
	Where results make sense

Topic: Penciclovir

In the News (Wed 23 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Herpesviruses 2000: Penciclovir
		Penciclovir is a nucleoside deoxyguanosine analog that inhibits the DNA synthesis of herpesviruses.
		Penciclovir triphosphate is now free to insert in the viral DNA as it is being formed in place of the nucleotide guanine and terminate the sequence, thus inhibiting replication of the virus.
		Intravenous penciclovir is not currently licensed as a treatment, but in clinical trials it was found that doses of 5mg per kg every twelve hours was as effective as acyclovir in treating HSV infections.
	www.stanford.edu /group/virus/herpes/2000/herpes2000drug2.html (581 words)

	MedlinePlus Drug Information: Penciclovir Cream
		Penciclovir is used on the lips and faces of adults to treat cold sores caused by herpes simplex virus.
		Penciclovir does not cure herpes infections but decreases pain and itching if applied when the earliest symptoms first appear.
		Penciclovir should only be used on the lips and face.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a697027.html (497 words)

	About Denavir for Recurrent Cold Sores. Facts and Information. (Site not responding. Last check: 2007-11-04)
		Penciclovir is an antiviral medication most commonly used topically for the treatment of recurrent cold sores.
		Penciclovir topical should be applied to cold sore lesions every 2 hours while awake for a period of four days, unless otherwise directed by your doctor.
		Penciclovir topical should be used to treat cold sores on the lips and face only.
	www.search-over.com /herpes/about_denavir.html (698 words)

	[No title]
		Famciclovir and penciclovir were negative in in vitro tests for gene mutations in bacteria (S. typhimurium and E. coli) and unscheduled DNA synthesis in mammalian HeLa 83 cells (at doses up to 10,000 and 5000 mcg/plate, respectively).
		Penciclovir was positive in the L5178Y mouse lymphoma assay for gene mutation/chromosomal aberrations, with and without metabolic activation (1000 mcg/mL).
		Penciclovir caused an increased incidence of micronuclei in mouse bone marrow in vivo when administered intravenously at doses highly toxic to bone marrow (500 mg/kg), but not when administered orally.
	www.best-meds.com /druginfo/famvir_warnings.htm (882 words)

	Penciclovir (Site not responding. Last check: 2007-11-04)
		Penciclovir interferes with the activity of enzymes needed for the replication of viral DNA in cells, thus preventing the virus from multiplying.
		In animal studies, penciclovir given orally was shown to pass into breast milk, and in fact to be present in higher concentrations than those found in the blood.
		While there is no information on whether penciclovir passes into human breast milk after topical application, you should consult your doctor to help you decide whether to discontinue breast feeding (if the drug is determined to be necessary to the mother) or to discontinue the drug.
	www.wholehealthmd.com /refshelf/drugs_view/1,1524,720,00.html (515 words)

	[No title]
		Penciclovir triphosphate has an intracellular half-life of 10 hours in HSV-1-,20 hours in HSV-2- and 7 hours in VZV-infected cells cultured in vitro; however, the clinical significance is unknown.
		Penciclovir Cmax decreased approximately 50% and Tmax was delayed by 1.5 hours when a capsule formulation of famciclovir was administered with food (nutritional content was approximately 910 Kcal and 26% fat).
		Based on cross-study comparisons, mean penciclovir AUC was 40% larger and penciclovir renal clearance was 22% lower after the oral administration of famciclovir in elderly volunteers (n=18, age 65 to 79 years) compared to younger volunteers.
	www.best-meds.com /drugdescription/famvir_clinical.htm (2020 words)

	Denavir - Drugs & Vitamins - Drug Library - DrugDigest
		Penciclovir treats the symptoms of herpes virus infections on the lips or face.
		Penciclovir will not cure herpes infections; it will help the sores heal faster and may help relieve the pain or discomfort.
		Penciclovir skin cream is only for external use on the lips or face; do not use in the eye or inside the mouth.
	www.drugdigest.org /DD/DVH/Uses/0,3915,523\|Denavir,00.html (498 words)

