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Ophthalmoplegia | Principal Health News Ophthalmoplegia is a paralysis or weakness of one or more of the muscles that control eye movement. Diseases associated with ophthalmoplegia are ocular myopathy, which affects muscles, and internuclear ophthalmoplegia, a disorder caused by multiple sclerosis, a disease which affects nerves. Because ophthalmoplegia is caused by another, underlying disease, it is often associated with other neurologic symptoms, including limb weakness, lack of coordination, and numbness. www.principalhealthnews.com /topic/topic100587229   (1174 words)

Ophthalmoplegia Encyclopedia of Medicine - Find Articles   (Site not responding. Last check: 2007-10-08) In this form of ophthalmoplegia, the patient may experience weakness of the face, the muscles involved in swallowing, the neck, or the limbs. Some of the progressive external ophthalmoplegia syndromes are unusual in that inheritance is controlled by DNA in the mitochondria. Internuclear ophthalmoplegia in multiple sclerosis is caused by damage to a bundle of fibers in the brainstem called the medial longitudinal fasciculus. www.findarticles.com /p/articles/mi_g2601/is_0009/ai_2601000985   (1020 words)

PEO1 - progressive external ophthalmoplegia 1 The case of a 66-year-old woman with progressive external ophthalmoplegia and involvement of the proximal muscles of the upper and lower limbs is described. The purpose of this report is to alert the ophthalmologist and neurologist to the fact that intermittent ocular symptoms may herald the onset of chronic progressive external ophthalmoplegia and therefore resemble the weakness produced by myasthenia gravis. Three groups of cases could be identified clinically: a combination of progressive external ophthalmoplegia and weakness of the limbs induced or increased by exertion (55%); such limb weakness alone (18%); and those with clinical features, such as ataxia, dementia, deafness, involuntary movements and seizures, predominantly or exclusively arising from the CNS (27%). www.ihop-net.org /UniPub/iHOP/gi/101078.html   (5469 words)

Review of Ophthalmology Ophthalmoplegia may be unilateral or bilateral, and, as with ptosis, may be present as an isolated sign of myasthenia. Ophthalmoplegia may also be fatigable and can be tested by having the patient sustain extreme gaze for a minute or so. Mild ophthalmoplegia may not be obvious when testing ductions and versions; ocular misalignment in extreme gaze may be the only sign (See Figure 3). www.revophth.com /index.asp?page=1_219.htm   (1610 words)

Imigraine.Net  B. Todd Troost, M.D. Although granulomatous inflammation of the cavernous sinus may produce a painful ophthalmoplegia, it should be clear that other lesions that involve the structures within the superior orbital fissure or cavernous sinus may also produce painful ophthalmoplegia that is often responsive to systemic corticosteroid therapy. Thomas and Yoss (1970) studied 102 patients with intracranial parasellar lesions and found that neither the mode of onset of symptoms nor the sequence of evolution or pattern of the neurologic deficit is characteristic of the etiology of the underlying lesion, whether it is neoplastic, aneurysmal, or inflammatory. Thus, in addition to a complete neuroradiologic evaluation, patients with painful ophthalmoplegia may require a serologic test for syphilis (STS), an erythrocyte sedimentation rate, a temporal artery biopsy, a glucose tolerance test, a rheumatoid factor, and an antinuclear antibody titer. www.imigraine.net /other/tolosa.html   (1555 words)

Bioline International Official Site (site up-dated regularly) Though blindness and ophthalmoplegia are well-known manifestations of raised ICP, flaccid quadriparesis is extremely rare. Ophthalmoplegia with quadriplegia as seen in our cases may resemble Miller Fisher- Guillain- Barre overlap syndrome clinically. In conclusion, we report that the syndrome of visual impairment, ophthalmoplegia and flaccid quadriparesis in patients with ISVT signifies a markedly raised ICP. www.bioline.org.br /request?ni04024   (1833 words)

