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Topic: Phenylenediamine

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	m-, o- and p-PHENYLENEDIAMINE - (Organic Method #87)
		Phenylenediamines are particularly difficult to determine in air because they are very susceptible to oxidation reactions, which create sample stability and analytical problems.
		It became apparent that the free phenylenediamines are too unstable and the extracted samples must be kept acidic until analyzed.
		The major uses for phenylenediamines are in the manufacture of dyes.
	www.osha.gov /dts/sltc/methods/organic/org087/org087.html (3215 words)

	m-Phenylenediamine (CASRN 108-45-2), IRIS, Environmental Protection Agency
		Ninety-day toxicity study with m- phenylenediamine on rats.
		No effect was observed on body weight, food consumption, ophthalmology, hematology, or blood and urine biochemistry of treated rats.
		A significant increase in relative and absolute liver weight, accompanied by an increased incidence of degenerative liver lesions occurred in rats treated with 18.0 mg/kg/day m- phenylenediamine.
	www.epa.gov /iris/subst/0087.htm (772 words)

	Exposure Standard (Site not responding. Last check: 2007-10-15)
		Allergic reactions have been evoked in a human patient by a 1% solution of either o- or p- phenylenediamine
		The Working Group is of the view that this data, together with analogy with other phenylenediamine isomers, is sufficient evidence to support the sensitiser notation for this substance.
		After reviewing the relevant data, the Working Group is also of the view that the evidence for carcinogenicity is such that o-phenylenediamine might be suspected of having carcinogenic potential based on animal bioassay and genotoxicity data.
	www.nohsc.gov.au /OHSInformation/Databases/ExposureStandards/az/oPhenylenediamine.htm?BrowseMode=PrintPreview (539 words)

	hair colouring and cancer
		But, some of these compounds have been replaced by others of similar chemical structure, raising concerns that their cancer causing potential may not differ much from the original offending chemical ingredients.
		Leading brand name Wella simply states "Contains Ammonia, phenylenediamine".
		Koleston Perfect does contain ammonia and phenylenediamine and requires the use of hydrogen peroxide.
	www.slashhair.net /haircolour_cancer.html (531 words)

	Histogranin-Like Antinociceptive and Anti-Inflammatory Derivatives of o-Phenylenediamine and Benzimidazole -- Le et al. ...
		Bioactive histogranin-like derivatives of benzimidazole (1) and phenylenediamine (2–7) were made in four consecutive steps, first by the attachment of Boc-(L/D)Arg(Tos)-OH to MBHA resin using the PyBOP activation procedure (a) followed by the incorporation and reduction of nitroarene elements (b) and formylation /cyclization (c) or acylation of o-aminoaniline groups of resin-products (d).
		phenylenediamine (compound 2) was prepared in a similar manner
		phenylenediamine (compound 3) was prepared as described for
	jpet.aspetjournals.org /cgi/content/full/309/1/146 (6453 words)

	The Library
		Avoid choosing any product whatsoever listing the phenylenediamine chemical family.
		It is a key dye used in almost all permanent and semipermanent products.
		It should be further stressed that in 1986 para-phenylendiamine, the basic phenylenediamine dye in current use in virtually all permanent and semipermanent hair coloring products, was shown to be carcinogenic to the breast following oxidation with hydrogen peroxide.* However, this has never been further investigated.
	www.network54.com /Forum/message?forumid=246853&messageid=1050481306 (3705 words)

	Henna for Hair
		However, caveat emptor to anyone reading this with ulterior motives- I can guarantee you won’t make enough to cover your butt when you are sued.
		Many phenylenediamines are demonstrated to be mutagenic and carcinogenic per numerous studies.
		This use of PPD in prolonged skin contact application has the potential to induce allergic skin reactions in sensitive individuals.
	www.hennaforhair.com /ppd (5018 words)

	Hair color hair dyes Phenylenediamine, PPD, PPDA, p-phenylenediamine, para-phenylenediamine
		Hair color hair dyes Phenylenediamine, PPD, PPDA, p-phenylenediamine, para-phenylenediamine
		Farrell Hair Replacement - Voted #1 For 5 Consecutive Years!
		No part of this website can be reproduced.
	www.womenshair.info /articles/article6.htm (664 words)

	PPD Black Henna dangers
		Al-Tufail, M, Mahier, T., Tate, J., Haq, A., "Rapid Identification of Phenylenediamines in Traditional Hair Dyes by Gas Chromatography-Mass Spectrometry"
		Children who recieve PPD fl henna body art are apt to accidentally ingest the PPD!
		Averbukh, A, Modai D., Leonov Y, Weissgarten J., Lewisnohn G., Fucs, L, Golik A, and Rosenmann, E., Rhabdomyolysis and Acute Renal Failure Induced by Para Phenylenediamine
	reverndbunny.sphosting.com /mediappd.htm (2481 words)

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