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Topic: Pernicious anemia

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	Pernicious anemia - Wikipedia, the free encyclopedia
		Pernicious anemia refers to a type of autoimmune anemia.
		Pernicious anemia may cause inflammation of the tongue (glossitis).
		The treatment for pernicious anemia was first devised by William Murphy who bled dogs to make them anemic and then fed them various substances to see what (if anything) would make them healthy again.
	en.wikipedia.org /wiki/Pernicious_anemia (475 words)

	eMedicine - Pernicious Anemia : Article Excerpt by: Marcel E Conrad, MD
		Pernicious anemia occurs as a relatively common adult form of anemia that is associated with gastric atrophy and a loss of IF production and as a rare congenital autosomal recessive form in which IF production is lacking without gastric atrophy.
		Pernicious anemia probably is an autoimmune disorder with a genetic predisposition.
		Pernicious anemia is more common than is expected in families of patients with pernicious anemia, and the disease is associated with human leucocyte antigen (HLA) types A2, A3, and B7 and type A blood group.
	www.emedicine.com /med/byname/pernicious-anemia.htm (612 words)

	Pernicious Anemia: Vitamin B12 Deficiency
		Pernicious anemia is a type of anemia caused by a deficiency in vitamin B12.
		In pernicious anemia, the lack of vitamin B12 is due to the body's inability to produce enough intrinsic factor, a protein necessary for the absorption of vitamin B12.
		The primary form of treatment for pernicious anemia is a monthly vitamin B12 injection, but treatment depends on a multitude of factors, including the doctor's recommendation, the patient's personal preferences, the patient's overall health and the severity of the disease.
	www.gitract.info /intestinal-disorders/pernicious-anemia.php (718 words)

	MedlinePlus Medical Encyclopedia: Pernicious anemia
		Pernicious anemia is caused by a lack of intrinsic factor, a substance needed to absorb vitamin B-12 from the gastrointestinal tract.
		Pernicious anemia is a type of megaloblastic anemia.
		Pernicious anemia is seen in association with some autoimmune endocrine diseases such as type 1 diabetes, hypoparathyroidism, Addison's disease, hypopituitarism, testicular dysfunction, Graves disease, chronic thyroiditis, myasthenia gravis, secondary amenorrhea, and vitiligo.
	www.nlm.nih.gov /medlineplus/ency/article/000569.htm (943 words)

	Nikon MicroscopyU: Human Pathology Digital Image Gallery - Pernicious Anemia
		Anemia is a condition of the blood characterized by a deficiency of erythrocytes (also known as red blood cells), hemoglobin, or total volume.
		Pernicious anemia is a form of the disease that is associated with an inability of the body to absorb vitamin B12.
		If pernicious anemia is left untreated, irreparable neurological problems may develop that may become apparent as unsteadiness when walking, a tingling or a numb feeling in the hands and feet, irritability, memory loss, or severe personality changes that are sometimes referred to as megaloblastic madness.
	www.microscopyu.com /galleries/pathology/perniciousanemia.html (453 words)

	What is pernicious anemia?
		Pernicious anemia is a potentially fatal nutritional deficiency cause by the body's inability to absorb vitamin B-12, which is essential to the body's production of red blood cells.
		Pernicious anemia is caused by the absence of intrinsic factor, a substance secreted by the stomach.
		Like other anemias, pernicious anemia is associated with fatigue and a lack of energy, but in the absence of other characteristic symptoms, fatigue alone is unlikely to suggest a diagnosis of pernicious anemia.
	akak.essortment.com /whatispernicio_rtxl.htm (432 words)

	* Pernicious - (Disease): Definition
		Pernicious anemia (PA) was first described (although not by that name) in 1855 by the English physician Thomas Addison.
		Pernicious means wicked or mischievous, extremely hurtful, having quality of destroying or injuring, which certainly applied to this form of anaemia when it was first identified.
		Pernicious anemia (a type of blood problem)—Taking folic acid while you have pernicious anemia may cause serious side effects.
	en.mimi.hu /disease/pernicious.html (392 words)

	UAB Health System (Site not responding. Last check: 2007-09-20)
		The cause of pernicious anemia is not a lack of vitamin B-12 in the diet, but rather the inability of the digestive tract to absorb the vitamin from the intestine.
		Pernicious anemia was often fatal before doctors discovered the cause and developed an effective treatment.
		Pernicious anemia is not common and most often appears in people age 60 and older.
	www.health.uab.edu /show.asp?durki=61520&site=734&return=18687 (517 words)

	Pernicious Anemia - Anémie Pernicieuse - Anémie de Biermer
		Pernicious Anemia (PA) is an anemia which occurs in the terminal stages of the chronic destructive autoimmune disease, autoimmune gastritis.
		The term 'pernicious' described the inevitable progress and fatal outcome of the anemia and this given name by Biermer in 1972 has endured despite the knowledge that it is appropriate only to the terminal phase of the disease.
		Three pieces of evidence converge to suggest that there is a genetic predisposition to pernicious anemia: the high prevalence of pernicious anemia in some racial groups but not in others, the high frequency of pernicious anemia in families within those racial groups, and the association of particular genetic markers among patients with pernicious anemia.
	www.fortunecity.com /meltingpot/champion/627/AnemiePernicieuse.htm (2040 words)

