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Topic: Oxcarbazepine

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	The Epilepsy File: Oxcarbazepine
		The efficacy of oxcarbazepine monotherapy is similar to that of phenytoin in the treatment of children and adolescents with newly diagnosed partial or generalised tonic-clonic seizures.
		Oxcarbazepine monotherapy is better tolerated than phenytoin (in both adults and children) and valproic acid (in adults), and although 75 to 90% of adult patients in 5 recent monotherapy studies reported adverse events while receiving oxcarbazepine, <8% withdrew from treatment because of them.
		Oxcarbazepine is approved as monotherapy and adjunctive therapy for partial seizures with and without secondarily generalized seizures in adults and as adjunctive therapy for partial-onset seizures in children aged 4-16 years.
	ssl.adgrafix.com /users/lifestag/epilepsy/oxcarbazepine.html (4791 words)

	Oxcarbazepine - Wikipedia, the free encyclopedia
		Oxcarbazepine is structurally a derivative of carbamazepine, adding an extra oxygen atom to the benzylcarboxamide group.
		Aside from this reduction in side effects, it is thought to have the same mechanism as carbamazepine - sodium channel inhibition - and is generally used to treat the same conditions.
		Oxcarbazepine occasionally causes fatigue, nausea, vomiting, headache, dizziness, drowsiness, and blurred or double vision.
	en.wikipedia.org /wiki/Oxcarbazepine (227 words)

	[AF] TRILEPTAL (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine, in a mean dose of 56.7 milligrams/kilogram/day (mg/kg/day), was found to be efficacious for adjunctive therapy in epilepsy in a retrospective chart review of 46 children and adolescents (mean age 10.3 years; range 1.3 to 17.9 years).
		Oxcarbazepine, 2400 milligrams/day (mg/day) in 2 divided doses, was effective as monotherapy for the treatment of refractory partial seizures in 102 patients (from 11 to 62 years of age) in a placebo-controlled, double-blind trial.
		Oxcarbazepine initiated at 600 milligrams/day, titrated to 1200 milligrams/day (both dosages in 2 daily divided doses), and maintained at the higher dose for 84 days was statistically significantly superior to placebo (p=0.046) in previously untreated patients (n=67; 8 to 69 years of age).
	listas.uninet.edu /pipermail/af/2004-October/001441.html (3343 words)

	Howstuffworks "Oxcarbazepine: A Profile of an Antiseizure Agent"
		Oxcarbazepine is used to prevent seizures in patients with epilepsy.
		Oxcarbazepine may be taken either on an empty stomach or with food or milk, unless your doctor directs you to do otherwise.
		Oxcarbazepine may cause birth defects; it is similar to carbamazepine, another medication for seizures, which is known to cause birth defects.
	health.howstuffworks.com /define-oxcarbazepine.htm (799 words)

	Oxcarbazepine
		The precise mechanism by which oxcarbazepine and MHD exert their antiseizure effect is unknown; however in vitro electrophysiological studies indicate that they produce blockade of voltage-sensitive sodium channels, resulting in the stabilization of hyperexcited neural membranes, inhibition of repetitive neuronal firing, and dimunition of propagation of synaptic impulses.
		Oxcarbazepine is rapidly reduced by cytosolic enzymes in the liver to MHD, which is responsible for the pharmacological effect of the drug.
		Oxcarbazepine decreases the plasma hormone levels (ethinylestradiol and levonorgestrel) of oral contraceptives and may therefore have the potential to cause oral contraception failure.
	www.greatvistachemicals.com /pharmaceutical_intermediates/oxcarbazepine.html (688 words)

	Oxcarbazepine for epilepsy - [Medication]
		Oxcarbazepine (Trileptal) may be used to treat partial seizures in adults and children.
		Less commonly, oxcarbazepine may lower sodium levels in the blood or cause problems with concentration, double vision, speech, coordination, and walking.
		Although the safety of oxcarbazepine during pregnancy has not been determined, its chemical makeup is very similar to carbamazepine, which has been shown to increase the risk of certain birth defects.
	www.bchealthguide.org /kbase/topic/detail/drug/tf2873/detail.htm (424 words)

	oxcarbazepine Consumer Drug Information (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine is in the FDA category C. This means that it is not known whether oxcarbazepine will be harmful to an unborn baby.
		Oxcarbazepine passes into breast milk and may be harmful to a nursing infant.
		Oxcarbazepine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants.
	www.drugs.com /MTM/oxcarbazepine.html (1484 words)

