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Topic: Peptide


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  Peptide - Wikipedia, the free encyclopedia
One convention is that those peptide chains that are short enough to be made synthetically from the constituent amino acids are called peptides rather than proteins.
Nonribosomal peptides and are confined primarily to unicellular organisms, plants, and fungi.
A peptide hormone is a peptide that acts as a hormone.
en.wikipedia.org /wiki/Peptide   (733 words)

  
 Peptide bond - Wikipedia, the free encyclopedia
Polypeptides and proteins are chains of amino acids held together by peptide bonds, as is the backbone of PNA.
The peptide bonds in proteins are metastable, meaning that in the presence of water they will break spontaneously, releasing about 10 kJ/mol of free energy, but this process is extremely slow.
The wavelength of absorbance for a peptide bond is 190-230nm.
en.wikipedia.org /wiki/Peptide_bond   (892 words)

  
 Peptide Synthesis
Peptides are synthesized by the solid-phase method using Fmoc chemistry on an Omega 396 multiple peptide synthesizer from Advanced ChemTech.
Peptides are slowly degraded particularly the cysteine-containing peptides are oxidized over time at -20°C. The water content of a given peptide powder varies depending on sequence of the peptide, storage conditions, handling, and other factors.
Maintain peptide in an oxygen-free environment as peptides having cysteine, methionine, trypophan, glutamine, and asparagine residues are susceptible to oxidation and have reduced self-life.
www.lerner.ccf.org /services/molecbiotech/peptide.php   (1164 words)

  
 Signal peptide: Facts and details from Encyclopedia Topic   (Site not responding. Last check: 2007-10-22)
Some signal peptides are cleaved from the protein by signal peptidase after the proteins are transported.
Signal peptides may also be called targeting signals or signal sequence[Follow this hyperlink for a summary of this subject]s.
The signal peptide that directs to the mitochondrial matrix has another sequence consisting of an alternate pattern which a few hydrophobic amino acids and a few plus-charged amino acids form.
www.absoluteastronomy.com /encyclopedia/s/si/signal_peptide.htm   (1026 words)

  
 Bachem peptide neuropeptide neuropeptides biochemicals peptides
Peptide and Biochemicals Peptide, Neuropeptide or Peptide, neuro peptide
Peptide or Biochemicals Peptide, Neuropeptide of Peptide, Biochemicals Neuropeptide of Peptide, Biochemicals peptide-YY peptide YY, peptide bond
Peptide or Biochemicals of neuropeptide and biochemicals peptide
www.bachem.com   (325 words)

  
 biology - Peptide
These peptides mimick the effects of morphine, and those who are unable to break them down will experience mental illness.
There is considerable movement to redefine this arbitrary distinction such that a peptide is an amino acid molecule without structure; on gaining defined structure it is a protein.
Thus the same molecule can be either a peptide or a protein depending on its environment; though there are often peptides which cannot be proteins.
www.biologydaily.com /biology/Peptide   (418 words)

  
 peptide
The number of amino-acid molecules present in a peptide is indicated by a prefix: a dipeptide contains two amino acids; an octapeptide, eight; an oligopeptide, a few; a polypeptide, many.
Solid-phase peptide synthesis consists of three distinct sets of operations: 1) chain assembly on a resin; 2) simultaneous or sequential cleavage and deprotection of the resin-bound, fully protected chain; and 3) purification and characterisation of the target peptide.
Peptides usualy purified by reversed-phase HPLC (high performance liquid chromatography) using columns such as C-18, C-8, and C-4.
www.biopeptide.com /peptide.htm   (425 words)

  
 Peptide Hormones
Its signal peptide is removed in the cisternae of the endoplasmic reticulum and it is packaged into secretory vesicles in the Golgi, folded to its native structure, and locked in this conformation by the formation of 2 disulfide bonds.
Additional peptides are derived from the preproprotein including glicentin which is composed of amino acids 1-69, oxyntomodulin is composed of amino acids 30-69 and the major proglucagon fragment (MPGF) comprises amino acids 72-158.
Glucose-dependent insulinotropic peptide (GIP) is derived from a 153-amino acid proprotein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide.
web.indstate.edu /thcme/mwking/peptide-hormones.html   (6426 words)

  
 Peptide Solutions   (Site not responding. Last check: 2007-10-22)
The total market for peptides therapeutics in 2004 was approximately US$15 billion, and is growing in excess of 15% pa. Although peptides are excellent drug leads and candidates, the instability of these molecules in the human body limits their therapeutic value and pharmaceutical use, thus providing the opportunity for Peptide Solutions Pty Ltd.
Peptide Solutions has developed a proprietary N-methylation technology platform (N-Scan) that enables it to manipulate and modify potential and existing peptide therapeutics towards increasing their effectiveness and duration of activity through increasing their stability.
Peptide Solutions focus is to re-engineer target peptides using its novel n-methyl amino acid portfolio together with other technologies which reduce the degradation and extend the life of peptides in the human body.
www.peptidesolutions.com   (236 words)

