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Topic: Pemphigus


In the News (Mon 6 Oct 08)

  
  Pemphigus
Pemphigus is a rare autoimmune blistering disorder of the skin.
Pemphigus vulgaris is produce by antibodies in the blood that attack the skin directly.
Pemphigus vulgaris usually starts in middle-aged and older adults, but is can occur at any age.
www.aocd.org /skin/dermatologic_diseases/pemphigus.html   (713 words)

  
  P - Pemphigus
Pemphigus foliaceus, pemphigus vulgaris, pemphigus erythematosus and pemphigus vegetans There are several related immune mediated skin disorders called pemphigus complex.
Pemphigus erythematosus is second most common and may just be a milder form of pemphigus foliaceus.
Treatment of pemphigus erythematosus and pemphigus vegetans may not be necessary or is usually possible with topical corticosteroids or low to medium dosages of prednisone.
www.vetinfo.com /dencyclopedia/depemphigus.html   (629 words)

  
 MedlinePlus Medical Encyclopedia: Pemphigus vulgaris
Pemphigus vulgaris is an autoimmune skin disorder characterized by blistering of the skin and mucous membrane.
Pemphigus involves blistering of the outer (epidermal) layer of the skin and mucous membranes.
Pemphigus may be a side effect of certain blood pressure medications (ACE inhibitors) or chelating agents (medications, such as penicillamine, that remove certain materials from the blood).
www.nlm.nih.gov /medlineplus/ency/article/000882.htm   (653 words)

  
 pemphigus - British Association of Dermatologists
Pemphigus vulgaris is a rare autoimmune (see below) disease that causes severe blistering of the skin and of the mucous membranes lining the mouth, nose, throat and genitals.
This causes the blisters and erosions that are typical of pemphigus vulgaris.
Pemphigus vulgaris is not an infection: it cannot be caught or passed on to anyone else.
www.bad.org.uk /patients/leaflets/pemphigus.asp   (1278 words)

  
 Pemphigus Vulgaris - Health Encyclopedia
Pemphigus vulgaris is an autoimmune skin disorder characterized by blistering of the skin and mucous membrane.
Pemphigus involves blistering of the outer (epidermal) layer of the skin and mucous membranes.
Pemphigus may be a side effect of certain blood pressure medications (ACE inhibitors) or chelating agents (medications, such as penicillamine, that remove certain materials from the blood).
www.nbc4.com /encyclopedia/6861143/detail.html   (793 words)

  
 Pemphigus Research   (Site not responding. Last check: )
Pemphigus is a term used to describe blistering of the skin caused by binding of antibodies to the surface of the cells of the outer layer of the skin, the epidermis.
In pemphigus vulgaris, the most common form of pemphigus, there are IgG antibodies that bind to the cell surfaces of epidermis of the skin as well as the epithelium lining mucosal surfaces such as the mouth.
Paraneoplastic pemphigus is a recently-described autoimmune blistering disease that occurs in patients with certain types of cancers.
www.hopkinsmedicine.org /pemphigus/types.html   (1071 words)

  
 Pemphigus vegetans
Although the antigens reactive with sera from PVg and pemphigus vulgaris were the same, strong fixation of complement by PVg antibodies, due to the presence of complement-dependent IgG subclasses, and subsequent in situ activation of complement, might explain the marked infiltration of neutrophils and eosinophils in PVg.
Pemphigus vegetans, a rare variant of pemphigus, is manifested by vegetating plaques, usually in intertriginous areas of patients who probably have an increased resistance to the disease.
Pemphigus vegetans is a rare variant of pemphigus vulgaris and is characterized by flaccid bullae, which become eroded and form vegetations or papillomatous proliferations, especially in the intertriginous areas.
www.thedoctorsdoctor.com /diseases/pemphigus_vegetans.htm   (1275 words)

  
 Pemphigus Vulgaris - WrongDiagnosis.com
Pemphigus is a group of autoimmune diseases involving the formation of fluid-filled blisters.
Pemphigus vulgaris is a severe and often fatal form of pemphigus and occurs mostly in people aged between 40 and 60.
Pemphigus Vulgaris is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
www.wrongdiagnosis.com /p/pemphigus_vulgaris/intro.htm   (394 words)

  
 Pemphigus
Pemphigus is a group of rare skin disorders that cause blisters of your skin or mucous membranes, such as in your mouth or on your genitals.
Pemphigus usually occurs in people between the ages of 30 and 60, but it also can affect children and older adults.
The mortality rate for this type of pemphigus is estimated to be 90 percent, independent of the underlying cancer.
www.cnn.com /HEALTH/library/DS/00749.html   (1172 words)

