlineplus/druginfo/medmaster/a694004.html   (769 words)

Ofloxacin, Floxin, Ocuflox Ofloxacin is a “fluoroquinolone” antibiotic used to treat bacterial infections. Ofloxacin is available in special preparations to treat eye infections and Ofloxacin may be taken with or without food; food slows the absorption but not the total amount of ofloxacin absorbed from. www.truestarhealth.com /Notes/1263005.html   (720 words)

IngentaConnect Ofloxacin: A Reappraisal of its Use in the Management of Genitour...   (Site not responding. Last check: 2007-10-16) Ofloxacin is an established fluoroquinolone agent which achieves good concentrations in genitourinary tract tissues and fluids. Ofloxacin demonstrates consistent efficacy in a broad range of urinary tract infections, achieving bacteriological response rates in excess of 80% in uncomplicated and 70% in complicated infections. Ofloxacin is also effective as a single-dose regimen in the treatment of uncomplicated gonorrhoea, as a 7-day regimen in uncomplicated C. api.ingentaconnect.com /content/adis/dgs/1998/00000056/00000005/art00015   (447 words)

Ocuflox, Ofloxacin, side effects, drug interactions, overdose, dosage It is prescribed for eye inflammations and for ulcers or sores on the cornea (the transparent covering over the pupil). Ofloxacin, the active ingredient, is a member of the quinolone family of antibiotics. Other forms of ofloxacin have been known to cause allergic reactions in a few patients. www.pdrhealth.com /drug_info/rxdrugprofiles/drugs/ocu1640.shtml   (516 words)

Ranbaxy gets US nod for Ofloxacin According to a release issued to the BSE on Wednesday, the USFDA has determined Ranbaxy's ofloxacin tablets to be the bio-equivalent and therefore therapeutically equivalent to the listed drug (Floxin tablets of Ortho McNeil Pharmaceutical Inc). Ofloxacin will be launched in the US this month, and will made available through wholesalers and other distribution outlets, the release added. The stock is moving in a narrow range today, and was up a per cent (Rs 14) at Rs 1,037 on the BSE at 1230 hrs. www.rediff.com /money/2003/sep/03ranbaxy.htm   (114 words)

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