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| | VISCOSITY, OSMOLALITY AND PH-VALUES OF ARTIFICIAL TEARS (Site not responding. Last check: ) |
 | | In order to establish a rational basis for the selection of the most appropriate preparation, pharmacological parameters such as viscosity, osmolality, and pH-value, which are thought to be relevant with respect to efficacy and local tolerability, were determined. |
 | | Methods: Viscosity, osmolality and pH-value of 25 commercially available artifical tear solutions were determined according to the appropriate assays given in the Deutschen Arzeimittelbuch (DAB 10, V. NT V.6.25; DAB 10, V.6.3).Additionally, pH-values were determined in 4 gel-like preparations. |
 | | Conclusion: In contrast to osmolality values, which do not represent a major problem, determination of pH-values revealed that 25% of the artificial tear preparations are in the acid range. |
| www.dog.org /engl/abstract97/P447.html (231 words) |
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