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Topic: Pentothal


In the News (Tue 29 Dec 09)

  
  Belgium Palliative Care Workers Unable to Kill Patients Due to Shortage of Euthanasia Drug
Without the drug they say it is impossible to comfortably kill the on-average 30 patients a month who are officially euthanized in Belgium, as well as the speculated much larger number of patients whose deaths by euthanasia go unregistered as such.
The new producer of the drug, Hospira, however, has said that the shortage could soon come to an end, as they have a stockpile of 4,000 bottles of Pentothal which could be pumped into the market once the proper paperwork is filed.
Initially it was feared that it could be as long as three months before Belgium’s palliative care givers were able to kill their patients, but with Hospira’s emergency plan that time could be cut down to several weeks.
www.lifesite.net /ldn/2006/aug/06081103.html   (543 words)

  
  Data Sheet
PENTOTHAL is largely degraded in the liver and to a smaller extent in other tissues, especially the kidney and brain.
PENTOTHAL should be considered to have the same potential for producing respiratory depression as an inhalation agent, and patency of the airway must be protected at all times.
Thiopental sodium for injection is contraindicated in patients with severe respiratory embarrassment, hypersensitivity to barbiturates status asthmaticus, variegate or acute intermittent porphyria, and inflammatory conditions of the mouth, jaw, and neck and in the absence of suitable veins for intravenous administration.
www.medsafe.govt.nz /profs/Datasheet/p/Pentothalinj.htm   (2557 words)

  
 Truth drug - Wikipedia, the free encyclopedia
In episode 118 of MacGyver, a prisoner is given the choice of confessing freely or being injected with Sodium Pentothal.
In an episode of Batman: the Animated Series, Alfred Pennyworth is kidnapped and given a truth drug in an attempt to extract the combination to a missile silo.
In Lois McMaster Bujold's Vorkosigan Saga a drug called 'fast-penta' (which is obviously related to Sodium Pentothal in name if not in effects) is frequently used as a reliable means of interrogation, and testimony given under its influence is accepted in court by all governments mentioned, even testimony against oneself.
en.wikipedia.org /wiki/Truth_drug   (1475 words)

  
 H e a r t l a n d S c i e n c e - - The Ohio Academy of Science -
It was the world’s first such drug used regularly and became the model for development of a family of other “short-acting” barbiturate drugs that includes Brevital and Surital.
Sodium Pentothal is also used as a radioprotective drug, to help prevent tissue damage in patients undergoing radiation treatment for cancer and in individuals who encounter radiation for other reasons.
Sodium Pentothal got the name, Truth Serum, because patients under its influence – and guided by a skillful psychiatrist – lose some inhibitions and may talk freely about topics they might never otherwise discuss.
www.heartlandscience.org /medhs/anesthesia.htm   (658 words)

  
 What is Truth Serum?
Sodium Pentothal is a yellow crystal, which can be dissolved in water or alcohol.
Sodium Pentothal is commonly used as an anesthetic during surgery.
Sodium Pentothal is a radioprotective agent, which minimizes the effect of radiation.
www.psicologia.freeservers.com /diversos/soro_verdade.html   (642 words)

  
 Jim Garrison investigation: John F. Kennedy assassination: Clay Shaw preliminary hearing testimony
I think, to really convince that the test was a good one was the fact that after we discontinued the Pentothal and he was placed on oxygen to wake him up, after he was fully recovered from the effects of the drug, sodium Pentothal, he blurted out to Mr.
Because in the manner in which the conversations were carried on, the manner in which the conversations indicated certain activities, the manner in which dates that had to depend upon memory, also present happenings and also the coherence or the intelligence of the answer itself.
The effect of sodium Pentothal is that it removes any mental blocks that an individual may have, and it permits them to recall or regress and it can recount certain instances that they have relived, they have to experience these instances in able to recall them.
www.jfk-online.com /pre22chetta.html   (3349 words)

  
 [No title]
Pentothal induction was not associated with any marked change in the vital signs.
pentothal did not cause a drop in blood pressure to normal levels.
Pentothal has previously been reported to be a sympathetic ganglionic depressant.
history.amedd.army.mil /booksdocs/korea/Vol1-BattleCasualties/Chapter7.htm   (4984 words)

