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Topic: Organogenesis

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  Organogenesis Inc.—the world leading tissue regeneration company
Having pioneered the field, Organogenesis Inc. is the world leading regenerative medicine company.
Organogenesis specializes in bio-active wound healing, bio-aesthetics™ and bio-surgery.
Only Organogenesis has the unique skill set to take complex living therapies from research and development, through manufacturing, to successful commercialization.
www.organogenesis.com   (52 words)

  Organogenesis : About Us : Message from the CEO & President
Having pioneered the field, Organogenesis is the leading regenerative medicine company.
A new era in medicine arrived when Organogenesis received the first FDA approval for a living, human cell-based therapy.
The leading role that Organogenesis is playing in bringing this field into the mainstream is a source of pride for us, the employees of the company.
www.organogenesis.com /about_us/ceo_message.html   (383 words)

  Landes Bioscience - Home
All submissions to Organogenesis are screened for general relevance to the journal by the editor to which they are sent.
Unless they are obviously irrelevant to organogenesis, in which case they will be returned immediately with an explanation, all papers are subjected to rigorous peer review by at least two reviewers.
Organogenesis publishes cover illustrations that are taken from articles in each issue, or that are designed to accompany an accepted article.
www.landesbioscience.com /journals/organogenesis/guidelines   (2348 words)

  Once-ailing firm gets boost from Medicare - The Boston Globe
Organogenesis Inc., a once-bankrupt biotech company that manufactures artificial skin, received good news for 2004: The government Medicare program nearly doubled what it will pay for its principal product, Apligraf, to $1,199 per treatment, from $680.
Organogenesis had its reimbursement rate slashed in 2003, and sales plummeted from 500 artificial skin patches a week to 250, executives said.
Organogenesis is hoping to turn a corner on a tough year.
www.boston.com /business/globe/articles/2004/01/07/once_ailing_firm_gets_boost_from_medicare   (707 words)

 Sandoz Licenses Graftskin From Organogenesis   (Site not responding. Last check: )
Sandoz will provide Organogenesis up to a total of $37.5 million in equity investments, milestone payments, and research support, including an initial $5 million equity investment at $23.37 per share and additional equity investment of $10.5 million upon achievement of specified milestones.
Developed by Organogenesis, Graftskin(TM) is the first living skin equivalent to be submitted to the FDA for marketing approval.
Organogenesis is the first company to have successfully taken a medical product comprised of living cells from concept through clinical trials to regulatory submission for marketing approval with the FDA.
www.pslgroup.com /dg/6106.htm   (947 words)

 PRESS RELEASE Class Action Lawsuit Commenced on Behalf of Organogenesis Investors by Bernstein Liebhard & Lifshitz, LLP   (Site not responding. Last check: )
Organogenesis was not named as a defendant because it filed for bankruptcy protection in November of 2002.
Apligraf is described by Organogenesis as having a structure similar to human skin and as a "skin construct." The product's human skin-like properties allow this product to be used by doctors to aid in the healing of certain types of skin ulcers and other epidermal injuries.
Thus, Defendants lacked any reasonable basis to claim that Organogenesis was operating according to plan, that sufficient sources of funding were achieved and/or available to Organogenesis or that the Company could maintain profitability or even remain a viable entity in the foreseeable near-term.
www.marketwire.com /mw/release_html_b1?release_id=64418   (937 words)

 BioPortfolio News : Organogenesis Inc. Hires Vincent Ronfard PhD as Chief Science Officer
Organogenesis Inc. is the leading company in the world which develops living, cell based products to regenerate tissue.
Most exciting is the fact that Dr. Ronfard held the position of Senior Scientist at Organogenesis Inc. in the 1990's and returns to build on key patents which bear his name.
Organogenesis Inc. is a tissue regeneration company with the unique skill set to take complex, living therapies from RandD, through manufacturing, to successful commercialization.
www.bioportfolio.com /november_06/02_11_2006/Organogenesis_Inc_Hires.html   (408 words)

