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Topic: Oral mucosa

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	Oral Malignant Melanoma
		Oral melanomas are uncommon, and, similar to their cutaneous counterparts, they are thought to arise primarily from melanocytes in the basal layer of the squamous mucosa.
		The prevalence of oral melanoma in the Japanese population is somewhat controversial.
		As a result of the absence of corresponding histologic landmarks in the oral mucosa (ie, papillary and reticular dermis), Clark levels of cutaneous melanoma are not applicable to those of the oral cavity.
	www.oralcancerfoundation.org /facts/rare/om/index.htm (4779 words)

	Oral complications of chemotherapy and head/neck radiation: 310577 (Site not responding. Last check: 2007-10-10)
		Labial mucosa, buccal mucosa, tongue, floor of mouth, and soft palate are more severely affected by chemotherapy than attached, heavily keratinized tissues such as hard palate and gingiva; this may be due to their faster rate of epithelial cell turnover.
		Normal oral mucosa functions to (1) reduce levels of oral microorganisms colonizing the mucosa by means of shedding of the surface layer, and (2) limit penetration of many compounds into the epithelium by maintaining a chemical barrier.
		Oral complications of cancer are among the most devastating of both short and long term problems encountered by people with cancer because they effect the most basic of human activities, eating and communication.
	www.acor.org /cnet/310577.html (10149 words)

	Oral complications of cancer and cancer therapy
		The majority of oral bacterial infections are gram-negative due to the shift in the colonization of the oral cavity from predominantly gram-positive to enteric gram-negative organisms.
		Oral bleeding may be minimal, with petechiae located on the lips, soft palate, or floor of the mouth, or it may be severe, with oral hemorrhage, especially in the gingival crevices.
		Oral care protocols generally include atraumatically cleansing the oral mucosa, moisturizing the lips and oral cavity, and relieving pain and inflammation.[2] A soft toothbrush or foam swab (toothette) cleans teeth effectively and atraumatically.
	cancerweb.ncl.ac.uk /cancernet/302904.html (5051 words)

	Nutrition in Periodontal Health & Integrity of the Oral Mucosa
		The soft tissues of the oral cavity are made up of epithelial cells that have rapid rates of replication, metabolism, and maturation which require a steady supply of essential nutrients.
		Like skin, an intact oral mucosa is the first line of defense against the invasion of pathogens into the body.
		Epidemiologic and experimental studies conducted in the early 1900's identified the most common symptom of B vitamin deficiencies to be the loss of the integrity of the oral mucosa.
	www.thejcdp.com /issue006/boyd/03boyd.htm (484 words)

	Adhesive medical tapes for oral mucosa - Patent 4765983
		Adhesive medical tapes for oral mucosa comprising a support layer composed of an intestine-soluble polymer and a medicament-containing layer composed of a water-soluble polymer containing at least one kind of a steroid or non-steroid antiphlogistic and analgesic medicament.
		The object of this invention is, therefore, to provide a slow releasing adhesive medical tape for oral mucosa which is a film-form adhesive medicament and the medicament-containing layer of which is at least water-soluble and is gradually dissolved to provide the medical effect.
		In such an adhesive medical tape for oral mucosa, it is inevitable to uniformly mix, disperse, or dissolve an antiphlogistic and analgesic medicament in a watre-soluble polymer film but the aforesaid object of this invention cannot be attained by only applying or embeding the film.
	www.freepatentsonline.com /4765983.html (2688 words)

	Global Oral Health - CAPP
		Oral cancer is the commonest type in the Southeast Asian region due to both chewing and smoking tobacco habits practised.
		Oral cancer appears most commonly in the lateral boarder of the tongue and floor of the mouth.
		Oral candidosis is an opportunistic infection by the fungus Candida albicans.
	www.whocollab.od.mah.se /expl/oralmuc.html (534 words)