	MedlinePlus Drug Information: Penciclovir (Topical) (Site not responding. Last check: 2007-11-04)
		Topical penciclovir is used to treat the symptoms of herpes simplex virus infections around the mouth (cold sores).
		Although topical penciclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores heal faster.
		Penciclovir is best used as soon as possible after the symptoms of herpes infection (for example, pain, burning, or blisters) begin to appear.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/203495.html (888 words)

	famciclovir - Womens Health and Medical Information on MedicineNet.com
		Instead, famciclovir is converted to penciclovir in the body, and it is the penciclovir that is active against the viruses.
		(Penciclovir also is available as a topical and intravenous medication.) Famciclovir is active against the same viruses as acyclovir but has a longer duration of action.
		Penciclovir, the active metabolite of famciclovir, is excreted mainly by the kidney, and dosages of famciclovir need to be reduced in patients with kidney dysfunction.
	www.medicinenet.com /famciclovir/article.htm (607 words)

	Long-Term Therapy with the Guanine Nucleoside Analog Penciclovir Controls Chronic Duck Hepatitis B Virus Infection In ...
		Penciclovir's lack of toxicity was further confirmed in this study.
		The guanine nucleoside analog penciclovir is active against chronic duck hepatitis B virus infection in vivo.
		Antiviral activities and pharmacokinetics of penciclovir and famciclovir in Pekin ducks chronically infected with duck hepatitis B virus.
	aac.asm.org /cgi/content/full/42/8/2132 (3900 words)

	Famvir - Famvir Side Effects - Famvir Information - Canadian Pharmacy
		Penciclovir is a substituted guanine analogue with potent and selective antiviral activity against varicella zoster virus and other human herpes viruses.
		Penciclovir is in the same class of antiviral drugs as acyclovir, and both are phosphorylated by viral thymidine kinase and then by cellular enzymes to the active triphosphate form in virus-infected cells.
		It is not known whether it (penciclovir) is excreted in human milk, thus, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
	www.rxcanadapharmacy.com /htmfiles/Famvir.asp (2526 words)

	penciclovir topical - Connecticut
		Penciclovir is used topically for the treatment of recurrent cold sores.
		Penciclovir topical may also be used for purposes other than those listed in this medication guide.
		It is not known whether penciclovir topical passes into breast milk.
	www.saintfranciscare.com /19050.cfm (775 words)

	penciclovir topical - [Medication]
		Do not apply penciclovir topical to the inside of the nose or in or near the eyes, as it may cause irritation.
		Penciclovir topical is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby.
		There are no restrictions on food, beverages, or activity during treatment with penciclovir topical, unless otherwise directed by your doctor.
	www.peacehealth.org /kbase/multum/d04054a1.htm (819 words)

	Pharmacokinetic Studies of 2-Amino-9-(3-acetoxymethyl-4-isopropoxycarbonyl-oxybut-1-yl)purine, an Oral Prodrug for the ...
		of SK1899 to penciclovir was oxidation of the intermediate metabolite
		Clarke SE, Harrell AW and Chenery RJ (1995) The role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver.
		Korba BE and Boyd MR (1996) Penciclovir is a selective inhibitor of hepatitis B virus replications in cultured human hepatoblastoma cells.
	dmd.aspetjournals.org /cgi/content/full/29/7/945 (2542 words)

	Penciclovir detail at IndyaPharma (Site not responding. Last check: 2007-11-04)
		Penciclovir is a white to pale yellow solid.
		Measurable penciclovir concentrations were not detected in plasma or urine of healthy male volunteers (n= 12) following single or repeat application of the 1% cream at a dose of 180 mg penciclovir daily (approximately 67 times the estimated usual clinical dose).
		Denavir (penciclovir cream) is indicated for the treatment of recurrent herpes labialis (cold sores) in adults.
	www.indyapharma.com /Penciclovir-detail.htm (1455 words)

