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Topic: Organic synthesis


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  Organic Chemistry
Organic synthesis is a pure and an applied science.
The intellectual challenge of pure organic synthesis coupled with the potential to use organic synthesis to help solve real world problems continues to attract generation after generation of talented young scholars to the field.
Students at Oregon have excellent opportunities to explore and learn both the depth and breadth of contemporary organic synthesis, and to prepare themselves for organic chemistry related careers in academia and industry.
www.uoregon.edu /~chem/organic.html   (179 words)

  
  Sloan-Kettering - Organic Synthesis
The synthesis of modified and unmodified compounds in amounts that permit their availability for in vitro and in vivo assays and for secondary assays.
It is primarily concerned with the scientific merit of each project, prioritization, and scheduling of retained projects based on the complexity of the synthesis and the timeframe of need by the user.
Because of the high level of synthetic expertise currently in the Organic Synthesis Core Facility and within the Institute, original synthetic methods may be developed to accomplish the project in a timelier, efficient, and cost-effective manner.
www.mskcc.org /mskcc/html/14209.cfm   (988 words)

  
 ››› buch.de - bücher - versandkostenfrei - Strategies and Tactics in Organic Synthesis
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis.
Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners.
We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.
www.buch.de /buch/06716/791_strategies_and_tactics_in_organic_synthesis.html   (260 words)

  
 IngentaConnect Publication: Current Organic Synthesis
asymmetric synthesis, organometallic chemistry, novel synthetic approaches to complex organic molecules, carbohydrates, polymers, protein chemistry, DNA chemistry, supramolecular chemistry, molecular recognition and new synthetic methods in organic chemistry.
The frontier reviews provide the current state of knowledge in these fields and are written by experts who are internationally known for their eminent research contributions.
Current Organic Synthesis should prove to be of great interest to synthetic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic synthesis.
www.ingentaconnect.com /content/ben/cos   (123 words)

  
 Organic Synthesis
The research carried out within the Organic Synthesis group is very largely focused on the development of novel synthetic methods and applications of these in target synthesis, most often either natural products or biologically active compounds of Pharmaceutical or Agrochemical significance.
Driven by the demands of industry and environmental considerations, much of this effort is aimed at defining new methods for the highly efficient and catalytic generation of such compounds.
The establishment of the Cardiff Centre for Physical Organic Chemistry will serve as a focal point to re-invigorate this area of research activity within the U.K., and to re-establish the U.K. as a major player in this field of research in the international arena.
www.cardiff.ac.uk /chemy/research/organicsynthesis.html   (333 words)

  
 Custom Organic Synthesis Services by Aurora Fine Chemicals
Chemical synthesis is an essential part of drug development.
Outsourcing the activity to a specialist custom synthesis house is an efficient, cost-effective means of ensuring the smooth and timely passage of new drug compounds through the pipeline.
We have over 15 years experience of satisfying the organic synthesis requirements of pharmaceutical, chemical and agrochemical companies and research institutions worldwide.
www.aurorafinechemicals.com /english/chemical-synthesis.html   (195 words)

  
 Organic Syntheses Website
Since 1921, Organic Syntheses has provided the chemistry community with annual collections of detailed, reliable, and carefully checked procedures for the synthesis of organic compounds.
Each procedure is written in considerably more detail as compared to typical experimental procedures in other journals, and each reaction and all characterization data has been carefully "checked" for reproducibility in the laboratory of a member of the Board of Editors.
Organic Syntheses procedures may be accessed either via the tables of contents of individual volumes ("journal mode") or by conducting structure and keyword searches ("database mode").
www.orgsyn.org   (360 words)

  
 CT 9/98: Building the shortest synthesis route
The skeletal bonds we cut, which must be constructed in the synthesis route, are called a bondset, and these bondsets are a basis for generating the shortest syntheses.
Imagine a synthesis route with its set of starting materials chosen so that their functional groups are correct to initiate the first construction, leave a product correctly functionalized for the second construction, and so on, continuing to construct skeletal bonds until the target skeleton is built.
In the first phase (Figure 4, left side), we see the skeletal dissection down to four starting skeletons, all found in the catalog; in fact, the intermediate skeleton B also was found, so further dissection to E and F may not be needed.
pubs.acs.org /hotartcl/chemtech/98/sep/buil.html   (2027 words)

  
 Methods in Organic Synthesis Home
Methods in Organic Synthesis (MOS) is an alerting service covering the most important current developments in organic synthesis.
It is designed with the synthetic organic chemist in mind, providing informative reaction schemes and covering new reactions and new methods.
Items are selected for inclusion in MOS only where there is detail of novel or interesting features in organic synthetic methods, so that there are no routine preparations to plough through.
www.rsc.org /Publishing/CurrentAwareness/MOS   (198 words)

