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Topic: Peyton Rous


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In the News (Fri 27 Nov 09)

  
  Francis Peyton Rous - Wikipedia, the free encyclopedia
Francis Peyton Rous (October 5, 1879, Texas - February 16, 1970, New York City) was an American pathologist whose discovery of cancer-inducing viruses earned him a share of the Nobel Prize for Physiology or Medicine in 1966.
Rous grew up in Baltimore and was educated at Johns Hopkins University and at the University of Michigan.
In 1910 Rous found that sarcomas in hens could be transmitted to fowl of the same inbred stock not only by grafting tumour cells but also by injecting a submicroscopic agent extractable from them; this discovery gave rise to the virus theory of cancer causation.
en.wikipedia.org /wiki/Peyton_Rous   (220 words)

  
 Nat' Academies Press, Biographical Memoirs V.48 (1976)   (Site not responding. Last check: 2007-10-18)
Peyton Rous discovered the viral etiology of a chicken sar- coma in 1911 through his interest in tumor tr~n~nl~nt~hilirv to 1, ~ - ~ YE new nosts oy a nitrate.
Moreover, Rous discovered a third chicken tumor, transmissible by filtrate, markedly different in properties from the two previously de- scribed: "The findings with the three tumor-producing agents have a striking similarity and it is difficult to avoid the con- clusion that the three are of one class, whatever that class may be....
Peyton Rous found no demonstrable antibodies in rabbits with- out papillomas or in those with tar papillomas or Brown-Pierce tumors: these findings "speak decisively against the possibility that these growths are caused by viruses antigenically related to the one causing papillomas.
www.nap.edu /books/0309023491/html/274.html   (4762 words)

  
 Peyton Rous Papers, American Philosophical Society
A pathologist, Francis Peyton Rous, was co-recipient of the Nobel Prize in Physiology and Medicine in 1966 for his discovery of carcinogenic viruses.
Rous returned from Europe to take up a grant from the Rockefeller Institute for Medical Research to pursue research on lymphocytes, during the course of which, he caught the eye of Simon Flexner, and earned a call to the staff at Rockefeller.
The papers of Peyton Rous are a large and diverse assemble of correspondence, manuscripts, and photographs relating to the medical researcher and Nobel laureate who developed the viral theory of the origins of cancer.
www.amphilsoc.org /library/mole/r/rous.htm   (1401 words)

  
 Peyton Rous - Biography
Peyton Rous was born in Texas in 1879.
In 1920 Peyton Rous became a Member of the Rockefeller Institute, and in 1945, when 65 years old, he became a Member Emeritus but continued to be busy in the laboratory as was the case until his death.
Peyton Rous married Marion Eckford deKay; she was the daughter of a scholarly commentator on the arts.
nobelprize.org /medicine/laureates/1966/rous-bio.html   (1061 words)

  
 Chapter Resources: All Chapters
In 1911, an American physician, Francis Peyton Rous, was studying chickens that had a tumor of the connective tissues called a sarcoma.
Rous decided to test the tumor for virus content, and he mashed up a section of tissue and passed it through a bacterial filter.
Rous did not refer to the infecting material as a virus, but others gradually did, and for many decades thereafter, the "Rous sarcoma virus" remained as a clear-cut example of a cancer-causing virus.
microbiology.jbpub.com /microfocus.cfm?chapter=11&MFNumber=3   (324 words)

  
 Francis Peyton Rous - Biocrawler definition:Francis Peyton Rous - Biocrawler   (Site not responding. Last check: 2007-10-18)
Francis Peyton Rous - Biocrawler definition:Francis Peyton Rous - Biocrawler
Francis Peyton Rous (October 5, 1879, Baltimore - February 16, 1970, New York City) was an American pathologist whose discovery of cancer-inducing viruses earned him a share of the Nobel Prize for Physiology or Medicine in 1966.
Rous was educated at Johns Hopkins University and at the University of Michigan.
www.biocrawler.com /biowiki/Peyton_Rous   (279 words)

  
 Cancer - Introduction to the Module
Nevertheless, the 30-year-old Peyton Rous was able to show that cell-free extracts from one chicken were able to cause the formation of the same type of tumor when injected into a second chicken.
Rous’ tumor extracts had been passed through a filter with pores so small that even bacteria were excluded.
Rous was later able to demonstrate that other types of chicken tumors could also be spread by their own, unique “filterable agents,” and that each would faithfully produce its original type of tumor (bone, cartilage, blood vessel) when injected into healthy animals.
science.education.nih.gov /supplements/nih1/cancer/guide/intro1.htm   (1549 words)

  
 Francis Peyton Rous Biography / Biography of Francis Peyton Rous Main Biography
Peyton Rous was born in Baltimore, Md., on Oct. 5, 1879.
Rous next attempted to show that a virus was present as a causative agent in mammalian tumors, but he failed, and it was not until the mid-1930s that he again turned to this line of research.
In the interim he developed methods of cultivating cancer viruses in test tubes and in chick embryos, did research in liver and gallbladder physiology, and was a principal figure in the development of blood banks.
www.bookrags.com /biography-francis-peyton-rous   (599 words)

