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Topic: Peripheral blood smear

Related Topics

Complete blood count

Red blood cell distribution width

White blood cell

Spherocytosis

Neutrophil granulocyte

Chronic lymphocytic leukemia

Transferrin

Platelet

Light microscopy

Iron deficiency anemia

Hemoglobin

Iron deficiency (medicine)

Menstruation

Double elimination

Ferritin

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	Blood Smear: The Test
		The blood smear is primarily ordered to evaluate blood cell populations when a CBC with differential performed with an automated blood cell counter indicates the presence of abnormal or immature cells.
		Blood smear findings include the relative percentage of each type of WBC that is present.
		When a platelet count is suspiciously low, and/or the automated blood cell counter presents with a warning, the blood smear is used to determine whether or not there are adequate platelets present and to verify the presence of giant platelets, and/or platelet clumps.
	www.labtestsonline.org /understanding/analytes/blood_smear/test.html (1183 words)

	Blood smear
		Blood is drawn from a vein, usually on the inside of the elbow or the back of the hand.
		For an infant or young child, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet.
		The smear shows the relative number and kinds of white blood cells (differential), abnormalities in the shape of all types of blood cells, and a rough estimate of white cell and platelet counts.
	www.umm.edu /ency/article/003665.htm (544 words)

	Pathology Review Carousel 20 (Site not responding. Last check: 2007-10-10)
		Peripheral blood smear showing hypersegmented neutrophil in a patient with B12 deficiency.
		In megaloblastic anemia due to B12 or folate deficiency all of the hematopoietic cell lines (granulocytes, platelets, and red cells) may be affected and be decreased in the peripheral blood.
		Peripheral blood smear showing schizocytes and red blood cell fragments and decreased platelets in a patient with disseminated intravascular coagulation.
	medic.med.uth.tmc.edu /edprog/PATH/HemaI.HTM (263 words)

	Malaria Site: Malaria Simplified (Site not responding. Last check: 2007-10-10)
		eripheral smear examination for malarial parasite is the gold-standard in confirming the diagnosis of malaria.
		Thick and thin smears prepared from the peripheral blood are used for the purpose.
		Thin blood films stained by Giemsa’s or Leishman’s stain are useful for specification of parasites and for the stippling of infected red cells and have a sensitivity of 200 parasites/µl (0.004%).
	www.malariasite.com /malaria/staining_techniques.htm (1386 words)

	Teaching & Research Activities \| Teaching Resources \| Blood Smear
		Peripheral blood or potassium EDTA anticoagulated blood (1-2 mg EDTA/1 ml blood) may be used.
		Smears of peripheral blood must be made immediately.
		Place a 2-3mm drop of blood about 1cm from the frosted end of a clean slide that is on a flat surface.
	www.radil.missouri.edu /info/teaching/MakingBloodSmear.asp (327 words)

	New Page 1
		On admission, her temperature is 38.7 C (102 F), blood pressure is 140/90 mm Hg, pulse is 98/min, and respirations are 20/min.
		Examination of a peripheral smear from a patient with a hematocrit of 30% demonstrates large numbers of target cells.
		Autopsy examination of the main pulmonary arteries of a man presumed to have died from a massive cerebrovascular hemorrhage demonstrates a rubbery, congealed mass of blood that is easily detached from the vessel wall.
	iuhs-isa.org /PathHemeLymph.htm (6111 words)

	Bloodindex - Blood Specimen collection (Site not responding. Last check: 2007-10-10)
		Blood and bone marrow examinations constitute the major means of determining blood disorders like anemia, leukemia, porphyrias disorders, abnormal bleeding and clotting and inflammation, infection and inherited disorders of red blood cells, white blood cells, and platelets.
		Capillary blood is preferred for a peripheral blood smear and can also be used for other hematology studies.
		Before the bone marrow procedure is started, a peripheral blood smear should be obtained from the patient and a differential leukocyte count done.
	www.bloodindex.org /blood_specimen_collection.php (1138 words)

	Problems and labs, Blood
		One rat was exposed to hypoxia in a hyperbaric chamber.
		Blood cells may leave the bone marrow (where they develop) only after they have achieved a certain level of development.
		Eosinophils represent 1-3% of white blood cells in a peripheral blood smear.
	cellbio.utmb.edu /microanatomy/Blood.htm (852 words)

	Hemolytic Anemia - June 1, 2004 - American Family Physician
		Red blood cells with structural alterations of the membrane surface (including antibodies) are unable to traverse this network and are phagocytosed and destroyed by macrophages.
		Along with an assessment for pathognomonic red blood cell morphologies, such as spherocytes or schistocytes, examination of the white blood cells and platelets for coexisting hematologic or malignant disorders is essential.
		The diagnosis is based on the combination of spherocytosis noted on peripheral smear, a family history (in 75 percent of cases), and a negative DAT.
	www.aafp.org /afp/20040601/2599.html (3502 words)

