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Topic: Oligomer

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	Method for preparing difurfurylideneacetone oligomer - Patent 4281114
		This method for the production of difurfurylideneacetone oligomer is commercially realized; however, at the final stage the process of oligomerization of difurfurylideneacetone in the presence of an acid catalyst occurs but with a very high speed which hinders the possibility of determination of the degree of readiness of the oligomer.
		The oligomer with the required properties has a life time of several minutes only (5-15 minutes), during which period it is impossible to determine its dropping point due to a long time required for the analysis.
		This oligomer, when mixed with graphite in the manufacture of graphitized plastics, should be subjected to rolling for a period of 5 to 8 minutes.
	www.freepatentsonline.com /4281114.html (2228 words)

	Oligomer Porphyrins - Their Potential as Molecular Wires
		The oligomer porphyrin system, based on 5,10,15,20-tetrakis(3,5-di-tert-butylphenyl)porphyrin in which the porphyrin rings are bridged by coplanar aromatic systems and the ends are capped with phenanthroline, is proposed to meet all the criteria for a molecular wire.
		This oligomer porphyrin system has a fully conjugated *-electron conduction pathway which is surrounded by a sheath of bulky insulating lipophilic alkyl groups that will act to minimise random conduction, such as electrostatic interactions and electron tunnelling, and improve solubility.
		An outline of the synthesis of the oligomer porphyrin systems from various building blocks is presented, along with general protocols for the synthesis of oligomer porphyrin systems of varying lengths.
	www.foresight.org /conferences/MNT8/Abstracts/Crossley (344 words)

	Patent 6,455,495
		The negatively charged peptide oligomer, also referred to herein a peptide oligomer having negatively charged amino acids, has an affinity for the hydroxyapatite component of bone tissue and thereby binds to the bone tissue and brings the therapeutic agent with which it is conjugated into close contact with the bone tissue.
		By varying the total negative charge of the peptide oligomers as well as the ratio of total negative charge to number of amino acid residues in the peptide oligomer, a wide range of binding affinities of the peptide oligomer for bone tissue is provided.
		Conjugation of a negatively charged peptide oligomer to an imaging agent can be effected by well known procedures in the art, including having the negatively charged peptide oligomer complex a radionuclide directly, or by chemical conjugation of the negatively charged peptide oligomer with a coordination complex of a radionuclide and a chelating agent.
	www.pharmcast.com /Patents/Yr2002/September2002/092402/6455495_Bone092402.htm (3801 words)

	Curable polyester oligomer and a process for producing same - Patent 4191714
		The polyester oligomer of claim 1, or claim 2, wherein said silyl radical is at least at the side chain and at the ends of the molecule.
		The polyester oligomer of claim 1 wherein said oligomer is admixed with a filler.
		Among the polyester oligomers to be subjected to the hydrosilylation reaction are thos which contain hydroxy radicals in the molecule.
	www.freepatentsonline.com /4191714.html (4511 words)

	Oligomer - Wikipedia, the free encyclopedia
		In chemistry, an oligomer consists of a finite number of monomer units ("oligo" is Greek for "a few"), in contrast to a polymer which, at least in principle, consists of an infinite number of monomers.
		In biochemistry, the term oligomer is used for short, single stranded DNA fragments, generally used in hybridization experiments (bound to glass slides or nylon membranes).
		It can also refer to a protein complex made of two or more subunits.
	en.wikipedia.org /wiki/Oligomer (166 words)

	Probable Quaternary Structures
		Many proteins normally exist as oligomers, but the oligomer is often incomplete in the published PDB file.
		In order for PQS to report a specific oligomer, that oligomer must occur in the crystal, or else the authors of the PDB file must specify the symmetry operations required to generate the oligomer (commonly done for virus capsids).
		The specific oligomer may be a complete virus capsid, such as for poliovirus (2plv), or simian virus 40 (1sva).
	molvis.sdsc.edu /protexpl/pqs.htm?id=1E12 (923 words)

