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Topic: Pemphigus vulgaris

	Pemphigus - Wikipedia, the free encyclopedia
		Pemphigus is an autoimmune disorder that causes blistering and raw sores on skin and mucous membranes.
		Pemphigus foliaceus is characterized by crusty sores that often begin on the scalp, and may move to the chest, back, and face.
		It is not as painful as pemphigus vulgaris, and is often mis-diagnosed as dermatitis or eczema.
	en.wikipedia.org /wiki/Pemphigus (594 words)

	P - Pemphigus
		Pemphigus foliaceus, pemphigus vulgaris, pemphigus erythematosus and pemphigus vegetans There are several related immune mediated skin disorders called pemphigus complex.
		Pemphigus vegetans may be a less severe form of pemphigus vulgaris but it does look different.
		Treatment of pemphigus erythematosus and pemphigus vegetans may not be necessary or is usually possible with topical corticosteroids or low to medium dosages of prednisone.
	www.vetinfo.com /dencyclopedia/depemphigus.html (629 words)

	Pemphigus vulgaris
		Background: Autoimmune blistering diseases, pemphigus vulgaris (PV) and pemphigus foliaceus (PF), are known to be caused by binding of autoantibodies to the desmosomal cadherins, desmoglein 3 and desmoglein 1, respectively.
		Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are characterized by autoantibodies to the desmosomal glycoproteins desmoglein 3 (Dsg 3) and Dsg 1 (Dsg 1), respectively.
		Pemphigus vulgaris is an autoimmune blistering disease characterized by disseminated bullae and erosions of the mucosal surfaces and skin.
	www.thedoctorsdoctor.com /diseases/pemphigus_vulgaris.htm (8427 words)

	MedlinePlus Medical Encyclopedia: Pemphigus vulgaris
		Pemphigus vulgaris is an autoimmune skin disorder characterized by blistering of the skin and mucous membrane.
		Pemphigus involves blistering of the outer (epidermal) layer of the skin and mucous membranes.
		Pemphigus may be a side effect of ACE inhibitors (such as Elanapril) or chelating agents (such as penicillamine).
	www.nlm.nih.gov /medlineplus/ency/article/000882.htm (654 words)

	Pemphigus Vulgaris Network
		Pemphigus Vulgaris (PV) is one of a group of rare, relapsing auto-immune diseases causing blistering of the skin and mucous membranes (eg mouth, nose, throat and genitals).
		The Pemphigus Vulgaris Network is a voluntary, not-for-profit, group started in 1997 to provide information and support for people living with pemphigus and their relatives, friends and carers.
		For example, pemphigus foliaceus may be treated primarily with topical steroids and a lower dose of oral steroids whereas pemphigus vulgaris is frequently treated with a higher dose of oral steroids.
	www.pemphigus.org.uk (4373 words)

	Pemphigus Vulgaris
		Pemphigus vulgaris (PV): This is the most severe form of pemphigus, and is extremely rare.
		Pemphigus Erythematosus (PE): This is one of the milder forms of the pemphigus conditions.
		Pemphigus Vegitans: Pemphigus vegetans is another of the milder forms of the pemphigus conditions.
	www.shilohgtf.com /Pemphigus%20Vulgaris.htm (744 words)

	pemphigus - British Association of Dermatologists (Site not responding. Last check: 2007-10-31)
		Pemphigus vulgaris is a rare autoimmune (see below) disease that causes severe blistering of the skin and of the mucous membranes lining the mouth, nose, throat and genitals.
		This causes the blisters and erosions that are typical of pemphigus vulgaris.
		Pemphigus vulgaris is not an infection: it cannot be caught or passed on to anyone else.
	www.bad.org.uk /patients/leaflets/pemphigus.asp (1278 words)

	Pemphigus
		Pemphigus is a rare autoimmune blistering disorder of the skin.
		Pemphigus vulgaris is produce by antibodies in the blood that attack the skin directly.
		Pemphigus vulgaris usually starts in middle-aged and older adults, but is can occur at any age.
	www.aocd.org /skin/dermatologic_diseases/pemphigus.html (714 words)

	ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Pemphigus vulgaris
		About one-half of the cases of pemphigus vulgaris begin with blisters in the mouth, followed by skin blisters.
		Pemphigus vulgaris - close-up: Pemphigus vulgaris is an autoimmune disorder where the body's immune system attacks some of the proteins in the skin.
		Pemphigus vulgaris is an autoimmine disorder, where the body's immune system attacks some of the proteins in the skin.
	www.enlmedical.com /article/000882.htm (646 words)

	Pemphigus vulgaris with nail involvement presenting with vegetating and verrucous lesions
		Pemphigus vulgaris (PV) is an autoimmune blistering disease, with blisters occurring in the deeper part of the epidermis, above the basal layer.
		Although the presence of pemphigus lesions on the skin of the distal phalanges surrounding the nail is well known, none of the reported nail manifestations of pemphigus have the same warty aspect of our patient [3-13].
		Verrucous and vegetating lesions in pemphigus are usually described in pemphigus vegetans, but they are localized to skin folds and characteristic histological findings include epidermal hyperplasia and eosinophilic abscesses, which were absent in our case [1].
	dermatology.cdlib.org /95/case_reports/pemphigus/mascarenhas.html (1509 words)

