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Topic: Optic atrophy

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	HerbChina2000.com - Herbal Remedies - Optic atrophy
		Optic atrophy may also be referred to as optic nerve head pallor because of the pale appearance of the optic nerve head as seen at the back of the eye.
		In primary optic atrophy (usually due to pathology distant from the nerve head), the disk is white or grayish with sharp edges.
		In secondary optic atrophy (usually due to pathology at the nerve head), the disk is dirty-white with irregular, indistinct margins and is covered by glial tissue that conceals the lamina cribrosa.
	www.herbchina2000.com /therapies/XPA.shtml (1059 words)

	Leber hereditary optic neuropathy -- Man et al. 39 (3): 162 -- Journal of Medical Genetics
		Leber hereditary optic neuropathy (LHON) is a mitochondrial
		Optic nerve sheath distention in Leber's optic neuropathy and the significance of the "Wallace mutation".
		Leber hereditary optic neuropathy: mitochondrial mutations and degeneration of the optic nerve.
	jmg.bmjjournals.com /cgi/content/full/39/3/162 (6121 words)

	THE MERCK MANUAL, Sec. 8, Ch. 101, Optic Nerve And Optic Pathway Disorders
		In primary optic atrophy (usually due to pathology distant from the nerve head), the disk is white or grayish with sharp edges.
		In secondary optic atrophy (usually due to pathology at the nerve head), the disk is dirty-white with irregular, indistinct margins and is covered by glial tissue that conceals the lamina cribrosa.
		Optic atrophy is a sign of chronic optic nerve disease and is not a diagnosis in itself; its presence demands search for a cause.
	www.merck.com /mrkshared/mmanual/section8/chapter101/101e.jsp (154 words)

	[No title]
		Optic atrophy, is defined as: "atrophy of the optic disc resulting from degeneration of the nerve fibers of the optic nerve and optic disc" (Dorlands 28th edition).
		However, in 30 (48.4%) of the residents with mental retardation and optic atrophy, the etiology of the brain disorder was unknown.
		Furthermore, just because the etiology of optic atrophy is known in other patients it is still possible that they are at risk for hypothalamic pituitary abnormalities, due to the relationship, anatomically, of the optic nerve, optic chiasm, and optic tracts to other structures in the brain.
	www2.umdnj.edu /forumweb/optic.htm (1238 words)

	Optic atrophy
		Optic atrophy can be defined as damage to the optic nerve resulting in a degeneration or destruction of the optic nerve.
		Optic neuritis is an inflammation of the optic nerve.
		Nutritional optic neuropathy may be caused by deficiencies of protein, or of the B vitamins and folate, associated with starvation, malabsorption, or alcoholism.
	www.healthatoz.com /healthatoz/Atoz/ency/optic_atrophy.jsp (1107 words)

	[No title]
		Optic neuritis with residual optic atrophy of the right eye diagnosed after service cannot be dissociated from complaints of blurred vision shown in service.
		Service connection for optic atrophy was predicated upon a diagnosis of multiple sclerosis, found on a VA examination of November 1986.
		Although retrobulbar optic neuritis was a working diagnosis at one point, the relationship to headaches, minimal afferent pupillary defect and macular pigmentary changes raised a variety of hereditary possibilities.
	www.va.gov /vetapp/files3/9420190.txt (1924 words)

	The Optic Nerve
		The optic nerve (also known as cranial nerve II) is a continuation of the axons of the ganglion cells in the retina.
		Optic neuropathy is divided into anterior, which causes a pale edema of the optic disk, and posterior, in which the optic disk is not swollen and the abnormality occurs between the eyeball and the optic chiasm.
		Ischemic anterior optic neuropathy usually causes a loss of vision that may be sudden or occur over several days; whereas, ischemic posterior optic neuropathy is uncommon, and the diagnosis depends largely upon exclusion of other causes, chiefly stroke and brain tumor.
	www.tedmontgomery.com /the_eye/optcnrve.html (1666 words)

	Leber's Optic Atrophy - Patient UK
		LHON, Leber's Optic Atrophy, Leber's Optic Neuropathy, Hereditary Optic Neuroretinopathy
		Leber's hereditary optic atrophy is a disease of mitochondria.
		Optic atrophy develops and clinical investigations are unhelpful in distinguishing it from other causes.
	www.patient.co.uk /showdoc/40001406 (1095 words)

	eMedicine - Optic Neuropathy, Compressive : Article by Talmadge (Ted) Cooper, MD (Site not responding. Last check: 2007-11-05)
		The triad of optic disc swelling followed by optic atrophy, optociliary shunt veins (optochoroidal collaterals), and progressive visual loss commonly is reported in compressive lesions of the orbital and intracanalicular optic nerve.
		Optic canal decompression for tumors in the intracanalicular area is extremely risky, and not uncommonly results in the loss of any remaining vision, unless the tumor has a large exophytic component.
		Optic neuritis usually presents with acute or subacute visual loss in a patient younger than 50 years and frequently is associated with pain on eye movement.
	www.emedicine.com /oph/topic167.htm (2670 words)