	Other Oligomer Products - Bomar Specialties Company - UV/EB Curing Advanced Performance Oligomers
		This oligomer family is specifically designed for electronic and electrical applications, possessing classic PBD properties combined with urethane characteristics, made UV/EB curable.
		With up to 15 functional groups, this oligomer is ideally suited for use as a co-oligomer in UV/EB formulations where enhanced abrasion and scratch resistnace properties are required.
		Oligomers combining characteristics of silicones with that of urethance and possessing acrylate functionality for UV/EB curing.
	www.bomarspecialties.com /products/selector_guide_other.asp (422 words)

	UV/EB Curing Advanced Performance Oligomer Products - Bomar Specialties Company
		The aromatic oligomers provide similar physical properties to that of the aliphatics, but are not recommended for applications where a non-yellowing film is critical.
		Oligomer designed to provide cure for dark or shadow areas of a coating, adhesive or ink.
		This oligomer is the highest functionality urethane acrylate that is commercially available in its class.
	www.bomarspecialties.com /products/products.asp (796 words)

	OLIGOMER manual
		The input data for oligomer is experimental scattering curve from a mixture of several dictinct components and a set of form-factors for each component of this mixture.
		Given the intensities from the components (form–factors), program oligomer finds the volume fractions by solving a system of linear equations using the algorithm of nonnegative or unconstrained least-squares to minimize the discrepancy between the experimental and calculated scattering curves.
		oligomer [ /ff ] [ ] [ /param1 ]...
	www.embl-hamburg.de /ExternalInfo/Research/Sax/oligman.html (632 words)

	Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers -- ...
		Drusen exhibit amyloid oligomer reactivity in the form of a core-like structure that accumulates centrally within drusen and in close proximity to the Bm.
		oligomers was observed in the presence of the oligomer-specific
		Amyloid oligomer cores are labeled with fluorescein (green), and lipofuscin autofluorescence in the RPE is visualized in red (Cy3 channel).
	www.jci.org /cgi/content/full/116/2/378 (4985 words)

	Pertussis Toxin B Oligomer
		The B oligomer of pertussis toxin is responsible for the binding of the holotoxin to eukaryotic cell surfaces and facilitates the entry of A protomer (S-1) into receptive cells.
		In the intact toxin, B oligomer is noncovalently bound to S-1, which is the enzymatic component of the holotoxin.
		B oligomer is as effective on a molar basis as the holotoxin in agglutinating goose erythrocytes.
	www.listlabs.com /Literature/183.htm (337 words)

	Hamilton \| HPLC Columns \| Separation and Purification of DNA (Site not responding. Last check: 2007-10-30)
		Collect and treat the oligomer for 30 minutes with 500 µL of 80% acetic acid to remove the acid labile dimethoxytrityl (DMT) protecting group from the oligomer.
		The larger the oligomer, the smaller the column capacity.
		The method of detection for oligomer separation and purification is UV at either 254 nm, 260 nm, or 297 nm.
	www.hamiltoncompany.com /product/hplc/separatdna.html (1121 words)

	Peptide conjugated, inosine-substituted antisense oligomer compound and method patent invention
		[0002] This invention relates to an antisense oligomer compound (i) conjugated to an arginine rich-peptide effective to enhance the uptake of the oligomer into cells, and (ii) in which strings of G bases are broken by one of more inosine bases, and methods of using such compound.
		Although the basis of this problem is not understood, it appears to involve an interaction between the positively charged peptide and the oligomer compound in a way that promotes the formation of G-quartets in the oligomer, thus reducing the solubility and/or ability of the compound to bind to its target nucleic acid.
		It would therefore be useful to enhance the cellular uptake of such antisense oligomer compounds, by conjugating the compound with an arginine-rich peptide, without degrading the antisense activity of the compound with respect to its intracellular target.
	www.freshpatents.com /Peptide-conjugated-inosine-substituted-antisense-oligomer-compound-and-method-dt20051229ptan20050288246.php (1349 words)

	Mechanism of Chaperone Function in Small Heat Shock Proteins: DISSOCIATION OF THE HSP27 OLIGOMER IS REQUIRED FOR ...
		oligomer equilibrium of Hsp27 was perturbed by mutations that
		Oligomer equilibrium of Hsp27 as observed by SEC.
		of the native oligomer implies that the interconversion of the
	www.jbc.org /cgi/content/full/280/7/5281 (5679 words)

