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Topic: Oligomeric proanthocyanidin

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	Oligomeric proanthocyanidin - Wikipedia, the free encyclopedia
		Oligomeric proanthocyanidins or OPCs are a class of flavonoid complexes found in grape seeds and skin, that act as antioxidants (free radical scavengers) in the human body.
		Proanthocyanidins-also called "OPCs" for oligomeric proanthocyanidins and "PCOs" for procyanicolic oligomers are a class of nutrients belonging to the bioflavonoid family.
		Proanthocyanidins have antioxidant activity and they play a role in the stabilization of collagen and maintenance of elastin—two critical proteins in connective tissue that support organs, joints, blood vessels, and muscle.
	en.wikipedia.org /wiki/Oligomeric_proanthocyanidin (939 words)

	Oligomeric Proanthocyanidin (Site not responding. Last check: 2007-11-05)
		Proanthocyanidins belong to the category known as condensed tannins, one of the two main categories of plant tannins (Table 2).
		Proanthocyanidins are high-molecular-weight polymers comprised of the monomeric unit flavan-3-ol ((+)catechin and (-) epicatechin).
		Oligomeric proanthocyanidin complexes are primarily known for their free radical scavenging and antioxidant activity.
	www.thorne.com /altmedrev/fulltext/oligo5-2.html (2129 words)

	Your Vital Health (Site not responding. Last check: 2007-11-05)
		Proanthocyanidins are virtually identical whether they come from pine bark, grape seeds, lemon tree bark, cranberries, or hazel nut tree leaves.
		Proanthocyanidin is a specific class of bioflavanoids found in a wide number of plants, including purple, red and white grapes, as well as pine bark, lemon tree bark, hazel nut tree leaves, blue berries, cherries, cranberries and others.
		Proanthocyanidin has been shown to be the active principle that makes both pine bark and Grape Seed Extract so effective as an antioxidant and collagen and elastin protector.
	www.nutracor.com /hcc/hcc_antioxid.html (2246 words)

	Antioxidant Grape Seeds Extract, Oligomeric Proanthocyanidins, OPC
		Proanthocyanidins, also known as OPCs and leukocyanidins — to cite only their most common names — are a group of bioflavonoids which, until 1936, were known as Vitamin P. The discovery of proanthocyanidins is attributed to a Frenchman, Professor Jacques Masquelier, who devoted a half century to researching them.
		Oligomeric proanthocyanidin or proanthocyanidins, often used interchangeable, are clusters of phenolic compounds built from single monomer units called catechin and epi-catechin.
		Although the definition of oligomeric varies somewhat, dimers (two units), trimers (three units) and sometimes up to heptamers (seven units) are generally referred to as oligomeric while larger complexes are referred to as polymeric and/or tannins.
	www.nutrisana.com /canada/grape.seeds.extract.html (2393 words)

	DCNI \| Template
		This statement implies that the oligomeric proanthocyanidins have been quantified when there is currently no validated analytical method for the oligomeric proanthocyanidins.
		This statement again implies that the proanthocyanidins are measured as OPC, which is not precise and then attempts to qualify it by proclaiming the OPC consists of monomers and oligomers.
		A patented extract of the flavanol proanthocyanidins (PAC), prepared from the grape seeds…these are the most potent of the available proanthacyanidin extracts, since they have a higher total content of PAC (92 percent or greater).
	www.activin.com /LabelingGSE.html (1322 words)

	Plantain Seed P.E. (Site not responding. Last check: 2007-11-05)
		Although the majority of the studies conducted on OPCs have been done in cell culture (test tube) and animals, their ability to reduce free radical damage and oxidative stress suggest that they may be particularly effective in reducing the risk of cancer, cardiovascular disease and a number of the chronic diseases associated with aging.
		In some test models, proanthocyanidins are 50 times more potent antioxidants than the two most famous antioxidants, vitamins C and E. Sophisticated tests have shown proanthocyanidins to be powerful quenchers of the hydroxyl radical, the most damaging of all common free radicals, as well as lipid peroxides (rancid fats).
		Proanthocyanidins inhibit enzymes such as hyaluronidase, collagenase and elastase that can break down the collagen structure of blood vessel walls.1 This fact is especially important for brain health, due to the blood-brain barrier.
	www.sweepersonline.com /forum/posts/10405.html (5709 words)

