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Topic: Paracetamol

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	Paracetamol [www.sopharma.com]
		Paracetamol is metabolized to glucuronides and sulphates in the liver.
		Paracetamol should be given cautiously to patients with a history of alcoholism, acute liver disease, renal insufficiency, hypersensitivity towards drugs, and to asthmatic patient (danger of bronchospasm).
		Paracetamol is applied orally in doses of 0.5-1.0 g, 4 times daily in adults, and 0.5 g, 3 times daily in children.
	www.bpg.bg /sopharma/categories/421/42110paracetamol.html (307 words)

	Medical Dictionary: Paracetamol - WrongDiagnosis.com
		Paldesic Paracetamol Suspension 250mg/5ml, SPC from the eMC
		Paracetamol and Codeine Caplets, SPC from the eMC
		Paldesic Paracetamol Suspension 120mg/5ml, SPC from the eMC
	www.wrongdiagnosis.com /medical/paracetamol.htm (393 words)

	BBC News \| HEALTH \| Paracetamol linked to asthma
		Frequent use of paracetamol was also associated with more severe asthma, and with inflammation of the lining of the nose (rhinitis).
		The authors suggest that frequent use of paracetamol decreases circulating levels of the antioxidant glutathione, high levels of which are found in the lining of the airways and the nose.
		The statement said: "This study suggests that daily use of paracetamol may be linked to a higher possibility of the worsening of asthma symptoms in adults.
	news.bbc.co.uk /1/hi/health/683882.stm (469 words)

	Antidotes for Poisoning by Paracetamol
		Paracetamol hepatotoxicity depends on the metabolic balance between the rate of formation of the toxic arylating metabolite and the rate of glutathione conjugation.
		In animals, experimental stimulation of metabolic activation of paracetamol and glutathione depletion increases toxicity, while, conversely, toxicity is decreased by inhibition of paracetamol oxidation and stimulation of glutathione synthesis.
		The hepatotoxic effect of paracetamol in female mice is reduced by feeding the animals a diet containing 0.75% butylated hydroxyanisol (Miranda et al., 1983), possibly by increasing the concentration of reduced glutathione in the liver (Miranda et al., 1985).
	www.inchem.org /documents/antidote/antidote/ant03.htm (16058 words)

	Paracetamol - Wikipedia, the free encyclopedia
		Paracetamol is also useful in managing more severe pain, allowing lower dosages of additional non-steroidal anti-inflammatory drugs (NSAIDs) or opioid analgesics to be used, thereby minimizing overall side-effects.
		In humans, paracetamol has a narrow therapeutic index – the therapeutic dose is close to the toxic dose.
		Treatment of paracetamol overdose by a veterinarian may involve the use of supportive fluid therapy, acetylcysteine (Mucomyst), methionine or s-adenosyl-l-methionine (SAMe) to slow liver damage and cimetidine (Tagamet) to protect against gastric ulceration.
	en.wikipedia.org /wiki/Paracetamol (4137 words)

	Paracetamol (PIM 396)
		Paracetamol serum concentrations should be based on the treatment nomogram (see Figure 1, Section 1.4, of the Antidotes for poisoning by Paracetamol).
		Although paracetamol does cross the placenta the occasional use of therapeutic doses in healthy women does not seem to be associated with an increased risk of malformation and has not been proved to be teratogenic.
		Once the paracetamol concentration is available, assess the risk of the patient developing toxicity by comparing the plasma paracetamol concentration to the time after ingestion using the treatment nomogram (see Figure 1, Section 1.4, of the Antidotes for poisoning by Paracetamol).
	www.inchem.org /documents/pims/pharm/pim396.htm (2471 words)

	Paracetamol in acute postoperative pain
		Paracetamol is not associated with increased adverse effects in single dose administration.
		With paracetamol 600/650 mg 38% of patients with initial pain of moderate or severe intensity had at least 50% pain relief over 4-6 hours, as did 46% with paracetamol 1000 mg and 65% with paracetamol 1500 mg.
		Adverse effects in studies of paracetamol against placebo were variable, mild and transient and there were no significant differences between paracetamol and placebo for drowsiness/somnolence/sleepiness, dizziness, headache, nausea or vomiting.
	www.jr2.ox.ac.uk /Bandolier/booth/painpag/Acutrev/Analgesics/AP004.html (617 words)

	Paracetamol
		Paracetamol should not be used in hypersensitivity to the preparation and in severe liver diseases.
		The treatment with Paracetamol may change the laboratory tests of uric acid and blood glucose analysis.
		Phenobarbital increases the harming effect of Paracetamol on the liver.
	www.bpg.bg /sopharma/paracetamol.phtml (372 words)

	Panadol
		Paracetamol is about as effective as aspirin at relieving mild to moderate pain and reducing fever, but unlike aspirin it has no anti-inflammatory effect.
		Paracetamol can be used to relieve mild to moderate pain associated with conditions such as headaches, migraine, toothache, teething, colds and flu.
		Paracetamol tablets, capsules, caplets, soluble tablets, suspension and suppositories are also widely available without brand names, ie as the generic medicine.
	www.netdoctor.co.uk /medicines/100003607.html (955 words)

	Interested in Paracetamol?
		Paracetamol under from gastrointestinal within tract the normal is complete comp paracetamol state absorption 2 hours circumstances..
		Avoid paracetamol in adverse paracetamol overdose outcomes ingestion..Due of neonatal to different clearance from paracetamol adverse effects metabolic is paracetamol immaturity, adults..
		This the outcome with infection, paracetamol confounded not pneumonia the that secondary tract in because these such later urinary infections, the of course occurrence as appear is suggests by or poor usually the relationship of disease.
	parryonline.sitesled.com (6903 words)