	TS2Introduction to Microscopy and Peripheral Blood Smear, KOH & Wet Prep Workshop
		Note that a blood smear is first studied with an automated calculator programmed to recognize abnormal blood cell shapes and other irregularities. A more accurate smear is performed by a technologist. Low counts may be “hand counted” to ensure accuracy. The most accurate smear requires review by a pathologist.
		The differential WBC count, reticulocyte count, and examination of RBC morphology all require that a blood smear slide be prepared and properly stained.
		Blood can be collected from a fingerstick or heelstick and a drop can be placed directly on the slide. If drawn from venipuncture collect in a lavender tube to prevent clotting.
	faculty.washington.edu /alexbert/MEDEX/Winter/TS2MicroscopyBloodSmear.htm (1584 words)

	Leukemia Symptoms: Signs & Symptoms of Chronic Myeloid Leukemia \| Glivec.com
		The peripheral blood smear in a chronic phase CML patient often resembles a bone marrow aspiration.
		Accompanying the leukocytosis may be an increased platelet count (thrombocytosis) and an increase in the number of basophils (basophilia) and eosinophils (eosinophilia) in the peripheral blood, as well as in the bone marrow.
		Peripheral blood smear of a patient with chronic phase CML.
	www.glivec.com /content/target_cml/symptoms_cml.jsp (571 words)

	p990309a - Peripheral Smear
		Abstract: The CBC "with differential" presently includes a blood smear that is examined by the medical technologist and is available for the physician.
		With increased familiarity of the technique for blood smear preparation and interpretation, the emergency physician must include peripheral blood smear review as part of the emergency department evaluation of bleeding disorders, anemia, infectious disorders, and suspected leukemia.
		Knowing the variations in morphology of blood cells in specific disease states should help the physician to intelligently order and meaningfully interpret the peripheral blood smear.
	www.emory.edu /WHSCL/grady/amreport/litsrch98/p990309a.html (336 words)

	Full blood count (Complete blood count) - The Doctors Lounge(TM)
		Blood for a FBC is usually taken into an EDTA tube to stop it from clotting.
		Counting chambers, that hold a specified volume of diluted blood (as there are far too many cells if it is not diluted) are used to calculate the number of red and white cells per litre of blood.
		For example, a peripheral blood smear cannot prove presence of anemia per se, which must be detected by means of the hemoglobin, hematocrit, or RBC count.
	www.thedoctorslounge.net /hematology/labs/cbc.htm (902 words)

	Normocytic Anemia - November 15, 2000 - American Family Physician
		The red blood cell distribution width is a measure of the variability of the size (anisocytosis) of the cells and is usually reported as a component of automated CBCs.
		Because the diagnosis of normocytic anemia usually proceeds in a step-wise fashion that begins with the corrected reticulocyte index and examination of the peripheral blood smear, a patient-friendly, cost-effective and time-efficient strategy is to use a "draw and hold" order for possible later testing.
		The examination of the peripheral blood smear often yields diagnostic clues or confirmatory evidence.
	www.aafp.org /afp/20001115/2255.html (3076 words)

	Bloodindex - Information on Blood Tests and blood Types (Site not responding. Last check: 2007-10-10)
		The main function of the red blood cell (RBC or erythrocyte) is to carry oxygen from the lungs to the body tissues and to transfer carbon dioxide from the tissues to the lungs.
		The word hematocrit means “to separate blood,” which underscores the mechanism of the test because the plasma and blood cells are separated by centrifugation.
		Platelet activity is necessary for blood clotting, vascular integrity and vasoconstriction, and the adhesion and aggregation activity that occurs during the formation of platelet plugs that occlude (plug) breaks in small vessels.
	www.bloodindex.org /blood_types_info.php (6662 words)

	CDC: Relapsing Fever - Laboratory Testing
		The definitive diagnosis of TBRF is based on the observation of Borrelia spirochetes in smears of peripheral blood, bone marrow, or cerebrospinal fluid in a symptomatic person.
		Peripheral blood smear from (Schwan, Policastro et al.
		Incidental laboratory findings include normal to increased white blood cell count with a left shift towards immature cells, a mildly increased serum bilirubin level, mild to moderate thrombocytopenia (low platelet count), elevated ESR and slightly prolonged coagulation tests, PT and APTT.
	www.cdc.gov /ncidod/dvbid/RelapsingFever/RF_LabAnalysis.htm (309 words)

	2006 Hematopathology Specialty Conference Handout - Case 2
		Peripheral blood smear evaluation is a fundamental element in the evaluation of unexplained cytopenias.
		Flow cytometric immunophenotyping analysis performed on peripheral blood or bone marrow aspirate specimens is extremely useful in identifying and characterizing the abnormal cells of T-LGL and thereby establishing a diagnosis.
		When present in Wright-Giemsa stained peripheral blood smears the neoplastic HSTCL cells are cytologically malignant and usually have intermediate to large-sized, variably irregular nuclei and moderate amounts of basophilic cytoplasm which may or may not contain granules.
	www.uscap.org /site~/95th/spechemah2.htm (5818 words)

