
	Where results make sense

Topic: Pentobarbital

In the News (Sun 20 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Pentobarbital - Wikipedia, the free encyclopedia
		Pentobarbital is a short acting barbiturate that is available as both a free acid and a sodium salt, the former of which is only slightly soluble in water and ethanol.
		Pentobarbital undergoes first-pass metabolism in the liver and possibly the intestines.
		"Alterations in pentobarbital pharmacokinetics in response to parenteral and enteral alimentation in the rat".
	en.wikipedia.org /wiki/Pentobarbital (533 words)

	Guidelines for Pentobarbital
		Pentobarbital is one of the most common injectable general anesthetic agents used in rodents.
		Pentobarbital is one of the drugs belonging to the class of anesthetics known as barbiturates.
		Pentobarbital sodium occurs as white powder or crystalline granules that are freely soluble in water or alcohol to form a clear, colorless solution.
	vetmed.duhs.duke.edu /guidelines_for_pentobarbital.htm (426 words)

	Pentobarbital Sodium
		Pentobarbital is considered to be a drug of choice in dogs and cats for treating intractable seizures secondary to convulsant agents (e.g., strychnine) or as a result of CNS toxins (e.g., tetanus).
		Pentobarbital is metabolized in the liver principally by oxidation.
		Pentobarbital is a Class-II controlled substance and detailed records must be maintained with regard to its use and disbursement.
	www.elephantcare.org /Drugs/pentobar.htm (1161 words)

	pentobarbital - [Medication]
		Pentobarbital is used to treat insomnia (for up to 2 weeks) and to induce sleep before surgery.
		Pentobarbital is in the FDA pregnancy category D. This means that it is known to harm an unborn baby.
		Pentobarbital is available with a prescription generically and under the brand name Nembutal in capsules, suppositories, and as an injection.
	www.peacehealth.org /kbase/multum/d00335a1.htm (1338 words)

	Pentobarbital
		Pentobarbital is available as either the free acid or sodium salt.
		Pentobarbital is a popular short-acting barbiturate derivative used primarily as a sedative.
		The lethal dose level of pentobarbital is 2-10 g.
	www.sdrl.com /druglist/pentobarbital.html (320 words)

	MedlinePlus Drug Information: Pentobarbital Oral and Rectal
		Pentobarbital, a barbiturate, is used in the short-term treatment of insomnia (to help you fall asleep and stay asleep for a proper rest).
		Pentobarbital comes as a capsule and liquid to take by mouth and as a suppository to be used rectally.
		Pentobarbital can be habit-forming; do not take a larger dose, take it more often, or for a longer time than your doctor tells you to.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682416.html (751 words)

	What's In Your Dog's Food?
		Pentobarbital seems to be able to survive the rendering process.
		Dogs were given known quantities of pentobarbital for eight weeks to determine if consumption of small amounts of pentobarbital resulted in any physiological changes that could indicate potential effects on health.
		However, to get to the exposure level of 50 micrograms of pentobarbital per day, which is the highest level at which no biological response was seen, a dog would have to consume between 5 to 10 micrograms of pentobarbital per kilogram of body weight.
	www.flint-river-dog-food.com /pentobarbitol.htm (2091 words)

	Render Magazine
		The low levels of exposure to sodium pentobarbital (pentobarbital) that dogs might receive through food is unlikely to cause them any adverse health effects, Food and Drug Administration (FDA) scientists concluded after conducting a risk assessment.
		In order to determine if pentobarbital residues were present in animal feeds, CVM developed a sophisticated process to detect and quantify minute levels – down to two parts per billion of pentobarbital in dry dog food.
		Because pentobarbital is used to euthanize dogs and cats at animal shelters, finding pentobarbital in rendered feed ingredients could suggest that the pets were rendered and used in pet food.
	www.rendermagazine.com /April2002/ChowDownFido.html (1115 words)

	ASA: Oral Pentobarbital Superior to Oral Chloral Hydrate for Infant Sedation for Radiology Procedures (Site not responding. Last check: 2007-10-24)
		In the study, 985 children were sedated with oral pentobarbital and 331 with oral chloral hydrate.
		Oral pentobarbital failed to provide successful sedation in 0.005% of cases, while oral chloral hydrate failed to provide successful sedation in 2% to 8% of cases.
		Oral pentobarbital was also associated with significantly fewer episodes of oxygen desaturation (0.2% versus 1.6% for the two groups, respectively, P<0.01).
	www.pslgroup.com /dg/23ca6e.htm (547 words)

	Pentobarbital Oral - Drugs & Vitamins - Drug Library - DrugDigest
		Pentobarbital has sedative and hypnotic properties, which will help make you relaxed and sleepy when used before surgery.
		Federal law prohibits the transfer of pentobarbital to any person other than the patient for whom it was prescribed.
		In most cases pentobarbital should not be taken for longer than 1 or 2 weeks.
	www.drugdigest.org /DD/DVH/Uses/0,3915,529\|Pentobarbital+Oral,00.html (729 words)

