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Topic: Phenmetrazine

	Phenmetrazine hydrochloride (PIM 942)
		Phenmetrazine hydrochloride International Programme on Chemical Safety Poison Information Monograph 942 Pharmaceutical
		Appetite suppressant (anorectic) for benzphetamine, diethypropion, phendimetrazine, phenmetrazine and phenteramine.
		Abuse either orally or by injection is extremely common.
	www.inchem.org /documents/pims/pharm/pim942.htm (4084 words)

	UNODC - Bulletin on Narcotics - 1968 Issue 2 - 003
		Phenmetrazine was the dominant drug among the stimulants, being used in 91 per cent of these cases, or in 74 per cent of all drug abusers (table 15).
		It was thought earlier that phenmetrazine had considerably weaker effects than the amphetamines; the light depressions and the psychopathic conditions that arose out of phenmetrazine abuse were said to be easily treated and it was denied in many quarters that tolerance, dependence and abstinence symptoms could emerge.
		phenmetrazine and methylphenidate, was only a fraction, about one million tablets a year, of the amount that must have been furnished by the illicit market.
	www.unodc.org /unodc/fr/bulletin/bulletin_1968-01-01_2_page004.html (10230 words)

	Phenmetrazine
		In trials in rats it has been found that after subcutaneous administration, both the optical isomers of phenmetrazine is equally effective in reducing food intake, but in oral administration the levo isomer is more effective.
		When stimulant abuse first became prevalent in Sweden in the 1950s, phenmetrazine was preferred to amphetamine and methamphetamine by addicts, as it was considered the superior drug.
		Phenmetrazine was classified as a narcotic in Sweden in 1959, and was taken completely off the market in 1965.
	www.danceage.com /biography/sdmc_Phenmetrazine (449 words)

	Gas chromatography-electron ionization and chemical ionization mass spectrometric analysis of urinary phenmetrazine ...
		The assay was linear for urinary phenmetrazine concentration of 1 to 100
		Phenmetrazine is a central nervous system stimulant currently used as an anorectic agent.
		Moreover, underivatized phenmetrazine showed poor peak shape (substantial tailing) while derivatized phenmetrazine had excellent chromatographic properties.
	www.astm.org /JOURNALS/FORENSIC/PAGES/2980.htm (371 words)

	Phenmetrazine (Preludin) and Methylphenidate (Ritalin)
		The medical indications, patterns of abuse, and adverse effects of phenmetrazine (Preludin) and methylphenidate (Ritalin) compare closely with those of the other stimulants.
		While the abuse of phenmetrazine involves both oral and intravenous use, most of that associated with methylphenidate results from injection after the drug in tablet form is dissolved in water.
		Complications arising from such use are common since the tablets contain insoluble materials that, upon injection, block small blood vessels and cause serious damage, especially in the lungs and retina of the eye.
	www.tpub.com /maa/76.htm (803 words)

	Phendimetrazine (phenmetrazine)
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	Dangerous Amphetamines
		Phenmetrazine and methylphenidate also amphetamine-like in that their medical indications, patterns of abuse and adverse effects closely resemble those of amphetamines.
		Phenmetrazine is medically used only as an appetite suppressant and methylphenidate mainly for treatment of hyperkinetic behavioural disorders in children.
		Complications arising from such use are common since the tablets contain insoluble materials, which upon injection, block small blood vessels and cause serious damage, especially in the lungs and retina of the eye.
	www.prn2.usm.my /mainsite/bulletin/sun/1996/sun26.html (1350 words)

	Phenmetrazine - Drug information from Medic8.com
		It was initially replaced by the weaker analogue Phendimetrazine (Bontril), but this is now only rarely prescribed, due to problems with abuse.
		It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.
		When stimulant abuse first became prevalent in Sweden in the 1950s, phenmetrazine was preferred to amphetamine and methamphetamine by addicts, as it was considered the superior drug.
	www.medic8.com /medicines/Phenmetrazine.html (0 words)

	Phendimetrazine - Phendimetrazine, Phendimetrazine Online, Phendimetrazine Vs Phenmetrazine
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	Phenmetrazine
		Phenmetrazine was originally sold under the tradename Preludin as an anorectic.
		Phenmetrazine is thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron leading to an increase in the release of these monoamines into the extraneuronal space.
		It is this latter effect on the tubero-infundibular systm that seems to lead to reduced food intake.
	www.mongabay.com /health/medications/Phenmetrazine.html (366 words)

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	eMedicine - Stimulants : Article by Krishna Divadeenam, MD
		Phenmetrazine is a stimulant that was widely prescribed for treatment of obesity in the United States in the 1950s and 1960s and in several European countries such as Sweden and Germany.
		A study of drug use among criminals found that for many methamphetamine addicts, phenmetrazine became their drug of choice.
		Abuse of this drug has ended because phenmetrazine was never illicitly manufactured and is no longer prescribed.
	www.emedicine.com /med/topic3094.htm (4290 words)

	Phenmetrazine
		The word "phenmetrazine" uses 13 letters: A E E E H I M N N P R T Z.
		Words within phenmetrazine not shown as it has more than seven letters.
		List all words starting with phenmetrazine, words containing phenmetrazine or words ending with phenmetrazine
	www.morewords.com /word/phenmetrazine (198 words)

