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Topic: Oxytetracycline

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	Oxytetracycline - Wikipedia, the free encyclopedia
		Oxytetracycline is known as a broad-spectrum antibiotic due to its activity against such a wide range of infections.It was the second of the Tetracyclines to be discovered.
		Oxytetracycline is used to control the outbreak of American Foulbrood and European Foulbrood in honeybees.
		Oxytetracycline tablets contain magnesium, stearate, maize starch, propylene glycol, colloidal silica, sodium lauryl sulphate, E104, E110, E171, E463, E464, E553.
	en.wikipedia.org /wiki/Oxytetracycline (359 words)

	NTP: Abstract for TR-315 - Oxytetracycline Hydrochloride
		Oxytetracycline levels in bones of rats and mice (as determined fluorometrically) at the end of the 13-week studies increased with dose, the highest levels (3-10 times background levels) being observed at 50,000 ppm.
		Oxytetracycline hydrochloride was not mutagenic in Salmonella typhimurium strains TA100, TA1535, TA1537, or TA98 in the presence or absence of Aroclor 1254-induced male Sprague-Dawley rat or male Syrian hamster liver S9 when assayed according to the preincubational protocol.
		Oxytetracycline hydrochloride was mutagenic in L5178Y/TK mouse lymphoma cells in the presence but not in the absence of Aroclor 1254-induced male rat liver S9.
	ntp-server.niehs.nih.gov /ntpweb/index.cfm?objectid=0707C74D-D42D-F656-2C923295CBA23D5A (893 words)

	Oxytetracycline Residues (Site not responding. Last check: 2007-09-10)
		Oxytetracycline is an antibiotic routinely used in an extra-label manner for intrauterine therapy.
		A study was performed to establish the duration of oxytetracycline residues in milk from cows with retained fetal membranes given the antimicrobial via intrauterine infusion.
		Oxytetracycline was detected in milk of all cows during treatment, at a maximum concentration ranging from 47 to 1,800 æg/kg (ppb).
	extension.usu.edu /files/agpubs/oxytet.htm (293 words)

	Oxytetracycline (Terramycin®, Liquamycin®) - PetPlace.com
		Oxytetracycline is effective against a wide range of bacteria as well as one-celled (protozoa) organisms.
		Oxytetracycline is used in both dogs and cats to treat bacterial infections, including respiratory infections of the sinuses, wound infections, pneumonia, infections of the oral cavity and infections of the blood cells.
		Oxytetracycline is not effective against infections caused by parasites (intestinal worms), mites, viruses or fungi.
	www.petplace.com /articles/artShow.asp?artID=1558 (668 words)

	Williamson v
		The owners brought this lawsuit for veterinary malpractice, contending that the Oxytetracycline injections were not necessary and were given in a negligent manner, that the thrombosis was a result of those injections, and that the thrombosis permanently diminished Latin American's fair market value.
		Buttgenbach also testified that Oxytetracycline was sometimes indicated where there was no major problem, because the California Racing Board allowed it be given immediately prior to a race, whereas a horse given certain other antibiotics, such as penicillin, could not race for 30 days.
		Prida testified that Oxytetracycline is one of the known causes of thrombosis.
	tarlton.law.utexas.edu /dawson/cases/injure/williamson.htm (2958 words)

	oxytetracycline and polymyxin B ophthalmic, Eastern Carolina
		The ophthalmic form of oxytetracycline and polymyxin B is used to treat bacterial infections of the eyes.
		Oxytetracycline and polymyxin B ophthalmic may cause blurred vision.
		Oxytetracycline and polymyxin B ophthalmic is available with a prescription under the brand names Terak Ointment and Terramycin with Polymyxin B Ointment.
	www.uhseast.com /115344.cfm (1115 words)

	LCOR Research Publications
		Objective- To determine the effects of oxytetracycline on matrix metalloproteinase-1 (MMP-1) mRNA expression and collagen gel contraction by equine myofibroblasts in an effort to explain the mechanistic basis for the pharmacologic treatment of flexural deformities in foals.
		Oxytetracycline also induced a dose-dependent decrease in MMP-1 mRNA expression by equine myofibroblasts.
		In young foals, oxytetracycline administration may make the developing ligaments and tendons more susceptible to elongation during normal weight-bearing.
	cvm.msu.edu /lcor/ResPubs/OXY04.htm (287 words)

	Terramycin Online, Description, Chemistry, Ingredients - Oxytetracycline - RxList Monographs
		Oxytetracycline is a product of the metabolism of Streptomyces rimosus and is one of the family of tetracycline antibiotics.
		Oxytetracycline diffuses readily through the placenta into the fetal circulation, into the pleural fluid and, under some circumstances, into the cerebrospinal fluid.
		It appears to be concentrated in the hepatic system and excreted in the bile, so that it appears in the feces, as well as in the urine, in a biologically active form.
	www.rxlist.com /cgi/generic2/oxytetracycline.htm (155 words)