  
 Pentothal facts and comparsions at Drugs.com
Pentothal is usually administered as an injection at your doctor's office, hospital, or clinic.
Use Pentothal with caution in the ELDERLY because they may be more sensitive to its effects, especially drowsiness, depression, or confusion.
Pentothal is to be used only by the patient for whom it is prescribed.
www.drugs.com /cdi/Pentothal.html   (985 words)

  
 Newhouse B1
He said he did not consider use of sodium pentothal or similar drugs to be torture, but cautioned that information obtained should be used solely to disrupt or prevent terrorist attacks and never as evidence for prosecution in criminal trials.
Some experts doubt whether sodium pentothal would be an effective or reliable means of prying secrets from an obstinate prisoner.
He said the government should establish safeguards and controls for the use of sodium pentothal, taking into account the technical and moral issues involved, as well as international and domestic legal ramifications.
www.newhousenews.com /archive/story1b042602.html   (571 words)

  
 Aversion Therapy for Chemical Dependency
Narcotherapy (pentothal interview) is a component of the aversion therapy program designed to gather initial psychological diagnostic information and to monitor the development of aversion to the addictive substances.
Aversion therapy with pentothal interview is provided within a comprehensive treatment program that includes detoxification, counseling, addiction education, and introduction to a 12 step program for follow-up care.
Aversion therapy and pentothal interviews are considered investigational in the treatment of chemical dependency.
www.regence.com /trgmedpol/mentalHealth/mh16.html   (720 words)

  
 Erowid Psychoactive Vaults
It is not the only drug used, and the degree of usefullness lies with both the skill of the physician estimating dosage and the hypnotist.
---------------------------------------------------------------------------- >[Sodium pentothal stuff] > >I think there is some overlap with the old practice of using ethyl ether to >aid in obtaining psychodynamic 'catharsis,' which may or may not >relate to actual events in the patients personal history, >and overlap with some aspects of the use of hypnosis for similar purposes.
Sodium pentothal is the most commonly used induction agent for general anesthesia.
www.erowid.org /chemicals/other/sodium_pentothol_info1.shtml   (1821 words)

  
 10/17/2005 - State Supreme Court Upholds Tennessee’s Lethal Injection ‘Protocol’ - Breaking News - Chattanoogan.com
Levy testified that sodium Pentothal, Pavulon, and sodium chloride have well-known effects: sodium Pentothal is an ultra-fast acting barbiturate that is used in general anesthesia; Pavulon is a neuromuscular blocking agent that prevents nerve impulses from contracting muscles; and potassium chloride is normally used to increase a patient’s potassium level.
Dr. Levy testified, for instance, that the cause of Coe’s death was an “acute intoxication” by sodium Pentothal, Pavulon, and potassium chloride.
As a result, sodium Pentothal may only be dispensed by written prescription or by a practitioner directly to the user of the controlled substance.
www.chattanoogan.com /articles/article_74340.asp   (8268 words)

  
 OSCN Found Document:MARSHALL v. STATE
Currently, the law in Oklahoma regarding evidence of sodium pentothal or "truth serum" tests is that they are inadmissible for any purpose.
The reasoning usually given is that the tests have not demonstrated a [620 P.2d 445] sufficient degree of dependability to justify their use in the trial of criminal cases.
If a judge is ever to admit any testimony concerning the test or its results, he must be assured that the evidence is what it purports to be, otherwise it is clearly inadmissible.
www.oscn.net /applications/oscn/DeliverDocument.asp?citeID=5495   (1282 words)

  
 Manipulation under Anesthesia: Neurological Effects of Different Modes of Anesthesia | Brad McKechnie, DC, DACAN
Sodium Pentothal's liver clearance rate is from 15-20 percent per hour.
Should this procedure of sedation be utilized for a patient treated on an outpatient basis, it is necessary for someone to accompany the patient to the outpatient facility that will be able to drive the patient home after the procedure.
Versed has effects similar to those of sodium Pentothal with the exception that the memory loss for events occurring during the procedure is greater than with sodium Pentothal.
www.chiroweb.com /archives/10/08/02.html   (675 words)

