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Topic: Optical coherence tomography

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Optical coherence tomography - Wikipedia, the free encyclopedia Optical coherence tomography (OCT) is an interferometric, non-invasive optical tomographic imaging technique offering millimeter penetration (approximately 2--3 mm in tissue) with sub-micrometre axial and lateral resolution. The axial and lateral resolutions of OCT are decoupled from one another; the former being an equivalent to the coherence length of the light source and the latter being a function of the optics. The optical carrier is due to the Doppler effect resulting from scanning one arm of the interferometer, and the frequency of this modulation is controlled by the speed of scanning. en.wikipedia.org /wiki/Optical_coherence_tomography   (2162 words)

LightLab Imaging Technology Optical Coherence Tomography (OCT) is a promising new class of diagnostic medical imaging technology that utilizes advanced photonics and fiber optics to obtain images and tissue characterization on a scale never before possible within the human body. OCT imaging can be performed over approximately the same distance of a biopsy at high resolution and in real time making the most attractive applications for OCT those where conventional biopsies cannot be performed or are ineffective. Simply put, OCT combines the principles of ultrasound with the imaging performance of a microscope and a form factor that is familiar to clinicians. www.lightlabimaging.com /oct.html   (306 words)

Optical Coherence Tomography Optical coherence tomography is the optical analog of ultrasound, and it performs cross-sectional imaging by measuring optical echoes. The result is a two-dimensional data set, which represents the optical reflection or backscattering in a cross-sectional plane through the material or tissue. OCT was first demonstrated in 1991.(1) Imaging was performed in vitro in the human retina and in atherosclerotic plaque as examples of imaging in transparent, weakly scattering media as well as in highly scattering media. www.dekker.com /sdek/71068315-20810899/abstract~db=enc~content=a713548195~words=   (425 words)

Optical Coherence Tomography The accuracy of OCT distance measurements is limited by the scattering, absorption, dispersion, and birefringence of the tissue, as well as the lack of high-accuracy data on the refractive indices of various human tissues. OCT has applications ranging from early detection of glaucoma to measuring the morphology of the arterial plaques that may be responsible for 70 % of heart attacks. We are interested in applying OCT to measurements of tissue dispersion and absorption for tissue identification and early disease diagnosis. www4.nationalacademies.org /pga/rap.nsf/ByTitle/50.81.52.B5890?OpenDocument   (325 words)

Ultrahigh-resolution ophthalmic optical coherence tomography - Nature Medicine Topography of diabetic macular edema with optical coherence tomography. Layers that consist of nerve fibers or plexiform layers are optically backscattering, whereas nuclear layers are weakly backscattering. Examples of a segmented OCT image of the fovea (a), the measured thicknesses of the various retinal layers (b), and a measurement of the retinal layers along the papillomacular axis (c) are shown in Fig. www.nature.com /cgi-taf/DynaPage.taf?file=/nm/journal/v7/n4/full/nm0401_502.html   (4034 words)

Optical Coherence Tomography Optical Coherence Tomography, or OCT, is a laser-based, noncontact, noninvasive imaging technique that is capable of obtaining high resolution images of the retina and its components. OCT is analogous to ultrasound imaging except that light rather than sound waves are used, resulting in a much higher resolution of approximately 10µm in the retina. OCT has been shown to be clinically useful for imaging and directly visualizing selected macular diseases including macular holes, macular edema, age-related macular degeneration, central serous chorioretinopathy, epiretinal membranes, schisis cavities associated with optic disc pits, and retinal inflammatory diseases. www.bouldereyesurgeons.com /retina8.htm   (196 words)

Optical Coherence Tomography - OCT Similar to retinal CT scans of internal organs, OCT uses the optical backscattering of light to rapidly scan the eye and describe a pixel representation of the anatomic layers within the retina. OCT, the first instrument to allow doctors to see cross-sectional images of the retina, is revolutionizing the early detection and treatment of eye conditions such as macular holes, pre-retinal membranes, macular swelling and even optic nerve damage. OCT is a new, non-invasive technology used for imaging the retina, the multi-layered sensory tissue lining the back of the eye. www.suncoastretina.com /Procedures/OCT.htm   (498 words)

Fundus Photograph Reading Center - Optical Coherence Tomography Protocol Optical coherence tomography (OCT) is an imaging technique that produces high resolution cross sectional images of optical reflectivity (1,2). It is based on the principle of low-coherence interferometry where distance information concerning various ocular structures is extracted from time delays of reflected signals. In OCT, light waves emitted by a superluminescent diode operating at 840 nm and between 200 uw and 1 mw are used to determine the images. eyephoto.ophth.wisc.edu /ResearchAreas/oct/oct1.htm   (580 words)