	Pentobarbital Depressant Effects Are Independent of GABA Receptors in Auditory Thalamic Neurons -- Wan and Puil 88 (6): ...
		Pentobarbital has effects on the intrinsic membrane properties that depress the excitability of neurons.
		Pentobarbital application produced changes in membrane properties that corresponded to the observed decrease in firing.
		Pentobarbital produced mostly depressant and occasionally excitatory effects in thalamocortical neurons in vitro.
	jn.physiology.org /cgi/content/full/88/6/3067 (5606 words)

	Nembutal Side Effects, and Drug Interactions - Pentobarbital - RxList Monographs
		Pentobarbital sodium capsules are subject to control by the Federal Controlled Substances Act under DEA schedule II.
		Daily administration in excess of 400 milligrams (mg) of pentobarbital or secobarbital for approximately 90 days is likely to produce some degree of physical dependence.
		A dosage of from 600 to 800 mg taken for at least 35 days is sufficient to produce withdrawal seizures.
	www.rxlist.com /cgi/generic2/pentob_ad.htm (1145 words)

	Product Information on Pentobarbital Sodium 100MG
		The potency of the active ingredient(s), Pentobarbital Sodium.
		The date Pentobarbital Sodium was approved as stated in the FDA approval letter to the applicant.
		The group or category of approved drugs Pentobarbital Sodium is in.
	newdruginformation.com /Pentobarbital_Sodium.htm (155 words)

	Euthanasia Agents containing Pentobarbital
		For therapeutic uses (other than euthanasia) of pentobarbital, see the main pentobarbital monograph for this agent.
		The sections on chemistry, storage, pharmacokinetics, overdosage, drug interactions, and monitoring parameters can be found in the main pentobarbital monograph also.
		Pentobarbital alone is a Class-II controlled substance, combination products are generally Class-III.
	www.elephantcare.org /Drugs/euthanas.htm (496 words)

	Discriminative Stimulus Effects of Zolpidem in Pentobarbital-Trained Subjects: II. Comparison with Triazolam and ...
		Pentobarbital (25, 50, 100 and 150 mg) on average occasioned 50, 19, 85 and 94% pentobarbital-appropriate responding on the
		Ator, N. and Griffiths, R. Lorazepam and pentobarbital discrimination: Interactions with CGS 8216 and caffeine.
		Balster, R. and Moser, V. Pentobarbital discrimination in the mouse.
	jpet.aspetjournals.org /cgi/content/full/280/1/174 (7450 words)

	FDA/CVM Report on the risk from pentobarbital in dog food
		The investigation consisted of two parts. First, CVM had to determine if dog food could contain residues of the drug. Second, if residues were found, the Center had to determine what risk, if any, the residues posed to dogs.
		Pentobarbital seems to be able to survive the rendering process. If animals are euthanized with pentobarbital and subsequently
		Dogs that received 150 and 500 micrograms pentobarbital once daily for eight weeks had statistically higher liver weights (relative to their bodyweights) than the animals in the control groups. Increased liver weights are associated with the increased production by the liver of cytochrome P450 enzymes;
	www.wholepetvet.com /reports/Allman_DFreport.htm (492 words)

	Are Euthanized Pets In These Foods?
		For those who aren't aware, pentobarbital is the chemical of choice that vets and animal shelters use to put animals to sleep.
		The study by the FDA concluded that pentobarbital is indeed capable of surviving the rendering process and thus ending up in foods that contain euthanized pets.
		Their study says that the most likely way that pentobarbital can get in dog food is via rendered animals that were euthanized.
	www.petcaretips.net /euthanized_pets.html (882 words)

	Method for Determination of Pentobarbital in Dry Dog Food by Gas Chromatography/Mass Spectrometry (Site not responding. Last check: 2007-10-24)
		A procedure has been developed and validated for measuring the concentration of pentobarbital residues in dry, extruded animal feed in the range of 3-200 ng/g (ppb) with an estimated limit of quantitation of 2 ppb.
		Pentobarbital was eluted and derivatized for gas chromatography/mass spectrometry in positive ion chemical ionization mode.
		Accuracy ranged from 112% at 3 ppb to 96% at 200 ppb, with relative standard deviations ranging from 4% at 3 ppb to 2% at 200 ppb.
	pubs.acs.org /cgi-bin/abstract.cgi/jafcau/2001/49/i10/abs/jf0106188.html (229 words)

	Sodium Pentobarbital Permit
		The Sodium Pentobarbital Permit is mandatory for a humane society, county animal shelter or municipal animal shelter that buys, possesses and uses sodium pentobarbital for euthanasia of animals.
		A licensed veterinarian does not need this permit because issues related to sodium pentobarbital are also covered under the veterinarian license.
		An applicant must demonstrate an understanding and competence in the use of sodium pentobarbital.
	www.mda.state.md.us /licenses_permits/veterinary/sodium_pentobarbital_permit.php (252 words)

	Bicuculline and Gabazine Are Allosteric Inhibitors of Channel Opening of the GABAA Receptor -- Ueno et al. 17 (2): 625 ...
		The interactions of pentobarbital (B) are shown in Figure 8C.
		the case of pentobarbital it was assumed that the microscopic
		Nicoll RA, Wojtowicz JM (1980) The effects of pentobarbital and related compounds on frog motoneurons.
	www.jneurosci.org /cgi/content/full/17/2/625 (6583 words)