 Stimulation of benzyladenine-induced in vitro shoot organogenesis in Cucumis melo L. by proline, salicylic acid and ...   (Site not responding. Last check: )
It was hypothesized that proline may be the preferred source of reductant to generate energy as well as supply NADP for purine synthesis during in vitro shoot organogenesis in C. melo.
Reduction of shoot organogenesis in response to thioproline, a known inhibitor of proline dehydrogenase, supported this hypothesis.
Shoot organogenesis was inhibited with no callus formation at higher levels (300-1000 micro M) of salicylic acid or aspirin with and without 10 mM proline.
www.trophort.com /information/data/B02/S13/SHE92STI1931306.html   (245 words)

 Spartanburg SC | GoUpstate.com | Spartanburg Herald-Journal   (Site not responding. Last check: )
In vertebrates, a special population of embryonic cells called the neural crest has been proposed as a "fourth germ layer", and is thought to have been an important novelty in the evolution of head structures.
During organogenesis molecular and cellular interactions between germ layers, combined with the cells' developmental potential or competence to respond, prompt the further differentiation of organ-specific cell types.
Modern developmental biology is extensively probing the molecular basis for every type of organogenesis, including angiogenesis (formation of blood vessels), chondrogenesis (cartilage), myogenesis (muscle), osteogenesis (bone), and many others.
www.goupstate.com /apps/pbcs.dll/section?category=NEWS&template=wiki&text=embryo   (749 words)

 Pharmalicensing.com: Organogenesis
Organogenesis was organized as a Delaware corporation in 1985.
Organogenesis intends to efficiently develop and commercialize products by maintaining a flexible strategy for outsourcing development, manufacturing and marketing activities.
Organogenesis seek to outsource functions that are beyond capacity or where it is more cost effective to do so.
www.pharmalicensing.com /company/dc/3444   (163 words)

 Organogenesis   (Site not responding. Last check: )
For example, the cells that form the face are derived from cells that originate from the dorsal region of the head and have ventrally migrated (Gilbert 26).
The process of organogenesis begins when the notochord signals the dorsal ectoderm cells to form a dorsal tube.
Organogenesis continues with the mesoderm becoming segmented into somites.
www-personal.umich.edu /~segelj/Organogenesis.htm   (384 words)

 Novavax, Inc. Announces Research Collaboration with Organogenesis
The collaboration will combine the transdermal research technology developed in the Novavax laboratories, and the living skin technology developed by Organogenesis to explore new developments of mutual interest.
"Organogenesis' tissue engineered technology will lend itself well to our shared research interests." Novavax is a biopharmaceutical drug delivery company headquartered in Columbia, Maryland.
Organogenesis Inc. designs, develops and manufactures medical products containing living cells and/or natural connective tissue.
www.prnewswire.com /cgi-bin/stories.pl?ACCT=104&STORY=/www/story/01-07-1999/0000839954&EDATE=   (343 words)

 Analysis of inflorescence organogenesis in eastern gamagrass, Tripsacum dactyloides (Poaceae): the wild type and the ...
Analysis of inflorescence organogenesis in eastern gamagrass, Tripsacum dactyloides (Poaceae): the wild type and the gynomonoecious gsf1 mutant -- Orr et al.
At this stage of spikelet organogenesis, the upper floret was
1986 Organogenesis of the staminate and pistillate inflorescences of pop and dent corns: relationship to leaf stages.
www.amjbot.org /cgi/content/full/88/3/363   (5685 words)

 Yanfeng Lin. Molecular control of organogenesis. ISBN 951-42-6566-1
The function of type XVIII collagen in developing lung, kidney and a recombination of ureteric bud and lung mesenchyme tissue and the function of the Wnt-2b gene during kidney organogenesis were studied by using the combined methods of traditional experimental embryology and modern molecular biology.
In the developing kidney, the shorter γ2* form was localized in the mesenchyme, whereas the longer γ2 form was only present in the epithelium of the Wolffian duct and in the ureteric bud, indicating different functions for the γ2 variants.
It becomed localized to the epithelial tips in the early-stage lung, while it was confined to the epithelial stalk region and was absent from the nearly formed ureteric tips in the kidney.
herkules.oulu.fi /isbn9514265661   (654 words)

 The Endocrine Society : Organogenesis - Education & Events
The Endocrine Society : Organogenesis - Education & Events
You are here: The Endocrine Society > Subject Areas > Organogenesis > Organogenesis - Education & Events
To view all available events, visit the Worldwide Endocrine Events Calendar from the main navigation.
www.endo-society.org /subject/Organogenesis/edu_events.cfm   (64 words)