  
 Active Skim View of: Francis Peyton Rous
Peyton Rous discovered the viral etiology of a chicken sarcoma in 1911 through his interest in tumor tr~n~nl~nt~hilirv to 1, ~ - ~ YE new nosts oy a nitrate.
These findings seem to have been for Rous the decisive argument for the validity of his conclusions concerning the chicken tumors, since in a mammal cancer could also be transmitted by a virus.
Peyton Rous found no demonstrable antibodies in rabbits without papillomas or in those with tar papillomas or Brown-Pierce tumors: these findings "speak decisively against the possibility that these growths are caused by viruses antigenically related to the one causing papillomas.
www.nap.edu /nap-cgi/skimit.cgi?isbn=0309023491&chap=274-307   (1020 words)

  
 The Rous Sarcoma Virus (RSV)
In 1911, Peyton Rous discovered that cancer could be induced in healthy chickens by injecting them with a cell-free extract of the tumor of a sick chicken.
In 1956, 55 years after his discovery of RSV, Peyton Rous was awarded a Nobel Prize in recognition of the key role that the virus has played in unlocking the secrets of cancer.
Rous was 87 at the time and fortunate to have lived to see his work honored.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/R/RSV.html   (1125 words)

  
 Peyton Rous: father of the tumor virus -- Van Epps 201 (3): 320 -- The Journal of Experimental Medicine   (Site not responding. Last check: 2007-10-18)
Peyton Rous: father of the tumor virus -- Van Epps 201 (3): 320 -- The Journal of Experimental Medicine
In 1910, Peyton Rous identified a transmissible avian tumor
Rous, however, did not report the first tumor virus.
www.jem.org /cgi/content/full/201/3/320   (590 words)

  
 HIV & AIDS - AIDS; The HIV Myth; Virus Hunters
As Renato Dulbecco writes in his memoir on Peyton Rous: ‘For about forty years this momentous discovery had little impact, because the minds of scientists were not prepared to think of viruses as agents of cancer.
Peyton Rous soon recognised himself that the tumour would not be accepted as a cancer because it was a cell-free extract,’ (i.e.
Peyton Rous’s chicken tumour was caused by one such retrovirus, the Rous sarcoma virus.
www.virusmyth.net /aids/data/javirus.htm   (14323 words)

  
 Francis Peyton Rous - TheBestLinks.com - February 16, October 5, University of Michigan, 1909, ...
Francis Peyton Rous - TheBestLinks.com - February 16, October 5, University of Michigan, 1909,...
Francis Peyton Rous, February 16, October 5, University of Michigan, 1909, 1910...
Although his research was derided at the time, subsequent experiments vindicated his thesis, and he received belated recognition in 1966 when he was awarded (with Charles B. Huggins) the Nobel Prize.
www.thebestlinks.com /Francis_Peyton_Rous.html   (249 words)

  
 Francis Peyton Rous, M.D., 1879-1970.
The collection includes a substantial series of files relating to Rous' involvement as editor of the Journal of Experimental Medicine, providing a glimpse into his editorial philosophy, and more generally, his philosophy on medical research.
Renato Dulbecco, "Francis Peyton Rous, October 5, 1879 - February 16, 1970," Biographical Memoirs of the National Academy of Sciences 48 (1976).
In particular Rous has not mentioned the pioneer research on blood transfusion with J. Turner and O. Robertson which led to the establishment in 1917 of the world's first blood bank near the front line in Belgium.
www.geocities.com /galenvagebn/RousFP.htm   (2089 words)

  
 ROUS, [Francis] Peyton [et al]., Observations on chicken tumors caused by filterable agents.   (Site not responding. Last check: 2007-10-18)
ROUS, [Francis] Peyton [et al]., Observations on chicken tumors caused by filterable agents.
Reprint of 15 papers by Peyton Rous, James B. Murphy, W.H. Tytler, Linda B. Lange, Oswald H. Robertson and Jean Oliver, published between 1910 and 1919 in the Journal of Experimental Medicine and the Journal of the American Medical Association.
Rous demonstrated that sarcomatous tumours in hens could be transmitted to normal hens by the injection of cell-free filtrates of the original tumour." The demonstration of the viral origin of the tumour was one of the most important discoveries in oncology.
www.polybiblio.com /phillips/1191.html   (280 words)

  
 AllRefer.com - Francis Peyton Rous (Medicine, Biography) - Encyclopedia
His long career included research in the physiology of the liver and blood (he helped develop blood banks).
The 1966 Nobel Prize in Physiology or Medicine was awarded jointly to C. Huggins and Rous.
More articles from AllRefer Reference on Francis Peyton Rous
reference.allrefer.com /encyclopedia/R/Rous-Fra.html   (220 words)

  
 Cancer Caused by an Infectious Agent
Rous, pronounced rows, Francis Peyton, pronounced PAY tuhn (1879-1970), an American medical researcher, proved that viruses cause some types of cancer.
In 1910, Rous ground up a cancerous tumor from a chicken and filtered out everything larger than a virus.
So in 1910, a maverick medical researcher proposed that cancer was caused by a virus and could be transmitted from chicken to chicken.
www.ellengwhite.info /cancer_germs_virus_rous.htm   (425 words)