  
 Pemphigus vegetans in a patient with lung cancer
The incidence of neoplasms in patients with pemphigus is from 5 to 12 percent of the total of pemphigus cases and is significantly greater than in controls or than chance expectation [5, 6, 7].
It has been suggested that radiotherapy can be a provoking factor for the development of pemphigus in patients with malignancy by inducing a severe immunosuppression, by altering the antigenicity of the keratinocyte surface, or by unmasking epidermal antigens [7, 9].
In previously described cases of pemphigus induced by radiotherapy the threshold dose was about 40 Gy (38-100 Gy); the initial site of pemphigus was exclusively limited to that of the irradiation, and the time interval between the radiotherapy and the onset of pemphigus was usually short—several days to several weeks [9].
dermatology.cdlib.org /111/case_reports/pemphigus/serwin.html   (1356 words)

  
 About Pemphigus - International Pemphigus Foundation   (Site not responding. Last check: )
Pemphigus is a group of rare autoimmune blistering diseases of the skin and/or mucous membranes.
There are several types of Pemphigus, and early diagnosis is important.
Treatment is available, as is help for living with Pemphigus, including information on nutrition and caregiving.
www.pemphigus.org /whatisgus.html   (213 words)

  
 Pemphigus vulgaris
Pemphigus vulgaris is an autoimmune or "self-allergy" disease in which a patient’s own circulating antibodies become altered so that they attack the points of adhesion of the epithelial cells, one to another, of the skin and mucous membranes.
Pemphigus vulgaris is a disease of older individuals, usually 50 years or older, but rare examples in children and adolescents have been reported.
Patients with paraneoplastic pemphigus may have to forgo treatment of their vesiculobullous disease until the underlying neoplasm is controlled, although supportive therapy can be instituted.
www.maxillofacialcenter.com /BondBook/mucosa/pv.html   (1547 words)

  
 S6C2-Pemphigus
The pemphigus disorders are characterized by a disruption of the cohesive structures that bind particular squamous epithelial cells to their neighbors.
Pemphigus is a disease of squamous epithelium; more specifically, the initial site of damage is at the level of desmosomes.
Pemphigus vegetans is characterized by epidermal hyperplasia with elongated, coarsened rete ridges.
www.som.tulane.edu /classware/pathology/medical_pathology/InflamDermato/S6C2Pemphigus/s6c2pemphigus.html   (1211 words)

  
 Pemphigus
Pemphigus is a group of chronic autoimmune skin diseases with blister formations in the outer layer of the skin and mucous membranes.
Pemphigus vulgaris begins with blister formations (bullae) occurring in the mouth and on the scalp.
Pemphigus vulgaris predominately occurs in middle-aged patients of Jewish or Mediterranean descent.
www.medical-library.net /sites/pemphigus.html   (313 words)

  
 Cyclophosphamide pulses with oral prednisolone in the treatment of pemphigus: A pilot study
Pemphigus is a potentially fatal disease, associated with a mortality rate as high as 90-100 percent when untreated [1].
In comparison, Ratnam et al.[12] achieved initial control of pemphigus with daily steroids in low-dose (45-60 mg/day) and high-dose (120-150 mg/day) regimens, at a mean of 24 days and 19.6 days respectively in these two groups.
Untreated pemphigus carried a high mortality rate, but this was brought down with the advent of steroid therapy [1].
dermatology.cdlib.org /113/original/pemphigus-cytoxan/bhat.html   (3287 words)

  
 Pemphigus erythematosus
Desmoplakin I and II in acantholytic dermatoses: preservation in pemphigus vulgaris and pemphigus erythematosus and dissolution in Hailey-Hailey's disease and Darier's disease.
The histology is identical to pemphigus foliaceus with a subcorneal blister with acantholysis.
They differ in that pemphigus erythematosus is limited in distribution and usually has concomitant basement membrane zone deposition of immunoglobulin and complement in lesional skin in addition to intercellular space staining in the epidermis, whereas pemphigus foliaceus is a generalized process that reputedly lacks basement membrane zone staining.
www.thedoctorsdoctor.com /diseases/pemphigus_erythematosus.htm   (1675 words)

  
 BBC - Health - Conditions - Pemphigoid and pemphigus
In the case of pemphigus it's the skin cells and often those of the mucosal membranes (the inside of the mouth, for example) that come under attack.
Pemphigus foliaceus - blisters don't occur in the mouth and those on the skin are more itchy than painful.
Pemphigus can run in families and although its precise cause is unknown a number of possible triggers have been identified.
www.bbc.co.uk /health/conditions/pemphigoid1.shtml   (587 words)

