| | Perfusion Magnetic Resonance Imaging to Assess Brain Tumor Responses to New Therapies (Site not responding. Last check: 2007-10-21) |
 | | Conclusions: Perfusion MRI not only may be as effective as radionuclide-based techniques in sensitivity and specificity in assessing brain tumor responses to new therapies, but also may offer higher resolution and convenient co-registration with conventional MRI, as well as time- and cost-effectiveness. |
 | | In rCBV perfusion imaging, the T2 (or T2*) MRI signal drop within or across a brain region is caused by spin dephasing from susceptibility effects during rapid passage of a paramagnetic contrast agent (eg, gadolinium) through the capillary bed. |
 | | Perfusion MRI techniques are likely to be at least as sensitive and specific as radionuclide-based techniques, and they offer the added advantages of higher intrinsic resolution, convenient co-registration with conventional MRI, and time- and cost-effective imaging in a patient population that already receives frequent follow-up conventional MRI studies. |
| www.moffitt.usf.edu /pubs/ccj/v5n2/article2.html (4893 words) |