	MediZine Healthy Living (Site not responding. Last check: 2007-11-05)
		Optic nerve atrophy involves tissue death of the nerve that carries the information of vision from the eye to the brain.
		The optic nerve can also be damaged by shock, various toxic substances, radiation, and trauma.
		There are also several rare forms of hereditary optic nerve atrophy that affect children and young adults.
	www.medizine.com /encyclopedia/Ency.aspx?qu=001622.htm (308 words)

	Optic Atrophy \| Principal Health News
		Using a hand-held instrument called an ophthalmoscope, the doctor can see the optic nerve head (optic disc) which is the part of the optic nerve that enters at the back of the eyeball.
		The most common toxic optic neuropathy is known as tobacco-alcohol amblyopia, thought to be caused by exposure to cyanide from tobacco smoking, and by low levels of vitamin B
		If the cause of toxic or nutritional deficiency optic neuropathy can be found and treated early, such as stopping smoking and taking vitamins in tobacco-alcohol amblyopia, vision generally returns to near normal over several months' time.
	www.principalhealthnews.com /topic/topic100587231 (1101 words)

	Optic atrophy (Site not responding. Last check: 2007-11-05)
		Optic atrophies (OA) refer to a specific group of hereditary optic neuropathies in which the cause of the optic nerve dysfunction is inherited either in an autosomal dominant or autosomal recessive pattern.
		In the pure congenital AROA, optic atrophy is never associated with neurological disorder and visual impairment is severe.
		Leber's hereditary optic neuropathy (LHON) refers to an optic nerve dysfunction due to mutations in the mitochondrial DNA (mtDNA) and is transmitted in a non-mendelian or maternal pattern.
	orphanet.infobiogen.fr /static/GB/optic_atrophy.html (466 words)

	Dr. Koop - Optic nerve atrophy
		Optic nerve atrophy involves tissue death of the nerve that carries the information of vision from the eye to the brain.
		The optic nerve can also be damaged by shock, various toxic substances, radiation, and trauma.
		There are also several rare forms of hereditary optic nerve atrophy that affect children and young adults.
	www.drkoop.com /ency/93/001622.html (310 words)

	Optic Atrophy: Definition, Symptoms, and Treatment - Kellogg Eye Center
		Optic atrophy means the loss of some (resulting in little visual change) or most (resulting in severe visual loss) of the nerve fibers in the optic nerve.
		Optic atrophy can occur in people where the optic nerve or nerves did not develop properly.
		The optic nerve enters the back of the eye where it appears as a small disc, which your ophthalmologist can examine by looking through the pupil of your eye with a special instrument called an ophthalmoscope.
	www.kellogg.umich.edu /patientcare/conditions/optic.atrophy.html (373 words)

	Fact Sheet Optic Nerve Atrophy
		TM Optic Nerve Atrophy (ONA) is a permanent visual impairment caused by damage to the optic nerve.
		The optic nerve, when examined with an ophthalmoscope, has a gray-white appearance, which may not be apparent for 4-6 weeks from time of optic nerve injury.
		Optic atrophy which occurs in both eyes from time of birth (bilateral and congenital) may cause rhythmic, involuntary eye movements (nystagmus).
	www.blindbabies.org /factsheet_ona.htm (988 words)

	Optic nerve problems
		The optic nerve can be affected due to birth anomalies like Coloboma.
		This is the swelling of the optic nerve due to raised intracranial pressure, i.e.
		Optic Atrophy means loss of function of the Optic nerve.
	members.tripod.com /manisha_b/Optic_Nerve/OpticNProblems.htm (272 words)

	Bst mutation in mouse (OPA1)
		Recently, we have identified a striking abnormality in optic nerves of mice that are heterozygous for the spontaneous mutation belly spot and tail (Bst).
		This neurological phenotype is associated with a unilateral or bilateral atrophy of the optic nerves.
		As in humans with OPA1, the severity of the atrophy of the optic nerves is highly variable—ranging from a slight reduction in the number of ganglion cell axons in one optic nerve to a complete elimination of both optic nerves.
	www.nervenet.org /papers/Bst2.html (1783 words)

	Optic Atrophy
		Optic atrophy is a condition that affects the optic nerve, which carries impulses from the eye to the brain.
		Optic atrophy is not a disease, but rather a sign of a potentially more serious condition.
		The optic nerve is composed of nerve fibers that transmit impulses to the brain.
	www.clevelandclinic.org /health/health-info/docs/3800/3864.asp?index=12326 (541 words)

	Optic nerve atrophy - UMMC
		Once it has occurred, damage from optic nerve atrophy cannot be reversed.
		Vision lost to optic nerve atrophy cannot be recovered.
		Patients with optic nerve atrophy will be closely monitored by an ophthalmologist with experience in neuro-ophthalmology.
	www.umm.edu /ency/article/optic_nerve_atrophy_treatment_001622trt.htm (165 words)