  
 Pemphigus
Pemphigus is a disease that results when the body's immune defenses attack its own skin.
Actually, Pemphigus is a complex of diseases differentiated by the skin layer which is attacked.
Pemphigus Erythematosus is similar but involves the outer skin layer or stratum corneum.
www.akitaclub.org /health/health/pemphigus1.html   (1706 words)

  
 Children's Skin Disease Foundation: Pemphigus Foliaceus
Pemphigus is not pemphigoid, cicatricial pemphigoid or benign familial pemphigus, also known as Hailey-Hailey disease.
To date, definitive statistics on the incidence and prevalence of pemphigus are not available, but estimates of the number of new cases diagnosed each year ranges from as high as 5 per one hundred thousand to as low as one per million, depending upon the type of pemphigus and the ethnicity of the affected population.
Pemphigus is frequently the last disease considered during diagnosis.
www.csdf.org /skin/pf.htm   (1129 words)

  
 Pemphigus
When I was first diagnosed in 1995, I set a goal to be Pemphigus free by 2003 (seven years).
In February, 2003, pemphigus was officially removed from my medical chart by my primary care physician.
Please read through this web and visit the Pemphigus Foundation, where you will get a more traditional view of pemphigus and the drugs that may be useful to treat it.
www.uoregon.edu /~sshapiro/Pemphigus/TableOfContents.html   (444 words)

  
 Immune Problems - Pemphigus
Early in pemphigus foliaceus the disease may be confined to the head and feet, making it hard to distinquish from pemphigus erythematosus.
Pemphigus foliaceus is the most common form of pemphigus in dogs and cats.
If your dog has pemphigus vulgaris, it is probably unlikely that you will be able to reduce the dosage of prednisone and maintain control of the pemphigus.
www.vetinfo4dogs.com /dpemph.html   (1978 words)

  
 pemphigus
Pemphigus ontstaat door een autoimmuun reactie, dat is een reactie van het lichaam tegen het eigen weefsel.
Bij pemphigus is deze reactie gericht tegen bepaalde bestanddelen van de opperhuid, waardoor de opperhuid plaatselijk loslaat en blaren gaat vormen.
Als pemphigus vulgaris onbehandeld wordt gelaten is het een levensbedreigende aandoening, pemphigus foliaceus heeft onbehandeld een veel gunstiger beloop.
www.huidinfo.nl /pemphig.html   (300 words)

  
 Pemphigus is a group of rare autoimmune skin disorders characterized by the development of blisters in the outer layer ...
Pemphigus is a group of rare autoimmune skin disorders characterized by the development of blisters in the outer layer of the skin
Pemphigus Vulgaris is the most common form and may begin with isolated blisters on the scalp, and then in the mouth.
Pemphigus affects males and females in equal numbers and is most common in middle-aged and elderly people.
www.cidpusa.org /pemphigus.htm   (2010 words)

  
 Pemphigus Foliaceus - VeterinaryPartner.com - a VIN company!
The pemphigus complex is a group immune-mediated skin diseases involving inappropriate immunological attack against one of the normal layers of the skin.
Pemphigus foliaceus is the most common immune-mediated skin disease of dogs and cats.
Pemphigus foliaceus is usually spontaneous but can also be drug induced or can result as a reaction to years of chronic skin disease.
www.veterinarypartner.com /Content.plx?P=A&A=2202   (965 words)

  
 Arizona Adopt A Greyhound
While it is, of course, possible to get secondary infections in unhealthy pemphigus nails, you cannot resolve the problem without treating the underlying autoimmune disorder.
Common sense will tell you that culturing a nail as a means of diagnosis is quite likely to yield any number of cooties as greyhounds use their nails to walk across the (unsterile) ground.
The appearance/course of pemphigus in greyhounds is so classic that I feel it's a real waste of time/money, not to mention unnecessary pain and disfigurement for the poor greyhound, to go through this in the name of proving a diagnosis.
www.arizonaadoptagreyhound.org /newsletter/articles/toenails.html   (729 words)

  
 Pemphigus Vulgaris - Patient UK
Pemphigus vulgaris is a serious skin disease that causes blisters.
Pemphigus vulgaris is a skin condition that causes blisters.
PV is the most common form of pemphigus and one of the most serious blistering skin conditions.
www.patient.co.uk /showdoc.asp?doc=23069058   (1588 words)

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