 Center for Organogenesis
The Center for Organogenesis is currently holding a competition for 1 postdoctoral fellowship award.
The goal of this NRSA Fellowship award is to provide two years of support to a postdoctoral fellow (Ph.D. and/or M.D. degree) who wishes to undertake a research project in the field of Organogenesis.
Organogenesis Mission Statement: The mission of the Center is to provide an infrastructure for the study of Organogenesis at the University of Michigan.
www.med.umich.edu /medschool/organo/fellow.htm   (202 words)

 Scientia Agricola - Optimization of in vitro organogenesis in passion fruit (Passiflora edulis f. flavicarpa)   (Site not responding. Last check: )
In vitro organogenesis of passion fruit was studied by the induction of adventitious buds from leaf discs in culture media supplemented with benzyladenine (BAP) or thidiazuron (TDZ).
After four weeks of culture on induction medium, direct organogenesis was observed with multiple shoot formations along the leaf disc cut edge.
Organogenesis did not occur in the absence of growth regulators, and both BAP and TDZ were effective in promoting adventitious buds development.
www.scielo.br /scielo.php?pid=S0103-90162005000400007&script=sci_arttext   (2420 words)

 Dr. Koop - Imitrex Oral Warnings & Precautions
Teratogenicity: Oral treatment of pregnant rats with sumatriptan during the period of organogenesis resulted in an increased incidence of blood vessel abnormalities (cervicothoracic and umbilical) at doses of approximately 250 mg/ kg/ day or higher.
Oral treatment of pregnant rabbits with sumatriptan during the period of organogenesis resulted in an increased incidence of cervicothoracic vascular and skeletal abnormalities.
Oral treatment of pregnant rats with sumatriptan during the period of organogenesis resulted in a decrease in pup survival between birth and postnatal day 4 at doses of approximately 250 mg/ kg/ day or higher.
www.drkoop.com /druglibrary/43/imitrex_oral-warnings_precautions_7.html   (1523 words)

 Organogenesis Summary
In fact, most organogenesis has begun as early as week 5 in humans (remember that a normal human pregnancy lasts an average of 40 weeks).
This is because these tiny buds of tissue hold all the primitive cells which should differentiate into the myriad number of cells necessary to create all of the varied organs of the human body.
In animal development, organogenesis is the process by which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism.
www.bookrags.com /Organogenesis   (583 words)

 Working Group on Tissuegenesis and Organogenesis for Heart, Lung, and Blood Applications
The one-day meeting, sponsored by the NHLBI Tissuegenesis/Organogenesis Interest Group (TOG), consisted of a series of discussions on five major topics as they related to advancing research toward the goal of growing tissues and organs for the repair or replacement of those lost or damaged due to injury or disease.
Tissuegenesis and organogenesis are defined here as the formation of new tissues or organs to replace damaged or absent function.
Thus progenitor cell biology is a foundation for tissuegenesis and organogenesis.
www.nhlbi.nih.gov /meetings/workshops/tissueg1.htm   (4266 words)

 Organogenesis Inc - Company Profile - CBRonline.com
Sign-up for NewsAlerts on Organogenesis Inc so that whenever news breaks on this company you are amongst the first to know.
Organogenesis is a tissue engineering company that designs, develops and manufactures medical products containing living cells and/or natural connective tissue.
Organogenesis has a novel family of bio-engineered surgical products, which include FortaPerm (engineered tissue support) and FortaGen (engineered tissue repair) that are being sold by the company's sales and marketing team.
www.cbronline.com /companyprofile.asp?guid=9F73C18E-517C-4845-B764-BC4CA49FE58C&CType=Background   (325 words)

 MedTech1.com - Organogenesis Inc.
Organogenesis Inc. is the only tissue-engineering company to have developed and gained FDA PMA marketing approval for a mass-produced product containing living human cells.
Organogenesis is leveraging its FortaFlex™ bioengineered collagen matrix technology into a family of products, and has recently achieved marketing clearance for its FortaPerm™ surgical sling and PuraPly™ wound dressing.
The Organogenesis research pipeline includes the Vitrix™ living dermal replacement, a coronary vascular graft and a liver assist device.
www.medtech1.com /companies/companies20.cfm/2F0BF09A-2C45-4052-B338-CD9A648D63DC   (185 words)

