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Topic: Oligopeptide


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In the News (Mon 6 Jul 09)

  
  Peptide-based inhibitors of HIV replication - Patent 5646120
Oligopeptides which bind TAR are identified in this assay by their characteristic, retarded migration on the gel, relative to TAR RNA to which no oligopeptide has bound.
Oligopeptides which differ from the basic domain in terms of amino acid sequence, either by way of addition, deletion or replacement of one or more amino acids including replacement of an L-amino by a corresponding D-amino acid, are referred to herein as "analogues" of the tat basic domain.
vi) an oligopeptide comprising from 6 to 11 arginines and one glutamine; and
www.freepatentsonline.com /5646120.html   (6660 words)

  
 Oligopeptide anticancer and antiviral agents - Patent 4912199
1 is a graph plotting the association constant of oligopeptides according to embodiments of this invention representative of the binding affinity of the oligopeptide to DNA vs. the length of the linking unit in the oligopeptide.
2 is a graph plotting the association constant of oligopeptides according to embodiments of this invention representative of the binding affinity of the oligopeptide to DNA vs. the length of the linking unit in the oligopeptide.
K.sub.a is an association constant of the DNA binding affinity of the oligopeptides in units of 10.sup.7 L.M.sup.-1.
www.freepatentsonline.com /4912199.html   (4221 words)

  
 SNL GeoBio LDRD - Biomolecular Interactions with Clay Minerals
(2000; 2001) limited their simulations to a small subset of simple proteins and oligopeptides, and used an inefficient valence forcefield that would be difficult to extend to large-scale simulations.
The results of the energy optimization for the isolated oligopeptide are presented in Figure 2.5.
In general, the molecular mechanics simulations suggest that clay surfaces are effective in creating significant nonbonded interactions between the clay and the oligopeptide.
www.sandia.gov /geobio/randy.html   (4812 words)

  
 Transport of L-Valine-Acyclovir Via the Oligopeptide Transporter In The Human Intestinal Cell Line, Caco-2 -- de Vrueh ...
uptake of cephalexin, a substrate for the oligopeptide transporter.
The uptake of cephalexin, a substrate for the intestinal oligopeptide transporter, in the presence or absence of acyclovir,
Cook TJ, Yan J and Sinko P (1997) Involvement of the organic cation and oligopeptide carrier proteins in the apical transport of valacyclovir across Caco-2 cell monolayers.
jpet.aspetjournals.org /cgi/content/full/286/3/1166   (3489 words)

  
 Genomic Structure of Proton-Coupled Oligopeptide Transporter hPEPT1 and pH-Sensing Regulatory Splice Variant.
Proton-coupled oligopeptide transporter PEPT1 facilitates the transport of dipeptides and peptoid drugs (including antibiotics) across the cell membranes of endothelial and epithelial cells.
Oligopeptide transporters are symporters driven by the flux of protons; they have a molecular architecture consisting of ~12 predicted TMSs.
Expression cloning of a mammalian proton-coupled oligopeptide transporter.
www.aapspharmsci.org /view.asp?art=ps030106   (2275 words)

  
 The specificity of oligopeptide transport by Streptococcus thermophilus resembles that of Lactococcus lactis and not ...
The specificity of oligopeptide transport by Streptococcus thermophilus resembles that of Lactococcus lactis and not that of pathogenic streptococci -- Juille et al.
The specificity of oligopeptide transport by Streptococcus thermophilus resembles that of Lactococcus lactis and not that of pathogenic streptococci
Lanfermeijer, F. C., Picon, A., Konings, W. and Poolman, B. Kinetics and consequences of binding of nona- and dodecapeptides to the oligopeptide binding protein (OppA) of Lactococcus lactis.
mic.sgmjournals.org /cgi/content/full/151/6/1987   (3528 words)

  
 Whey
VyoPro® Oligopeptide Whey Protein is a special advanced protein supplement designed to feed nitrogen hungry muscles the protein they need to stay in a proper “anabolic” state for maximum growth.
VyoPro Oligopeptide Whey Protein is processed under very delicate and critically monitored conditions designed to not only maintain protein integrity, but also to enhance the natural effectiveness and bioavailability of the whey fractions beyond their natural state.
Studies have shown that the whey oligopeptides used in VyoPro are 4 times more effective in increasing nitrogen retention in the body than either regular whey protein, whey peptides, or even free multi amino acid mixtures integrated together to mimic the structure of whey oligopeptides.
www.angelfire.com /on/fit98/1.html   (1210 words)