  
 Microwave Assisted Organic Synthesis
This book demonstrates the underlying principles of microwave dielectric heating and, by reference to a range of organic reaction types, its effective use in synthetic organic chemistry.
Microwave assisted synthesis is now established in many industrial and academic laboratories giving access to the novel chemistry that can be carried out in a variety of organic reaction types.
Case studies, drawn from the pharmaceutical industry, illustrate the impact microwave assisted organic synthesis can have on chemical research.
www.knovel.com /knovel2/Toc.jsp?BookID=1385   (122 words)

  
 Amazon.com: Organic Synthesis: Books: Michael B. Smith   (Site not responding. Last check: )
For complete and up-to-date coverage in the area of synthesis and reactions, Organic Synthesis provides readers with a clearly written presentation that guides them through the material-carefully and methodically.
www.anton-paar.com The new Synthos 3000 from Anton Paar is a high-performance microwave instrument for organic synthesis.
Since organic synthesis is a broad and infinitely growing field, not a single book covers all the principles and gadgets of organic chemistry.
www.amazon.com /Organic-Synthesis-Michael-B-Smith/dp/0070487162   (1522 words)

  
 High-Throughput Organic Synthesis
Automated solid-phase synthesis of a small library of compounds based on such a peptidomimetic scaffold has led to the identification of potent and highly selective inhibitors of the NS3 protease enzyme.
The application of solid-phase strategies towards the synthesis of diversity libraries as well as lead optimization libraries continues to be an area of ongoing scientific experimentation.
This separation forms the basis of a new mixture synthesis technique in which members of a series of unique substrate/fluorous tag pairs are mixed, carried through a series of synthetic transformations, and then demixed using HPLC based on the fluorine content of the tag.
www.healthtech.com /2002/hto/index.htm   (3785 words)

  
 Organic Synthesis on Solid Phase
Organic synthesis on insoluble supports is a rapidly developing methodology which offers several advantages if compared to traditional synthesis in solution.
In recent years many new synthetic methods for solid-phase synthesis have been developed, and this technique is becoming a valuable alternative to traditional synthesis, in particular when large numbers of different compounds in small quantities are needed for screening.
Many tables with numerous examples illustrate the feasibility of a given reaction on insoluble supports, and all the information can be easily located either using the table of contents or the (very extensive) index.
www.angelfire.com /fl2/doerwald/spos4.htm   (186 words)

  
 The SynGen program for organic synthesis generation   (Site not responding. Last check: )
SynGen is a unique program for automatic organic synthesis generation.
It focusses on the generation of the shortest, most economic synthetic routes for a given target organic compound, and is thus a useful tool for synthesis planning.
It is based on Professor James B. Hendrickson's studies on efficiency in synthesis design and on the generalization of organic functionality and reactions.
syngen2.chem.brandeis.edu /syngen.html   (133 words)

  
 Wiley-VCH - Wyatt, Paul / Warren, Stuart - Organic Synthesis
Organic Synthesis: Strategy and Control is a sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach.
Heterocyclic chemistry is treated throughout the book with full mechanistic explanations as part of organic chemistry rather than a separate mystery.
Synthesis and Chemistry of Azoles and other Heterocycles with Two or more Heteroatoms.
www.wiley-vch.de /publish/en/books/bySubjectCH00/bySubSubjectCH51/0-471-92963-8/?sID=b3d7e0529f3bf3dcc248b8a35776767e   (286 words)

  
 Wiley::Organic Synthesis: Strategy and Control
Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds.
This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice.
Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.
www.wiley.com /WileyCDA/WileyTitle/productCd-0471929638.html   (261 words)

  
 BSP :: Current Organic Synthesis Home Page
asymmetric synthesis, organometallic chemistry, novel synthetic approaches to complex organic molecules, carbohydrates, polymers, protein chemistry, DNA chemistry, supramolecular chemistry, molecular recognition and new synthetic methods in organic chemistry.
The frontier reviews provide the current state of knowledge in these fields and are written by experts who are internationally known for their eminent research contributions.
Current Organic Synthesis should prove to be of great interest to synthetic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic synthesis.
www.bentham.org /cos   (146 words)

  
 Custom Organic Synthesis Modern Organic Synthesis Organic Laboratory Technique Organic Synthesis
Since initial research laboratory productions are not suitable for preparing thousand grams of target product, our staff will adapt and adopt a synthesis that best to meet our clients' expectations.
Under laboratory custom synthesis projects, our customer should provide literatures, methods, or their own synthesis route describing all in details.
Our chemists will evaluate synthesis feasibility prior to the initiation of the projects, and provided an estimate of cost and delivery time.
www.biosyn.com /organic.aspx   (390 words)