  
 Lethal injection and the Georgia Supreme Court's new millennium
The members of the General Assembly left the details of Georgia’s lethal injection to the Department of Corrections.4 In developing lethal injection protocols, the department followed the lead of other states which have adopted lethal injection as a means of carrying out executions.
The most commonly used drugs for execution by lethal injection are sodium pentothal (as a sedative), pancurium bromide (stops respiration), and potassium chloride (stops the heart).
Pentothal is synonymous with Sodium Pentothal, Thiopental, and Sodium Thiopental.
www.criminaljustice.org /public.nsf/0/58d9387ad3f109af85256e5f0054e7ed?opendocument   (2009 words)

  
 NCADP: National Coalition to Abolish the Death Penalty
It was to have been monitored by two anesthesiologists to make sure Morales was unconscious from an initial dose of sodium pentothal before injection of paralyzing and heart-stopping drugs.
But the two physicians withdrew at the last minute, saying a court ruling had redefined their role to include possible active participation in the execution by adjusting the chemical doses if Morales showed signs of regaining consciousness.
Sodium pentothal is used as the first drug in the sequence.
www.democracyinaction.org /dia/organizations/ncadp/news.jsp?key=2270   (408 words)

  
 Anesthetic Agents of the Forties and Fifties
Ether, nitrous oxide, cyclopropane, and pentothal were used in 95% of general anesthetics in the 1940s and 1950s.
This manner of using pentothal was the reason for the many anesthesia-related deaths at Pearl Harbor.
However, the word got around that pentothal induction was pleasant and they all asked for "pentothal anesthesia" and told everyone that they had a "pentothal anesthetic" although they probably had only a few milliliters for induction only.
xnet.kp.org /permanentejournal/winter98pj/anesth.html   (1173 words)

  
 Barbiturate   (Site not responding. Last check: 2007-10-28)
The most important member of this class is sodium pentothal, which is used as an intravenous anesthetic from which recovery is rapid and which has the advantage of having very little or no side effects.
Barbiturates, particularly sodium pentothal, also have interesting applications in the field of psychology, since they can provide access to levels of consciousness not normally attainable except in dreams or trances.
This has earned sodium pentothal the nickname of a 'truth serum', even though in actuality it is neither a serum, nor does it guarantee the truth.
www.ch.ic.ac.uk /rzepa/mim/drugs/html/barbiturate_text.htm   (716 words)

  
 Today in Technology History - Apr 11
Pentothal is relatively safe and wears off very quickly.
However, Pentothal does not force a person to become honest, it merely reduces inhibitions -- so a person treated with Pentothal can still lie.
Pentothal can also help to prevent damage from radiation, which is perhaps why Dr. Tabern started studying the use of radioactive materials in medicine after 1946.
www.tecsoc.org /pubs/history/2002/apr11.htm   (325 words)

  
 Invent Now | Hall of Fame | Search | Inventor Profile
Ernest H. Volwiler and Donalee L. Tabern discovered the general anesthetic Pentothal, one of the most important agents in modern medicine.
Volwiler and Tabern discovered Pentothal in 1936 when they were seeking a substance which could be injected directly into the blood stream to produce unconsciousness.
Tabern, who held a number of patents, worked with Volwiler at Abbott and was associated with many of the company's scientific advances.
www.invent.org /hall_of_fame/142.html   (302 words)

  
 Pentothal (Thiopental Sodium) drug description - prescription drugs and medications at RxList
Pentothal (Thiopental Sodium for Injection, USP) is a thiobarbiturate, the sulfur analogue of sodium pentobarbital.
The drug is prepared as a sterile powder and after reconstitution with an appropriate diluent is administered by the intravenous route.
The following diluents in various container, syringe and vial sizes are provided in Pentothal Kits, Pentothal Ready-to-Mix Syringes and Vials for preparing solutions of Pentothal (Thiopental Sodium for Injection, USP) for clinical use:
www.rxlist.com /cgi/generic3/thiopental.htm   (326 words)