	Paracetamol
		Paracetamol, is by far the leader, however the Compound Analgesics are catching up, after that Tricyclic antidepressants, Ibuprofen, Opioids, Benzodiazepines and Barbiturates.
		Paracetamol is metabolised in the liver by Cytochromes P450, with a percentage metabolised into toxic intermediates.
		She had a history of overdose with a previous attempt at 14 years old, and was on Fluoxetine, however her GP was in the process of changing her prescription and she had been without medication for about three days.
	www.rcsed.ac.uk /fellows/bcpaterson/new_page_4.htm (1448 words)

	PharmWeb - Paracetamol Information Centre
		Paracetamol has been in use as an analgesic for home medication for over 30 years and is accepted as a very effective treatment for the relief of pain and fever in adults and children.
		Heavy paracetamol use in late pregnancy and wheezing in children
		Paracetamol - metabolism, biochemistry of overdose and its treatment
	www.pharmweb.net /pwmirror/pwy/paracetamol/pharmwebpic.html (217 words)

	Paracetamol - Patient UK
		For example, if a child is taking antibiotics for an ear infection, keep giving paracetamol as well until the pain and fever ease.
		Be careful not to take too much paracetamol by taking paracetamol tablets or liquids in addition to other remedies that already contain paracetamol.
		Another option is to use soluble paracetamol mixed with a drink.
	www.patient.co.uk /showdoc.asp?doc=23068798 (475 words)

	Paracetamol in osteoarthritis of the knee -- Miceli-Richard et al. 63 (8): 923 -- Annals of the Rheumatic Diseases
		Paracetamol in osteoarthritis of the knee -- Miceli-Richard et al.
		paracetamol and placebo in outpatients with OA of the knee,
		paracetamol group and 20 mm for the placebo group.
	ard.bmjjournals.com /cgi/content/full/63/8/923 (4464 words)

	Health Report - 4/10/99: Painkillers
		But for pain relief, you also have the choice of paracetamol, sightly less effective but easier on your stomach, and ibuprofen, sold here as nurofen or actiprofen, for example.
		The patients had common complaints like a sore back or a cold, and were given either aspirin, paracetamol of ibuprofen at random.
		We had expected ibuprofen to be somewhere in between paracetamol and aspirin, probably very close to paracetamol.
	www.abc.net.au /rn/talks/8.30/helthrpt/stories/s57298.htm (1117 words)

	Paracetamol - Health Misc Shopping at dooyoo.co.uk
		The ones that I bought were Tescos Paracetamol Plus at a cost of 39p.
		Paracetamol is an analgesic, pain reliever and antipyretic (reduces temperature).
		It states that it is fast and effective pain relief and is an easy to swallow shape as it is in caplets shape.
	www.dooyoo.co.uk /health-misc/paracetamol (237 words)

	Key questions concerning paracetamol and NSAIDs for osteoarthritis -- Courtney and Doherty 61 (9): 767 -- Annals of the ...
		paracetamol, and placebo has not been reported in the same population.
		In patients with renal impairment, paracetamol is the
		Paracetamol has not been linked to acute bronchospasm.
	ard.bmj.com /cgi/content/full/61/9/767 (4728 words)

	UK legislation on analgesic packs: before and after study of long term effect on poisonings -- Hawton et al. 329 ...
		Effects of legislation restricting pack sizes of paracetamol and salicylates on self poisoning in the United Kingdom: before and after study.
		Paracetamol pack size restriction: the impact on paracetamol poisoning and over-the-counter supply of paracetamol, aspirin and ibuprofen.
		Paracetamol availability and recent changes in paracetamol poisoning: is the 1998 legislation limiting availability of paracetamol being followed?
	bmj.bmjjournals.com /cgi/content/abridged/329/7474/1076 (2010 words)

	Paracetamol
		Standard medical advice is to suppress all fevers with Calpol (paracetamol) or Ibuprofen.
		This is not very helpful when fever is a useful response to infection with a virus or bacterium and runs contrary to the body’s natural attempts to throw out toxins and right itself.
		In 1996 alone, 74,000 cases of acetaminophen toxicity were reported in the United States, according to United States Poison Control Centers figures.
	www.whale.to /drugs/paracetamol1.html (508 words)

	Paracetamol toxicity: epidemiology, prevention and costs to the health-care system -- SHEEN et al. 95 (9): 609 -- QJM
		Paracetamol overdose is a significant cause of hospital admission,
		Hein A, Jakobsson J, Ryberg G. Paracetamol 1 g given rectally at the end of minor gynaecological surgery is not efficacious in reducing postoperative pain.
		Ragg P, Davidson A. Comparison of the efficacy of paracetamol versus paracetamol, codeine and promethazine (Painstop) for premedication and analgesia for myringotomy in children.
	qjmed.oxfordjournals.org /cgi/content/full/95/9/609 (5717 words)

	Buy Paracetamol Onlline : Paracetamol Forum
		Paracetamol addition, there is also a standalone Corporate Edition version, which is aimed to a centrally managed corporate environment.
		It is called Symantec AntiVirus Corporate Paracetamol and has different features Paracetamol present Paracetamol the traditional retail version of Paracetamol software.
		Paracetamol versions of Norton AntiVirus were integrated and took much from Paracetamol Point Paracetamol (CPAV), which was acquired by Paracetamol in 1994.
	www.progsearch.org /tableto4ki/paracetamol.html (254 words)

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