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Topic: Papillomavirus


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  STD Facts - Human papillomavirus (HPV)
Genital HPV infection is a sexually transmitted disease (STD) that is caused by human papillomavirus (HPV).
Human papillomavirus is the name of a group of viruses that includes more than 100 different strains or types.
More than 30 of these viruses are sexually transmitted, and they can infect the genital area of men and women including the skin of the penis, vulva (area outside the vagina), or anus, and the linings of the vagina, cervix, or rectum.
www.cdc.gov /std/HPV/STDFact-HPV.htm   (1185 words)

  
  Cutaneous Manifestations of Human Papilloma Virus
Human papillomavirus types 6 and 11 are the most prevalent viral types found in condyloma acuminata (Figure 7a, 7b, 7c, 7d) [36-39].
The physical state of the human papillomavirus (HPV) genome is usually different in malignant lesions of the skin, in which it is generally found in episomal form, and genital mucosa, in which it is frequently integrated with disruption of the E2 gene.
Human papillomavirus (HPV) 14, 20 and 21 were isolated from the plaques, HPV 3, 14 and 38 from flat warts and HPV 5, 12, 17, 20 and 38 from PV-like lesions.
www.telemedicine.org /warts/cutmanhpv.htm   (17911 words)

  
 ipedia.com: Cervical cancer Article   (Site not responding. Last check: 2007-10-08)
One of the high risk factors for cervical cancer is the presence of antibodies to the human papillomavirus.
One of the high risk factors for cervical cancer is the presence of antibodies to the human papillomavirus (the same group of viruses that cause genital warts).
Although benign, the virus is believed to trigger alterations in the cells of the cervix, leading to the development of cancer.
www.ipedia.com /cervical_cancer.html   (192 words)

  
 News: Human papillomavirus tests could decrease deaths from cervical cancer
‘The gain in life expectancy which we observed with the papillomavirus testing is related to referring patients that test positive for the virus, and are therefore at higher risk of developing cervical cancer, for immediate follow-up investigation at the hospital’ said Rosa Legood, a senior researcher with the Oxford Health Economics Research Centre.
The researchers analyzed data from three laboratories which the Department of Health chose in 2001 as pilot sites for the use of human papillomavirus testing and of Liquid Based Cytology, with which the NHS is gradually replacing the Pap smear.
The paper, entitled ‘Lifetime effects, costs, and cost effectiveness of testing for human papillomavirus to manage low grade cytological abnormalities: modelling study,’ was published in Volume 332, No. 7533, pp 79-85 of the BMJ on 14 January.
www.admin.ox.ac.uk /po/060116.shtml   (601 words)

  
 Harvard Gazette: Papillomavirus' M.O. better understood
Unlike some viruses, such as influenza, HIV, and the common cold virus, which churn out copies within the confines of a single host cell that is then destroyed, human papillomaviruses invade proliferating epithelial cells and distribute their copies among subsequent generations.
Human papillomavirus is a leading cause of sexually transmitted diseases in the United States.
Combined with early methods of detection such as Pap smears, human papillomavirus- specific antivirals could lower the rate of cervical cancer, currently the second most common cancer in women.
www.news.harvard.edu /gazette/2004/05.06/10-papillomavirus.html   (415 words)

  
 Life Cycle Heterogeneity in Animal Models of Human Papillomavirus-Associated Disease -- Peh et al. 76 (20): 10401 -- ...
The human papillomavirus type 16 E5 gene cooperates with the E7 gene to stimulate proliferation of primary cells and increases viral gene expression.
Papillomavirus E7 protein-binding to the retinoblastoma protein is not required for viral induction of warts.
Activation of papillomavirus late gene transcription and genome amplification upon differentiation in semisolid medium is coincident with expression of involucrin and transglutaminase but not keratin-10.
jvi.asm.org /cgi/content/full/76/20/10401   (9891 words)

  
 eMedicine - Papillomavirus : Article by John D Shanley, MD
The major morbidity and mortality related to papillomavirus infections are due to the development of malignancies.
Focal epithelial hyperplasia (Heck disease) is a disseminated papillomavirus infection of the oral mucosa most commonly associated with HPV 32 and HPV 13.
The medications used to treat papillomavirus infections primarily are designed to ablate the lesion because of their corrosive properties.
www.emedicine.com /med/topic1729.htm   (3195 words)

  
 Papillomavirus   (Site not responding. Last check: 2007-10-08)
Many types of papillomavirus cause benign skin tumours (warts) in their natural hosts.
The capsid is composed of 72 morphological units, or capsomers, arranged on the surface of a T=7 icosahedron.
A model of the papillomavirus capsid is shown beside a computer colorized EM image.
web.uct.ac.za /depts/mmi/stannard/papillo.html   (132 words)

  
 papillomavirus --  Britannica Concise Encyclopedia - The online encyclopedia you can trust!
Some types of papillomaviruses that cause genital infections have been linked with various cancerous tumours, especially cervical cancers; their presence can be detected through a Pap smear.
The causes of cervical cancer vary, but most cases are caused by complications associated with human papillomavirus (HPV) infection, a sexually transmitted disease that inhibits the ability of cervical cells to suppress tumours.
The major risk factor for cervical cancer is human papillomavirus infection, which can be reduced or prevented by avoiding sexual contact with individuals who have had multiple sexual partners.
www.britannica.com /ebc/article-9374520?tocId=9374520   (664 words)

