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Topic: Pancreatic juice


  
  p010221a - Pancreatic Cancer - Early Detection
Title: Diagnosis of pancreatic cancer by cytology and measurement of oncogene and tumor markers in pure pancreatic juice aspirated by endoscopy.
Abstract: BACKGROUND/AIMS: Cytological examination of pancreatic juice is useful in the diagnosis of an occult cancer of the pancreas.
CONCLUSIONS: Cytological examination of pancreatic juice is useful in the diagnosis of an early and potentially curable in situ cancer of the pancreas.
www.emory.edu /WHSCL/grady/amreport/litsrch00/p010221a.html   (1010 words)

  
 [No title]
Because pancreatic malignancy is usually diagnosed at an advanced stage, when the tumor is no longer resectable, the development of new early diagnostic assays could have a major effect on the outcome of this disease.
Detection of these mutations in specimens obtained by needle aspiration [5], from pure pancreatic juice [6, 7], or from stools [8] could be a clinically useful diagnostic marker for early pancreatic malignancies.
Our purpose was to detect mutations of the K-ras 12th codon in cells from pure pancreatic juice collected during endoscopic retrograde cholangiopancreatography, so that we could evaluate the diagnostic value of this test in differentiating benign from malignant pancreatic disease in a large group of patients.
www.lycos.com /info/pancreatic-cancer.html   (608 words)

  
 Pancreatic Cancer
This pancreatic juice is passed along the main pancreatic duct to enter the small intestine at the head of the pancreas.
Most pancreatic tumours start in the cells of the pancreatic duct system and are more frequently situated in the head of the pancreas than in the body or tail.
The only recognised treatment for pancreatic cancer is surgery but because of the depth of the pancreas in the upper abdomen and the difficulty in diagnosing it at an early stage, surgical results are very disappointing, as the tumour is usually inoperable by the time the diagnosis is made.
www.dew-health.org /html/pancreatic_cancer.html   (443 words)

  
 ACS :: What Is Cancer of the Pancreas?
The exocrine gland produces pancreatic “juice,” which contains enzymes that help you digest fats, proteins, and carbohydrates in the food you eat.
Treatment of an exocrine pancreatic cancer is mostly based on the stage of the cancer, not its exact type.
Ampullary cancers are included together with pancreatic cancer in this document because their treatments are very similar.
www.cancer.org /docroot/CRI/content/CRI_2_4_1X_What_is_pancreatic_cancer_34.asp?rnav=cri   (746 words)

  
 Pancreatic cancer
Pancreatic cancer is an abnormal, uncontrolled growth of cells in the pancreas, which is a digestive gland located behind the stomach.
Adenocarcinoma, often beginning the in the pancreatic ducts, is the most prevalent type of pancreatic cancer.
In cases of advanced disease, radiation therapy and/or chemotherapy may be used, or palliative surgery may be performed to, for example, bypass areas obstructed by tumor growth (such as blockages in the bile duct or small intestine).
www.antigenics.com /diseases/pancreaticcancer.html   (1035 words)

  
 World J Gastroenterol
Pancreatic juice was collected on ice from the fistula during PN or EN and on d 1, 4, 7 before and after using octreotide, respectively.
The output of the pancreatic juice decreased by 50%, that of amylase by 71% and that of glucose slightly increased.
The output of pancreatic juice decreased from 725 mL/24 h to 151 mL/24 h, the rate of spontaneous fistula closure was 78%.
www.wjgnet.com /1007-9327/10/2419.asp   (3311 words)

  
 PanCAN - Working Together for a Cure™
Pancreatic insufficiency, decreased output of pancreatic enzymes, is associated with abdominal pain, bloating, gas, indigestion and the passing of undigested food in the stool.
Some of these conditions are: pancreatic insufficiency, status post surgery of the pancreas (ie, Whipple procedure), removal of the pancreas (ie, total pancreatectomy), pancreatic obstruction due to stone formation in the pancreatic/biliary duct, pancreatic/duodenal tumors or ductal narrowing and cystic fibrosis.
Pancreatic insufficiency is common in pancreatic cancer patients and may cause vague abdominal discomfort, pain, abdominal distention, excessive flatus (gas), belching, diarrhea, steatorrhea (fat indigestion) and weight loss.
www.pancan.org /Patient/Pancreatic/Diet/pancreatic.html   (1149 words)