  
 Identification of a Differentially Expressed Oligopeptide Binding Protein (OppA2) in Streptococcus uberis by ...
The ami locus of the gram-positive bacterium Streptococcus pneumoniae is similar to binding protein-dependent transport operons of gram-negative bacteria.
Oligopeptide permease is required for expression of the Bacillus thuringiensis plcR regulon and for virulence.
Oligopeptides are the main source of nitrogen for Lactococcus lactis during growth in milk.
jb.asm.org /cgi/content/full/185/17/5210   (6541 words)

  
 Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease -- Adibi 285 (5): ...
The abundance of the oligopeptide transporter (Pept-1) in the
oligopeptide transporter of the brush-border membrane of the
The oligopeptides that escape hydrolysis by the cytoplasmic
ajpgi.physiology.org /cgi/content/full/285/5/G779   (6517 words)

  
 Supplementary material for
Oligopeptide frequency deviations from expectation, referred to on Page 24.
Three 4/5-column, tab delimited text files, with rows corresponding to either single residues, dipeptides, or tripeptides, respectively, which are listed in the first column.
The next column in oligopeptide files indicates whether the current oligopeptide is a homopeptide, heteropeptide or, in tripeptides, a palindrome.
www.weizmann.ac.il /sb/faculty_pages/Sussman/papers/suppl/Peer_2004   (491 words)

  
 SNL GeoBio LDRD
Results demonstrate that the nonbonded interactions are especially important in understanding the control of the structure and function of proteins as modified by inorganic substrates, and that the protein structure may be denatured by the clay surface.
Preliminary molecular simulations were completed to examine the intercalation of amino acids and oligopeptides in the interlayer of a clay mineral.
We use a hybrid energy forcefield allowing for the simultaneous simulation of both clay and oligopeptide to determine the general behavior of various amino acid side chains within the clay interlayer.
www.sandia.gov /geobio/MainPage.htm   (1631 words)

  
 Three Oligopeptide-binding Proteins Are Involved in the Oligopeptide Transport of Streptococcus thermophilus -- Garault ...
Three Oligopeptide-binding Proteins Are Involved in the Oligopeptide Transport of Streptococcus thermophilus -- Garault et al.
Oligopeptide transport systems are key channels between the environment and the inner part of micro-organisms, which have
Oligopeptide Uptake Is Essential to the Growth of S. thermophilus in Peptide-containing Media-- In addition to cell wall protease and the purine and branched-chain amino acid biosynthesis pathways, the oligopeptide transport
www.jbc.org /cgi/content/full/277/1/32   (4960 words)

  
 Determination of Oligopeptide Diversity within a Natural Population of Microcystis spp. (Cyanobacteria) by Typing ...
Determination of Oligopeptide Diversity within a Natural Population of Microcystis spp.
Molecular masses (m/z) oligopeptides and unknown components in the range of m/z 500 to 1,100 Da detected in colonies of M.
Molecular masses (m/z) of oligopeptides and unknown components in the range of m/z 500 to 1,100 Da detected in colonies of Microcystis spp.
aem.asm.org /cgi/content/full/67/11/5069   (3793 words)

  
 Peptide plus salt makes membrane - MIT News Office
Key to the assembly of the membrane is a special property of the oligopeptide: it is self complementary, meaning the side chains of individual oligopeptides can link together.
"It is the first self-complementary oligopeptide found in nature," said Dr. Shuguang Zhang, the postdoctoral fellow in Professor Rich's lab who discovered this property after isolating a yeast protein in which the oligopeptide was found.
For example the structure of the oligopeptide (named EAK16) is the same as that of the protein that makes up the beta-amyloid plaque characteristic of Alzheimer's and other diseases.
web.mit.edu /newsoffice/1993/peptide-0428.html   (498 words)