  
 Human papillomavirus
Antibodies to human papillomavirus 16 and subsequent in situ or invasive cancer of the cervix.
Genital papillomavirus infection and cervical dysplasia--opportunistic complications of HIV infection.
Sequence variants of human papillomavirus type 16 in clinical samples permit verification and extension of epidemiological studies and construction of a phylogenetic tree.
www.aecom.yu.edu /virus_epi/human_papillomavirus.htm   (16973 words)

  
 The Human Papillomavirus
One of the most common virus groups in the world today affecting the skin and mucosal areas of the body, is the human papillomavirus.
Different types of the human papillomavirus are known to infect different parts of the body.
The human papillomavirus is a double-stranded DNA virus that infects the epithelial cells of skin and mucosa.
www.oralcancerfoundation.org /facts/humanpapillomavirus.htm   (1998 words)

  
 Detection of human papillomavirus infection in squamous tumours of the conjunctiva and lacrimal sac by ...
Detection of human papillomavirus infection in squamous tumours of the conjunctiva and lacrimal sac by immunohistochemistry, in situ hybridisation, and polymerase chain reaction -- Nakamura et al.
Detection of human papillomavirus infection in squamous tumours of the conjunctiva and lacrimal sac by immunohistochemistry, in situ hybridisation, and polymerase chain reaction
Human papillomavirus DNA in tissues and ocular surface swabs of patients with conjuctival epithelial neoplasia.
bjo.bmjjournals.com /cgi/content/full/81/4/308   (2902 words)

  
 [Frontiers in Bioscience 3, d1192-1208, December 1, 1998]   (Site not responding. Last check: 2007-10-08)
Papillomaviruses (genus Papillomavirus of the Papovaviridae family) are associated with cutaneous or mucosal benign and malignant lesions in many species including humans.
Van den Brule, A. Walboomers, M. Du Maine, P. Kenemans and C. Meijer: Difference in prevalence of human papillomavirus genotypes in cytomorphologically normal cervical smears is associated with a history of cervical intra-epithelial neoplasia.
Zhou, J., X. Sun, D. Stenzl and I. Frazer: Expression of vaccinia recombinant HPV 16 L1 and L2 ORF proteins in epithelial cells is sufficient for assembly of HPV virion-like particles.
www.bioscience.org /1998/v3/d/duggan/d1208.htm   (12808 words)

  
 Cell-Mediated Immune Response to Human Papillomavirus Infection -- Scott et al. 8 (2): 209 -- Clinical and Diagnostic ...
T cell proliferative responses against human papillomavirus type 16 E7 oncoprotein are most prominent in cervical intraepithelial neoplasia patients with a persistent viral infection.
Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specific.
Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens.
cdli.asm.org /cgi/content/full/8/2/209   (7853 words)

  
 Human Papillomavirus Infection
Although this virus has been around for centuries, its prevalence is on the rise do to increase promiscuity and advances in birth control allowing the use of condoms to become less necessary.
Human papillomavirus is in actuality a group of over 80 types of the virus.
Some of the strains of this virus cause the warts that might be found on the hands or feet while other strains cause the highly infectious genital wart (2).
sun.science.wayne.edu /~bio340/StudentPages/Damphousse.html   (558 words)

  
 Human Papillomavirus (HPV) Test
A human papillomavirus (HPV) test is done to detect an HPV infection and determine the type of HPV present.
A human papillomavirus (HPV) test is done to check for an HPV infection and find the type of HPV present.
A human papillomavirus (HPV) test is not routinely used to diagnose genital warts.
www.webmd.com /hw/uterine_cervical_cancer/tu6451.asp   (1026 words)

  
 Papillomavirus Research: From Natural History To Vaccines and Beyond
Human papillomavirus is one of the most common causes of sexually transmitted infection in the world and can also cause cancer.
Papillomavirus research has been revolutionised in recent years with the advent of new technologies such as organotypic raft cultures, virus-like particles and transgenic mice.
Essential reading for scientists and researchers working on papillomavirus and a recommended text for anyone involved with antiviral drug and vaccine development.
www.horizonpress.com /hsp/books/pv.html   (594 words)

  
 human papillomavirus on Encyclopedia.com   (Site not responding. Last check: 2007-10-08)
MassARRAY(R) System Offers Significant Improvement in Sensitivity for Detection of Human Papillomavirus.
Human papillomavirus and cervical cancer.(Conference Session Summaries (1))
Use of condoms can reduce duration of HPV infection.(Clinical Rounds)
www.encyclopedia.com /html/h1/human-p.asp   (354 words)

  
 FindArticles search for "Papillomavirus"
Context.-Human papillomavirus (HPV) plays a major role in the etiology of many malignancies of diverse localization, such as uterine cervical carcinoma...
Human papillomavirus (HPV) is the most common sexually transmitted disease in the United States.
HOUSTON -- Diagnosis of human papillomavirus infection in a genital wart should not trigger a rush to judgment regarding recent sexual transgression...
www.findarticles.com /p/search?tb=art&qt=Papillomavirus   (897 words)

