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Topic: P38


In the News (Thu 10 Dec 09)

  
  Walther P 38 - Wikipedia, the free encyclopedia
The Walther P38 was a 9 mm pistol that was developed by Walther as the service pistol of the Wehrmacht at the beginning of World War II.
The French manufactured P38 pistols from captured parts at the Mauser factory from May or June of 1945 until 1946.
The P38 was the first locked-breech pistol to use a double-action trigger.
en.wikipedia.org /wiki/Walther_P38   (482 words)

  
 Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell ...   (Site not responding. Last check: 2007-10-09)
Coexpression of p38 abolished the FBP-dependent induction of c-myc (Fig.
The anti-proliferative activity of p38 was abolished by coexpression of c-myc with p38 (Fig.
In lung epithelial primary cells and carcinoma cells, p38 induced the expression of surfactants SP-B and SP-C and suppressed the expression of c-myc (Fig.
www.nature.com /ng/journal/v34/n3/full/ng1182.html   (4683 words)

  
 Norepinephrine-Induced Stimulation of p38 Mitogen-Activated Protein Kinase Is Mediated by Arachidonic Acid Metabolites ...
Levels of phospho-p38 MAPK and p38 MAPK protein in cell lysates were determined by Western blot analysis (representative blots A, C, and E) as described in the legend to Fig.
Phospho-p38 MAPK and p38 MAPK protein levels in cell lysates were determined by Western blot analysis (representative blots A, B, and D) as described in the legend to Fig.
Phospho-p38 MAPK and p38 MAPK protein levels in cell lysates were determined by Western blot analysis (representative blot C) as described in the legend to Fig.
jpet.aspetjournals.org /cgi/content/full/304/2/761   (6187 words)

  
 SB 239063, a Second-Generation p38 Mitogen-Activated Protein Kinase Inhibitor, Reduces Brain Injury and Neurological ...
Harada J and Sugimoto M (1999) An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultures cerebellar granule neurons.
Heidenreich KA and Kummer JL (1996) Inhibition of p38 mitogen-activated protein kinase by insulin in cultured fetal neurons.
Kummer TL, Rao PK and Heidenreich KA (1997) Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase.
jpet.aspetjournals.org /cgi/content/full/296/2/312   (7204 words)

  
 Nuclear protein NP60 regulates p38 MAPK activity -- Fu et al. 119 (1): 115 -- Journal of Cell Science
The precipitate was examined by immunoblotting with either p38 antibody or myc antibody as indicated.
was isolated by immunoprecipitation and incubated with p38
to a blockage of the induction of p38 phosphorylation by sorbitol
jcs.biologists.org /cgi/content/full/119/1/115   (3768 words)

  
 p38 Mitogen-activated Protein Kinase Regulation of Endothelial Cell Migration Depends on Urokinase Plasminogen ...
is regulated by the p38 MAPK pathway (30, 31), and this raises
p38 MAPK activity is required for endothelial cell migration stimulated by VEGF, S-1-P, and soluble VCAM.
Direct signaling of p38 MAPK pathway is unlikely to be responsible for VEGF-stimulated endothelial cell migration.
www.jbc.org /cgi/content/full/279/48/50446   (4919 words)

  
 Inhaled p38[alpha] Mitogen-activated Protein Kinase Antisense Oligonucleotide Attenuates Asthma in Mice American ...
A recent study showed that p38 MAPK activity in the lungs of asthmatic mice was significantly higher as compared with control mice (7).
It has also been shown that the p38 MAPK pathway is critically important for the activation of the IL-5 receptor and eotaxin receptors in eosinophils, resulting in survival, activation, degranulation, and chemotaxis of eosinophils (11-13).
A recent study revealed that the p38 MAPK inhibitor SB239063 markedly reduced ovalbumin (OVA)-induced pulmonary eosinophilia in animal models of asthma, suggesting that the p38 MAPK pathway can be a pharmacologie target for the treatment of allergic asthma (14).
www.findarticles.com /p/articles/mi_qa4085/is_200503/ai_n13486542   (897 words)

  
 MKK3 and -6-dependent activation of p38{alpha} MAP kinase is required for cytoskeletal changes in pulmonary ...
Neutrophil adherence induced an increase in the phosphorylated p38 MAPK in ECs.
Phosphorylated p38 MAPK and F-actin in a slice of ECs was examined by confocal microscopy.
The p38 mitogen-activated protein kinase mediates cytoskeletal remodeling in pulmonary microvascular endothelial cells upon intracellular adhesion molecule-1 ligation.
ajplung.physiology.org /cgi/content/full/288/2/L359   (5080 words)

  
 p38{alpha} Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac ...
Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?
Alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38: a potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response.
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression.
mcb.asm.org /cgi/content/full/24/24/10611   (5413 words)