	Red Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions from MediaLab, Inc. (Site not responding. Last check: 2007-10-10)
		The blood study from which this smear was obtained revealed an MCV of 115(mm3).
		The peripheral blood picture shown in the photograph is most consistent with artifact of smear preparation.
		The PERIPHERAL BLOOD SMEAR is represented in the photograph.
	www.medialabinc.net /red-cell-disorders.asp (1195 words)

	Pathology
		Careful examination of the peripheral blood smear is of key importance to the diagnosis of leukemia.
		Peripheral smears of chronic leukemias usually show increased numbers of mature cells of a particular lineage (i.e.
		You should look for other peripheral blood smear abnormalities pertinent to a diagnosis of leukemia.
	www.med-ed.virginia.edu /courses/path/innes/wcd/leukmorph.cfm (707 words)

	Rouleaux formation -- 107 (11): 4205 -- Blood
		The stacking of cells (rouleaux formation) facilitates the rate of red cell sedimentation, a phenomenon that may be seen on a peripheral smear.
		The appearance of rouleaux may be artificially caused by a poor preparation of the smear or by viewing the slide in a thickened area.
		This patient also had plasma cells that were seen on the peripheral blood smear.
	www.bloodjournal.org /cgi/content/full/107/11/4205 (243 words)

	White Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions from MediaLab, Inc.
		The NEUTROPHIL on the PERIPHERAL BLOOD SMEAR in this photograph is a MAST CELL.
		A peripheral smear was submitted for morphology/clinical because of the number of MONOCYTES as captured in the upper and lower photographs.
		The peripheral smear photographed here was submitted for morphologic/clinical examination.The predominant cells comprised 70% of the total WHITE BLOOD CELLS and are consistent with LYMPHOCYTES in a 4 month old INFANT.
	www.medialabinc.net /white-cell-disorders.asp (1369 words)

	Red Blood Cells
		Erythrocytes in a peripheral blood smear derive their reddish colour from the protein haemoglobin, and usually appear round or oval with a pale-staining centre region.
		All red blood cells have a limited life span of around 100 to 120 days and must therefore be continuously replaced.
		Mature red blood cells are unable to synthesise new enzymes to replace those lost during normal cell metabolic processes due to their lack of inner organelles.
	www.fortunecity.com /greenfield/rattler/46/blood2.htm (675 words)

	Blood smear - Full Blood Count and Blood Smear - Patient UK
		A thin blood smear is stained with Wright-Giemsa stain to enable evaluation of white blood cell, red cell and platelet morphology.
		Blood smear from a P. falciparum culture (K1 strain).
		Slide 21: Blood Smear This medium to large lymphocyte is about twice as large as the RBC.
	roberts.onlineinfosource.com /?q=roberts-blood-smear (244 words)

	VITAMIN B12 DEFICIENCY ANEMIA
		Diagnostic of B12 defficiency are Macrocytic anemia, Macro-ovalocytes and hypersegmented neutrophils on peripheral blood smear.
		In severe cases the white blood cell count and platelet count are reduced, and pancytopenia is present.
		A red blood cell folate level of less than 150 ng/mL is diagnostic of folate deficiency.
	www.geocities.com /dreamerica/03b12.htm (881 words)

	RBC Tutorial (Site not responding. Last check: 2007-10-10)
		Correlate the results on a CBC laboratory report with the evaluation of a peripheral blood smear.
		A normal red blood cell is 2/3 the size of a small lymphocyte, or about the size of (or slightly smaller than)the lymphocyte nucleus.
		A peripheral blood smear (the slide is representative of this condition) shows red blood cells displaying macro- ovalocytosis and neutrophils with hypersegmentation.
	webpath.dmsf.edu.ph /LABS/RBCLAB/RBCLAB.HTM (541 words)

	Normal Peripheral Blood Smear (Site not responding. Last check: 2007-10-10)
		This slide is a normal peripheral blood smear stained with Wright's stain and viewed under 1000 X magnification.
		The majority of the cells seen are red blood cells.
		The white blood cell in the center is a segmented neutrophil.
	www.academic.marist.edu /~jzmz/HematologyI/Bloodsmears10.html (50 words)

	Pathology Review Carousel (Site not responding. Last check: 2007-10-10)
		Hairy Cell Leukemia, high power of peripheral blood smear showing a small normal lymphocyte and a "hairy cell" with finger nuclear chromatin, slightly larger nucleus and very lightstaining cytoplasm with fine cytoplasmic projections.
		Chronic Lymphocytic Leukemia, high power of peripheral blood smear showing numerous small lymphocytes which are morphologically normal, but represent a low-grade B cell malignancy.
		Chronic Myelogenous Leukemia, high power of peripheral blood smear showing numerous granulocytes of varying types and stages of development including both mature and immature cells.
	medic.med.uth.tmc.edu /edprog/PATH/HemaII.HTM (437 words)

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