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Topic: Pacinian Corpuscle

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Mechanoreceptor

Afferent

Parietal lobe

	X. The Organs of the Senses and the Common Integument. 1e. Peripheral Terminations of Nerves of General Sensations. ...
		The tactile corpuscles of Grandry occur in the papillæ of the beak and tongue of birds.
		The tactile corpuscles of Wagner and Meissner (Fig.
		These tactile corpuscles occur in the papillæ of the corium of the hand and foot, the front of the forearm, the skin of the lips, the mucous membrane of the tip of the tongue, the palpebral conjunctiva, and the skin of the mammary papilla.
	www.bartleby.com /107/233.html (1304 words)

	2. Tutorial (Site not responding. Last check: 2007-10-12)
		Pacinian corpuscles are highly sensitive pressure receptors (approximately 2mm x 0.5mm) located deep in the dermis, as well as other areas such as joint capsules and mesenteries.
		Pacinian corpuscles are therefore completely (or rapidly) adapting, and respond best to vibration rather than to prolonged pressure.
		Meissner's corpuscles are touch and superficial pressure receptors which are located on the epidermis-dermis boundary, especially on the fingertips, palm, sole of the foot and nipple.
	d-mis-web.ana.bris.ac.uk /calnet/Recep/page2.htm (1389 words)

	Virtual Hospital: Atlas of Microscopic Anatomy: Section 1 - Cells (Site not responding. Last check: 2007-10-12)
		Pacinian corpuscles are mechanoreceptors found in the pancreas of cats but not man. In man and other animals, they are readily seen in sections of the dermis from the fingers and palm of the hand, the conjunctiva, near joints, in the mesenteries, branching blood vessels, penis, urethra, clitoris, parietal peritoneum, and loose connective tissue.
		The Pacinian corpuscle is a pressure receptor and responds to high-frequency vibratory stimuli.
		Pacinian corpuscles vary in size, but many are large enough to be easily dissected without magnifying lenses in the fingers of man.
	www.vh.org /adult/provider/anatomy/MicroscopicAnatomy/Section06/Plate06124.html (198 words)

	Pacinian Corpuscle [ (Site not responding. Last check: 2007-10-12)
		The cross section of a large Pacinian corpuscle in the center of the field.
		This corpuscle is shown deep in the dermis of the skin.
		The corpuscle is surrounded by the loose fibrous connective tissue of the dermis, and there are several small blood vessels visible in the dermis.
	www.dmacc.cc.ia.us /instructors/pacinian.htm (60 words)

	Chapter 4 - Receptor Properties: Receptor Potentials and Coding
		The corpuscles are found in connective tissue of the mesentery and the popliteal fossa among other places; their function is largely unknown but they seem suited to sense and signal vibration.
		When the stimulator presses down on the corpuscle, as shown in the lower trace by an upward deflection of the stimulus monitor trace, an hypopolarizing generator potential is initiated in the receptor (upper trace).
		In the Pacinian corpuscle, which shows an extreme of rapid adaptation, the adaptation is slowed considerably by removal of the lamellae and application of the stimulus directly to the nerve fiber.
	www.unmc.edu /Physiology/Mann/mann4.html (5208 words)

	Nikon MicroscopyU: Confocal Image Gallery - Pacinian Corpuscle
		When the politician is advised to go "squeeze some flesh" or shake hands with the potential constituents, it is the Pacinian corpuscles, somatosensory receptors of the hands and feet, that are able to detect character as expressed by a firm, confident handshake, an indecisive loose grip, or an over-zealous bone-crusher.
		A feature of both human and non-human primates, the Pacinian corpuscle is a mechanoreceptor that responds to pressure or any kind of mechanical stimulus that causes deformation of the corpuscle surrounding the single afferent nerve fiber.
		In its resting state, the Pacinian corpuscle in cross-section resembles a dartboard with the nerve ending at the bull's eye.
	www.microscopyu.com /galleries/confocal/paciniancorpuscle.html (423 words)

