| | Order and disorder in the vascular network |
 | | disorder parameters proposed in the present study were consistent with this finding, but they allowed a more detailed description of the changes in the spatial arrangement of the vascular tree induced by the treatment with angiogenic or angiostatic molecules. |
 | | disorder exhibited by the vascular network of the CAM in basal conditions and after treatment for 96 h with an angiogenic cytokine, such as fibroblast growth factor-2 (FGF-2), or with an angiostatic molecule, such as vinblastine. |
 | | In addition, three types of order exhibited by the CAM vessels were considered: (i) positional order, associated with the arrangement of the network in the membrane; (ii) topological order, associated with the homogeneity of branching occurrence along the structure; and (iii) orientational order, associated with the orientation of the branches forming the network. |
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