	Amir Faraji - UF Journal of Undergraduate Research Paper
		The tetrahedral platinum-acetylide oligomer with a central adamantane anchor.
		Moreover, when preparing large oligomers or polymers, one of the most influential decisions on these polymerizations is selecting an appropriate palladium catalyst.
		The preparation of platinum-acetylide oligomers and polymers requires the attentive selection of reaction solvents in addition to the use of the aforementioned catalysts.
	www.clas.ufl.edu /jur/200601/papers/paper_faraji.html (3104 words)

	Amazon.com: oligomer (Site not responding. Last check: 2007-10-30)
		New low-viscosity acrylic-urethane prepolymers and their acrylated oligomers for moisture and UV-curable coatings.(Technology Today): An article from: JCT Research by Daniel B. Pourreau and Scott Smyth (April 1, 2005)
		On the in-situ polymerization of cyclic butylene terephthalate oligomers: DSC and rheological studies.: An article from: Polymer Engineering and Science by Z.A. Mohd Ishak, K.G. Gatos, and J. Karger-Kocsis (Jun 1, 2006)
		Conjugated oligomers, polymers, and dendrimers: From polyacetylene to DNA : proceedings of the Fourth Francqui Colloqium, 21-23 October 1998, Brussels...
	www.amazon.com /s?ie=UTF8&search-alias=aps&keywords=oligomer&page=1 (494 words)

	Binding Component of Clostridium perfringens Iota-Toxin Induces Endocytosis in Vero Cells -- Nagahama et al. 70 (4): ...
		Vero cells were incubated with rIb or the oligomer at 37°C. concentrations in the medium were determined at given times by atomic absorption spectrometer.
		that the oligomer is not released from the cells.
		that the oligomer was gradually degraded in the cells.
	iai.asm.org /cgi/content/full/70/4/1909 (4252 words)

	Low Viscosity and Good Flow Ink Systems Developed with a Polyester Acrylate Oligomer and Low Skin Irritation Monomers - ... (Site not responding. Last check: 2007-10-30)
		The study verified that the CN-2200 oligomer is a superior-performing oligomer for ink applications, and that many other monomers outperform TMPTA in ink dispersions formulated using the polyester acrylate oligomer.
		Following dispersion of the pigment in the oligomer, monomers were added to dilute the pigment to a level of 25% by weight.
		In the absence of pigment, all of the acrylate oligomer blends have Newtonian flow, and the viscosity is independent of shear rate.
	www.pcimag.com /CDA/Archives/01bbb044256a7010VgnVCM100000f932a8c0____ (1483 words)

	Prion propagation: Avoiding the toxic oligomer
		It is not clear, however, whether amyloids follow a progression from monomer to oligomer to plaque.
		Oligomers, which are typically seen when other proteins form amyloids, have also been seen during this process, some of them near NM fiber ends.
		To investigate the role of oligomers in NM amyloid formation and growth, the researchers explored the relationship between monomer concentration and polymerization progress.
	www.eurekalert.org /pub_releases/2004-09/plos-ppa091404.php (612 words)

	Monomer, Oligomer and Polymer Analytical Services (Site not responding. Last check: 2007-10-30)
		Polymers studied in the laboratory include a large range of performance polymers such as acrylics, polyesters, polyethers, polyurethanes and naturally derived polymers such as cellulosics, carbohydrates and polysaccharides, and biological polymers.
		Oligomers studied include a range of functional prepolymers, telechelic oligomers and branched oligomers of various architectures.
		Applications studied have included development of reactive oligomers for UV curing formulations, new surface coating and ink formulations, residual monomers in food related applications and reactive oligomers for modification of pharmaceutical small molecule API’s and for grafting on to biological molecules such as proteins for synthetic post translational modification.
	www.intertek-cb.com /newsitetest/services/asg/monomeroligomerpolymeranalysis.shtml (233 words)

	Computational identification of cis-acting elements affecting post-transcriptional control of gene expression in ...
		As described in the text, oligomers were counted and analyzed in the coding region (including introns) of 225 genes containing introns.
		As described in the text, oligomers were counted and analyzed in the 3'-UTR of 281 genes encoding mitochondrial proteins.
		oligomer representation in the 3'-UTR sequences of the 58 genes
	nar.oxfordjournals.org /cgi/content/full/28/7/1604 (6742 words)