	Pemphigus vulgaris
		Pemphigus vulgaris is an autoimmune blistering disease, which basically means that an individual's immune system starts reacting against his or her own tissue.
		In pemphigus vulgaris immunoglobulin type G (IgG) autoantibodies bind to a protein called desmoglein 3, which is found in desmosomes in the keratinocytes near the bottom of the epidermis.
		Systemic corticosteroid therapy is effective in reducing or eliminating the clinical manifestations of pemphigus vulgaris, although doses of prednisone may have to be as high as 400 mg.
	skin-care.health-cares.net /pemphigus-vulgaris.php (618 words)

	Pemphigus vulgaris (Site not responding. Last check: 2007-10-31)
		Pemphigus is a group of chronic autoimmune skin diseases characterized by blister formations in the outer layer of the skin and the mucous membranes.
		Pemphigus vulgaris begins with blisters (bullae) occurring in the mouth and on the scalp.
		Pemphigus vulgaris predominantely occurs in middle-aged patients of Jewish or Mediterranean descent.
	www.orpha.net /static/GB/pemphigus_vulgaris.html (146 words)

	Canine pemphigus vulgaris (Site not responding. Last check: 2007-10-31)
		The histopathologic picture was typical of a pemphigus vulgaris; this disorder was compatible with the signs and lesions observed in the physical examination of the animal, although mucosa lesions were not numerous.
		The diagnosis of pemphigus is based on the history, the physical exploration of the animal and some complementary tests, including direct smears from intact vesicles, and skin biopsy for histopathological examination and for direct immunofluorescence testing (DIT) (Muller and others 1989).
		In addition, according to Tizard (1987) DIT is limited in pemphigus diagnosis because of the difficulties in locating precisely the lesions in the different layers of the epidermis and dermis.
	www.geocities.com /CollegePark/Field/5413/pemphigus.htm (1896 words)

	Pemphigus
		Pemphigus is a group of rare autoimmune skin disorders characterized by the development of blisters in the outer layer of the skin (epidermis) and mucous membranes (thin moist layers that line the body's internal surfaces).
		Pemphigus Vulgaris is the most common form and may begin with isolated blisters on the scalp, and then in the mouth.
		Pemphigus may also occur as a result of an adverse reaction to certain drugs such as d-penicillamine and rifampin; symptoms usually resemble those of Pemphigus Foliaceus rather than Pemphigus Vulgaris.
	hw.healthdialog.com /kbase/nord/nord44.htm (2477 words)

	Pemphigus vulgaris
		Pemphigus vulgaris is an autoimmune or "self-allergy" disease in which a patient’s own circulating antibodies become altered so that they attack the points of adhesion of the epithelial cells, one to another, of the skin and mucous membranes.
		Pemphigus vulgaris is a disease of older individuals, usually 50 years or older, but rare examples in children and adolescents have been reported.
		The associated autoantibodies are different from those of routine pemphigus vulgaris, and can be demonstrated by indirect immunofluorescence using rat bladder transitional epithelium as the substrate.
	www.maxillofacialcenter.com /BondBook/mucosa/pv.html (1547 words)

	Peptimmune Online - Pemphigus Vulgaris
		Pemphigus vulgaris is an autoimmune disorder caused by the formation of auto-antibodies
		pemphigus vulgaris, but there may be a genetic predisposition.
		PI-0824 targets the disease pathogenenis in pemphigus vulgaris and is being developed as peptide immunotherapy.
	www.peptimmune.com /pemphigus.asp (255 words)

	Pemphigus Vulgaris - Patient UK
		Pemphigus vulgaris is a serious skin disease that causes blisters.
		Pemphigus vulgaris is more serious than most other 'blistering' skin conditions.
		Pemphigus vulgaris is a skin condition that causes blisters.
	www.patient.co.uk /showdoc/23069058 (1496 words)

	Immune Problems - Pemphigus (Site not responding. Last check: 2007-10-31)
		Early in pemphigus foliaceus the disease may be confined to the head and feet, making it hard to distinquish from pemphigus erythematosus.
		Pemphigus foliaceus is the most common form of pemphigus in dogs and cats.
		If your dog has pemphigus vulgaris, it is probably unlikely that you will be able to reduce the dosage of prednisone and maintain control of the pemphigus.
	www.vetinfo.com /dpemph.html (1939 words)

	eMedicine - Pemphigus Vulgaris : Article Excerpt by: Bassam Zeina, MD, PhD (Site not responding. Last check: 2007-10-31)
		Pemphigus describes a group of chronic bullous diseases, originally named by Wichman in 1791.
		The term pemphigus refers to a group of autoimmune blistering diseases of the skin and mucous membranes characterized histologically by intradermal blister and immunopathologically by the finding of in vivo bound and circulating immunoglobulin G (IgG) antibody directed against the cell surface of keratinocytes.
		Pemphigus antibody binds to keratinocyte cell surface molecules desmoglein 1 and desmoglein 3.
	www.emedicine.com /derm/byname/pemphigus-vulgaris.htm (555 words)