Characterization of dentin by optical coherence tomography Objectives: The aim of this study was to construct a polarization sensitive optical coherence tomography system (PS-OCT) and to compare its imaging characteristics to intensity images obtained with conventional OCT. Methods: Transverse sections were made of five extracted teeth near the dentin-enamel junction. Optical Coherence Tomography (OCT) may play an important role in imaging interglobular dentin. The sections were imaged with conventional OCT using a 2.2 mW superluminescent diode with a center wavelength of 1300 nm and a spectral bandwidth of 40 nm as a low coherent source. iadr.confex.com /iadr/2004Hawaii/techprogram/abstract_45868.htm   (298 words)

OSL: Optical Coherence Tomography Optical coherence tomography, or OCT, was developed in the late 1980s and introduced in 1991 as a laser-based, noninvasive cross-sectional imaging technique that utilizes low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a manner similar to ultrasonography but with higher resolution. Optical coherence tomography systems are now in use throughout the world, making available diagnostic information previously difficult or impossible to obtain, for a variety of retinal and glaucoma applications, as well as high-resolution imaging for corneal and refractive surgery. In addition to numerous and growing ophthalmic applications, OCT is also widely employed in other biomedical specialties including dermatology, gastroenterology, gynecology, and cardiology. www.slackinc.com /EYE/os/stor0500/6editorial.htm   (321 words)

Optical coherence tomography (OCT) A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively. omlc.ogi.edu /pubs/abs/huang91.html   (95 words)

Optical Coherence Tomography The result is a two-dimensional representation of the optical backscattering of the tissue's cross-section, which displays as a gray-scale or false-color image. OCT produces images that are two- or three-dimensional data sets, representing differences in optical backscattering. OCT is based on fiber optics and often uses a compact diode light source only millimeters in size. www.afrlhorizons.com /Briefs/Mar03/OSR0209.html   (967 words)

Optical Coherence Tomography Clinical Database - New York Eye & Ear Infirmary Optical coherence tomography (OCT) is a new, noninvasive, noncontact, transpupillary imaging technology which can image retinal structures in vivo with a resolution of 10 to 17 microns. Cross-sectional images of the retina are produced using the optical backscattering of light in a fashion analogous to B- scan ultrasonography. The appearance of a variety of posterior segment pathologies using OCT has been described. www.nyee.edu /page_deliv.html?page_no=118&origin=95   (135 words)

Optical Coherence Tomography Optical Coherence Tomography (OCT) is a new noninvasive optical diagnostic technique that provides depth-resolved images of tissues with resolution of about 2-10 µm at depths of up to several mm. The basic principle of the OCT is to detect backscattered photons from a tissue of interest within a coherence length of the source by using a two-beam interferometer. OCT imaging is somewhat analogous to ultrasound B-mode imaging except that it uses light, not sound. www.egr.uh.edu /bol/OCT.html   (330 words)

Optical Coherence Tomography (OCT) Optical Coherence Tomography, or OCT, is a noncontact, noninvasive imaging technique used to obtain high resolution cross-sectional images of the retina. In addition, OCT has the capability of measuring the retinal nerve fiber layer thickness in glaucoma and other diseases of the optic nerve. It has been shown to be clinically useful for imaging selected macular diseases including macular holes, macular edema, age-related macular degeneration, central serous chorioretinopathy, epiretinal membranes, schisis cavities associated with optic disc pits, and retinal inflammatory diseases. www.eye.com.ph /oct.htm   (355 words)

Contrast agents enhance optical coherence tomography Similar in operation to ultrasound, optical coherence tomography (OCT) is an optical technique that allows high-resolution imaging of tissue. "OCT is a relatively new technology that is just beginning to be used in the clinical setting," said Stephen Boppart, a professor of electrical and computer engineering and of bioengineering. By enhancing contrast locally, the microspheres would permit OCT to be used both for early detection and for advanced tumor diagnostics. www.news.uiuc.edu /scitips/01/11tumor.html   (473 words)

Optical Coherence Tomography The thickness is measured with Optical Coherence Tomography, OCT. The measurement data does not immediately give the thickness. To use OCT measurements for glaucoma diagnostics, it would be of medical importance to develop models for the thickness of the RNFL, and in particular its dependence on the density of the ganglion cells, from which the nerve fibres emerge. Another way of drawing information from OCT measurements of the RNFL thickness is to use machine learning techniques for determining whether a thickness profile comes from a healthy or a glaucomatous eye. www.maths.lth.se /matematiklth/vision/research2004/node16.html   (394 words)

Bascom Palmer Eye Institute - Patients & Benefactors Optical Coherence Tomography (OCT, Humphrey Instruments, Inc., San Leandro, CA) is a laser imaging technology with a resolution of 10-17 microns. Cross-sectional images of the retina are produced using the optical backscattering of light in a manner analogous to B-scan ultrasonography. Measurements with the Lab OCT of the optical properties of accurately resolved retinal layers in experimental tissue preparations will increase our understanding of OCT3 images from glaucoma patients. www.bpei.med.miami.edu /site/current/current_patben.asp   (5920 words)