	American RSDHope
		Pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B12.
		True pernicious anemia refers specifically to a disorder of atrophied parietal cells leading to absent intrinsic factor, resulting in an inability to absorb B12.
		Symptoms of pernicious anemia and decreased B12 affect three systems of the body: the system that is involved in the formation of blood cells (hematopoietic system); the gastrointestinal system; and the nervous system.
	www.rsdhope.org /Showpage.asp?PAGE_ID=33&PGCT_ID=2651 (780 words)

	Disease - Pernicious anemia - Detroit, Michigan
		This form of congenital pernicious anemia is inherited as an autosomal recessive disorder.
		Pernicious anemia is seen in association with some autoimmune endocrine diseases such as type 1 diabetes, hypoparathyroidism, Addison´s disease, hypopituitarism, testicular dysfunction, Graves disease, chronic thyroiditis, myasthenia gravis, secondary amenorrhea and vitiligo.
		People with pernicious anemia may have gastric polyps and have twice the incidence of gastric cancer and gastric carcinoid tumors than the normal population.
	www.henryfordhealth.org /15104.cfm (908 words)

	What Is Pernicious Anemia?
		Pernicious anemia (per-NISH-us uh-NEE-me-uh) is a condition in which the body does not make enough red blood cells due to a lack of vitamin B12 in the body.
		The condition was named “pernicious” anemia because it was often fatal in the years before the cause was discovered to be a lack of vitamin B12, and no specific treatments were available.
		Pernicious anemia is usually easy to treat with vitamin B12 pills or shots, although some people develop permanent nerve damage before they find out they have the disease and get treatment.
	www.nhlbi.nih.gov /health/dci/Diseases/prnanmia/prnanmia_what.html (699 words)

	Anemia, Pernicious
		Pernicious Anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12 (a cobalamin), which is essential for the development of red blood cells.
		Pernicious Anemia is a rare disorder that is thought to be an autoimmune disease.
		Pernicious Anemia of Adulthood may also be the result of the inability to absorb Vitamin B12 due to local intestinal inflammation (regional enteritis), surgery involving the small intestine, or the inability of the small intestine to absorb sufficient nutrients from food (malabsorption syndromes).
	hw.healthdialog.com /kbase/nord/nord79.htm (2293 words)

	Pernicious Anemia \| Caremark Health Resources
		Pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B
		Pernicious anemia seems to run in families, so that anyone with a relative diagnosed with the disease has a greater likelihood of developing it as well.
		Because an increased risk of stomach cancer has been noted in patients with pernicious anemia, careful monitoring is necessary, even when all the symptoms of the original disorder have improved.
	www.buildingbetterhealth.com /topic/pernicious (1259 words)

	Pernicious Anemia
		Pernicious anemia is therefore one of the types of megaloblastic anemia.
		There is a congenital form of pernicious anemia due to defect of intrinsic factor at birth that is clearly inherited as an autosomal recessive trait with the affected child having received two copies of the gene, one from each parent.
		Pernicious anemia was first described in 1855 by the English physician Thomas Addison.
	www.affordablerx.com /healthcare/Pernicious+Anemia (574 words)

	Pernicious Anemia
		Pernicious anemia is caused by an inability to absorb vitamin B12 (cobalamin) that is naturally found in certain foods.
		Megaloblastic anemia is due to a defect that develops in the formation of blood cells.
		This leads to anemia, meaning that there is a deficiency of normal red blood cells.
	www.animatedmedical.com /Pernanem/pernanem.html (637 words)

	Anemia, Pernicious
		Pernicious anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12, which is essential for the development of red blood cells.
		Pernicious anemia is thought to be an autoimmune disorder, and certain people may have a genetic predisposition to this disorder.
		There is a rare congenital form of pernicious anemia in which babies are born lacking the ability to produce effective intrinsic factor.
	www.webmd.com /hw/anemia/nord79.asp (531 words)

	Anemia, pernicious definition - Medical Dictionary definitions of popular medical terms
		Pernicious anemia is characterized by the presence in the blood of large, immature, nucleated cells (megaloblasts) that are forerunners of red blood cells.
		The name "pernicious anemia" was coined in 1872 by the German physician Anton Biermer whose description of the disease was superior to that of Addison.
		Murphy on the effects of feeding liver specifically in pernicious anemia (PA) led to the cure of PA and to their receiving the Nobel Prize in 1934.
	www.medterms.com /script/main/art.asp?articlekey=6855 (394 words)

	eMedicine - Pernicious Anemia : Article by Marcel E Conrad, MD
		Patients with pernicious anemia have a 2- to 3-fold increased incidence of gastric carcinoma.
		Anemia: The anemia often is well tolerated in pernicious anemia, and many patients are ambulatory with hematocrit levels in the mid teens.
		Outpatient follow-up of patients with pernicious anemia is required to ensure that they have responded to therapy with Cbl and that they continue to receive Cbl on a regular basis for the remainder of their life.
	www.emedicine.com /med/topic1799.htm (5739 words)