	Oral Pathology
		Oral Pathology: Of the infant and toddler
		Oral ulceration, pharyngitis, gingival infection unresponsive to conventional treatment, gingival oozing, hematoma, petechiae or ecchymosis formation are among the oral lesions noted.
		It reinforces the adage “you are not healthy without good oral health.” and it challenges medical and dental professionals to assume a reciprocal role in reaching the national health objectives for the Year 2010 and beyond.
	www.nypartnersinoralhealth.com /tableofcontents/oralpathology.html (2236 words)

	Oral Hairy Leukoplakia
		Oral hairy leukoplakia in a patient with acute lymphocytic leukemia.
		Oral candidiasis was observed in 9.4% of renal transplant recipients compared with 2.5% of the controls; 3.8% of renal transplant recipients exhibited erythematous candidiasis, but this was not seen in the controls.
		OBJECTIVE: Oral hairy leukoplakia (OHL) is characterised by the presence of a replicative Epstein-Barr virus (EBV) in the superficial layers of the epithelium.
	www.thedoctorsdoctor.com /diseases/oralhairyleukoplakia.htm (6894 words)

	LLU Medicine: Anatomy: Oral Histology - Questions 73-79
		In the oral cavity and continuing through the esophagus the epithelium is stratified squamous non-keratinized except where the mucosa is tightly adherent to underlying bone (the masticatory mucosa).
		In the central part of the pharynx the mucosa is tightly adherent to the underlying sheet of elastic tissue and skeletal muscle.
		The epithelium associated with respiratory mucosa is pseudostratified ciliated columnar with goblet cells.
	www.llu.edu /llu/medicine/anatomy/glossary/ans73_79.html (719 words)

	Oral Malignant Melanoma
		Background: Pigmented entities are relatively common in the oral mucosa and arise from intrinsic and extrinsic sources.
		Pathophysiology: Oral melanomas are uncommon, and, similar to their cutaneous counterparts, they are thought to arise primarily from melanocytes in the basal layer of the squamous mucosa.
		Mortality/Morbidity: Oral melanoma often is overlooked or clinically misinterpreted as a benign pigmented process until it is well advanced.
	www.oralcancerfoundation.org /facts/om (4757 words)

	NIH Guide: ORAL MUCOSA AND HIV INFECTION
		The oral mucosa differs from other mucosal surfaces in that it is generally thicker, composed of both keratinizing and non-keratinizing stratified squamous epithelial cells, and bathed in saliva.
		Yet how the oral mucosa resists HIV infection while serving as a portal for many other types of viruses such as Epstein-Barr virus or human papillomavirus is undetermined and requires further research Thus far, only a few studies suggest that oral epithelial cells may be infected with and harbor HIV.
		Emphasis must be placed on defining the potential barrier function of the oral mucosa, identifying properties of this mucosal surface that differ from those of the vagina and rectum, and determine if differences in mucosal properties are related to enhanced or diminished infection by HIV.
	grants.nih.gov /grants/guide/rfa-files/RFA-DE-04-002.html (2914 words)

	Oral cancer - Wikipedia, the free encyclopedia
		Oral cancers may originate in any of the tissues of the mouth, and may be of varied histologic types: adenocarcinoma derived from a major or minor salivary gland, lymphoma from tonsillar or other lymphoid tissue, or melanoma from the pigment producing cells of the oral mucosa.
		Oral or mouth cancer most commonly involves the tissue of the lips or the tongue.
		Smoking and other tobacco use are associated with 70 percent to 80 percent of oral cancer cases, caused by irritation of the mucous membranes of the mouth from smoke and heat of cigarettes, cigars, and pipes.
	en.wikipedia.org /wiki/Oral_cancer (1325 words)