	Basic Sensory Receptor Physiology
		The Pacinian Corpuscle is one of a variety of receptors located in your skin, and is and ideal model receptor to use for discussion of how receptors transduce stimuli.
		Pacinian Corpuscles are examples of what we call mechanoreceptors because what they respond to is pressure applied to the skin's surface.
		Thus, it is the frequency of action potentials being sent to the brain by the Pacinian Corpuscle that 'informs' the brain about the strength of the stimulus (i.e., the amount of pressure being applied to the corpuscle).
	www.unm.edu /~toolson/Receptor_Function_Handout.html (1161 words)

	[No title] (Site not responding. Last check: 2007-10-12)
		Pacinian corpuscles are composed of connective tissue and afferent neurons.
		Pacinian corpuscles in the viscera tend to cause the sensation of pressure when stimulated, while Pacinian corpuscles in tendons, ligaments and joints may detect stretch.
		Pacinian corpuscles in the integument produce the sensation of vibration and pressure.
	www2.norwich.edu /pinkhamc/BI_215/Lab/manual/Lb15_3_Phys_of_SomatSens_S.doc (1601 words)

	[No title] (Site not responding. Last check: 2007-10-12)
		The corpuscle is nestled in a sensory dermal papilla.
		These corpuscles usually lie deep in the dermis, especially of the hand and foot.
		Pacinian corpuscles are also found at various other sites in the body like the tendons, perimysium, mesentery and external genitalia.
	www.georgetown.edu /dml/educ/micro/integ/integ.txt (1614 words)

	Mechanoreceptors
		Mechanical pressure of varying strength and frequency is applied to the corpuscle by the stylus.
		Deforming the corpuscle creates a generator potential in the sensory neuron arising within it.
		When pressure is first applied to the corpuscle, it initiates a volley of impulses in its sensory neuron.
	users.rcn.com /jkimball.ma.ultranet/BiologyPages/M/Mechanoreceptors.html (788 words)

	1aBV1 Biophysical properties of a tactile mechanoreceptor: The Pacinian (Site not responding. Last check: 2007-10-12)
		The Pacinian corpuscle is a tactile mechanoreceptor composed of a neural element surrounded by a multilayered, fluid-filled accessory capsule.
		Receptor potentials recorded from isolated Pacinian corpuscles in response to sinusoidal vibrations have nonlinear, asymmetric full-wave rectified transfer functions.
		The Pacinian corpuscle's accessory capsule was studied experimentally and modeled theoretically to determine its mechanical contribution to the observed physiological response.
	www.auditory.org /asamtgs/asa95wsh/1aBV/1aBV1.html (221 words)

	Nikon MicroscopyU: Confocal Image Gallery - Mammalian Vater-Pacini (Pacinian) Corpuscles
		Together, with the non-encapsulated receptors and the Meissner corpuscle (tactile and touch receptor), Ruffini corpuscle (heat receptor), and Krause corpuscle (cold receptor), they compose the mechanoreceptor system that provides stimuli to the somatosensory cortex of the brain.
		These corpuscles are responsible for detecting pressure or coarse touch, vibration and tension.
		Pacinian corpuscles are located in the deep layers of the dermis of both hairy and glabrous (smooth) skin (e.g., fingers and toes) and in the mesentary tissue of some organs.
	www.microscopyu.com /galleries/confocal/mammalvaterpacinicorpuscle.html (372 words)

	MSM Histology: Sense Organs (Site not responding. Last check: 2007-10-12)
		Much of this topis is covered in Neuroanatomy in the spring, especially the eye and ear.
		Slides 18-21 are of Pacinian and Meissner's corpuscles.
		This particular viewis from a whole mount of mesentery, so you are seeing the corpuscle three-dimensionally.
	www.msm.edu /human_morph/histo/organs/senses.htm (254 words)