  
 The Role of p38{alpha} Mitogen-Activated Protein Kinase Activation in Renal Fibrosis -- Stambe et al. 15 (2): 370 -- ...
kinases of the p38 pathway, is associated with an increase in
increased in obstructed kidney and unaffected by p38 MAPK blockade.
Waas WF, Lo HH, Dalby KN: The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase alpha: Implications for signal/response profiles of MAP kinase pathways.
jasn.asnjournals.org /cgi/content/full/15/2/370   (5334 words)

  
 TFPro P38 compressor   (Site not responding. Last check: 2007-10-09)
The TFPro P38 is built to last; from its heavy gauge front panel to the steel chassis; the construction is 'substantial'.
While the M/S matrix system takes care of the stability of the stereo image, and provides the ability to go from mono, right through to full stereo and beyond to an enhanced stereo (150% stereo), there are often times when there are slight gain differences and imbalances between left and right.
The P38 provides for this with a balance adjustment capable of plus and minus 6dB on each side.
www.rmcaudio.com /tfpro/p38.htm   (419 words)

  
 p38{gamma} MAPK regulation of glucose transporter expression and glucose uptake in L6 myotubes and mouse skeletal ...
is resistant to the effects by known p38 inhibitors (11).
Stimulation of MAPK cascades by insulin and osmotic shock: lack of an involvement of p38 mitogen-activated protein kinase in glucose transport in 3T3-L1 adipocytes.
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.
ajpregu.physiology.org /cgi/content/full/286/2/R342   (4773 words)

  
 Activation of p38 Mitogen-Activated Protein Kinase Is Required for Osteoblast Differentiation -- Hu et al. 144 (5): ...
Inhibition of p38 MAPK reduced the expression of ALP in primary calvarial osteoblasts.
Inhibition of p38 MAPK affected the expression of osteocalcin (A) and mineral deposition (B) in calvarial osteoblasts.
p38 MAPK and ERK1/2 were activated during the differentiation of osteoblasts.
endo.endojournals.org /cgi/content/full/144/5/2068   (4339 words)

  
 p38 and ERK1/2 Coordinate Cellular Migration and Proliferation in Epithelial Wound Healing: EVIDENCE OF CROSS-TALK ...
Immunostaining of p38 and ERK1/2 at the wound edge and at the limbal region of corneal epithelia in organ-cultured rabbit corneas.
p38 and ERK1/2 were immunostained in the epithelial cells and underlying stromal cells of all groups.
the MAPKs, p38, was activated and translocated to nucleus.
www.jbc.org /cgi/content/full/278/24/21989   (5785 words)

  
 p38 Mitogen-Activated Protein Kinase Mediates a Negative Inotropic Effect in Cardiac Myocytes -- Liao et al. 90 (2): ...
p38 MAPK was unable to increase troponin I phosphorylation.
B, Activation of p38 MAPK significantly reduces the maximal shortening velocity (VS) and relaxation velocity (VR); this effect is also largely prevented by coexpression of the p38 dominant-negative mutant.
Lanes 3 and 4, p38 MAPK-induced phosphorylation of recombinant ATF-2, a native substrate for p38.
circres.ahajournals.org /cgi/content/full/90/2/190   (5067 words)

  
 The role of differential activation of p38-mitogen-activated protein kinase in preconditioned ventricular myocytes -- ...
Panel C represents the mean activation of p38, p42 and p44 during simulated ischemia/reoxygenation expressed as a ratio of that seen in naive cells in 5 independent experiments.
B) p38 activation was detected using phospho specific p38 antibodies (i) and total p38 was detected using anti-p38 antibodies (ii).
Activation of p38 isotypes during ischemia in untreated and preconditioned cells.
www.fasebj.org /cgi/content/full/14/14/2237   (5767 words)

  
 Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid ...
Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells -- Uddin et al.
After 20 h, cells were harvested and the percentage of apoptotic cells in each sample was determined by flow cytometry using annexin V and propidium iodide as apoptotic markers.
The p38 MAPK subfamily is generally activated in response to
www.pnas.org /cgi/content/full/101/1/147   (3415 words)

  
 Diverse Mechanisms of Myocardial p38 Mitogen-Activated Protein Kinase Activation: Evidence for MKK-Independent ...   (Site not responding. Last check: 2007-10-09)
The total p38 signal is strong because of virally mediated overexpression.
Gysembergh A, Simkhovich BZ, Kloner RA, Przyklenk K. p38 MAPK activity is not increased early during sustained coronary artery occlusion in preconditioned versus control rabbit heart.
Role of G proteins and modulation of p38 MAPK activation in the protection by nitric oxide against ischemia-reoxygenation injury.
circres.ahajournals.org /cgi/content/full/93/3/254   (4634 words)

  
 P-38 Can Opener - The Armys Greatest Invention.
The 6 or 7 p38 can openers I had in my carry-on were not even noticed.
I was the screener and told him to empty his pockets, of which was his P38 which set off the detector.
From then on she used my p38 every time she needed it which caused some friction because she always misplaced my keys, I finally went to a surplus store and got her one which she still uses occasionally to this day but has switched to the newer electric can openers in our older years!
www.georgia-outfitters.com /page52.shtml   (8916 words)

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