	Polyphenolics :: Frequently Asked Questions
		Chemically speaking, the terms condensed tannin and proanthocyanidin can be used interchangeably and both are comprised of two or more flavan-3-ol units, but proanthocyanidin seems to be preferred in the nutraceutical industry.
		Proanthocyanidins come in a multitude of chemical structures and sizes consisting of base units called "monomers".
		This patent, titled "Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof," was issued October 6, 1987, to Jack Masquelier.
	www.polyphenolics.com /consumer_FAQ.html (945 words)

	The Facts about Pycnogenol and Grape Seed Extract
		Pycnogenol™ vs Grape Seed Extract Proanthocyanidin by Clark Hansen, N.M.D. The following excerpt is a response to some misinformation being reported by distributors of Kaire International and other companies regarding Pycnogenol™, a Proanthocyanidin extract of pine bark, in comparison to Proanthocyanidin extracted from grape seeds.
		Truth: Proanthocyanidins are virtually identical whether they come from pine bark, grape seeds, lemon tree bark, cranberries, or hazel nut tree leaves.
		Truth: Proanthocyanidin has been shown to be the active principle that makes both pine bark and Grape Seed Extract so effective as an antioxidant and collagen and elastin protector.
	members.tripod.com /~yourhealth/main/grapefact.htm (2468 words)

	Flavay : The Original and Patented OPC (Oligomeric Proanthocyanidin) Product
		Masquelier, J. Plant extract with a proanthocyanidins content as a therapeutic agent having radical scavenging effect and use thereof.
		Activite angioprotectrice des oligomeres procyanidolques chez l’animal-activite aniagoniste vis-a-vis des mediateurs de l’inflamation.
		Dumon, M., Michaud, J., Masquelier, J. Proanthocyanidin content in vegetable extracts to be used in the preparation of medicines.
	www.aboutopc.com (3033 words)

	Oligomeric Proanthocyanidin - Health & Beauty - Compare Prices, Reviews and Buy at NexTag - Price - Review
		This economical formula combines the powerful polyphenols of green tea with the oligomeric proanthocyanidins found in pine bark and grapeseeds to create a synergistic...
		Grapeseed extract (along with pine bark) are two of the main sources of OPC's (Oligomeric Proanthocyanidins).
		OPC-85 is a potent natural antioxidant derived from the bark of the European coastal pine, Pinus maritima.
	www.nextag.com /oligomeric-proanthocyanidin/search-html (394 words)

	Glossary O - Olive Oil, Onion, OPC (Oligomeric Proanthocyanidin), Osteoporosis
		OPC (Oligomeric Proanthocyanidin) is a potent antioxidant that neutralizes free radicals before they reach the LDL (“bad” cholesterol) to cause damage to our bodies.
		OPC (Oligomeric Proanthocyanidin) maintains the health or the arterial lining of blood vessels.
		An excellent source of OPC (Oligomeric Proanthocyanidin) is grape seeds.
	www.nutrition-info.com /glossary/Glossary-O.php (916 words)

	Oligomeric Proanthocyanidin - Find, Compare, and Buy at Shopping.com
		SolgarÂ’s Advanced Proanthocyanidin Compolex VEGICAPSÂ® are free of corn, yeast, wheat, soy and dairy...
		PROANTHOCYANIDINS Pine bark extract with antioxidant action *The term Â“pycnogenolÂ”...
		Oligomeric proanthocyanidins (OPC)is a natural substance derived from the bark of certain pine...
	www.shopping.com /xGS-Oligomeric_Proanthocyanidin (498 words)