Polarisation-sensitive optical coherence tomography of Collagen Polarization-sensitive optical coherence tomography combines polarimetry with low coherence reflectometry to provide high-resolution optically sectioned images of the birefringence of intact tissues. “The collagen structure of equine articular cartilage, characterized using polarization sensitive optical coherence tomography”, Ugryumova N, Winlove CP, Attenburrow DA and Matcher SJ, J. A standard OCT image of the optical reflectivity of intervertebral disc reveals little contrast. newton.ex.ac.uk /research/biomedical/optics/psoct.html   (520 words)

gms Optical coherence tomography Optical coherence tomography (OCT) is a non-invasive diagnostic imaging technique first introduced for ocular examination in 1991. The acquisition and interpretation of OCT findings can be difficult and is dependent on the experience of the examiner. Possibilities and limits of OCT will be addressed on the basis of relevant cases. www.egms.de /en/meetings/dog2004/04dog007.shtml   (252 words)

Clinical Trial: Optical Coherence Tomography Comparative Study Topography of diabetic macular edema with optical coherence tomography. Strom C, Sander B, Larsen N, Larsen M, Lund-Andersen H. Diabetic macular edema assessed with optical coherence tomography and stereo fundus photography. Otani T, Kishi S, Maruyama Y. Patterns of diabetic macular edema with optical coherence tomography. www.clinicaltrials.gov /ct/show/NCT00069199   (741 words)

Tomography - Wikipedia, the free encyclopedia A device used in tomography is called a tomograph, while the image produced is a tomogram. There are many different types of tomography, as listed: This is a disambiguation page: a list of articles associated with the same title. en.wikipedia.org /wiki/Tomography   (122 words)

Optical coherence tomography Optical coherence tomography (OCT) is a non-invasive technique that provides micron-scale imaging of tissue in real-time. Extraction of optical properties from OCT images of layered tissue structures OCT performs high-resolution, cross-sectional tomographic imaging of the internal microstructure in materials and biologic systems by measuring backscattered or backreflected light. www.risoe.dk /ofd/oct   (92 words)

Optical Coherence Tomography provides anterior segment imaging., Carl Zeiss Meditec Visante OCT is being showcased at the American Academy of Ophthalmology Annual Meeting in Chicago (Booth #3534), October 15-18. Visante OCT also aids postoperative evaluation by allowing imaging and measurement of intraocular lenses (IOLs) and implants in the eye. Visante OCT aids postoperative evaluation by imaging and measuring IOLs and implants. news.thomasnet.com /fullstory/472001/rss   (620 words)

Optical Coherence Tomography of Ocular Diseases, Second Edition Optical Coherence Tomography of Ocular Diseases, Second Edition is written with the clinician in mind. Optical Coherence Tomography of Ocular Diseases, Second Edition is a completely revised and updated version of this classic text. Optical Coherence Tomography of Ocular Diseases, Second Edition www.slackbooks.com /view.asp?SlackCode=66097   (700 words)

Light Source suits optical coherence tomography., NP Photonics, Inc. Passive optical components, such as power splitters, isolators, and combiners are readily available in the wavelength region of this source. The current 1-5m ASE source has a coherence length of 9 5m in air, and less than 7 5m in tissue. The Scorpion 1-5m ASE is a broadband incoherent light source based on NP's active fiber technology consisting of an energized rare-earth-doped, single-mode optical fiber. news.thomasnet.com /fullstory/459379   (763 words)

Noninvasive Blood Glucose Monitoring With Optical Coherence Tomography: A pilot study in human subjects -- Larin et al. 25 (12): 2263 -- Diabetes Care Noninvasive Blood Glucose Monitoring With Optical Coherence Tomography: A pilot study in human subjects -- Larin et al. Noninvasive Blood Glucose Monitoring With Optical Coherence Tomography is due to the coherent detection of backscattered photons, which care.diabetesjournals.org /cgi/content/abstract/25/12/2263   (349 words)

Medical optics and biotechnology : Optical coherence tomography Continuum generation in a novel photonic crystal fiber for ultrahigh resolution optical coherence tomography at 800 nm and 1300 nm In vivo detection of exercised-induced ultrastructural changes in genetically-altered murine skeletal muscle using polarization-sensitive optical coherence tomography Polarization contrast imaging of biological tissues by polarization-sensitive Fourier-domain optical coherence tomography www.opticsinfobase.org /ocisdirectory/170_4500.cfm   (487 words)

Document: Optical Coherence Tomography Humphrey's Optical Coherence Tomography Scanner provides ocular diagnostic information never before available. Specialists can more specifically diagnose, treat and manage vitreoretinal diseases and glaucoma with detailed, quantifiable images of underlying retinal structures. www.zeiss.ch /41256807004DC84E/search/D5CFE901004A064841256B76002D11F3?OpenDocument   (121 words)

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