	Oxcarbazepine
		Birth Defects Highest with Oxcarbazepine: Prospective follow up of 970 pregnancies in women with epilepsy found that of their 979 offspring, 740 were exposed to maternal antiepileptic drugs (AED) during the first trimester of pregnancy.
		The occurrence of major malformations was independently associated with use of carbamazepine (adjusted OR 2.5), use of valproate (4.1), use of oxcarbazepine (10.8), low serum folate concentration (5.8), and low maternal level of education (3.0).
		Oxcarbazepine No Better at Seizure Suppression: Oxcarbazepine did as well as phenytoin and valproic acid in two different DB studies in suppressing seizures.
	www.modern-psychiatry.com /oxcarbazepine.htm (1570 words)

	MedlinePlus Drug Information: Oxcarbazepine (Systemic) (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine (oks-kar-BAZ-e-peen) is used to control some types of seizures in the treatment of epilepsy.
		However, oxcarbazepine is closely related to carbamazepine, a drug known for causing birth defects in humans.
		Valproic acid (e.g., Depakote)—Blood levels of oxcarbazepine may be decreased, causing a decrease in effectiveness and a possible increase in seizure frequency
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/500111.html (1447 words)

	Oxcarbazepine: Facts and details from Encyclopedia Topic (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine (Trileptal) is an anticonvulsant[Click link for more facts about this topic] and mood stabilizing drug mood stabilizer quick summary:
		Oxcarbazepine is structurally a derivative of carbamazepine[For more facts and a topic of this subject, click this link], EHandler: no quick summary.
		Oxcarbazepine occasionally causes fatigue, EHandler: no quick summary.
	www.absoluteastronomy.com /encyclopedia/o/ox/oxcarbazepine.htm (333 words)

	ASHP News: Novartis Warns of Dangerous Allergic Reactions to Oxcarbazepine
		Oxcarbazepine, which Novartis markets as Trileptal, is indicated for the treatment of partial seizures in patients 4 years and older with epilepsy.
		The use of oxcarbazepine should be discontinued if multiorgan failure is suspected in a patient, the labeling warns.
		Patients who have previously suffered an allergic reaction to carbamazepine are at an increased risk of hypersensitivity reactions to oxcarbazepine, according to the labeling.
	www.ashp.org /news/ShowArticle.cfm?cfid=17639309&CFToken=16479923&id=10595 (237 words)

	Oxcarbazepine. (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine is one of the recently introduced anti-epileptic drugs (AEDs) in the US.
		In addition, the initial efficacy results of oxcarbazepine in other neuropathic pain conditions and in bipolar disorders are encouraging.
		In this review, recommendations on the optimal clinical use of oxcarbazepine are given based on its pharmacokinetic profile, efficacy and tolerability in those various conditions.
	www.accelerated-learning-online.com /research/oxcarbazepine.asp (397 words)

	Epilepsy Medications: oxcarbazepine (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine is useful for treating partial seizures (simple partial, complex partial, and secondarily generalized).
		Dosage: Oxcarbazepine is supplied as 150mg, 300mg, and 600mg tablets, as well as in a 300mg/5ml suspension.
		Blood levels: The expected blood levels for the monohydroxy derivate of oxcarbazepine tend to be in the 15-30 mcg/ml range.
	www.neuro.jhmi.edu /Epilepsy/meds/trileptal.html (206 words)