Ophthalmoplegia - WrongDiagnosis.com The cause of Ophthalmoplegia may be more easily identified if other symptoms exist. When you follow a link to our interactive multiple symptoms page, you will be able to modify your list by adding and removing symptoms thus helping to better research your condition. This information refers to the general prevalence and incidence of these diseases, not to how likely they are to be the actual cause of Ophthalmoplegia. www.wrongdiagnosis.com /sym/ophthalmoplegia.htm   (660 words)

internuclear ophthalmoplegia - multiple sclerosis encyclopaedia   (Site not responding. Last check: 2007-10-08) Internuclear Ophthalmoplegia (INO) is a disorder of eye movements caused by a lesion in an area of the brain called the medial longitudinal fasciculus (MLF). INO is associated with jerky eye movements (nystagmus) in one eye when the other one moves outwards. Multiple sclerosis is the most common cause of internuclear ophthalmoplegia and in MS it is usually unilateral. www.mult-sclerosis.org /internuclearophthalmoplegia.html   (91 words)

eMedicine - Chronic Progressive External Ophthalmoplegia : Article by Tracey A Schmucker, MD   (Site not responding. Last check: 2007-10-08) Ophthalmoplegia generally precedes the development of cardiac conduction disturbances. Carlow TJ, Depper MH, Orrison WW Jr: MR of extraocular muscles in chronic progressive external ophthalmoplegia. Kosmorsky G, Johns DR: Neuro-ophthalmologic manifestations of mitochondrial DNA disorders: chronic progressive external ophthalmoplegia, Kearns-Sayre syndrome, and Leber's hereditary optic neuropathy [published erratum appears in Neurol Clin 1991 May;9(2):xii]. www.emedicine.com /oph/topic510.htm   (1894 words)

Internuclear Ophthalmoplegia: Cranial Nerve Disorders: Merck Manual Home Edition Internuclear ophthalmoplegia is weakness or paralysis of eye movements caused by damage to the nerve fibers connecting collections of nerve cells (centers or nuclei) that give rise to cranial nerves III (oculomotor nerve) and VI (abducens nerve). In internuclear ophthalmoplegia, nerve fibers necessary for the control of horizontal and vertical eye movements—looking from side to side and up and down—are damaged. As in internuclear ophthalmoplegia, vertical eye movements are not affected. www.merck.com /pubs/mmanual_home2/sec06/ch096/ch096b.htm   (241 words)

Muscular Dystrophy, Oculo Gastrointestinal It is inherited as an autosomal recessive trait and its major characteristics are droopy eyelids (ptosis), loss of movement of the external muscles of the eye (external ophthalmoplegia), and a progressive condition in which the intestinal walls are unable to contract normally causing abdominal pain, diarrhea, constipation, and malabsorption of nutrients (progressive intestinal pseudo-obstruction). The main symptoms of this disorder are droopy eyelids, loss of movement of the external muscles of the eye (external ophthalmoplegia), and a progressive condition in which the intestinal walls are unable to contract normally (progressive intestinal pseudo-obstruction). Progressive External Ophthalmoplegia is a rare disorder in which there is drooping of both upper eyelids. hw.healthdialog.com /kbase/nord/nord905.htm   (1325 words)

eMedicine - Chronic Progressive External Ophthalmoplegia : Article by Tracey A Schmucker, MD (via CobWeb/3.1 ...   (Site not responding. Last check: 2007-10-08) Background: Chronic progressive external ophthalmoplegia (CPEO) is a disorder characterized by slowly progressive paralysis of the extraocular muscles. Ptosis usually is the first clinical sign, and ophthalmoplegia may not become apparent for months to years. As the ptosis progresses, the patient may use the frontalis muscle to elevate the eyelids, adopt a chin-up head position, and eventually resort to manual elevation of the eyelids, as ptosis often becomes complete. www.emedicine.com.cob-web.org:8888 /oph/topic510.htm   (1896 words)

Elevated visual motion detection thresholds in adults with acquired ophthalmoplegia -- Acheson et al. 85 (12): 1447 -- ... Five patients (two males and three females) with ophthalmoplegia were included in the study. The neural substrate for this evolution of symptoms in the presence of continuing ophthalmoplegia has not been fully elucidated. Visual motion thresholds were elevated in all patients with ophthalmoplegia regardless of symptoms or aetiology. bjo.bmj.com /cgi/content/full/85/12/1447   (1350 words)