  
 Substrate directed formation of small biocatalysts under prebiotic conditions   (Site not responding. Last check: 2007-10-18)
We suggest that the unique recognition of certain amino acids of an enzyme by the substrate may be utilized for the preparation of specific catalytic oligopeptides.
To demonstrate that the formation of the active oligopeptide indeed involves the dimerization of two cysteins in a substrate-directed manner, we attempted to synthesize an
The active oligopeptide is not formed in absence of ONPG.
www.ch.ic.ac.uk /ectoc/ectoc-3/pub/044/ectoc.htm   (1760 words)

  
 [No title]
(786aa) 15 TMS, N-term is IN 3920.m00207small oligopeptide transporter, OPT familyo_sativachr_8P0605H023920
(763aa) 15 TMS, N-term is IN 3019.m00187small oligopeptide transporter, OPT familyo_sativachr_6P0425F023019
(766aa) 15 TMS, N-term is IN 3019.m00189small oligopeptide transporter, OPT familyo_sativachr_6P0425F023019
www.cbs.umn.edu /rice/osprotdb/fam499.htm   (107 words)

  
 EROP-Moscow
This database should now enable investigators to search easily for oligopeptides via a wide variety of different features, to compare their properties quickly, and to retrieve statistics about all relevant information in the database.
Because some oligopeptides are chemically modified at the N- and C-termini, six more symbols augment the standard one-letter code.
Tentative homologous family assignments, for each oligopeptide in EROP-Moscow, have been developed by sequence alignment, and the entire family on the Family page can be reached from the Peptide page via a "View family" button.
erop.inbi.ras.ru /help.php   (967 words)

  
 Direct conversion of an oligopeptide from a beta -sheet to an alpha -helix: A model for amyloid formation -- Zhang and ...
Direct conversion of an oligopeptide from a beta -sheet to an alpha -helix: A model for amyloid formation -- Zhang and Rich 94 (1): 23 -- Proceedings of the National Academy of Sciences
The oligopeptides were made by solid-phase synthesis on an Applied Biosystems model 430A.
Thermal stability of ionic self-complementary oligopeptides (Table 1).
www.pnas.org /cgi/content/full/94/1/23   (3259 words)

  
 Method for preparing zinc-oligopeptide easily absorbable by the human body page
A suspension of protein in deionized water at a neutral pH range in the presence of a protease is subjected to proteolysis to give a mixture of oligopeptides.
Zinc ions are chelated with the oligopeptides to give a zinc-oligopeptide solution.
Gli ioni dello zinco sono chelatati con i oligopeptides per dare una soluzione dello zinco-oligopeptide.
www.patentalert.com /docs/001/z00167531.shtml   (213 words)

  
 The Role of the N-Terminal Oligopeptide Repeats of the Yeast Sup35 Prion Protein in Propagation and Transmission of ...
The Role of the N-Terminal Oligopeptide Repeats of the Yeast Sup35 Prion Protein in Propagation and Transmission of Prion Variants -- Shkundina et al.
Articles by Shkundina, I. Articles by Ter-Avanesyan, M. The Role of the N-Terminal Oligopeptide Repeats of the Yeast Sup35 Prion Protein in Propagation and Transmission of Prion Variants
oligopeptide repeats was required, in contrast with the two
www.genetics.org /cgi/content/full/172/2/827   (3689 words)

  
 Human Proton/Oligopeptide Transporter (POT) Genes: Identification of Putative Human Genes Using Bioinformatics
The proton-dependent oligopeptide transporters (POT) gene family currently consists of ~70 cloned cDNAs derived from diverse organisms.
This class of secondary active transporters has broad selectivity for di- and tripeptides, whereas ability to transport longer peptides decreases drastically with increasing length.
An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2.
www.aapspharmsci.org /view.asp?art=ps020216   (5514 words)

  
 [No title]
At1g59740 Link to TAIR Link to Aramemnon (592aa) 12 TMS, N-term is IN oligopeptide transporter, putative / similar to oligopeptide transporter GI:510238 from [Arabidopsis thaliana]; supported by cDNA: gi_14334727_gb_AY035037.1_, in POT family
oligopeptide transporter, putative / similar to oligopeptide transporter 1-1 GI:510238 from [Arabidopsis thaliana], in POT family
At1g22540 Link to TAIR Link to Aramemnon (571aa) 12 TMS, N-term is IN oligopeptide transporter, putative / similar to oligopeptide transporter 1-1 GI:510238 from [Arabidopsis thaliana], in POT family
www.cbs.umn.edu /arabidopsis/atprotdb2/famPOT.htm   (1397 words)