  
 Fine-Scale Organization of SI (Area 3b) in the Squirrel Monkey Revealed With Intrinsic Optical Imaging -- Chen et al. ...
Figure 4 illustrates two cases in which we examined submodality organization in area 3b using pentothal anesthesia.
Under pentothal (left), subtraction of pressure minus flutter (A), pressure minus vibration (B), and flutter minus vibration (C) reveal maps that are fairly gray without evidence of substructure within activation regions.
Under pentothal anesthesia, only the primary arbors are activated; each primary arbor projects divergently to the superficial layers (3 solid arrows).
jn.physiology.org /cgi/content/full/86/6/3011   (8817 words)

  
 [No title]
After a few minor questions such as: what was his name, where does he live, where does he work and did he know other individuals, I got into the main stream of questioning My first question pertained to his relationship with AL LANDRY.
My last question to RUSSO was something to this effect, "Is all that you are telling us true and to the best of your knowledge?" He said, "Yes, it is, as much as I can remember".
Chetta then informed us that he had been under sodium pento- thal for over a half-hour and the administration of sodium pentothal was concluded at 4:10 p.m.
mcadams.posc.mu.edu /russo3.txt   (1413 words)

  
 The pentothal test in the management of orthopaedic patients with hysterical illness -- Cornell et al. 89 (1): 37 -- ...
The pentothal test in the management of orthopaedic patients with hysterical illness -- Cornell et al.
The pentothal test in the management of orthopaedic patients with hysterical illness
patients evaluated under pentothal over the past two years are presented.
www.jrsm.org /cgi/content/abstract/89/1/37   (154 words)

  
 STATE POSTPONES MORALES EXECUTION / Judge's new order: Officials refuse to revise method of lethal injection
Tuesday, but it was postponed when two anesthesiologists withdrew their agreement to monitor the injection of a three-drug sequence and to make sure Morales was unconscious as he was being put to death.
Sodium pentothal is administered under that procedure to render a prisoner unconscious, and two other drugs paralyze his muscles and stop his heart.
Fogel's order Tuesday was unprecedented in two respects: It would have allowed execution with just sodium pentothal, something that has never been tried, and it would have required that the executioner be in the death chamber with Morales.
www.sfgate.com /cgi-bin/article.cgi?file=/c/a/2006/02/22/MNGSUHCJFB1.DTL   (1456 words)

  
 Induction
A steadily rising BP with this technique prior to the pentothal may mean that CO2 is rising.
Etomidate is often substituted for the initial dose of pentothal, especially in hypovolemic patients.
D. When inducing with a small amount of pentothal, if you find that you can't ventilate the patient, your options are: 1.
www.uam.es /departamentos/medicina/anesnet/gtoa/manualneuro/induction.html   (900 words)

  
 OSCN Found Document:STATE v. COOK
The defense offered his own testimony and testimony of the person who purportedly purchased the drugs from him to the effect that the defendant had not possessed any drugs that evening and that he had neither sold nor attempted to sell any controlled substances to the purported purchaser.
After both sides had presented their evidence, the court offered to withhold any final judgment in the case if the defendant would agree to take polygraph and sodium pentothal tests.
From this ruling, the State has perfected a timely appeal to this Court on a Reserved Question of Law pursuant to 22 O.S. [22-1053][3], asserting that the trial court should not have acquitted the defendant solely on the grounds of his willingness to take polygraph and sodium pentothal tests.
www.oscn.net /applications/oscn/deliverdocument.asp?citeid=1312   (968 words)

  
 (S-477)   (Site not responding. Last check: 2007-10-28)
Anesthesia was induced with propofol 2 mg/kg and an infusion of 0.12-0.18 mg/kg/min or with pentothal 4-5 mg/kg with additional 25-50 mg boluses as needed.
One patient receiving pentothal had onset times 20-30 sec longer than the group average.
All pentothal patients had some precipitate in the IV line.
www.iars.org /abstracts/abstracts/S386/s477.htm   (282 words)

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