  
 Levy Library - Mount Sinai School of Medicine
Only Dr. Peyton Rous, who had himself made such an announcement years before, spoke in her defense.
Peyton Rous was the speaker at the event.
Still, there was an unending struggle to find the funding to keep the lab well staffed and well equipped, a situation that got harder as federal funding began to shrink in the 1970s.
www.mssm.edu /library/services/archives/archives_collections/charlotte-bio.shtml   (714 words)

  
 USRF - Charles B. Huggins, M.D. (1901-1997)
Huggins was a pioneer in understanding the physiology and biochemistry of the male urogenital tract and was able to extend his findings from this field into many other areas.
In 1966, Dr. Huggins received the Nobel Prize (shared with virologist Peyton Rous) for his research on the relationship between hormones and prostate cancer.
Peyton Rous, who shared the prize with Dr. Huggins, was one of the first to recognize the true importance of Dr. Huggins' research.
www.usrf.org /news/010308-huggins.html   (1579 words)

  
 The Rockefeller University: News & Notes
In 1911 Peyton Rous discovered a tumor agent, later called the Rous Sarcoma Virus (RSV), that transmitted cancer in chickens.
Rous would later receive the Nobel Prize in Physiology or Medicine for this discovery.
In 1931, one of Rous’s colleagues, James Murphy, proposed that the tumor-inducing agent was a "transmissible mutagen," whose mode of activity was to induce permanent mutations in the host cells that resulted in cancer.
www.rockefeller.edu /pubinfo/news_notes/120800i.html   (341 words)

  
 Peyton Rous Biography / Biography of Peyton Rous World of Biology Biography
Francis Peyton Rous was born in 1879, in Baltimore, Maryland, to Charles Rous, a grain exporter, and Frances Wood, the daughter of a Texas judge.
A few months later, a poultry breeder brought a Plymouth Rock chicken with a large breast tumor to the Institute and Rous, after conducting numerous experiments, determined that the tumor was a spindle-cell sarcoma.
Each Biography is written by a biographical expert or professional educator and is a complete resource on the individual.
www.bookrags.com /biography-peyton-rous-wob   (259 words)

  
 Timeline of Microbiology 1910s–1920s   (Site not responding. Last check: 2007-10-18)
In 1909, a farmer brought Rous a hen that had a breast tumor.
Rous performed an autopsy, extracted tumor cells and injected them into other hens, which subsequently developed tumors.
Rous is awarded the Nobel Prize in Medicine or Physiology in 1966.
www.microbeworld.org /htm/aboutmicro/timeline/tmln_2.htm   (393 words)

  
 Rous Personal Info For Rous. This Person Is Currently Certified At Master Level Recent Diary Entrie   (Site not responding. Last check: 2007-10-18)
The story of Rous School is the history.
In 1911, Peyton Rous discovered that cancer could be induced in healthy chickens by injecting them with a cell-free The virus was named the Rous sarcoma virus (RSV.
Comstock, Elizabeth Leslie Rous Anglo-American Quaker minister and social reformer, an articulate abolitionist and an influential worker for social welfare who helped adjust the perspective of the Society of Friends to the changes wrought by the Elizabeth Leslie Rous Comstock.
www.99hosted.com /names15031.html   (339 words)

  
 The Hutchinson Encyclopedia: Rous, (Francis) Peyton (1879-1970)@ HighBeam Research   (Site not responding. Last check: 2007-10-18)
US pathologist who was awarded a Nobel Prize for Physiology or Medicine in 1966 for his discovery of tumour-inducing viruses (from his research on cancer in chickens).
Working at the Rockefeller Institute in New York, Rous first identified cancer-causing viruses.
In 1909, a poultry farmer took a chicken that had a tumour to Rous, who then prepared a cell-free filtrate from the tumour and injected it into...
www.highbeam.com /library/doc0.asp?DOCID=1P1:100172647&refid=ip_encyclopedia_hf   (186 words)

  
 The SH2 domain.
This was found in the Rous sarcoma virus and was shown to be the causative agent of chicken tumors.
It was discovered in 1911 by by Peyton Rous, and was early evidence that cancer could, at least sometimes, be caused by a virus.
In the 1970 and 80’s Michael Bishop and Harold Varmus cloned and sequence the Rous sarcoma genome and discovered one gene, which they called Src, was necessary and sufficient for transformation, i.e.
www.ufbi.ufl.edu /~shaw/sh2.htm   (727 words)

  
 AEGiS-UPI: Retroviruses are 'Unique in Biology'
LOS ANGELES - In 1910, at what is now New York's Rockefeller University, medical researcher Peyton Rous found out something special about chickens and a certain form of cancer.
When he inoculated unaffected members of his laboratory flock with the filtered residue of tumors from diseased chickens, cancers identical to the malignancies of the afflicted birds developed.
Rous later described the first link between cancer and a virus, but what he had found was the first retrovirus, one in a complicated group of microbes now linked to cancer and acquired immune deficiency syndrome.
www.aegis.com /news/upi/1986/UP861201.html   (1426 words)

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