  
 NEJM -- Natural History of Cervicovaginal Papillomavirus Infection in Young Women
Influence of age and geographical origin in the prevalence of high risk human papillomavirus in migrant female sex workers in Spain.
Regression of Cervical Intraepithelial Neoplasia and Loss of Human Papillomavirus (HPV) Infection Is Associated with Cell-mediated Immune Responses to an HPV Type 16 E7 Peptide.
Terai, M., Burk, R. Characterization of a novel genital human papillomavirus by overlapping PCR: candHPV86 identified in cervicovaginal cells of a woman with cervical neoplasia.
content.nejm.org /cgi/content/abstract/338/7/423   (4402 words)

  
 Human Papillomavirus (Genital Warts)
Human papillomavirus (HPV) is a group of more than 70 types of viruses that can cause warts (or papillomas).
Although some types of HPV cause common warts on hands and feet, genital HPVs are sexually transmitted and can cause warts in the genital and anal area of both men and women.
About 50% of individuals who are infected with HPV never develop genital warts, but are still capable of transmitting the virus to others.
www.engenderhealth.org /wh/inf/dhp.html   (960 words)

  
 Human Papillomavirus and Cervical Cancer -- Burd 16 (1): 1 -- Clinical Microbiology Reviews
Papillomavirus detection: demographic and behavioral characteristics influencing the identification of cervical disease.
Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation.
Natural variants of the human papillomavirus type 16 E6 protein differ in their abilities to alter keratinocyte differentiation and to induce p53 degradation.
cmr.asm.org /cgi/content/full/16/1/1   (9930 words)

  
 UIHC aids in papillomavirus study - Metro   (Site not responding. Last check: 2007-10-08)
Gardasil was designed to prevent infections from four types of papillomavirus (types 6, 11, 16, and 18).
Papillomavirus 16 and 18 are linked with 70 percent of cervical-cancer cases, and papillomavirus 6 and 11 are connected to 90 percent of all genital-warts cases.
Researchers found that women who received the vaccine were 90 percent less likely to have infections of the four types of papillomavirus.
www.dailyiowan.com /news/2005/04/08/Metro/Uihc-Aids.In.Papillomavirus.Study-917797.shtml   (419 words)

  
 Human Papillomavirus E6-induced Degradation of E6TP1 Is Mediated by E6AP Ubiquitin Ligase -- Gao et al. 62 (11): 3315 ...
Human Papillomavirus E6-induced Degradation of E6TP1 Is Mediated by E6AP Ubiquitin Ligase -- Gao et al.
Thomas M., Banks L. Human papillomavirus (HPV) E6 interactions with Bak are conserved amongst E6 proteins from high and low risk HPV types.
Tong X., Salgia R., Li J. L., Griffin J. D., Howley P. The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase.
cancerres.aacrjournals.org /cgi/content/full/62/11/3315   (5749 words)

  
 Mass Production Of Human Papillomavirus Could Lead To Gains Against Cervical Cancer
Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that enables scientists to mass-produce human papillomavirus (HPV) in the laboratory.
The illustration shows a view of the molecular surface of the atomic model of papillomavirus generated by HHMI investigator Stephen C. Harrison and colleagues.
Mass Production Of Human Papillomavirus Could Lead To Gains Against Cervical Cancer (June 14, 2005) -- HHMI researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that enables scientists to mass-produce human...
www.sciencedaily.com /releases/2005/06/050614002640.htm   (1083 words)

  
 Preventive human papillomavirus vaccination -- Lehtinen and Dillner 78 (1): 4 -- Sexually Transmitted Infections
Prospective seroepidemiological evidence that human papillomavirus type 16 infection is a risk factor for oesophageal squamous cell carcinoma.
Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck.
Conization for cervical intraepithelial neoplasia is followed by disappearance of human papillomavirus deoxyribonucleic acid and a decline in serum and cervical mucus antibodies against human papillomavirus antigensAm J Obstet Gynecol 1996;174:937–42.
sti.bmjjournals.com /cgi/content/full/78/1/4   (2001 words)

  
 High-Risk Human Papillomavirus Is Sexually Transmitted: Evidence from a Follow-Up Study of Virgins Starting Sexual ...
High-Risk Human Papillomavirus Is Sexually Transmitted: Evidence from a Follow-Up Study of Virgins Starting Sexual Activity (Intercourse) -- Krüger Kjaer et al.
Kjaer S. K., van den Brule A. C., Bock J. E., Poll P. A., Engholm G., Sherman M. E., Walboomers J. M., Meijer C. Determinants for genital human papillomavirus (HPV) infection in 1000 randomly chosen young Danish women with normal Pap smear: are there different risk profiles for oncogenic and nononcogenic HPV types?.
Roman A., Fife K. Human papillomavirus DNA associated with foreskins of normal newborns..
cebp.aacrjournals.org /cgi/content/full/10/2/101   (4594 words)

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