  
 Genentech: Products - Disease Education - Pancreatic Cancer Fact Sheet
Pancreatic cancer is the uncontrolled growth of malignant (cancerous) cells formed in the tissues of the pancreas.
Although pancreatic cancer accounts for just two percent of new cancer cases in the United States, it is the fourth leading cause of all cancer deaths.
Pancreatic cancer is difficult to treat as it is often resistant to chemotherapy and radiotherapy, and tends to spread quickly to other parts of the body,
www.gene.com /gene/products/education/oncology/pancreaticcancerfact.jsp   (622 words)

  
 Pancreatic Cancer: The Facts - Rhode Island Cancer Council, Inc.
Digestive pancreatic juice is released by way of ducts that connect to the common bile duct, which carries bile from the liver.
Pancreatic Cancer is the 11th most commonly diagnosed cancer in the U.S. About 29,000 people are expected to be newly diagnosed with Pancreatic Cancer each year.
Pancreatic Cancer is very difficult to diagnose because it normally does not cause obvious symptoms until the cancer is well developed.
www.ricancercouncil.org /cancer-info/pancreatic-cancer-facts.php   (1078 words)

  
 Pancreatic juice - Wikipedia, the free encyclopedia
Pancreatic juice is a juice produced by the pancreas.
Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions.
Pancreatic juice secretion is regulated by the hormone secretin, which is released by the duodenum upon detection of proteins and fats.
en.wikipedia.org /wiki/Pancreatic_juice   (135 words)

  
 Pancreas - Wikipedia, the free encyclopedia
The pancreatic duct runs the length of the pancreas and empties into the second part of the duodenum at the ampulla of Vater.
The pancreas is supplied arterially by the pancreaticoduodenal arteries, themselves branches of the superior mesenteric artery or of the hepatic artery (branch of celiac trunk from the abdominal aorta).
Pancreatic secretions from ductal cells contain bicarbonate ions and are alkaline in order to neutralize the acidic chyme that the stomach churns out.
en.wikipedia.org /wiki/Pancreas   (835 words)

  
 Gastroenterology Chapter 12 Pancreatic Functions
Earlier recognition of pancreatic dysfunction may improve the management of the patient's disease and his or her quality of life.
This technique allows the measurement of pure pancreatic juice uncontaminated by biliary or intestinal secretions, but this method is possibly no more sensitive than other tests in the diagnosis of pancreatic disease.
It is elevated during an attack of pancreatitis and in renal failure, and is decreased in severe pancreatic insufficiency, cystic fibrosis and insulin-dependent diabetes without exocrine insufficiency.
www.gastroresource.com /GITextbook/en/chapter12/12-3-pr.htm   (1686 words)

  
 Canine pancreatic juice stimulates the release of secretin and pancreatic secretion in the dog -- Song et al. 277 (3): ...
Pancreatic secretions of fluid and bicarbonate in phase I were 0.15 ± 0.05 ml/15 min and 2.53 ± 0.51 µeq/15 min, respectively.
In vitro incubation of Lipomul with pancreatic juice.
Presence of a secretin releasing factor in canine pancreatic juice and its characterization (Abstract).
ajpgi.physiology.org /cgi/content/full/277/3/G731   (2648 words)

  
 Pancreatic Cancer UK :: pancreatic cancer - pancreatic enzyme replacement therapy
Pancreatic insufficiency, that is decreased output of the pancreatic enzymes lipase (responsible for digestion of fat), protease (responsible for digestion of proteins) and amylase (responsible for digestion of carbohydate), is common in pancreatic cancer patients, especially after surgery.
It is obvious that pancreatic insufficiency is likely to be a problem with patients who have undergone surgery to have part of the pancreas removed.
Pancreatic enzyme supplements are also called pancreatin which is a combination of pancreatic enzymes that are normally produced naturally by the body.
www.pancreaticcancer.org.uk /PCpancreaticenzymes.htm   (1129 words)