	Optic Atrophy (Site not responding. Last check: 2007-11-05)
		Simply defined, this is a loss of function of the optic nerve with resulting gliosis and a decrease or loss of capillaries and axonal tissue within the nerve.
		The type of optic atrophy depends on the pathogenetic factors involved; ascending damage from within the eye (glaucoma, optic neuritis, papilledema, and many primary lesions of the retina-choroid), descending from damage to the optic nerve or brain (trauma, hydrocephalus, neoplasm, demyelinating diseases), or due to congenital defect (Leber's optic atrophy).
		Histologically, the myelin sheaths and axons degenerate, resulting in loss of substance of the optic nerve, causing expansion of the subarachnoid space (and causing the dura to appear redundant).
	insight.med.utah.edu /opatharch/onerve/optic_atrophy.htm (207 words)

	► Optic nerve atrophy
		Atrophy (tissue death) of the nerve that carries the information of vision from the eye to the brain.
		The optic nerve may be damaged by shock, various toxic substances, radiation, and trauma.
		Optic nerve atrophy may be caused by disease of the brain, such as multiple sclerosis, brain tumor, and stroke.
	www.umm.edu /ency/article/001622.htm (197 words)

	Optic disc morphology of patients with OPA1 autosomal dominant optic atrophy -- Votruba et al. 87 (1): 48 -- British ...
		of a grey pigmentary crescent, and peripapillary atrophy.
		Infantile optic atrophy with dominant mode of inheritance: a clinical and genetic study of 19 Danish families.
		Histopathology of eye, optic nerve and brain in a case of dominant optic atrophy.
	bjo.bmjjournals.com /cgi/content/full/87/1/48 (3160 words)

	Leber's Optic Atrophy
		Leber’s Optic Atrophy is a rare inherited disorder of the eye that is characterized by the slow, painless, progressive loss of vision in one eye.
		Leber's Optic Atrophy is marked by slow degeneration of cells in the retina (the part of the eye opposite the pupil).
		Leber's Optic Atrophy is a rare disorder that is inherited from the mother as changes (mutation[s]) in the unique genetic material found within the DNA of mitochondria (mtDNA).
	hw.healthdialog.com /kbase/nord/nord534.htm (1239 words)

	Optic atrophy and chiasm
		Optic atrophy means disc pallor, from loss of axons, glial proliferation and decreased vascularity that follows many pathological processes, e.g.
		Optic atrophy is described as consecutive or secondary when it follows papilloedema of any cause.
		Optic tract lesions (which are rare) cause field defects which are homonymous, hemianopic and often incomplete and incongruous.
	www.depression-guide.com /optic-atrophy.htm (185 words)

	Optic Atrophy (Site not responding. Last check: 2007-11-05)
		Optic Atrophy A Good Patient Summary Article on optic atrophy: Dysfunction of the optic nerve; may be congenital or acquired.
		The milder form is autosomal dominant and has a gradual onset of deterioration in childhood but little progression thereafter; the more severe form is autosomal recessive and is present at birth or within 2 years; this form is accompanied by nystagmus.
		Pale optic disk and loss of pupillary reaction are usually proportionate to the visual loss.
	www.lowvision.org /optic_atrophy.htm (118 words)

	Optic atrophy (Site not responding. Last check: 2007-11-05)
		Visual loss as a result of pressure against the optic nerve may be restored if the cause is identified and treated early.
		Optic atrophy secondary to vascular, traumatic, degenerative, and some toxic causes has a negative prognosis.
		Optic nerve hypoplasia is an undeveloped optic nerve due to a neurological insult early in the prenatal developmental period; the optic nerve has started to develop, but regresses.
	www.spedex.com /resource/documents/veb/optic_atrophy.html (384 words)

	ONA
		Optic Nerve Atrophy (ONA) is a permanent visual impairment caused by damage to the optic nerve.
		The optic nerve functions like a cable carrying information from the eye to be processed by the brain.
		The optic nerve is comprised of over a million small nerve fibers (axons).
	www.e-advisor.us /ona_fact_sheet.htm (1006 words)

	MedlinePlus Medical Encyclopedia: Optic nerve atrophy
		Optic nerve atrophy can be readily detected on complete examination of the eyes.
		Once it has occurred, damage from optic nerve atrophy cannot be reversed.
		Vision lost to optic nerve atrophy cannot be recovered.
	www.nlm.nih.gov /medlineplus/ency/article/001622.htm (490 words)

	AllRefer Health - Optic Nerve Atrophy (Second Cranial Nerve Atrophy)
		AllRefer Health - Optic Nerve Atrophy (Second Cranial Nerve Atrophy)
		In addition, the condition can be caused by diseases of the brain and central nervous system, such as multiple sclerosis, brain tumor, and stroke.
		Optic Nerve Atrophy Overview, Causes, and Risk Factors
	health.allrefer.com /health/optic-nerve-atrophy-info.html (354 words)

	Developmental Expression Profile of the Optic Atrophy Gene Product: OPA1 Is Not Localized Exclusively in the Mammalian ...
		was observed in the myelinated region of the optic nerve, and
		Kjer P. Infantile optic atrophy with dominant mode of inheritance: a clinical and genetic study of 19 Danish families.
		A frameshift mutation in exon 28 of the OPA1 gene explains the high prevalence of dominant optic atrophy in the Danish population: evidence for a founder effect.
	www.iovs.org /cgi/content/full/45/6/1667 (5321 words)

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