Bioline International Official Site (site up-dated regularly) Spector et al[2] reported that phenytoin could induce total external ophthalmoplegia irrespective of oral or intravenous administration. The majority of the reported cases of phenytoin-induced ophthalmoplegia recovered completely over a variable period with normalization of the phenytoin level. The present case is unique; in spite of the drug toxicity the patient was alert and had bilateral external ophthalmoplegia with loss of oculocephalic and oculovestibular reflexes. www.bioline.org.br /request?ni04126   (790 words)

Chronic asymmetric progressive external ophthalmoplegia with right facial weakness: a unique presentation of ... Chronic asymmetric progressive external ophthalmoplegia with right facial weakness: a unique presentation of mitochondrial myopathy -- Sharma et al. eye and she was felt to have a right internuclear ophthalmoplegia. were in the differential diagnoses for this progressive ophthalmoplegia. jnnp.bmj.com /cgi/content/full/73/1/95   (646 words)

Supranuclear ophthalmoplegia Patients who have this problem may have a degenerative disorder that affects the way the brain controls movement called progressive supranuclear palsy. In other cases, a brain injury (such as stroke) can result in various types of supranuclear ophthalmoplegia. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. www.mercydesmoines.org /ADAM/Encyclopedia/ency/001624.asp   (219 words)

NEJM -- Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome We investigated the correlations of deletions of mitochondrial DNA in skeletal muscle with clinical manifestations of mitochondrial myopathies, a group of disorders defined either by biochemical abnormalities of mitochondria or by morphologic changes causing a ragged red appearance of the muscle fibers histochemically. Deletions were found in the mitochondrial DNA of 32 patients, all of whom had progressive external ophthalmoplegia. We conclude that deletions of muscle mitochondrial DNA are associated with ophthalmoplegia and may result in impaired mitochondrial function. content.nejm.org /cgi/content/abstract/320/20/1293   (1255 words)

Bickerstaff's brainstem encephalitis: clinical features of 62 cases and a subgroup associated with Guillain-Barre ... of ophthalmoplegia and ataxia in BBE and FS are identical. Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I. Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain–Barré syndrome: clinical and immunohistochemical studies. The nosological position of the ophthalmoplegia, ataxia and areflexia syndrome: ‘the spectrum hypothesis’. brain.oxfordjournals.org /cgi/content/full/126/10/2279   (4799 words)

EyeRounds.org: Chronic Progressive External Ophthalmoplegia - Kearns-Sayre Syndrome Involutional ptosis is associated with good levator function and high upper lid crease and occurs in the elderly due to dysfunction or dehiscence (which is hardly never seen at the time of surgery) of the levator muscle. If the patient does not fit one of these two most common causes of ptosis, then the clinician needs to consider one of the less common causes of ptosis.Clinicians who are “lumpers” would categorize this patient as having Chronic Progressive External Ophthalmoplegia (CPEO) with varying risk of developing other organ system involvement. Those who are “splitters” would say that he has Kearns-Sayre syndrome, a subset of CPEO that places him at high risk for sudden cardiac death. webeye.ophth.uiowa.edu /eyeforum/cases/case24.htm   (708 words)

Supranuclear ophthalmoplegia   (Site not responding. Last check: 2007-10-08) Supranuclear ophthalmoplegia is the inability to voluntarily move the eyes in all directions. This disorder occurs because the brain is sending and receiving faulty information through the nerves that control eye movement. Patients who have this problem may have progressive supranuclear palsy, a disorder that affects the way the brain controls movement called. www.shands.org /health/information/001624.htm   (162 words)

Journal of Pediatric Ophthalmology and Strabismus - Ocular Myasthenia Presenting as Progressive External Ophthalmoplegia Ocular myasthenia is a form of myasthenia gravis clinically involving only the levator palpebrae superioris, the orbicularis oculi and the extraocular muscles. Ptosis and ophthalmoplegia, both unilateral and bilateral, constitute the only signs in about 20% cases; in about 70% cases, ocular symptoms mark the onset of generalized myasthenia gravis. We report 3 unusual cases of ocular myathenia with systemic symptoms, who presented with progressive external ophthalmoplegia, ptosis, and documented thymus hyperplasia, as well as discuss different diagnostic techniques and treatment modalities for the evaluation of the same. www.journalofpediatricophthalmology.com /showAbst.asp?thing=4730   (148 words)