  
 High proportion of mutant K-ras gene in pancreatic juice of patients with pancreatic cystic lesions -- Tateishi et al. ...
Pure pancreatic juice was collected from the pancreatic duct during ERCP with the injection of secretin.
Detection of K-ras gene mutations at codon 12 in the pancreatic juice of patients with intraductal papillary mucinous tumors of the pancreas.
Quantitative analysis of ras gene mutation in pancreatic juice for diagnosis of pancreatic adenocarcinoma.
gut.bmjjournals.com /cgi/content/full/45/5/737   (2755 words)

  
 Information about Pancreatic Cancer   (Site not responding. Last check: 2007-10-17)
Pancreatic cancer is the fourth leading cause of cancer death in men and women.
Pancreatic Cancer is the #4 cancer killer in the United States amongst both men and women.
Pancreatic Cancer does not discriminate by age, gender or race and 99% of those diagnosed with the disease will die within 1 year of diagnosis.
macfoundation.tripod.com /id6.htm   (740 words)

  
 eMedicine - Pseudocyst, Pancreatic : Article Excerpt by: Michael AJ Sawyer, MD
This is a critical point in the differentiation of pancreatic pseudocysts from cystic neoplasms of the pancreas.
In this process, the common etiologic insult that causes leakage of pancreatic juice and pseudocyst formation is pancreatic ductal disruption.
In acute pancreatitis, the ductal disruption is secondary to necrosis of part of the pancreas and subsequent duct leakage.
www.emedicine.com /radio/byname/pseudocyst-pancreatic.htm   (630 words)

  
 Pancreatic Enzymes at Total Health Discount Vitamins
The existence of this circulation of pancreatic enzymes is quite similar to the recycling of bile salts by the liver.
Of further interest is the possibility that oral supplementation with pancreatic enzymes may have a sparing effect on the body's own digestive enzymes, perhaps reducing the stress on on the pancreas and allowing the body to redirect energy to other areas.
Pancreatic enzymes and protease enzyme preparations have been shown to be useful in the treatment of many acute and chronic inflammatory conditions including sports injuries, tendinitis, and rheumatoid arthritis.
www.totaldiscountvitamins.com /merchant/enzsupplement.htm   (1946 words)

  
 Pancreatic cancer information - National Foundation for Cancer Research
The vast majority of pancreatic cells function as exocrine glands and ducts.
The exocrine ducts carry the pancreatic juice to the small intestine, via the common bile duct.
Exocrine pancreatic cancers (referred to as pancreatic cancer in the remainder of this pamphlet) are usually treated according to the stage of the cancer rather than the exact type.
www2.nfcr.org /site/PageServer?pagename=cancers_pancreatic   (472 words)

  
 pancreatic juice. The Columbia Encyclopedia, Sixth Edition. 2001-05
The juice contains a number of important digestive enzymes, including trypsin, chymotrypsin, carboxypeptidase, lipase, and amylase.
Pancreatic juice is alkaline in nature because of a high concentration of bicarbonate ions; this helps to neutralize the acidic gastric juice from the stomach.
Secretion of pancreatic juice is stimulated by hormones of the duodenum, such as secretin and cholecystokinin, and by nervous impulses through the vagus nerve.
www.bartleby.com /65/pa/pancreat.html   (132 words)

  
 pancreatic juice - HighBeam Encyclopedia
pancreatic juice, secretions of the exocrine portion of the pancreas into the small intestine.
Inhibitory effects of aloe carboxypeptidase fraction on streptozotocin-induced enhancement of vascular permeability in the pancreatic islets.
Pancreatic cancer--family ties: through family studies, scientists have been able to pinpoint where in the genetic makeup--sometimes down to the specific gene and its location on a specific chromosome--the inherited problem originates.
www.encyclopedia.com /doc/1E1-pancreat.html   (511 words)

