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Topic: Parietal cell

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List of distinct cell types in the adult human body

Gastric acid

Digestive fluid

Intrinsic factor

Mast cell

Histamine

Proton pump inhibitor

Gastrin

Stomach

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Mitochondrion

Somatostatin

Antihistamine

Digestive system

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	The Parietal Cell: Mechanism of Acid Secretion
		As a consequence, the parietal cell and the mechanisms it uses to secrete acid have been studied extensively, leading to development of several drugs useful for suppressing acid secretion.
		Histamine from enterochromaffin-like cells may well be the primary modulator, but the magnitude of the stimulus appears to result from a complex additive or multiplicative interaction of signals of each type.
		Histamine's effect on the parietal cell is to activate adenylate cyclase, leading to elevation of intracellular cyclic AMP concentrations and activation of protein kinase A (PKA).
	arbl.cvmbs.colostate.edu /hbooks/pathphys/digestion/stomach/parietal.html (853 words)

	ScienceDaily: Parietal cell (Site not responding. Last check: 2007-10-28)
		Parietal cells (also called oxyntic cells) are the stomach epithelium cells which secrete gastric acid.
		Parietal cells contain an extensive secretory network (called canaliculi) from which the HCl is secreted by active transport into the stomach.
		Cells of the stomach -- Parietal cells (also called oxyntic cells) are the stomach epithelium cells which secrete gastric acid.
	www.sciencedaily.com /encyclopedia/Parietal_cell (1464 words)

	Heartburn, GERD and Acid Reflux help. Learn about acid reflux symptoms and the causes for heartburn as well as new ...
		There's a cell in the stomach called a parietal cell, and that parietal cell makes acid.
		H2 blockers simply block prevent histamine from stimulating the parietal cell, thus reducing the amount of acid that's made.
		Parietal cells in the stomach secrete acid, and the part of the parietal cell that does that is called the proton pump.
	www.helpheartburn.com /heartburn/articles/xml_heartburnprevent.asp (1439 words)

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	Body Part - Parietal cell
		Gastric glands are simple branched tubular glands located in the lamina propia of the cardia, fundus and pylorus.
		Parietal (oxyntic) cells are concentrated in the upper half of the gastric glands.
		Parietal cells possess a unique intracellular tubulovesicular system, many mitochondria and secretory intracellular canaliculi (deep invaginations of the apical plasma membrane) lined by microvilli.
	www.bioeng.auckland.ac.nz /anatml/anatml/database/cells/cells/parts/part/part_36.html (235 words)

	ScienceDaily: Help Page (Site not responding. Last check: 2007-10-28)
		Enzyme Inhibitor Produces Stable Disease In Patients With Advanced Solid Cell Cancers (November 15, 2006) -- Preliminary trials of a MEK enzyme inhibitor have shown that it is capable of producing long-lasting stable disease in patients with advanced solid cancers.
		Gene Silencing Technology Is Quietly Moving Toward The Clinic (November 15, 2006) -- The gene silencing technology showcased in the 2006 Nobel Prize in Physiology or Medicine is on an amazingly fast track toward use in treating a variety of serious diseases, according to an article...
		Adult Pig Stem Cells Show Promise In Repairing Animals' Heart Attack Damage (November 14, 2006) -- Johns Hopkins scientists have successfully grown large numbers of stem cells taken from adult pigs' healthy heart tissue and used the cells to repair some of the tissue damage done to those organs by...
	www.sciencedaily.com /articles/plants_animals/cell_biology (1165 words)

	Specialty Laboratories ::: we help doctors help patients
		EIA is said to be 82% sensitive and 90% specific for parietal cell autoantibodies.
		Oya H, Uchida Y, Morshed SA, Nishioka M. Anti-parietal cell antibody in autoimmune liver diseases is associated with gastric mucosal atrophy and intestinal metaplasia.
		Carmel R. Reassessment of the relative prevalence of antibodies to gastric parietal cell and to intrinsic factor in patients with pernicious anaemia: influence of age and race.
	www.specialtylabs.com /books/display.asp?id=263 (398 words)

	Parietal Cell Antibody, IgG
		Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
		Most patients with pernicious anemia have parietal cell antibodies.
		However, the fact that such antibodies are found with increased frequency in unaffected family members, as well as in patients with other autoimmune diseases, suggests these antibodies do not cause disease by themselves.
	www.aruplab.com /guides/ug/tests/0050596.jsp (79 words)

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