	Approval of Drugs for Public Fish Production (Site not responding. Last check: 2007-09-10)
		Oxytetracycline (microbiocide): The tolerance for the amount of residues of tetracyclines (including oxytetracycline) in meats and seafoods was increased from 0.1 ppm to 2.0 ppm in edible muscle tissue by CVM on December 23, 1996 (21CFR Part 556).
		Oxytetracycline (microbiocide): Data generated at the UMSC on the analytical method (HPLC) for oxytetracycline in the edible tissue of fish were reviewed by CVM and recommended as acceptable for use in a bridging study with the official microbial inhibition assay.
		There is a urgent need for all holders of INADs for oxytetracycline medicated feed and UMSC to meet soon to decide on new label claims, develop protocols for pivotal efficacy studies, identify pivotal study sites, coordinate activities, and to support pivotal efficacy studies.
	aquanic.org /publicat/interna/iafwa/3rdmidyr.htm (3673 words)

	PetPlace.com - Article: Oxytetracycline (Terramycin®, Liquamycin®)
		Oxytetracycline belongs to a general class of drugs known as tetracyclines.
		Oxytetracycline also has been used to treat protozoa infections (one-celled organisms) in animals.
		Oxytetracycline and other tetracyclines can discolor the teeth in young animals.
	www.petplace.com /articles/artPrinterFriendly.asp?conID=18159 (572 words)

	Canadian Food Inspection Agency - Compendium of Medicating Ingredient Brochures - oxytetracycline hydrochloride, ...
		As an aid in increasing oxytetracycline levels in the blood, dietary calcium may be reduced to not less than 0.6%, and not more than 0.8%.
		Pre-Starters and feeds to be fed up to and including 6 weeks of age are required to contain 0.022% of oxytetracycline hydrochloride.
		Oxytetracycline hydrochloride is compatible with the following drug/drug combinations.
	www.inspection.gc.ca /english/anima/feebet/mib/mib35e.shtml (3145 words)

	UMESC - Aquaculture Drug Research and Development - Oxytetracycline - Presentations
		Oxytetracycline Depletion from the Skin-on Fillet Tissue of Coho Salmon Cultured and Fed Oxytetracycline Medicated Feed at Water Temperatures Ranging from 4.1 to 8.5 °C. Presented at the INAD Implementation Workshop, Bozeman, Montana, August 4-6, 1999.
		Oxytetracycline Depletion from the Skin-on Fillet Tissue of Coho Salmon Cultured and Fed Oxytetracycline Medicated Feed at Water Temperatures Ranging from 4.1 to 8.5 °C. Presented at the American Fisheries Society Fish Health Section Annual Meeting and Western Fish Disease Workshop, Twin Falls, Idaho, June 9-11, 1999.
		Liquid chromatographic analysis of oxytetracycline in the edible tissue from multiple fish species: a proposed alternate method for residue depletion studies.
	www.umesc.usgs.gov /aquatic/drug_research/oxytetracycline/presentations.html (373 words)

	UMESC - Aquaculture Drug Research and Development - Oxytetracycline - Reports
		Oxytetracycline residue depletion from northern pike fillet tissue.
		Oxytetracycline depletion from skin-on fillet tissue of coho salmon cultured and fed oxytetracycline medicated feed at water temperatures ranging from 4.1 to 8.5 °C. Submitted to the U.S. Food and Drug Administration, Center for Veterinary Medicine, January 29, 1999.
		A bridging study for oxytetracycline in the edible fillet of rainbow trout: Analysis by a HPLC method and the official microbiological method.
	www.umesc.usgs.gov /aquatic/drug_research/oxytetracycline/reports.html (347 words)

	[No title] (Site not responding. Last check: 2007-09-10)
		It is used in feed as follows: Table 1 ---------------------------------------------------------------------------------------------------------------- Oxytetracycline amount Combination Indications for use Limitations Sponsor ---------------------------------------------------------------------------------------------------------------- (i) 10 to 20 grams per ton (g/....................
		mortality due to air 066104 sacculitis (air-sac- infection) caused by E. coli susceptible to oxytetracycline; prevention of coccidiosis caused by E. necatrix, E. tenella, E. acervulina, E. brunetti, E. mivati, and E. maxima..
		---------------------------------------------------------------------------------------------------------------- (3) Oxytetracycline may be used in accordance with the provisions of this section in the combinations provided as follows: [[Page 460]] (i) Carbadox as in Sec.
	dil.vetmed.vt.edu /cfr/558/450.txt (983 words)