	Oral cavity and oropharynx
		Anterior 2/3 of tongue (oral tongue): freely mobile portion of tongue that extends anteriorly from line of circumvallate papillae to undersurface of tongue at junction of floor of mouth; composed of four areas - the tip, the lateral borders, the dorsum and the undersurface (nonvillous ventral surface of tongue)
		Upper alveolar ridge: mucosa overlying alveolar process of maxilla which extends from line of attachment of mucosa in upper gingival buccal gutter to junction of hard palate; posterior margin is upper end of pterygopalatine arch
		Micro: ulcerated surface mucosa; intraductal proliferation of metaplastic squamous epithelium containing trapped mucous cells in lobular (not infiltrative) pattern; pseudoepitheliomatous hyperplasia common; vascular proliferation with prominent inflammatory infiltrate and partial necrosis of salivary glands, associated with squamous metaplasia of adjacent ducts and acini
	www.pathologyoutlines.com /oralcavity.html (2662 words)

	Oral Candidiasis
		“Oral thrush,” a fungal disease of the oral mucosa and tongue, is caused most often by
		S: Patient complains of white patches on tongue and oral mucosa, smooth red areas on dorsal tongue, burning or painful mouth areas, changes in taste sensation, sensitivity to spicy foods, and decreased appetite.
		O: PE: Patients presenting with oral candidiasis may be totally asymptomatic, so it is important to inspect the oral cavity thoroughly.
	www.seatec.emory.edu /clinicalprotocols/chpt5/OralCandidiasis.htm (863 words)

	eMedicine - Cancers of the Oral Mucosa : Article by Crispian Scully, CBE, MD, PhD, MDS (Site not responding. Last check: 2007-10-10)
		Any chronic oral lesion should be regarded with suspicion, especially when found in an older patient, when lesions appear (see History), with induration, with fixation to underlying tissues, with any recent changes in appearance, with associated lymphadenopathy, or with no obvious explanation for the lesion.
		A case-control study (ie, every oral cancer case prior to surgery and every control at the time of interview had a structured oral examination) from China found that wearing dentures, per se, is not a risk factor, although the risk was increased in men who wore dentures made from metal.
		Oral carcinoma in situ and early invasive carcinoma have an affinity for toluidine blue dye, and although several false-positive results may be encountered, these can be minimized by restaining after 14 days.
	www.emedicine.com /derm/topic565.htm (9297 words)

	Generex Biotechnology - Innovations in Drug Delivery
		Generex Oral-lyn™ is a liquid formulation of regular human insulin that is delivered to the buccal mucosa by way of the RapidMist™ device,where absorption is limited to the mouth with no entry into the lungs.
		The rich vascularity of the buccal mucosa allows for much faster absorption of insulin and a shorter total duration of activity which makes Generex Oral-lyn™ an ideal prandial insulin as it can be conveniently administered immediately prior to meals with little prospect of hypoglycemia.
		Generex Oral-lyn™ can be used as a preventative pharmacologic agent by people with pre-diabetes to delay the onset of diabetes and by patients with type-2 diabetes to delay the onset of insulin dependence and the complications associated with diabetes.
	www.generex.com /products/oral-lyn (183 words)

	ULCERATIVE LESIONS OF THE ORAL CAVITY
		Traumatic injuries to the oral mucosa are treated by removing the responsible irritant, after which healing is usually uneventful.
		Because oral candidiasis has been reported in patients using steroid sprays and solutions, prophylaxis with antifungal agents should be considered in these patients.
		Treatment of oral SCC generally involves wide local resection, radiation therapy, or both.
	www.utmb.edu /otoref/Grnds/Ulcer-oral-021016/Ulcer-oral-021016.htm (5086 words)

	RFA-DE-05-002: DEVELOPMENT OF IN VITRO MODELS OF HUMAN ORAL MUCOSA RELEVANT TO AIDS AND MUCOSAL INFECTIONS
		The oral mucosa is composed of both stratified and non-stratified epithelial cells which form a continuously renewing, protective 100 um layer in the mouth.
		The surface of the mucosa is covered by salivary carbohydrates, lipids and proteins, and interacts directly with the oral environment, containing bacteria, fungi, viruses, food, tobacco products, alcohol etc. In addition, the mucosa produces or is bathed by cytokines, chemokines, antibodies and innate host factors in saliva.
		Research on identifying protective or susceptibility factors in the oral mucosa in persons exposed to HIV would be greatly facilitated by the availability of high quality, standardized, and reproducible in vitro models of the mucosal tissue.
	grants.nih.gov /grants/guide/rfa-files/RFA-DE-05-002.html (3987 words)