  
 Scientists develop screening method for pancreatic cancer
The Liverpool-based study group known as EUROPAC (European Registry Of Hereditary Pancreatitis And Familial Pancreatic Cancer), working in collaboration with a similar group in Germany, has shown that familial pancreatic cancer develops at an increasingly younger age as it is passed down generations - a phenomenon known as anticipation.
In the largest study of its kind, the team surveyed 600 families with a history of pancreatic cancer and identified a subgroup of over 80 families whose lifetime risk of developing the cancer was 50 per cent.
Dr Greenhalf added: "Our research has provided strong evidence that anticipation and pancreatic juice analysis are the most effective means of screening for pancreatic cancer in families with a history of the disease.
www.eurekalert.org /pub_releases/2005-09/uol-sds092005.php   (493 words)

  
 Hepatobiliary/GI Application Tips: Secretin Magnetic Resonance Cholangiopancreatography (MRCP)
Assessment of pancreatic exocrine function is important in the diagnosis, management and pre-operative planning of patients with chronic pancreatitis.
In addition, the extent of positive duodenal contrast induced by the drainage of pancreatic fluid via the ampulla can be assessed semi-quantitatively and may be used for the noninvasive evaluation of the exocrine function of the pancreas.
Pancreatic exocrine function is considered to be reduced when the duodenal filling volume grade is less than grade 3.
www.med.nyu.edu /mri/gi/app_tips_secretin.html   (915 words)

  
 Exocrine Secretions of the Pancreas
The enzyme that performs this hydrolysis is pancreatic lipase, which is delivered into the lumen of the gut as a constituent of pancreatic juice.
The major source of amylase in all species is pancreatic secretions, although amylase is also present in saliva of some animals, including humans.
In pancreatic duct cells, the bicarbonate is secreted into the lumen of the duct and hence into pancreatic juice.
arbl.cvmbs.colostate.edu /hbooks/pathphys/digestion/pancreas/exocrine.html   (693 words)

  
 Pancreatic Enzymes :: Holistic Healing :: Functional Foods/Nutraceuticals :: S-Z   (Site not responding. Last check: 2007-10-17)
In this juice are enzymes—including lipases, proteases and amylases—required for the digestion and absorption of food.
Insufficient output of pancreatic enzymes is associated with abdominal bloating and discomfort, gas, indigestion and the passing of undigested food in the stool.
Mild pancreatic insufficiency is thought to be a relatively common condition, especially in the elderly.
www.alive.com /8a1a2.php?subject_bread_cramb=729   (1020 words)

  
 HOW TO FEED A PANCREATIC INSUFFFICIENT DOG ?
The pancreas is an organ close to the liver and the small intestine, whose role (among others) is to produce the pancreatic juice, very rich in various enzymes.
Whatever the cause could be, the result of a pancreatic insufficiency is always the same: a global deficit in pancreatic juice, inducing clinical signs of poor digestive assimilation.
To compensate for the alcalinizing role of the pancreatic juice in the duodenum, an anti-acid treatment is sometimes advised, to improve the efficiency of the pancreatic extracts.
www.petngarden.com /dogs/dogs43.php   (688 words)

  
 Identification of K-ras Mutations in Pancreatic Juice in the Early Diagnosis of Pancreatic Cancer -- Berthelemy et al. ...
Identification of K-ras Mutations in Pancreatic Juice in the Early Diagnosis of Pancreatic Cancer -- Berthelemy et al.
Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma.
Detection of K-ras mutations in the stool of patients with adenocarcinoma and pancreatic duct hyperplasia.
www.annals.org /cgi/content/full/123/3/188   (2354 words)

  
 Exocrine Pancreatic Insufficiency
There are two components to pancreatic juice: the enzyme component and the _______________.
Ingesta in the duodenum stimulates the _______________ cells to release _______________, which leads to an increase in the flow of the enzyme component of the pancreatic juice.
Alkaline fluid is the other part of pancreatic juice and the major anion is bicarb.
www.vin.com /vin_ce/abvp/html/exocrine_pancreatic_insufficiency.html   (862 words)

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