	ARS \| Publication request: Dose Titration of Oxytetracycline Against Streptococcus Iniae Infection Blue Tilapia, ... (Site not responding. Last check: 2007-09-10)
		Oxytetracycline was found to be effective in controlling the infection in tilapia.
		Oxytetracycline dose levels tested were 25, 50, 75 and 100 mg active ingredient per kilogram of fish body weight per day.
		Survivors of the 100 mg OTC treatments were not carriers of the infection whereas 10 % of survivors receiving the 75 mg OTC level were carriers.
	ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=130572 (406 words)

	ARS \| Publication request: Dose Titration of Oxytetracycline Against Streptococcus Iniae Infection Blue Tilapia, ... (Site not responding. Last check: 2007-09-10)
		The objective of this research was to test the effectiveness of oxytetracycline (OTC) as a candidate to control streptococcosis in tilapia.
		Tilapia fingerlings were experimentally infected by Streptococcus iniae (the causative agent of the disease) and fed different levels of oxytetracycline in the diet.
		Technical Abstract: Experimental trials were performed to evaluate the efficacy of oxytetracycline (OTC) in controlling Streptococcus iniae infection in blue tilapia, Tilapia aurea.
	www.ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=130572 (406 words)

	FR Doc 03-20241
		Oxytetracycline and Neomycin Fixed-Combination Type A Medicated Articles The agency is making findings of effectiveness for oxytetracycline and neomycin fixed-combination Type A medicated articles for use in animal feed.
		the incidence of abortion and shedding of leptospirae) caused by Leptospira pomona susceptible to oxytetracycline.
		A oxytetracycline; withdrawal period has treatment and control of not been established for colibacillosis use in preruminating (bacterial enteritis) calves.
	a257.g.akamaitech.net /7/257/2422/14mar20010800/edocket.access.gpo.gov/2003/03-20241.htm (4406 words)

	699. Oxytetracycline (WHO Food Additives Series 27)
		In a study in dogs that received oxytetracycline at 0, 5 or 10 g/kg in the diet degenerative change in the germinal epithelium of the testes were noted at 10 g/kg.
		In a carcinogenicity study in mice and a similar study in rats, in which oxytetracycline was administered in the diet at doses up to 1372 and 150 mg/kg b.w./day respectively, there was no evidence of an increase in the incidence of tumours.
		In humans receiving oral treatment with oxytetracycline at 2 g, 20 mg, or 2 mg per day for 7 consecutive days, there was no evidence of resistant bacteria of the family enterobacteriaceae in the faeces at the lowest dose.
	www.inchem.org /documents/jecfa/jecmono/v27je06.htm (6027 words)

	Oxytetracycline
		The Committee, at its 45th meeting, stated that a validated analytical method for the determination of oxytetracycline residues in prawn tissue was required for evaluation at the 47th meeting of the Committee before a permanent MRL could be assigned to oxytetracycline in prawn.
		A method for the quantification of oxytetracycline in giant prawn was submitted for evaluation at the present meeting by the Department of Medical Sciences, Ministry of Public Health, Thailand.
		The oxytetracycline method is based on the Oka method for tetracyclines which is accepted as the benchmark method for this purpose (Oka et al, 1985).
	www.fao.org /docrep/W4601E/w4601e0b.htm (489 words)

	AgriLabs - The BVD Experts : Products
		Oxytetracycline Hydrochloride Soluble Powder for use in the control and treatment of the following diseases in poultry.
		Coli and fowl cholera caused by Pasturella multocida, susceptible to oxytetracycline.
		Turkeys: Control of hexamitiasis caused by Hexamita meleagridis: infectious synovitis caused by Mycoplasma synoviae and bacterial organisms associated with Bluecomb (transmissible enteritis, coronaviral enteritis), susceptible to oxytetracycline.
	www.agrilabs.com /po_anti/po_Agrimycin.html (140 words)

	Oxytetracycline - Patient UK (Site not responding. Last check: 2007-09-10)
		Oxytetracycline is used to treat various types of bacterial infections by killing or stopping the growth of the bacteria.
		It is important not to lie down for at least thirty minutes after taking oxytetracycline tablets, so that the tablet can move as swiftly as possible into the stomach.
		Oxytetracycline may cause your skin to become more sensitive to sunlight than it usually is. Try to avoid the sun and sunbeds until you know how your skin reacts or use a suncream higher than factor 15.
	www.patient.co.uk /showdoc/30003183 (935 words)