	Oxcarbazepine (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine is used to treat partial seizures in adults and children.
		Dose related- These side effects might be experienced when oxcarbazepine is first initiated or when the doses are changed.
		Using oxcarbazepine with certain other medications may alter the activity of either drug, which may lead to ineffective seizure control or side effects.
	www.uic.edu /pharmacy/epilepsy/oxcarbazepine.htm (330 words)

	eDruginfo.com - oxcarbazepine (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine is approved alone or as adjunctive therapy for partial seizures in adults and children ages 4 to16.
		Prescribers are advised to consider stopping oxcarbazepine and try a different antiepileptic if the patient develops a skin reaction.
		The manufacturers suggest stopping oxcarbazepine at the first sign of such hypersensitivity and consider a different therapy.
	www.edruginfo.com /duw_oxcarbazepine2.htm (152 words)

	Oxcarbazepine (Trileptal) Bipolar, Epilepsy, Seizure Medication - hiv Oxcarbazepine
		Oxcarbazepine is a medicine to treat partial seizures in adults.
		Oxcarbazepine is widely used for neuropathic pains of all types It is taken alone or with other seizure medicines.
		Oxcarbazepine also be effective in treating conditions as varied as mood disorders like anxiety, depression and Bipolar Disorder, sleep disorders, preventing migraine headaches and reducing chronic, neuropathic pain.
	www.depression-guide.com /oxcarbazepine.htm (611 words)

	Oxcarbazepine Monotherapy Safe And Effective In Difficult-To-Treat Epilepsy (Site not responding. Last check: 2007-10-18)
		ANN ARBOR, MI -- June 27, 2000 -- New results of a study led by a University of Michigan neurologist demonstrate that a drug called oxcarbazepine is safe and effective enough to be used alone in patients with partial epilepsy who do not respond to other anti-epileptic drugs.
		Qualifying patients were then tapered off of their existing drug regimen and treated only with either the 300 mg/day or 2,400 mg/day dose of oxcarbazepine.
		Despite their failure to respond to other antiepileptic drugs, 42 percent of patients in the 2,400 mg/day group had at least a 50 percent reduction in seizures and 12 percent were seizure-free, compared with 7 percent and 0 percent respectively for the 300 mg/day group.
	www.pslgroup.com /dg/1D790A.htm (966 words)

	Oxcarbazepine Tablet (desoxyn gradumet) Information - uses, side effects for Oxcarbazepine medication
		Oxcarbazepine is related to carbamazepine, and is also used by specialists as a mood stabiliser for treating people with the psychiatric illness, bipolar affective disorder (manic depression).
		Oxcarbazepine should not be used to treat children whose symptoms may be caused by stress or a psychiatric disorder.
		Oxcarbazepine helps reduce the frequency of partial epileptic seizures, a form of epilepsy in which neural disturbances are limited to a specific region of the brain and the victim remains conscious throughout the attack.
	www.diseasesatoz.com /medications/oxcarbazepine.htm (869 words)

	Oxcarbazepine Treatment of Bipolar Disorder/JCP Abstract August 2003 (Site not responding. Last check: 2007-10-18)
		Method: A chart review of naturalistic treatment with oxcarbazepine in 42 outpatients with DSM-IV bipolar disorder (10 males, 32 females; mean ± SD age = 33.3 ± 12.4 years; 25 with bipolar disorder type I, 4 with bipolar disorder type II, and 13 with bipolar disorder not otherwise specified) was conducted.
		The mean oxcarbazepine dose was 1056.6 mg/day, and mean treatment duration was 16.2 weeks.
		Conclusion: Oxcarbazepine appeared effective in about one half of patients with bipolar disorder and was well tolerated.
	www.psychiatrist.com /abstracts/200308/080312.htm (390 words)

	Oxcarbazepine & Bipolar Disorder A Guide: Description
		Oxcarbazepine (Trileptal), a medication used to treat certain seizure disorders, is also an effective treatment for some patients with bipolar disorder (manic depression).
		Oxcarbazepine and Bipolar Disorder: A Guide is a 31 page booklet recently published by the Madison Institute of Medicine®.
		Although this booklet was written for the patient, it can also be a very informative publication for family members, medical professionals, and anyone else seeking information about the use of oxcarbazepine for bipolar disorder.
	www.miminc.org /guide_oxcarb01.html (141 words)