	Instructions for Sharing Sodium Pentobarbital
		However, some distributors of sodium pentobarbital may still be having trouble filling orders completely and some shelters are suffering.
		Instead, The HSUS is asking shelters that can spare some of the drug to share their supply with shelters in need.
		Please be sure to check with your state Board of Pharmacy to make sure the transfer of sodium pentobarbital is legal in your state.
	www.animalsheltering.org /resource_library/policies_and_guidelines/sodium_pentobarbital_sharing.html (494 words)

	Inhibition of Prostaglandin Synthesis and Effects of Ethanol and Pentobarbital in Humans -- Pickworth et al. 283 (1): ...
		Because the purpose of the present study was to examine the effects of indomethacin on either ethanol or pentobarbital, the
		The effects of pentobarbital on subjective measures were similar to those seen after ethanol (fig.
		effects of pentobarbital were seen on the motor control task.
	jpet.aspetjournals.org /cgi/content/full/283/1/274 (4361 words)

	Medical Dictionary: Pentobarbital - WrongDiagnosis.com
		Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally.
		It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration.
		Pentobarbital : short to intermediate acting barbiturate used as a sedative and hypnotic; the sodium salt is also used as an anticonvulsant, as a preanesthetic and as an adjunct to anesthesia.
	www.wrongdiagnosis.com /medical/pentobarbital.htm (239 words)

	Euthanasia
		When fully unconscious, 120 mg/kg of pentobarbital (2-3 ml / 4.5 kg of Euthanyl pentobarbital 240 mg/ml) is administered by intravenous or intracardiac injection.
		Inject 120 mg/kg of pentobarbital (2-3 ml/4.5 kg Euthanyl – pentobarbital 240 mg/ml) into the cephalic vein or saphenous vein.
		An injection in the marginal ear vein of 120 mg/kg of pentobarbital (20 mg/45 kg Euthanyl (240 mg/ml) or 10 ml/45 kg Euthanyl Forte – pentobarbital 540 mg/ml) is used.
	www.acc.ubc.ca /SOP/SOPeuthp.html (542 words)

	Effects of IV Pentobarbital With and Without Fentanyl on End-Tidal Carbon Dioxide Levels During Deep Sedation of ...
		Effects of IV Pentobarbital With and Without Fentanyl on End-Tidal Carbon Dioxide Levels During Deep Sedation of Pediatric Patients Undergoing MRI -- Connor et al.
		Sedatives used in pediatric imaging: comparison of IV pentobarbital with IV pentobarbital with midazolam added.
		The use of oral pentobarbital sodium (Nembutal) versus oral chloral hydrate in infants undergoing CT and MR imaging: a pilot study.
	www.ajronline.org /cgi/content/full/181/6/1691 (2390 words)

	Sedatives Used in Pediatric Imaging: Comparison of IV Pentobarbital with IV Pentobarbital with Midazolam Added -- Mason ...
		For MR imaging and CT studies in particular, motion artifacts should be at a minimum.
		incidence of paradoxical reactions to pentobarbital, and a 6.0%
		Intravenous sedation for MR imaging of the brain and spine in children: pentobarbital versus propofol.
	www.ajronline.org /cgi/content/full/177/2/427 (2945 words)

	Technical Services - Descriptions of Surgical Modifications (Site not responding. Last check: 2007-10-24)
		A sham intrathecal cannulation can be performed identically, with no insertion of the cannula taking place.
		Rats of bodyweight 50gms or greater are anesthetized with sodium pentobarbital (IP).
		A 2 cm craniocaudal skin incision is made parallel and slightly to the left of the sternum to expose the ribs.
	www.taconic.com /services/techdesc.htm (3697 words)

	Comparison of Intravenous Midazolam with Pentobarbital for Sedation for Head Computed Tomography Imaging -- ...
		Comparison of Intravenous Midazolam with Pentobarbital for Sedation for Head Computed Tomography Imaging -- Moro-Sutherland et al.
		In the pentobarbital group, 28 (97%) patients were scanned
		Intravenous pentobarbital is more effective than IV midazolam
	www.aemj.org /cgi/content/abstract/7/12/1370 (327 words)

	Pentobarbital-induced anesthesia : Epilepsy.com/Professionals
		For seizures during tapering: 50-mg pentobarbital bolus, then increase maintenance to closest preseizure dose
		Treatment of refractory generalized tonic-clonic status epilepticus with pentobarbital anesthesia after high-dose phenytoin.
		From Kolb SJ and Litt B. Management of epilepsy and comorbid disorders in the emergency room and intensive care unit.
	professionals.epilepsy.com /page/table_table_peno.html (248 words)

	Drug Information: Pentobarbital Oral and Rectal (Print Version)
		Drug Information: Pentobarbital Oral and Rectal (Print Version)
		To print this page, use the print option from your browser.
		To close this window, click on the "x" in the upper right hand corner of the window.
	www.nlm.nih.gov /medlineplus/print/druginfo/medmaster/a682416.html (740 words)

Try your search on: Qwika (all wikis)