	Overgrowth of oral mucosa and facial skin, a novel feature of aspartylglucosaminuria -- Arvio et al. 36 (5): 398 -- ...
		All oral specimens with the exception of one buccal overgrowth (table 1, case 6) were studied immunohistochemically for expression
		The prevalences of oral mucosal lesions in the AGU patients and the controls are presented in table 2.
		The clinical characteristics and histological diagnoses of the facial and oral lesions are summarised in table 1.
	jmg.bmj.com /cgi/content/full/36/5/398 (3597 words)

	Oral mucosa myiasis caused by Oestrus Ovis
		A case of oral mucosa myiasis in a three-year-old boy from a shepherd family living in a rural area of Iran is being reported.
		To our knowledge, this is the first reported case of oral mucosa myiasis.
		The larvae, which were placed in and around the mouth, penetrated into the gingival sulcus and positioned their heads down so the posterior spiracles could become exposed to the open air to make respiration possible.
	www.ams.ac.ir /AIM/0253/0253194.htm (1282 words)

	A WOMAN WITH SUPERFICIAL EROSIONS OF THE SKIN, ORAL MUCOSA, AND GENITALS (Site not responding. Last check: 2007-10-10)
		She was diagnosed with pemphigus vulgaris 18 months ago.
		On presentation, the patient had skin erosions over 30–35% of her body surface area, mostly concentrated over her chest, back, and thighs.
		She had oral ulcerations that were inhibiting her speech and ability to eat.
	www.med.wayne.edu /dermatology/webmichderm01/case26.htm (614 words)

	oral lesions2
		Traumatic causes of oral ulceration may be physical or chemical.
		Physical damage to the oral mucosa may be caused by sharp surfaces,
		any site of the oral mucosa including keratinized sites.
	www.uic.edu /classes/peri/peri311/lec3ls/oral_lesions2.htm (601 words)

	Oral Mucosa and Related Diseases (Site not responding. Last check: 2007-10-10)
		To acquire a body of factual knowledge about the diagnosis and management of diseases affecting the oral mucosa as a basis for future, self-directed studies.
		By the end of the course the future specialist dentist should be able to:
		Illustrate, with clinical examples, how to assess oral mucosal lesions so that appropriate management is instigated
	www.leeds.ac.uk /dental/research/postgrad/oralmuc.htm (107 words)

	eMedicine Dermatology : DISEASES OF THE ORAL MUCOSA - Online Medical Textbooks and Physician Reference Articles (Site not responding. Last check: 2007-10-10)
		You are in: Dermatology > Diseases Of The Oral Mucosa
		Dermatology - Diseases Of The Oral Mucosa Articles
		Please check with a physician if you suspect you are ill.
	www.emedicine.com /derm/DISEASES_OF_THE_ORAL_MUCOSA.htm (216 words)

	Amazon.com: Diseases of the Oral Mucosa and the Lips: Books: Konrad Bork,Nikolaus Hoede,Gunter W. Korting,Walter H. C. ... (Site not responding. Last check: 2007-10-10)
		Amazon.com: Diseases of the Oral Mucosa and the Lips: Books: Konrad Bork,Nikolaus Hoede,Gunter W. Korting,Walter H. Burgdorf,Stephen K. Young
		This clinically oriented text/atlas covers the symptoms and diseases of the oral mucosa and perioral skin.
		Translation of the second edition of the German text (1993) on oral pathology, for physicians in oral medicine, otolaryngologists, dermatologists, and general practitioners.
	www.amazon.com /Diseases-Oral-Mucosa-Lips-Konrad/dp/0721640397 (728 words)

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