	CYCLIC OLIGOMER NANOCOMPOSITES (WO0024818A1)
		In one embodiment of the method, the cyclic oligomer is a macrocycle and the method involves opening the macrocycle and polymerizing the opened macrocycle to produce a suitable nanocomposite polymer.
		In another embodiment of the method, the cyclic oligomer is a polycycle and the method involves combining the polycycle with at least one low melt viscosity polymer to form another suitable nanocomposite polymer.
		Preferred are macrocyclic oligomers that have a melting temperature of from between about 150'C to about 250'C. Additionally preferred macrocyclic oligomers have a glass transition temperature of from between about 250'C to about 300'C. Other preferred macrocyclic oligomers have a thermal decomposition temperature of at least about 450'C. Forward References:
	www.delphion.com /details?&pn=WO00024818A1 (495 words)

	Efficacy of Antisense Morpholino Oligomer Targeted to c-myc in Prostate Cancer Xenograft Murine Model and a Phase I ... (Site not responding. Last check: 2007-10-30)
		Efficacy of Antisense Morpholino Oligomer Targeted to c-myc in Prostate Cancer Xenograft Murine Model and a Phase I Safety Study in Humans -- Iversen et al.
		The bold sequences represent the mismatch in the scrambled oligomers.
		The antisense c-myc oligomer (AVI-4126) and the corresponding
	clincancerres.aacrjournals.org /cgi/content/full/9/7/2510 (5405 words)

	Immune stimulation by an antisense oligomer complementary to the rev gene of HIV-1.
		Immune stimulation by an antisense oligomer complementary to the rev gene of HIV-1.
		Mice developed massive splenomegaly and polyclonal hypergammaglobulinemia within 2 days after intravenous injection of a phosphorothioate oligomer that is antisense to a portion of the rev region of the HIV-1 genome.
		Similar immunologic effects were observed with an anti-rev 21-mer phosphorothioate, truncated at the 3' end, but not with a 20-mer human p53 antisense phosphorothioate or a 28-mer anti-rev phosphodiester.
	www.aegis.com /aidsline/1993/sep/M9390589.html (451 words)

	Use of a Locked-Nucleic-Acid Oligomer in the Clamped-Probe Assay for Detection of a Minority Pfcrt K76T Mutant ...
		Use of a Locked-Nucleic-Acid Oligomer in the Clamped-Probe Assay for Detection of a Minority Pfcrt K76T Mutant Population of Plasmodium falciparum -- Senescau et al.
		Use of a Locked-Nucleic-Acid Oligomer in the Clamped-Probe Assay for Detection of a Minority Pfcrt K76T Mutant Population of Plasmodium falciparum
		LNA oligomer concentration was tested in the range of 1 to 4
	jcm.asm.org /cgi/content/full/43/7/3304 (2608 words)

	Detergent-Resistant Membrane Microdomains Facilitate Ib Oligomer Formation and Biological Activity of Clostridium ...
		Ib oligomers are found in DRMs of iota-toxin-susceptible cells.
		Ib oligomers were not found in DRMs (Fig.
		that facilitate rapid formation of oligomers (3, 17, 19, 22).
	iai.asm.org /cgi/content/full/72/4/2186 (4533 words)

	Sequence-Dependent Dynamics of TATA-Box Binding Sites -- Flatters and Lavery 75 (1): 372 -- Biophysical Journal
		oligomer underwent a spontaneous transition to a conformation
		We begin by considering the overall helical conformation obtained during the simulations of the S2 oligomer.
		The comparison is made for using conformations of each oligomer occurring at ~550 ps into the simulation as is limited to the central 12 bp of each sequence.
	www.biophysj.org /cgi/content/full/75/1/372 (4443 words)

	A Maternal Smad Protein Regulates Early Embryonic Apoptosis in Xenopus laevis -- Miyanaga et al. 22 (5): 1317 -- ...
		Oligomer 1 is a sense strand sequence used as a control.
		(B) Four of the oligomers (oligomers 3, 6, 11, and 12) and the control oligomer 1 were synthesized using modified phosphorothioates to increase stability and decrease toxicity.
		Results of similar experiments using the control sense strand oligomer 1 and a different antisense oligomer (oligomer 12) are also shown.
	mcb.asm.org /cgi/content/full/22/5/1317 (6910 words)

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