Endochondralossification is one of two types of bone formation (ossification) and is the process responsible for much of the bone growth in vertebrate skeletons, especially in longbones.
During endochondralossification in the developing fetus, mesenchymal cells aggregate to form a compact grouping of cells in a process called prechondrogenic condensation.
The first site of ossification occurs in the primary center of ossification, which is in the middle of diaphysis (shaft).
The terms osteogenesis and ossification are often used synonymously to indicate the process of bone formation.
Ossification continues from this center toward the ends of the bones.
Ossification in the epiphyses is similar to that in the diaphysis except that the spongy bone is retained instead of being broken down to form a medullary cavity.