  
 Wiley::Aziridines and Epoxides in Organic Synthesis
Wiley / Chemistry / Organic Chemistry / General Organic Chemistry /
Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons.
The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth.
eu.wiley.com /WileyCDA/WileyTitle/productCd-3527312137.html   (241 words)

  
 Organic Synthesis and Carbon-Carbon Bond Forming Reactions
We will illustrate this approach with examples, starting with synthesis of benzene derivatives.  Starting point is usually fairly obvious – simple benzene derivatives or perhaps benzene itself.
The use of such enolate anions from carbonyl compounds is fundamental to organic synthesis and you will already have met them as intermediates in the Aldol reaction and Claisen condensation.
Very useful method for alkene synthesis as the position of the double bond is known.
www.uea.ac.uk /~c286/notes/retrosynthesis.htm   (1312 words)

  
 Organic Syntheses database in ISIS/Base format for the offline search
Organic Syntheses™, describes checked and edited experimental procedures, spanning a broad range of synthetic methodologies, and provides chemists with a compendium of new or little known experimental procedures which lead to useful compounds or that illustrate important new developments in methodology.
For every procedure, safety warnings are presented along with detailed descriptions for the preparation, purification, and identification of the compound in question.
Organic Syntheses™ is a trademark of Organic Syntheses, Inc.
www.exchemistry.com /orgsyntheses.html   (207 words)

  
 Expert: Organic Synthesis Design Expert
He has written a computer program to search any commercial database for reactions based on his published collection of definitions/descriptions of all organic reactions.
He is developing a very short total synthesis for these alkaloids.
Currently in the laboratory, he is developing a short synthesis of vitamin A. Show Secondary and Basic Areas of Expertise
www.intota.com /viewbio.asp?bioID=603270&perID=107918   (467 words)

  
 The Microwave Synthesis Information Portal - index
This conference is devoted to advances in synthesis techniques and technologies.
Environmentally benign protocols have been developed for the synthesis of various pharmaceutically active heterocycles namely 1,3,4-oxadiazoles, 1,3,4-thiadiazoles, 1,3-dioxanes, pyrazoles, hydrazones and 3,4-dihydropyrimidin-2(1H)-ones, which proceed under the influence of microwave irradiation and using eco-friendly conditions.
The meeting will be preceded by a one day course on Microwave-Assisted Organic Synthesis run by Prof.
www.microwavesynthesis.net   (363 words)

  
 Organic Synthesis - Polyhedron Laboratories, Inc.
Polyhedron Laboratories has been offering organic synthesis services since 1973.
Currently Polyhedron Laboratories is now providing combinatorial and parallel synthesis services in order to accelerate the discovery process.
This technology has been pioneered by the pharmaceutical industry, but has advanced to the point that it can be applied to all other areas of the chemical industry.
www.polyhedronlab.com /orgsyn.html   (114 words)

  
 Computer Assisted Organic Synthesis (OSET)
The OSET project is currently under development at the School of Chemistry of the National Autonomous University of Mexico by
Iván Tubert and Eduardo Tubert.The aim of the project is to develop a Computer-Assisted Organic Synthesis (CAOS) program for use in the teaching of Organic Chemistry, and retrosynthetic analysis in particular.
As far as we know, there is no other open-source project in Computer Aided Organic Synthesis.
ivan.tubert.org /caos   (206 words)

  
 Accelrys: Chemical Databases: Methods in Organic Synthesis
MOS is a selective current awareness database derived from a monthly bulletin of the same name, published by the Royal Society of Chemistry.
MOS in Accord format, showing a recent reference to a novel reaction.
View the Methods in Organic Synthesis datasheet >>>
www.accelrys.com /products/chem_databases/databases/methods_organic_synthesis.html   (153 words)

  
 Abstracts of Articles about Organic Synthesis
Abstracts of articles in the field of organic synthesis,
Ryabukhin, A. Plaskon, E. Ostapchuk, D. Volochnyuk, A. Tolmachev, Synthesis, 2007, 417-427.
Ruthenium-Catalyzed S-Propargylation of Thiols Enables the Rapid Synthesis of Propargylic Sulfides
www.organic-chemistry.org /abstracts   (254 words)

  
 Modern Organic Synthesis
Organized lecture notes designed to serve as the framework for a graduate level course in synthetic organic chemistry or as an additional resource for graduate students.
Also available with the book, which presents each student with their own preorganized set of notes, is a CD-ROM copy of the notes in PDF format which faculty can easily use for presentation in the classroom via a laptop and projector.
Number of Visitors since June 13, 1999: 19875.
www.scripps.edu /chem/boger/lecturenotes   (163 words)

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