 Dr. Koop - Diflucan Warnings & Precautions
Pregnancy Category C: Fluconazole was administered orally to pregnant rabbits during organogenesis in two studies, at 5, 10 and 20 mg/ kg and at 5, 25, and 75 mg/ kg, respectively.
In several studies in which pregnant rats were treated orally with fluconazole during organogenesis, maternal weight gain was impaired and placental weights were increased at 25 mg/ kg.
There were no fetal effects at 5 or 10 mg/ kg; increases in fetal anatomical variants (supernumerary ribs, renal pelvis dilation) and delays in ossification were observed at 25 and 50 mg/ kg and higher doses.
www.drkoop.com /druglibrary/43/diflucan-warnings_precautions_5.html   (498 words)

 Brazilian Journal of Plant Physiology - Glutamine enhances competence for organogenesis in pineapple leaves cultivated ...   (Site not responding. Last check: )
In this study, the glutamine effect on the promotion of shoot-bud organogenesis from leaf base explants in pineapple cultivated on a shoot induction medium (SIM) was evaluated.
The mechanisms of amino acid influence on in vitro organogenesis are poorly understood, although it is common to use media supplemented with amino acids or hydrolyzed proteins to promote explant proliferation.
In the case of the melon (Cucumis melo), proline was the beneficial amino acid that stimulated in vitro shoot organogenesis from cotyledon explants (Milazzo et al., 1998).
www.scielo.br /scielo.php?script=sci_arttext&pid=S1677-04202005000400006&lng=en&nrm=iso&tlng=en   (3815 words)

 News: Organogenesis Inc. Hires Vincent Ronfard PhD as Chief Science Officer. Genetic Engineering News - Biotechnology ...
Organogenesis Inc. today announced the appointment of Dr. Vincent Ronfard PhD as Chief Science Officer for the Company.
Dr. Ronfard brings more than 24 years in the field of tissue regeneration and joins Organogenesis Inc. from L'Oreal (U.S.A. and Paris) where he served as Associate Vice President/Director of Reconstructed Skin Worldwide.
Organogenesis Inc. is a tissue regeneration company with the unique skill set to take complex, living therapies from R&D, through manufacturing, to successful commercialization.
www.genengnews.com /news/bnitem.aspx?name=7960374   (412 words)

 Organogenesis of the Kidney - Cambridge University Press
This description of a model system for cell differentiation and organogenesis is written by one of the foremost researchers in the area.
The main emphasis is on the mammalian kidney, but the book also deals with the development of the transien excretory organs.
As it gives the background of normal development and of control systems, it will also be of use to nephrologists working on abnormalities in the urinary tract.
www.cambridge.org /catalogue/catalogue.asp?isbn=0521035082   (136 words)

 Organogenesis is a story of (re)growth - Mass High Tech: The Journal of New England Technology:   (Site not responding. Last check: )
Organogenesis has reached a profit selling its Apligraf product with the help of a new team and model, says CFO Gary Gillheeney, kneeling at right.
Less than four years ago, Organogenesis Inc. was in bankruptcy -- on the losing end of a deal that had given Novartis AG marketing rights to its bioengineered skin product.
An IPO would also be a liquid event for investors who took the business private as part of a plan to lift the company from bankruptcy in 2003.
www.bizjournals.com /masshightech/stories/2006/12/04/story2.html?from_rss=1   (752 words)

 p53 and organogenesis   (Site not responding. Last check: )
A paper published in the December 1st issue of Genes & Development reveals a novel role for the p53 tumor suppressor pathway in organogenesis during embryonic development.
Jinrong Peng and colleagues show that the zebrafish Def protein is an organ-specific factor that represses expression of a newly identified p53 isoform to coordinate digestive organ growth.
Peng explains that "based on all data obtained in our hands thus far, we believe the increase in p53 ispform in the def mutant contributes significantly (but not fully) to cause the hypoplasia digestive organs.
www.eurekalert.org /pub_releases/2005-11/cshl-pao112305.php   (130 words)

 Organogenesis - Information from Reference.com
In animal development, organogenesis is the process by which the ectoderm,...
Organogenesis is a new peer-reviewed journal, available in print and online,...
Organogenesis continues until the definitive characteristics of the organ...
www.reference.com /search?q=Organogenesis&db=web   (167 words)

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