	U.S. Pharmacist
		Penciclovir 1% cream, acyclovir 5% ointment, and valcyclovir are prescription antiviral drugs approved by the FDA for the treatment of herpes labialis.
		Penciclovir cream was effective in significantly reducing healing time and relieving pain for patients with documented HSV-1 infections in two separate well-designed clinical studies.
		Topical penciclovir and docosanol are approved for HSV-1 infections in immunocompetent patients, and topical acyclovir is approved for use in immunosuppressed patients with limited HSV-1 or HSV-2 infections.
	www.uspharmacist.com /index.asp?page=ce/2954/default.htm (4938 words)

	Penciclovir Health Web Links (Site not responding. Last check: 2007-11-04)
		Penciclovir - FamilyDoctor.org - Information for consumers in English or Spanish.
		If he had lived to my age he would have repudiated his doctrine." (Friedrich Wilhelm Nietzsche) Penciclovir It is never too late to be what you might have been.
		Anyone who cannot negotiate Chi squares, assess randomi Penciclovir "In literary criticism the critic has no choice but to make over the victim of his attention into something the size and shape of himself." (John Steinbeck, Travels With Charley) He who laughs last didn't get it.
	www.internet-health-directory.com /Pharmacy_Drugs_and_Medications_P_Penciclovir.html (1615 words)

	Intravenous Penciclovir for Treatment of Herpes Simplex Infections in Immunocompromised Patients: Results of a ...
		Penciclovir and acyclovir were provided as vials of freeze-dried powder for reconstitution.
		The lack of penciclovir resistance among the isolates tested appears to be unusual for an immunocompromised patient population,
		Intravenous penciclovir for the treatment of mucocutaneous herpes simplex infection in immunocompromised patients, abstr.
	aac.asm.org /cgi/content/full/43/5/1192 (3952 words)

	PENCICLOVIR (Topical) (Cream) Prescription Drug Information, Cost, Price, Side Effects, and More.
		PENCICLOVIR (Topical) (Cream) is used for the Treatment
		Penciclovir (pen-SYE-kloe-veer) Treats and relieves pain from cold sores.
		Store PENCICLOVIR (Topical) (Cream) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling.
	www.healthdigest.org /PENCICLOVIR-(Topical)-(Cream)_5550_PRO.php (339 words)

	penciclovir topical Information and Resources Online at The Drug Database - Find Useful Articles and Websites on ...
		Penciclovir topical should be applied to cold sore...
		Penciclovir topical may also be used for purposes other than those...
		Topical penciclovir is used to treat the symptoms of herpes simplex virus infections around the mouth...
	www.thedrugdatabase.com /directory/P/penciclovir_topical (483 words)

	Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors -- Ono-Nita et al. ...
		Penciclovir is a potent inhibitor of herpesvirus, varicella-zoster
		Lack of susceptibility of HBV to penciclovir and nevirapine.
		Korba, B.E., and Boyd, M.R. Penciclovir is a selective inhibitor of hepatitis B virus replication in cultured human hepatoblastoma cells.
	www.jci.org /cgi/content/full/103/12/1635 (4458 words)

	Penciclovir Sodium at Absolute Authority :: Penciclovir Sodium Information, Products, Services, Resources ...
		This is your central hub for exploring the world of Penciclovir Sodium.
		If you would like to contribute any articles or resources on Penciclovir Sodium just use the submission form.
		Penciclovir Sodium - This is your central hub for exploring the world of Penciclovir Sodium on the web.
	www.absoluteauthority.com /on/penciclovir-sodium.htm (294 words)

	Denavir Side Effects, and Drug Interactions - Penciclovir - RxList Monographs
		In two double-blind placebo-controlled trials, 1516 patients were treated with Denavir (penciclovir cream) and 1541 with placebo.
		Two studies, enrolling 108 healthy subjects were conducted to evaluate the dermal tolerance of 5% penciclovir cream (a 5-fold higher concentration than the commercial formulation) compared to vehicle using repeated occluded patch testing methodology.
		The 5% penciclovir cream induced mild erythema in approximately one-half of the subjects exposed an irritancy profile similar to the vehicle control in terms of severity and proportion of subjects with a response.
	www.rxlist.com /cgi/generic3/penciclovir_ad.htm (179 words)