Ophthalmoparesis - Wikipedia, the free encyclopedia It refers to paralysis of the extraocular muscles which are responsible for eye movements. Ophthalmoparesis can involve any or all of the extraocular muscles, which include the superior recti, inferior recti, medial recti, lateral recti, inferior oblique and superior oblique muscles. White matter tracts in the brainstem, as in internuclear ophthalmoplegia, an occasional finding in multiple sclerosis. en.wikipedia.org /wiki/Ophthalmoparesis   (268 words)

X linked severe mental retardation, craniofacial dysmorphology, epilepsy, ophthalmoplegia, and cerebellar atrophy in a ... X linked severe mental retardation, craniofacial dysmorphology, epilepsy, ophthalmoplegia, and cerebellar atrophy in a large South African kindred is localised to Xq24-q27 -- Christianson et al. X linked severe mental retardation, craniofacial dysmorphology, epilepsy, ophthalmoplegia, and cerebellar atrophy in a large South African kindred is localised to Xq24-q27 ophthalmoplegia, atrophy of the cerebellum and brain stem, and jmg.bmjjournals.com /cgi/content/full/36/10/759   (3240 words)

Arch Neurol -- Posttraumatic Bilateral Internuclear Ophthalmoplegia With Exotropia, March 2004, Jung and Park 61 (3): ...   (Site not responding. Last check: 2007-10-08) Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. Bilateral internuclear ophthalmoplegia with exotropia in primary position. T1-weighted (A) and gradient-echo (B) magnetic resonance images showing a discrete subacute hemorrhage extending ventrally from the floor to fourth ventricle at the upper pontine level. archneur.ama-assn.org /cgi/content/extract/61/3/429   (111 words)

Chronic Progressive External Ophthalmoplegia: MR Spectroscopy and MR Diffusion Studies in the Brain -- Heidenreich et ... Chronic Progressive External Ophthalmoplegia: MR Spectroscopy and MR Diffusion Studies in the Brain -- Heidenreich et al. ptosis and external ophthalmoplegia as hallmarks of the disease. Spongiform encephalopathy with chronic progressive external ophthalmoplegia: central ophthalmoplegia mimicking ocular myopathy. www.ajronline.org /cgi/content/full/187/3/820   (2546 words)

InterNuclear Ophthalmoplegia (INO) Abstracts Abduction Paresis with rostral Pontine and/or Mesencephalic lesions: PseudoAbducens Palsy and its relation to the so-called posterior InterNuclear Ophthalmoplegia of Lutz InterNuclear Ophthalmoplegia (INO) is a Gaze Disorder characteristic of lesions involving the Medial Longitudinal Fasciculus (MLF). The site of lesions responsible for Horizontal Gaze Palsy and various types of InterNuclear Ophthalmoplegia (INO) was established by identifying the common areas where the abnormal MRI signals from patients with a given Ocular-Motor Disorder overlapped. members.tripod.com /~ThJuland/ino.html   (1602 words)

Ophthalmoplegia - Social Security Disability This is very rare, and in order to qualify the claimant must have Ophthalmoplegia in both eyes. Ophthalmoplegia is a weakness of one or more of the muscles that control eye movement. To be severe enough you must have opthalmoplegia in both eyes. www.socialsecurityhome.com /ophthalmoplegia.htm   (87 words)

Recurrent anti-GQ1b IgG antibody syndrome showing different phenotypes in different periods -- Hamaguchi et al. 74 (9): ... acute onset of ophthalmoplegia, ataxia, and areflexia at age ophthalmoplegia from age 17; and third, acute onset of complete Isolated internal ophthalmoplegia associated with IgG anti-GQ1b antibody. jnnp.bmjjournals.com /cgi/content/full/74/9/1350   (778 words)

Paraneoplastic ophthalmoplegia and subacute motor axonal neuropathy associated with anti-GQ1b antibodies in a patient ... Paraneoplastic ophthalmoplegia and subacute motor axonal neuropathy associated with anti-GQ1b antibodies in a patient with malignant melanoma -- Kloos et al. Paraneoplastic ophthalmoplegia and subacute motor axonal neuropathy associated with anti-GQ1b antibodies in a patient with malignant melanoma Co-localisation is confirmed in yellow (panel C) by double exposure from the superimposition of red and green. jnnp.bmjjournals.com /cgi/content/full/74/4/507   (1524 words)

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