  
 Treatment of Focal Cerebral Ischemia With Synthetic Oligopeptide Corresponding to Lectin Domain of Selectin -- Morikawa ...
Treatment of Focal Cerebral Ischemia With Synthetic Oligopeptide Corresponding to Lectin Domain of Selectin -- Morikawa et al.
Treatment of Focal Cerebral Ischemia With Synthetic Oligopeptide Corresponding to Lectin Domain of Selectin
oligopeptide corresponding to the lectin domain of selectin decreases
stroke.ahajournals.org /cgi/content/abstract/27/5/951   (573 words)

  
 [No title]
The OPT family consists of functionally well characterized oligopeptide (3-6 amino acid) transporters in yeast.
Maize Yellow Stripe1, an iron-phytosiderophore uptake transporter, is a member of the oligopeptide transporter (OPT) family.
The YJL212c gene protein (oligopeptide transporter, Opt1p; transports the mammalian pentapeptide, enkephalin, and the tripeptide, glutathione)
www.tcdb.org /tcdb/tcfamilybrowse.php?tcname=2.A.67   (574 words)

  
 The Molecular Physiology of Sodium- and Proton-Coupled Solute Transporters -- Steel and Hediger 13 (3): 123 -- ...
Dietary protein is hydrolyzed by membrane-bound peptidases to form oligopeptides that are transported into enterocytes by H
This process is driven by the proton-motive force, which is generated by apical membrane Na exchanger and basolateral Na ATPase.
Stoichiometry and pH dependence of the rabbit proton-dependent oligopeptide transporter PepT1.
physiologyonline.physiology.org /cgi/content/full/13/3/123   (3116 words)

  
 [No title]
Two oligopeptide transporters from Caenorhabditis elegans: molecular cloning and functional expression.
Characterization of an oligopeptide transporter in renal lysosomes.
High affinity oligopeptide transporter, CPTA (transports di-, tri- and tetra peptides with low specificity.
www.tcdb.org /tcdb/tcfamilybrowse.php?tcname=2.A.17   (617 words)

  
 Interactions of the Dipeptide Ester Prodrugs of Acyclovir with the Intestinal Oligopeptide Transporter: Competitive ...
Interactions of the Dipeptide Ester Prodrugs of Acyclovir with the Intestinal Oligopeptide Transporter: Competitive Inhibition of Glycylsarcosine Transport in Human Intestinal Cell Line-Caco-2 -- Anand et al.
of the oligopeptide transporter in the absorption of the amino
Anand BS and Mitra AK (2002) Mechanism of corneal permeation of L-valyl ester of acyclovir: targeting the oligopeptide transporter on the rabbit cornea.
jpet.aspetjournals.org /cgi/content/full/304/2/781   (4543 words)

  
 [No title]
Length=45 Percent_id=33.3333333333333 Query= oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [Vibrio parahaemolyticus RIMD 2210633] Accesion= gi28901594refNP_801249.1
Length=28 Percent_id=39.2857142857143 Query= oligopeptide ABC transporter, permease protein [Vibrio parahaemolyticus RIMD 2210633] Accesion= gi28898863refNP_798468.1
Length=226 Percent_id=35.8407079646018 Query= oligopeptide ABC transporter, ATP-binding protein [Vibrio parahaemolyticus RIMD 2210633] Accesion= gi28898862refNP_798467.1
www.binf.ku.dk /~tlitman/myco/parsedRep3   (13055 words)

  
 AtOPT3, a Member of the Oligopeptide Transporter Family, Is Essential for Embryo Development in Arabidopsis -- Stacey ...
AtOPT3, a Member of the Oligopeptide Transporter Family, Is Essential for Embryo Development in Arabidopsis -- Stacey et al.
loss-of-function mutation in one of the Arabidopsis oligopeptide
Higgins, C.F., and Payne, J.W. Peptide transport by germinating barley embryo: Uptake of physiological di- and oligopeptides.
www.plantcell.org /cgi/content/full/14/11/2799   (6160 words)

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