	Penciclovir (Topical) - Gastonia, North Carolina
		Tell your doctor if you have ever had any unusual or allergic reaction to penciclovir.
		Topical penciclovir has not been studied in pregnant women.
		There is no specific information comparing the use of topical penciclovir in children with use in other age groups.
	www.caromont.org /17092.cfm (914 words)

	Herpes Simplex Virus Resistance to Acyclovir and Penciclovir after Two Decades of Antiviral Therapy -- Bacon et al. 16 ...
		Famciclovir and penciclovir are relative newcomers to the antiviral
		for penciclovir approximates to that for acyclovir ( 79).
		for susceptibility to penciclovir by the plaque reduction assay.
	cmr.asm.org /cgi/content/full/16/1/114 (8990 words)

	DrugsInfo.US - Online Penciclovir Information and Sales
		Penciclovir ( Denavir) is used on the lips and faces of adults to treat cold sores caused by herpes simplex virus.
		Follow the directions for using Penciclovir medicine provided by your doctor.
		If Penciclovir overdose is suspected, contact your local poison control center or emergency room immediately.
	www.drugsinfo.us /penciclovir.html (340 words)

	Buy Denavir / Penciclovir Online Cheap (Site not responding. Last check: 2007-11-04)
		Denavir / Penciclovir does not cure herpes infections but decreases pain and itching if applied when the earliest symptoms first appear.
		The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional.
		Although side effects from Denavir / Penciclovir are not common, they can occur.
	www.alfadrugs.com /denvir.html (309 words)

	Acyclovir And Penciclovir
		Find pictures and articles about acyclovir and penciclovir get support and help about acyclovir and penciclovir.
		You can find alternative treatments for acyclovir and penciclovir and books about acyclovir and penciclovir.
		Ganciclovir and penciclovir, but not acyclovir, induce apoptosis in...
	www.herpes-creams.com /2/herpes66.html (596 words)

	Pharmacokinetic Studies of 2-Amino-9-(3-acetoxymethyl-4-isopropoxycarbonyl-oxybut-1-yl)purine, an Oral Prodrug for the ...
		Pharmacokinetic Studies of 2-Amino-9-(3-acetoxymethyl-4-isopropoxycarbonyl-oxybut-1-yl)purine, an Oral Prodrug for the Antiviral Agent Penciclovir -- Choi et al.
		and AUC for penciclovir were 4.5 µM at 2.7 h and 28.2 µM
		The 0- to 24-h urinary recovery of penciclovir
	dmd.aspetjournals.org /cgi/content/abstract/29/7/945 (272 words)

	Famvir Prescriptions (Site not responding. Last check: 2007-11-04)
		It enters the body and turns into penciclovir, and it is the penciclovir that fights against the viruses.
		When you take FAMVIR, it is absorbed into your bloodstream, and then converted into another drug called penciclovir.
		Penciclovir stops the herpes simplex virus types 1 and 2 from multiplying, which may reduce the symptoms of the outbreak and helps sores to heal faster.
	www.famvir-prescriptions.org /product.html (139 words)

	Denavir buy denavir penciclovir (Site not responding. Last check: 2007-11-04)
		When you're trying to find superior info about buy denavir penciclovir, it'll be complex extricating superior advice from unprofessional buy denavir penciclovir suggestions and directions so it is clever to know how to moderate the advice you are presented with.
		Here's a few tips that we think you should use when you are searching for info about buy denavir penciclovir.
		All decent sites providing content on buy denavir penciclovir, will almost always provide an about or contact page which will record the owner details The details should divulge some indication about the owners expertise This lets you decide on about the webmasters education, to offer advice about buy denavir penciclovir.
	www.health-medication-now.com /denavir/buy-denavir-penciclovir.htm (153 words)

Try your search on: Qwika (all wikis)