	Biology Web (Site not responding. Last check: 2007-10-12)
		Being one of the simplest forms of sensor in the body, the pacinian corpuscle is a mechanoreciptor that is used to detect pressure applied to the skin, especially sensitive to rapid movement and vibration.
		Relative to other sensory cells, the pacinian corpuscle is huge.
		The pacinian corpuscles are also very good at adapting to their environment.
	www.bionet.0catch.com /neurones.html (293 words)

	Pacinian corpuscle
		Pacinian corpuscles are present in the skin, some mucous membranes etc. They are mechanoceptors, responding to pressure, or any kind of mechanical stimulus causing a deformation of the corpuscle.
		The Pacinian corpuscle has a single afferent nerve fiber.
		If the pressure is now released, the corpuscle as a whole will resume its original shape, but the nerve ending will be deformed in the process:
	www.neuro.uu.se /fysiologi/gu/nbb/lectures/Pacini.html (208 words)

	Phase coherence in vibration-induced responses of tactile fibres associated with Pacinian corpuscle receptors in the ...
		Phase coherence in vibration-induced responses of tactile fibres associated with Pacinian corpuscle receptors in the cat -- Greenstein et al.
		Phase coherence in vibration-induced responses of tactile fibres associated with Pacinian corpuscle receptors in the cat
		with Pacinian corpuscle (P.c.) receptors in the forelimb footpads.
	jp.physoc.org /cgi/content/abstract/386/1/263 (552 words)

	Lamellated (Pacinian) Corpuscle (Site not responding. Last check: 2007-10-12)
		Lamellated corpuscles are also distributed through the hypodermis and joints.
		The nerve fiber in the center of the corpuscle is surrounded by gel-filled layers - kind of like a soft onion.
		When pressure is applied to one point, it pushes in on the outer layer, which pushes in on the next layer, and so on, until the nerve fiber is bent.
	science.tjc.edu /Course/BIOLOGY/bott/anp1_online/skin/Pac_corp.htm (98 words)

	Sensory Receptors (Site not responding. Last check: 2007-10-12)
		Each Pacinian corpuscle contains the dendritic terminal of a single sensory neuron (with its cell body located in the DRG).
		In the case of the Pacinian corpuscle, a very forceful pressing on the skin activates it.
		Going back to the Pacinian corpuscle, a mechanical deformation of the sensory dendrite causes a depolarization to occur within the dendrite.
	distance.stcc.edu /AandP/AP/AP2pages/Units14to17/unit15/sensory.htm (979 words)

	Caption (Site not responding. Last check: 2007-10-12)
		This low magnification view shows a whole mount of a Pacinian corpuscle, a pressure receptor.
		Pacinian corpuscles are large, ovoid structures composed of layers of cells organized like the layers of an onion.
		In the center of the corpuscle is an unmyelinated nerve fiber ending.
	casweb.cas.ou.edu /pbell/Histology/Captions/Nerve/41.pacinian.wm.10x.html (53 words)

	Lectin and Proteoglycan Histochemistry of Feline Pacinian Corpuscles -- Sames et al. 49 (1): 19 -- Journal of ...
		Lectin and Proteoglycan Histochemistry of Feline Pacinian Corpuscles
		of the corpuscle, with the exception of the axon.
		Pawson L, Slepecky NB, Bolanowski SJ (2000) Immunocytochemical identification of proteins within the Pacinian corpuscle.
	www.jhc.org /cgi/content/full/49/1/19 (3735 words)

	Caption (Site not responding. Last check: 2007-10-12)
		This low magnification view of a whole mount of the mesentery shows a pressure receptor, the Pacinian corpuscle, a large, ovoid structure.
		Pacinian corpuscles are composed of a myelinated nerve endings surrounded by a capsule.
		Go to a section of a Pacinian corpuscle
	casweb.cas.ou.edu /pbell/Histology/Captions/Integument/41.pacinian.wm.10x.html (43 words)