	Oxcarbazepine Trileptal (Site not responding. Last check: 2007-10-18)
		I am on oxcarbazepine trileptal a relatively low dose (900mg/day) of Trileptal and it seems to be the best mood stabilizer I have ever taken.
		The effect on a nursing infant is not known trileptal and alcohol and this medicine should therefore not be used by women who are breastfeeding.
		mania oxcarbazepine trileptal scales was achieved by the use of this medication.
	hachure90.t35.com /oxcarbazepine/trileptal.html (404 words)

	MedlinePlus Drug Information: Oxcarbazepine
		Oxcarbazepine is used alone or in combination with other medications to treat certain types of seizures in people who have epilepsy.
		Oxcarbazepine is in a class of medications called anticonvulsants.
		Oxcarbazepine is also sometimes used to treat bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of frenzied, abnormal excitement, and other abnormal moods).
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a601245.html (1009 words)

	Oxcarbazepine - Compare Prices and Buy Oxcarbazepine online at HQ-RX.com.
		We investigate the prices on Oxcarbazepine, conditions of sale and client-service of online pharmacies in the Internet for more than 5 years.
		After pressing the button, you are redirect on the online form, where it is necessary to confirm the choice of Oxcarbazepine and enter the personal data, address and information of your credit card.
		The prescription on Oxcarbazepine is not required at this pharmacy.
	www.hq-rx.com /drugs/Oxcarbazepine.htm (231 words)

	Oxcarbazepine Effective in Pediatric Nocturnal Frontal Lobe Epilepsy: Presented at AES (Site not responding. Last check: 2007-10-18)
		Oxcarbazepine Effective in Pediatric Nocturnal Frontal Lobe Epilepsy: Presented at AES
		After the diagnosis of NFLE was made, the children, whose ages ranged from 4 to 13, were started on antiepileptic drugs other than OXC (phenytoin, valproic acid, gabapentin, and levetiracetam) but had minimal or no response to the medication.
		They were then initiated on oxcarbazepine at 10 mg/kg/day, and the dose was increased to standard weight-based doses.
	www.pslgroup.com /dg/255c16.htm (534 words)

	Oxcarbazepine buy online without prescription
		Buy Oxcarbazepine via RxTopMeds.com offers you a simple and convenient way to save money and time while obtaining quality prescription medications at cheap prices.
		Oxcarbazepine uses: Used to treat certain types of seizures in the treatment of epilepsy.
		Yes, you can have your Oxcarbazepine order shipped to where ever you would like to receive it.
	www.rxtopmeds.com /buy/online/Oxcarbazepine.shtml (221 words)

	Trileptal Online, Description, Chemistry, Ingredients - Oxcarbazepine - RxList Monographs
		(oxcarbazepine) is an antiepileptic drug available as 150 mg, 300 mg and 600 mg film-coated tablets for oral administration.
		Oxcarbazepine is 10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide, and its structural formula is
		Oxcarbazepine is a white to faintly orange crystalline powder.
	www.rxlist.com /cgi/generic3/oxcarbazepine.htm (166 words)

	Oxcarbazepine - Drugs & Vitamins - Drug Library - DrugDigest
		Oxcarbazepine can also treat facial nerve pain from trigeminal neuralgia.
		Oxcarbazepine tablets may be taken with or without food.
		If you are female and are taking birth control pills (contraceptive pills) or using other hormonal birth control methods (like injections), you should know that the birth control may not work as well while you are taking this drug.
	www.drugdigest.org /DD/PrintablePages/Monograph/1,7765,5016,00.html (556 words)

	Oxcarbazepine - Patient UK
		Oxcarbazepine controls the convulsions (fits), suffered by epileptics, by reducing the activity of the central nervous system.
		Oxcarbazepine is available in tablet and oral solution form.
		If you suspect that you or someone else has taken an overdose of oxcarbazepine contact your doctor or go to the accident and emergency department of your local hospital at once.
	www.patient.co.uk /showdoc/30003684 (551 words)

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