| |
| | NAPE, Inc. |
 | | Dermatologists will have seen more PXE than the other doctors and would be the best to make the initial diagnosis because of their familiarity with the highly characteristic skin lesions, but they will have relatively little experience with the eye or cardiovascular (CV) aspects of the disorder. |
 | | The connection between age-related and PXE disease stems from the mechanism of scarring, specifically the proliferation of blood vessels and the associated leaking, bleeding, and scarring. |
 | | There are several common complications of PXE that result from blood vessel involvement, including intermittent claudication (pain in the calves on walking), angina (chest pain or pressure on exertion), and diminished pulses due to calcification of blood vessels. |
| www.pxenape.org /qanda.html (7541 words) |
|