  
 Peptide Sequencing and Synthesis
When peptides and proteins larger than 20 to 40 amino acid units are to be sequenced, they are first broken into smaller fragments either by chemical or enzymatic partial hydrolysis.
When we are thinking of a peptide's sequence it is convenient to think of it as a chain which is stretched out, peptides are more commonly coiled (alpha helix, Brown p 518) or folded (beta sheet, Brown p 519).
In peptides it is commonly the N-H bonds of an amine and the oxygens of the carbonyl groups which participate in hydrogen bonds.
chemistry2.csudh.edu /rpendarvis/AmAcSeqSyn.html   (1592 words)

  
 Peptide Synthesis - Peptide Protein Research Ltd (PPR Ltd)
We are experienced in the synthesis of difficult and hydrophobic peptide sequences, and unusual peptide modifications.
Peptides are available in milligram to gram quantities, and a range of purities from crude peptides to >98%.
Peptides are routinely synthesised from 2 up to 60 amino acids in length, but depending on sequence longer peptides can be synthesised.
www.peptidesynthetics.co.uk   (130 words)

  
 THE PEPTIDE BOND   (Site not responding. Last check: 2007-10-22)
Tertiary structure is the arrangement of secondary structure elements in 3 dimensions and quaternary structure describes the arrangement of a protein's subunits.
As a consequence of this resonance all peptide bonds in protein structures are found to be almost planar, ie atoms Calpha(i), C(i), O(i), N(i+1) H(i+1) and Calpha(i+1) are approximately co-planar.
This rigidity of the peptide bond reduces the degrees of freedom of the polypeptide during folding.
www.cryst.bbk.ac.uk /PPS95/course/3_geometry/peptide2.html   (309 words)

  
 Peptide Synthesis
With peptide synthesis, it is a good idea to contact us before the synthesis is performed to discuss your peptide and the probablility of success in the synthesis.
After generation of the resin bound synthetic peptie, the stable blocknig groups are removed and the peptide is cleaved from the resin to produce a "free" peptide.
After the peptide is cleaved from teh resin, the resin is washed away and the peptide is extracted with ether to remove unwanted materials such as the scavengers usedin the cleavage reaction.
www.biotech.iastate.edu /facilities/protein/synthesis.html   (594 words)

  
 peptide hormones
The trivial names proposed for peptide hormones are given in the "Appendix." Abbreviations of the new names are not proposed, and the use of currently fashionable abbreviations is discouraged.
Since peptide hormones show species variation in their amino-acid sequence, their names are essentially "generic names", and are insufficient to specify a single chemical compound.
Thus, "thyroliberin" indicates the hypothalamic peptide stimulating the release (and perhaps also the biosynthesis) of thyrotropin, the corresponding tropic hormone, from the pituitary gland.
www.chem.qmul.ac.uk /iubmb/misc/phorm.html   (1062 words)

  
 Copper Peptide Serums - Anti-Aging Skin Care   (Site not responding. Last check: 2007-10-22)
Copper peptides, in combination with the use of exfoliating hydroxy acids, appear to be an excellent method for the reduction of scars and other skin lesions (keratoses, skin tags, some types of moles).
The only copper peptides that have been proven - by credible skin authorities who published their results in major dermatology journals - to improve skin and hair are those invented and patented by Dr. Pickart when he was at ProCyte Corporation and the newer breakdown-resistant, long-acting copper peptides that Pickart has since developed and patented.
Many single peptides (without copper) being advertised for skin renewal appear to be similar in action to scar producing peptides that were extensively studied for potential uses as wound healing drugs.
www.platinumskincare.com /blue-copper-peptide-cp-serum.htm   (2933 words)

  
 peptide
Brain natriuretic peptide in the management of heart failure *: the versatile neurohormone.
Using peptide maps as identity and purity tests for lot release testing of recombinant therapeutic proteins: FDA and biopharmaceutical industry stakeholders reach consensus on critical issues related to the use of peptide maps as identity tests for proteins and on their usefulness for lot release tests.
Pulmonary hemodynamic responses to brain natriuretic peptide and sildenafil in patients with pulmonary arterial hypertension *.
www.infoplease.com /ce6/sci/A0838245.html   (444 words)