	Pernicious Anemia: An Explanation
		I have been diagnosed as having pernicious anemia and have been getting a B-12 shot once a month for the past year.
		Pernicious anemia (PA) results from inadequate vitamin B12, which is necessary for making healthy red blood cells.
		In classic pernicious anemia the person lacks "intrinsic factor," a substance made by the stomach which binds to the B12 in food and enables the B12 to be absorbed.
	healthlink.mcw.edu /article/901225865.html (230 words)

	Megaloblastic Anemia
		Megaloblastic (pernicious) anemia is a rare disorder in which the body does not absorb enough vitamin B12 from the digestive tract, resulting in an inadequate amount of red blood cells (RBCs) produced.
		Megaloblastic (pernicious) anemia results from a lack of intrinsic factor in gastric secretions (a substance needed to absorb vitamin B12 from the gastrointestinal tract).
		Megaloblastic (pernicious) anemia may also be associated with type 1 diabetes, thyroid disease, and a family history of the disease.
	www.umm.edu /blood/aneper.htm (353 words)

	Vitamin B-12 Deficiency
		Pernicious anemia is a form of anemia in which the body is not able to absorb enough vitamin B-12 from the digestive tract.
		Absence of intrinsic factor is the most common cause of pernicious anemia.
		Pernicious anemia is also seen in people who have had part, or all, of their stomach removed for cancer or other reasons, as well as in people with atrophic gastritis or those who take antacids.
	www.personalmd.com /news/vitaminb_05252000.shtml (694 words)

	Pernicious anemia, Eastern North Carolina, NC
		Pernicious anemia, Eastern North Carolina, NC To search for a specific phrase enclose that phrase in quotes.
		Pernicious anemia is a blood disease caused by the lack of a substance (intrinsic factor) that the body needs in order to absorb vitamin B
		In pernicious anemia, the body produces antibodies that either destroy the parietal cells (cells in the stomach that make intrinsic factor) or that block the action of intrinsic factor.
	www.uhseast.com /118344.cfm (256 words)

	Pernicious Anemia
		Pernicious anemia (PA) is the most common cause of vitamin B
		Anemia with symptoms that include fatigue, weakness, light-headedness, vertigo, tinnitus, palpitations, angina, CHF symptoms, decreased exercise capacity with pallor, slight icterus, tachycardia, and systolic flow murmur on exam.
		Megaloblastic anemias are characterized by ineffective erythropoiesis with enhanced intramedullary destruction of erythroblasts as evidenced an increase in indirect bilirubin and LD ·
	www.med.unc.edu /medicine/web/perniciousanemia.htm (1330 words)

	pernicious anemia - HighBeam Encyclopedia (Site not responding. Last check: 2007-09-20)
		PERNICIOUS ANEMIA; One man's journey through the baffling world of medical diagnosis
		Pulmonary embolism in a patient with pernicious anemia and hyperhomocysteinemia *.
		Pulmonary embolism in pernicious anemia and hyperhomocysteinemia.(communications to the editor)(Letter to the Editor)
	www.encyclopedia.com /html/X/X-pernicio.asp (168 words)

	Pernicious anemia - WrongDiagnosis.com
		Anemia due to poor intestinal absorption of vitamin B12 caused by defective production of intrinsic factor (a carrier protein) by the gastric mucosa.
		Detailed information about the causes of Pernicious anemia including medication causes and drug interaction causes can be found in our causes pages.
		With a diagnosis of Pernicious anemia, it is also important to consider whether there is an underlying condition causing Pernicious anemia.
	www.wrongdiagnosis.com /p/pernicious_anemia/intro.htm (479 words)

	How Is Pernicious Anemia Diagnosed?
		Pernicious anemia is diagnosed using a person’s medical history, physical exam, and tests that can determine the type and cause of anemia.
		Homocysteine is high in anemia due to the lack of vitamin B12 or folic acid.
		The level of methylmalonic acid is high in anemia due to a lack of vitamin B12 or folic acid.
	www.nhlbi.nih.gov /health/dci/Diseases/prnanmia/prnanmia_diagnosis.html (688 words)

	Pernicious Anemia Glossary of Terms with Definitions on MedicineNet.com
		The following are health and medical definitions of terms that appear in the Pernicious Anemia article.
		Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood.
		Pernicious anemia : A blood disorder caused by inadequate vitamin B12 in the blood.
	www.medicinenet.com /pernicious_anemia/glossary.htm (1217 words)

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