	Phenmetrazine Hydrochloride, chemical structure, molecular formula, Reference Standards (Site not responding. Last check: )
		Phenmetrazine Hydrochloride, chemical structure, molecular formula, Reference Standards
		Assay— Transfer to a 200-mLvolumetric flask about 100mg of Phenmetrazine Hydrochloride,previously dried and accurately weighed.Dissolve in 0.5Nhydrochloric acid,dilute with 0.5Nhydrochloric acid to volume,and mix to obtain the Assay preparation.
		in which Cis the concentration,in µg per mL,of USP Phenmetrazine Hydrochloride RSin the Standard solution,and AUand ASare the absorbances from the Assay preparationand the Standard solution,respectively.
	www.ydzx.cn /pharmacopeia/usp28/v28230/usp28nf23s0_m63320.htm (129 words)

	Phenmetrazine Hydrochloride Tablets, chemical structure, molecular formula, Reference Standards (Site not responding. Last check: )
		Phenmetrazine Hydrochloride Tablets, chemical structure, molecular formula, Reference Standards
		»Phenmetrazine Hydrochloride Tablets contain not less than 93.0percent and not more than 107.0percent of the labeled amount of C11H15NO·HCl.
		Procedure— Determine the amount of C11H15NO·HCl dissolved from UVabsorbances at the wavelength of maximum absorbance at about 256nm on filtered portions of the solution under test,suitably diluted with Dissolution Medium,if necessary,in comparison with a Standard solution having a known concentration of USP Phenmetrazine Hydrochloride RSin the same Medium.
	www.ydzx.cn /pharmacopeia/usp28/v28230/usp28nf23s0_m63350.htm (126 words)

	FindLaw for Legal Professionals - Case Law, Federal and State Resources, Forms, and Code
		Second: That the defendant knew the unlawful purpose of the agreement and joined in it willfully, that is, with the intent to further the unlawful purpose;
		To distribute cocaine and phenmetrazine or preludes means for one person to intentionally transfer cocaine and phenmetrazine or preludes to another;
		And at the time of the transfer the person making the transfer knew that cocaine and phenmetrazine or preludes were controlled substances.
	caselaw.lp.findlaw.com /cgi-bin/getcase.pl?court=5th&navby=case&no=0030483cv0 (1917 words)

	Determination of Phenmetrazine in Urine by Gas ChromatographyMass Spectrometry (Site not responding. Last check: )
		A sensitive and simple gas chromatographic–mass spectrometric method is described for the determination of the central nervous system (CNS) stimulant phenmetrazine in urine.
		The extraction and derivatization were combined into a single step with isooctane and methyl chloroformate.
		Phenmetrazine was present in 83 out of 3000 urine samples that were screened for CNS stimulants during this period, and the concentrations ranged from 0.5–370 µg/mL.
	www.jatox.com /abstracts/1996/sept/277-kronstrand.htm (202 words)

	OSCN Found Document:HUMPHREY v. STATE
		Granville Lee Humphrey, appellant, was convicted of Possession of Phenmetrazine with Intent to Distribute, After Former Conviction of a Felony, in Oklahoma County District Court Case No. CRF-79-2639.
		He was sentenced to one year in the county jail and appeals.
		The brown bags were seized and found to contain seventy capsules of the drug, phenmetrazine, which were used as evidence against the appellant at trial.
	www.oscn.net /applications/oscn/DeliverDocument.asp?CiteID=5608 (643 words)

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	The Effect of Expectation on Response to Phenmetrazine -- PENICK and HINKLE 26 (4): 369 -- Psychosomatic Medicine
		The Effect of Expectation on Response to Phenmetrazine -- PENICK and HINKLE 26 (4): 369 -- Psychosomatic Medicine
		The Effect of Expectation on Response to Phenmetrazine
		LAWRENCE E. Division of Human Ecology, Departments of Medicine and Psychiatry, New York Hospital-Cornell Medical Center, New York, N. To investigate the effect of expectation on response to an appetite-depressing
	www.psychosomaticmedicine.org /cgi/content/abstract/26/4/369 (193 words)

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	Drug Information - Drugs of Abuse and Their Detection In Urine
		It should be noted that some of these drugs, such as phenmetrazine and phentermine, while not technically amphetamines, have similar abuse potential and similar adverse effects.
		If intoxication by any of the drugs listed below is suspected, it is recommended that the client contact the BandA pathologist, who will be glad to help determine a strategy as to how the case should be most efficiently handled.
		Some of them, such as phentermine, benzphetamine, fenfluramine and diethylpropion, may not be picked up on routine screens.
	www.cleartest.com /testinfo/illicit.html (2615 words)

	Phendimetrazine Tartrate-Generic 105mg. capsule from Eon Labs. (Site not responding. Last check: )
		The major route of elimination is via the kidneys where most of the drug and metabolites are excreted.
		Some of the drug is metabolized to Phenmetrazine and also Phendimetrazine-N-oxide.
		The average half-life of elimination when studied under controlled conditions is about 3.7 hours for both the extended-release and immediate release forms.
	www.anorectic-drugs.com /drugs/phendimetrazine/eonlabel.html (1265 words)

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	Determination of phenmetrazine in urine by gas chromatography-mass spectrometry after liquid-liquid extraction and ... (Site not responding. Last check: )
		Determination of phenmetrazine in urine by gas chromatography-mass spectrometry after liquid-liquid extraction and derivatization with perfluorooctanoyl chloride.
		Keywords: forensic science, forensic toxicology phenmetrazine, gas chromatography/mass spectrometry, gas chromatography-mass spectrometry, perfluorooctanoyl, perfluorooctanoyl derivative, phenmetrazine, toxicology
		Abstract: Phenmetrazine is a central nervous system stimulant and is currently used as an anorectic agent.
	journalsip.astm.org /jofs/PAGES/2654.htm (240 words)

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