| |
| | eMedicine - Hypertension : Article by Sat Sharma, MD, FRCPC, FACP, FCCP, DABSM (Site not responding. Last check: 2007-10-24) |
 | | The contribution of peripheral arterioles in maintaining blood pressure, described as "tone," was first described by Lower in 1669 and subsequently by Sénac in 1783. |
 | | Peripheral vascular resistance is dependent upon the sympathetic nervous system, humoral factors, and local autoregulation. |
 | | The vasoreactivity of the vascular bed, an important phenomenon mediating changes of hypertension, is influenced by the activity of vasoactive factors, reactivity of the smooth muscle cells, and structural changes in the vessel wall and vessel caliber, expressed by a lumen-to-wall ratio. |
| www.emedicine.com /MED/topic1106.htm (10263 words) |
|