	PEMPHIGUS VULGARIS: Contact a Family - for families with disabled children: information on rare syndromes and disorders
		Pemphigus vulgaris (PV) is a condition which causes blistering of the outer layer of the skin (epidermis) and mucosal membranes.
		As Pemphigus conditions can give rise to pain in affected individuals, details of sources of information can be found in the Pain Management section on the Helpful Organisations pages.
		The Pemphigus Vulgaris Network is a small network offering support to affected individuals, a forum for affected persons and professionals, contact with others, where possible, and information on the disorder (please send SAE).
	www.cafamily.org.uk /Direct/p16.html (989 words)

	[No title]
		Canine pemphigus vulgaris - The present report describes a case of canine pemphigus vulgaris.
		Pemphigus Vulgaris Pemphigus Vulgaris is the most often seen of the pemphigus diseases, but fortunately is relatively unusual.
		Pemphigus Vulgaris and Homeopathy - Homeopathy - Pemphigus Vulgaris.
	www.diseasedirectory.net /Rare_Disorders/Pemphigus/default.aspx (388 words)

	Diagnostic Patterns in Pemphigus Vulgaris - Medical Article Archive of the International Pemphigus Foundation (Site not responding. Last check: 2007-10-31)
		Pemphigus vulgaris is an autoimmune disorder that typically presents with sores in the mouth (oral), on the skin, or both.
		Answer to question 1-In 30 individuals (81%), the first presentations of pemphigus vulgaris were mouth (oral) sores.
		Answer to question 3-When the skin was the first manifestation of pemphigus vulgaris, most patients were diagnosed by one or two clinicians.
	www.pemphigus.org /am_diagpatterns.html (636 words)

	eMedicine - Pemphigus Vulgaris : Article by Bassam Zeina, MD, PhD (Site not responding. Last check: 2007-10-31)
		Pemphigus in pregnancy: Occurrence in pregnancy is rare.
		Infants with neonatal pemphigus remit with clearance of maternal autoantibodies.
		This pattern of immunoreactants is not specific for PV and may be seen in pemphigus vegetans, pemphigus foliaceus, and pemphigus erythematosus.
	www.emedicine.com /derm/topic319.htm (3989 words)

	[No title] (Site not responding. Last check: 2007-10-31)
		When the pemphigus is controlled I drop the prednisone rapidly to 20 mg, and then taper slowly to zero.
		For Pemphigus foliaceus, I have been less aggressive, perhaps because that condition doesn't seem to be as threatening to the patient as pemphigus vulgaris.
		For pemphigus, you may need to pulse as often as every two weeks but decrease to monthly as other treatments kick in.
	matrix.ucdavis.edu /rxderm-archives/pemphigus-vulgaris (996 words)

	pemphigus vulgaris (Site not responding. Last check: 2007-10-31)
		The clinical presentation and pathology are typical for pemphigus vulgaris.
		Although pemphigus is thought of as an acantholytic disease, there usually is not as much acantholysis of individual cells as is seen in Hailey-Hailey disease (benign chronic familial pemphigus).
		The epidermis in pemphigus vulgaris tends to slough off above the basal layer in a relatively intact fashion though there are individual acantholytic cells.
	www.bweems.com /pvulg.html (261 words)

	Pemphigus Vulgaris - WrongDiagnosis.com
		Pemphigus Vulgaris is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Pemphigus Vulgaris, or a subtype of Pemphigus Vulgaris, affects less than 200,000 people in the US population.
		They list Pemphigus Vulgaris as a "rare disease".
	www.wrongdiagnosis.com /p/pemphigus_vulgaris/intro.htm (229 words)

	Pemphigus vulgaris
		Pemphigus vulgaris is an uncommon, debilitating, potentially fatal skin disorder characterized by intraepidermal bullae that appear on normal appearing skin without surrounding inflammation.
		Pemphigus may be an adverse reaction to thiol groups found in most drugs and the Allium family, which includes garlic, onions and leeks.
		Pemphigus is also associated with pregnancy, and studies have shown increased levels of estradiol and reduced ones of testosterone.
	www.naturdoctor.com /Chapters/Diseases/Pemphigus_vulgaris.html (888 words)

	Pemphigus vulgaris in a patient with Human Immunodeficiency Virus infection (Site not responding. Last check: 2007-10-31)
		Histopathological examination of peri-ulcer tissue was consistent with pemphigus vulgaris.
		A marked deterioration in the oral pemphigus associated with a severe pneumococcal lower respiratory tract infection was treated with deflazacort, and remission of the oral disease was then achieved with deflazacort and azathioprine.
		Conclusion The development of pemphigus in HIV disease is extremely rare and may be the result of HIV-induced immune changes.
	www.hivdent.org /kabst/kabstrpoj1.htm (319 words)

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