	ThirdAge: OPCs (Oligomeric Proanthocyanidins)
		This substance consists of a family of chemicals known scientifically as oligomeric proanthocyanidin complexes (OPCs) or procyanidolic oligomers (PCOs).
		Effects of niacin-bound chromium and grape seed proanthocyanidin extract on the lipid profile of hypercholesterolemic subjects: a pilot study.
		Double-blind, placebo-controlled, randomised phase II trial of IH636 grape seed proanthocyanidin extract (GSPE) in patients with radiation-induced breast induration.
	www.thirdage.com /healthgate/files/21765.html (2752 words)

	[No title] (Site not responding. Last check: 2007-11-05)
		SP-303, an Antiviral Oligomeric Proanthocyanidin from the Latex of Croton lechleri (Sangre de Drago).
		SP-303 is a large oligomeric proanthocyanidin (condensed tannin) isolated from the latex of Croton lechleri, a species widely distributed throughout Central and South America.
		The red latex, also called sangre de drago ("dragon's blood"), is one of the most common traditional medicines in Latin America and is used by a wide variety of people, including indigenous, urban, and mestizo populations.
	www.herbalgram.org /tomsofmaine/herbclip/review.asp?i=41576 (504 words)

	Oligomeric Proanthocyanidins (OPCs) (Site not responding. Last check: 2007-11-05)
		Considerable research has explored therapeutic applications of oligomeric proanthocyanidin complexes (OPCs), naturally occurring plant metabolites widely available in grape seed and skin as well as in various fruits, vegetables, nuts, seeds, flowers, and bark.
		Ray SD, Parikh H, Hickey E, Bagchi M, Bagchi D. Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation.
		Upregulation of oxidant-induced VEGF expression in cultured keratinocytes by a grape seed proanthocyanidin extract.
	immupro.com /oligomeric.htm (532 words)

	Athletes.com - MRM Grape Seed Extract! Best Price!
		Studies show proanthocyanidins to have clinical benefit in cardiovascular health, glucose metabolism, supporting healthy cholesterol levels and improving skin elasticity.
		Grape Seed extract, also known as oligomeric proanthocyanidin complex, a class of flavonoids with powerful antioxidant properties (1,2).
		Percent value of OPCs in a formula is irrelevant, total milligrams of proanthocyanidin is the important factor.
	www.athletes.com /store/mrm/grape.html (463 words)

	Oligomeric Proanthocyanidin
		, 49(1), 45-54, 2003 Example of an Oligomeric proanthocyanidin in an Isotonic form www.opcxtra.com?aff=f45896 "Oligomeric Proanthocyanidin Complexes: History, Structure, and Phytopharmaceutical Applications".
		Description: Grape Seed Extract contains an oligomeric proanthocyanidin complex (OPC), a class of flavonoids with powerful antioxidant properties.
		Flavonoids are a group of compounds found naturally occurring in fruits, vegetables, nuts, seeds, flowe...
	seeds-guide.com /a/198780/Oligomeric+proanthocyanidin.html (1061 words)

	OPCs (Oligomeric Proanthocyanidins) - Wisconsin, Milwaukee, WI (Site not responding. Last check: 2007-11-05)
		Pecking A, Desprez-Curely JP, Megret G. Oligomeric grape flavanols (Endotelon W) in the treatment of secondary upper limb lymphedemas [translated from French].
		Thebaut JF, Thebaut P, Vin F. Study of Endotelon W in functional manifestations of peripheral venous insufficiency [translated from French].
		Delacroix P. Double-blind study of Endotelon W in chronic venous insufficiency [translated from French].
	www.columbia-stmarys.org /18305.cfm (2793 words)

	Grape Seed Extract Potent Antioxidant
		His method of extraction from the pine tree was patented in the early 1951, and further research showed the substance present in many plants such as, lemon tree bark, peanuts, hazel nuts, cranberries, blue berries, cherries, citrus peel, purple, red and white grape skins and seed purple grape seeds being the most concentrated source.
		Leucoanthocyanins (proanthocyanidins or OPCs, pycnogenols) are natural polyphenols belonging to the class of bioflavonoids.
		These proanthocyanidins – esters have been recently described as the most active substances in the battle against free radicals.”; October 1991 Martiliac, France (Procyanidines de France).
	www.positivehealth.com /permit/Articles/Antioxidant/costel16.htm (2208 words)