  
 Copper Peptide: Perri Skin Care
This type of peptides have remarkable safety properties and are used in fluids used for intravenous feeding of hospital patients.
Such peptides are also used to make synthetic milk given to newborn infants when the babies have disease conditions that make them reject their mother's milk or milk from other animals such as cows and goats.
These breakdown-resistant, improved copper peptides give a longer-acting and stronger skin regeneration and also can be used with hydroxy acids and Retin-A. The single peptides (tripeptides or pentapeptides) used in many products are fragile, short-acting, and cannot be used with hydroxy acids.
www.homepeels.com /copper-peptide.html   (4507 words)

  
 Peptide Explorer is your source for Cathepsin, Immunomodulators, Caspase Inhibitors, and the Amino Acid Reference Chart.
Peptide Explorer is your source for Cathepsin, Immunomodulators, Caspase Inhibitors, and the Amino Acid Reference Chart.
Peptide Explorer offers the peptides you need, the information you want, in one location.
The Peptide Explorer offers a variety of product lines to chose from including cathepsin and granzyme inhibitors and substrates, immunomodulators, caspase inhibitors and substrates, neuropeptide y and peptide yy, and natriuretic peptides.
sigmaaldrich.com /Area_of_Interest/Biochemicals/Peptide_Explorer.html   (156 words)

  
 29th European Peptide Symposium, Gdansk, Poland, September 3-8, 2006
On behalf of the Polish Peptide Community and the Organizing Committee, we have the pleasure of inviting you to participate in the 29th European Peptide Symposium.
The thousand-year-old city of Gdansk is situated on the Bay of Gdansk and the southern coast of the Baltic Sea.
In the tradition of European Peptide Symposia, the 29th EPS will cover all aspects of the latest developments in peptide research, providing researchers with different backgrounds an opportunity to present and exchange ideas.
www.29eps.com   (259 words)

  
 amino acid - multiple sclerosis encyclopaedia
During transcription, a gene is echoed from the DNA into a complementary form called ribonucleic acid (RNA).
From the RNA, amino acids are produced and are joined with one another with a peptide bond.
The resulting sequence of amino acids is known as peptide string or polypeptide.
www.mult-sclerosis.org /aminoacid.html   (297 words)

  
 Peptide Music
The Awakening is produced by Peptide Music, and will be available on the DAWA label (with Suburban Music).
Peptide Music specialize in finding teachers and education services.
Peptide Music is part of the jackpisters.com webring.
www.peptidemusic.com   (217 words)

  
 BAM Biotech--Manufacturer of Peptide and Antibody
Peptide, amino acid and derivatives in large scale
We cooperated successfully with many pharmaceutical companies and developing biological research companies from more than 20 countries in the different development stages of a number of projects.
From the discovery of pre-choice medicine to the cGMP manufacture of the peptide, BAM is always your strategic partner.
www.bambio.com   (215 words)

  
 Peptide Resource Page: peptide reagents, peptide synthesis, custom peptides
Founded in 2004, the PRP is designed to help researchers and educators navigate through the maze of peptide related websites.
We also maintain an updated list of providers of peptide synthesizers and peptide sequencing services.
The Peptide Resource Page is your complete guide to peptide research and suppliers.
www.peptideresource.com   (100 words)

  
 CSBio Peptide Synthesizers and Custom Peptide Synthesis
This instrument is designed to perform an entire synthesis of any peptide of any length without being restricted by a limited number of amino acid additions.
C S Bio, People Who Know Peptides, has developed a complete line of fully automated peptide synthesizers.
Whether you need to synthesize peptides for research (0.2 to 5.0 grams resin), for industry (0.5 to 500 grams resin) or on a manufacturing scale (50 grams to 50 kilograms resin), C S Bio has a peptide synthesizer that will meet your needs.
www.csbio.com   (266 words)

  
 Global Peptide Services, LLC: Home
We couldn't be happier with the hundreds of peptides they have made for us in the past 4 years.
“Global Peptide Services has played a major role in support of our peptide drug targeting program at Tapestry Pharmaceuticals, Inc. We have relied on their expertise in both solid-phase synthesis and analytical support in the preclinical phase of new chemical entity (NCE) development.
“I have very impressed with the quality of the peptide that I ordered from Global Peptide Services, and I firmly believe that the high quality and purity have resulted in high quality data.
www.globalpeptide.com   (199 words)

  
 The Peptide Laboratory Home Page
resins; synthetic peptide analogues of the dopamine, muscarinic, and opioid receptors; peptide analogues of nNOS, iNOS, and eNOS, as well as numerous stock biologically active peptides.
Our technological improvements in the production of synthetic peptides and their use as analogues of biologically important proteins has thrust us to the forefront of synthetic peptide technology.
As the need for improved peptides, peptide analogues, and peptidomimetics continues to grow, be assured of our commitment to meet these needs.
www.peptidelab.com   (400 words)

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