	Zoology 214 Lecture 20: October 3, 2001 (Site not responding. Last check: 2007-10-12)
		Pacinian corpuscle is a rapidly adapting touch receptor
		Pacinian corpuscle responds with brief on and off responses (frequently one spike)
		The Pacinian corpuscle anatomically is a naked nerve ending surrounded by concentric layers of cellular membranes and fluid filled spaces (onion-like appearance)
	www.humboldt.edu /~bao3/214lectures/214Lecture20.htm (399 words)

	[No title]
		The Pacinian Corpuscle is a special nerve ending that transforms mechanical vibration, or pressure, into nerve impulses.
		What all of this gobbledygook is trying to say is that the Pacinian Corpuscle responds best to a square wave signal.
		Where the time-rate-of-change of the signal is more important than the amplitude of the pressure applied to the corpuscle.
	www.textfiles.com /bbs/KEELYNET/BIOLOGY/mind9.asc (2142 words)

	Projections from Pacinian corpuscles and rapidly adapting mechanoreceptors of glabrous skin to the cat's spinal cord -- ...
		Projections from Pacinian corpuscles and rapidly adapting mechanoreceptors of glabrous skin to the cat's spinal cord -- Brown et al.
		Projections from Pacinian corpuscles and rapidly adapting mechanoreceptors of glabrous skin to the cat's spinal cord
		All Pacinian corpuscle axons that could be traced into the
	jp.physoc.org /cgi/content/abstract/307/1/385 (348 words)

	Thick Skin II
		Also be aware that there are elastic fibers present in the Reticular layer but are not showing up because of the use of H and E stain.
		They are very easy to miss when examining with the scope becuaAgain these will always be located with in the dermal papillae that project in to the epidermis.
		This is an image of a Pacinian Corpuscle, (outlined by the blue dotted lines).
	www3.umdnj.edu /histsweb/lab11/lab11thickskin2.html (391 words)

	Chapter 14 notes (Site not responding. Last check: 2007-10-12)
		The nerve terminal of a Pacinian corpuscle is surrounded by a spherical capsule with multiple layers (like an onion)
		The are also found in tendons, where they serve as proprioceptors.
		In addition to Pacinian corpuscles, there are golgi tendon organ, muscle spindle organs, and Ruffini's end organs.
	soma.npa.uiuc.edu /courses/bio303/Chapter14_answers.htm (579 words)

	Laboratory 14: Integumentary System and Breast
		Understand the function of Meissner's and Pacinian corpuscles.
		Examine and identify the cell types and connective tissue fibers studied previously in Laboratories 8 and 11.
		Identify Meissner's corpuscles present in some, but not all, of the dermal papillae.
	medinfo.ufl.edu /year1/histo/review/lab14.html (1385 words)

	FACILITATION BY PREVIOUS ACTIVITY IN A PACINIAN CORPUSCLE -- Loewenstein 41 (4): 847 -- The Journal of General ... (Site not responding. Last check: 2007-10-12)
		FACILITATION BY PREVIOUS ACTIVITY IN A PACINIAN CORPUSCLE -- Loewenstein 41 (4): 847 -- The Journal of General Physiology
		spontaneously by the corpuscle, and which fall on the supernormal
		that of the generator potential during the corpuscle's relative
	www.jgp.org /cgi/content/abstract/41/4/847 (157 words)

	Simulation of motion on the skin. IV. Responses of Pacinian corpuscle afferents innervating the primate hand to stripe ...
		Responses of Pacinian corpuscle afferents innervating the primate hand to stripe patterns on the OPTACON -- Palmer and Gardner 64 (1): 236 -- Journal of Neurophysiology
		Responses of Pacinian corpuscle afferents innervating the primate hand to stripe patterns on the OPTACON
		To measure spatial acuity of Pacinian corpuscle (PC) afferents in the
	jn.physiology.org /cgi/content/abstract/64/1/236 (397 words)

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