	OPC (Site not responding. Last check: 2007-11-05)
		Morazzoni, scientific director, stated “Grape procyanidins are a viable and clinically proven, bio-active antioxidant for the prevention of cardiovascular disease.”; Dr. Kendall, from the University of Birmingham in England, sited results from his clinical research using grape seed extract concluding antioxidants may play a role in sudden death prevention.
		While Oligomeric Proanthocyanidin complexes are primarily known for their free radical scavenging and antioxidant activity, they have also demonstrated anti-inflammatory, anti-viral, anti-bacterial, anti-carcinogenic and ant-allergic actions.
		They have also been proven to inhibit oxidation of human low-density lipoprotein and are used in the treatment of hypercholesterolemia.
	www.micromedonline.com /OPC.html (520 words)

	proanthocyanidin Sellers, Suppliers, Exporters, Manufacturers, Factories (Site not responding. Last check: 2007-11-05)
		Grape seed extract 95% oligomeric proanthocyanidins/OPC Product Name: Grape Seed P. Plant Origin: Vitis vinifera Specification: Oligomeric Proanthocyanidins 95% OPC UV What Is Grape Seed E....
		Grape seed Extract Oligomeric Proanthocyanidins are a set of bioflavonoid complexes that perform as free radical scavengers in human body.....
		Commodity:Grape seed Extract 1) Latin name: vitis vinifera L. 2) Specifications: 95% proanthocyanidin Functions and applications: As a dietary supplement, grape seed extract is rich in pol....
	www.fuzing.com /qrx/proanthocyanidin (571 words)

	Buy Olympian Labs Grape Seed Plus Twinpack 120mg, 100+100 caps (Site not responding. Last check: 2007-11-05)
		Oligomeric Procyanidins are a more potent anti-oxidant than those from pine bark.
		Pycnogenols is a chemical term used to distinguish the polyphenolic calls of bioflavonoids which contain Flavin-3-oils from the simpler bioflavonoids.
		Olympian Labs Grape Seed Extract, through a low temperature extraction method, is completely water soluble and free of dangerous solvents and food coloring additives.
	www.vitafly.com /yhst-73484102243733/olympian-grapeseed.html (212 words)

	BIOFLAVONOIDS: RESEARCH ARTICLES
		Pine bark and grape seed contain the flavonoids OPCs, which offer antioxidant protection against heart disease and cancer In the future, health care providers may hand out proanthocyanidin pills as readily as they recommend aspirin today.
		A steady stream of animal and in vitro studies supplemented by epidemiological evidence and a smattering of preliminary human studies reveal numerous health benefits associated with these compounds.
		They have some of the strongest physiological effects of any plant compounds, and they are also things of beauty: anthocyanins provide pigment for pansies, petunias, and plums.
	www.chiro.org /nutrition/bioflavonoids.shtml (678 words)

	+ International Clinic + (Site not responding. Last check: 2007-11-05)
		He named the active components of the pine bark pycnogenols.
		term was used to described an entire complex of proanthocyanidin
		proanthocyanidin extract: importance in human health and disease
	www.internationalclinic.co.kr /MI/content.asp?idx=50 (1869 words)

	Oligomeric Proanthocianidins - Quest for Health (Site not responding. Last check: 2007-11-05)
		Proanthocyanidins are a very powerful class of bioflavinoids, 50 times more powerful than Vitamin E and 20 times more powerful than Vitamin C.
		OPCs are derived from extracts of pine bark and grape seeds.
		Oligomeric Proanthocyanidins are availble in many formats and formulas but the key to efficient absorption into the bloodstream, so that they can be utilized by our bodies, lies in our digestive system.
	www.intercom.net /~ericr/q4hOPC.html (217 words)

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