	Determination of Oxytetracycline in Bovine Kidney and Medicated Milk Replacer by Liquid Chromatography (Site not responding. Last check: 2007-09-10)
		Improvements and optimization of AOAC INTERNATIONAL Official Method 995.09 for the detection of oxytetracycline in bovine kidney at the new U.S. tolerance of 12 ppm are reported.
		Results from the kidney of a calf fed medicated milk replacer containing oxytetracycline are also reported.
		Additionally, adaptation of this method to the detection of oxytetracycline in medicated milk replacer is discussed.
	www.aoac.org /pubs/JOURNAL/1999/Nov_Dec/Isolation_of.htm (110 words)

	NetDoctor.co.uk - Information about drugs for Patients
		Oxytetracycline may reduce the effectiveness of the combined oral contraceptive pill.
		Oxytetracycline may increase the blood thinning effects of anticoagulants such as warfarin.
		If oxytetracycline is taken with acitretin, isotretinoin or tretinoin there may be an increased risk of developing raised pressure within the skull (benign intracranial hypertension).
	www.netdoctor.co.uk /medicines/showpreparation.asp?id=1978 (559 words)

	Pfizer Animal Health TERRAMYCIN® Soluble Powder Product Overview
		(oxytetracycline HCI) Soluble Powder is a broad-spectrum antibiotic in concentrated form for administration in the drinking water of cattle and other livestock.
		Contains broad-spectrum oxytetracycline for treatment of respiratory disease and bacterial scours in beef calves.
		Special Note: The concentration of drug required in medicated water must be adequate to compensate for variation in the age of the animal, feed consumption rate and the environmental temperature and humidity, each of which affects water consumption.
	www.pfizerah.com /product_overview.asp?drug=TW&country=US&lang=EN&species=BF (298 words)

	Biology - Bee Behavior
		Oxytetracycline (from Oxytetracycline Quaternary) Salt (equivalent to Oxytetracycline Hydrochloride).....
		Oxytetracycline) of this mixture further mixed with 165 g.
		WARNING: Oxytetracycline soluble powder should be fed early in the spring or fall and consumed by the bees before main honey flow begins to avoid contamination of production honey.
	maarec.cas.psu.edu /bkCD/labels/premix.html (435 words)

	ARS \| Publication request: Europium-Sensitized Luminescence Determination of Oxytetracycline in Catfish Muscle (Site not responding. Last check: 2007-09-10)
		Interpretive Summary: Oxytetracycline is the only tetracycline drug approved by the U.S. Food and Drug Administration (FDA) to treat a series of bacterial diseases found in aquaculture.
		A time-resolved luminescence method was developed in this laboratory to determine oxytetracycline residues in farm-raised catfish.
		Incurred catfish samples were used to demonstrate the performance of the method around 100 ng g-1, the European Union maximum residue level.
	www.ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=157058&pf=1 (389 words)

	Accelerated Genetics (Site not responding. Last check: 2007-09-10)
		neomycin base which is equivalent to 200 g/ton oxytetracycline hydrochloride activity and 400 g/ton neomycin base.
		of powder with 1 gallon of water to provide 100 milligrams of oxytetracycline plus 200 milligrams of neomycin base per gallon of milk replacer.
		neomycin base which is equivalent to 400 g/ton oxytetracycline hydrochloride activity and 800 g/ton neomycin base.
	www.accelgen.com /accelcalfade0.html (379 words)

	Medication Guide: Oxytetracycline
		Shares the same spectrum of activity with Tetracycline, however, other semi-synthetic tetracyclines produce longer effects and can be given in lower and and less frequent doses than can oxytetracycline.
		Oxytetracycline can retard fetal skeletal development, do not use in pregnant animals.
		Please note that it is imperative to discuss the changing, or adding of any medications during your rat’s treatment with your veterinarian, to prevent future resistance of microbes to the drugs prescribed.
	ratguide.com /meds/antimicrobial_agents/oxytetracycline.php (476 words)

	Control and Treatment of Anaplasmosis in Beef Cattle (Site not responding. Last check: 2007-09-10)
		An injection of oxytetracycline is administered every 28 days, beginning with the start of the vector season and ending 1 to 2 months after the vector season ends.
		If treatment is initiated, it is recommended that a single treatment with LA-200 (200 mg/ml oxytetracycline) at the rate of 9 mg/lb BW be administered, rather than repeated treatments with a lower concentration of oxytetracycline.
		At the first indication of anaplasmosis, gather all animals over six months-of-age and (1st) administer a single dose of oxytetracycline at rate of 3-5 mg/lb BW and (2nd) immediately offer chlortetracycline free choice in a medicated salt/mineral mix or feed block, (0.5 mg/lb BW).
	edis.ifas.ufl.edu /VM041 (1889 words)

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