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Toscana virus RNA in Sergentomyia minuta flies.(LETTERS)(Letter to the editor) - HighBeam Encyclopedia To the Editor: Toscana virus (TOSV) (family Bunyaviridae, genus Phlebovirus) is an arthropodborne virus transmitted by sandflies. Reports of infections in travelers, clinical research, and epidemiologic studies have shown that TOSV affects the central nervous system and is a major cause of meningitis and encephalitis in Mediterranean countries in which the virus circulates (1). Ecology of viruses isolated from sand flies in Italy and characterization of a new Phlebovirus (Arbia virus). www.encyclopedia.com /doc/1G1-149514733.html   (1216 words)

Phlebovirus on Find Articles To the Editor: Rift Valley fever (RVF) is caused by an RNA virus (Phlebovirus, Bunyaviridae), which is carried by mosquito vectors (1). Toscana virus (TOSV, Phlebovirus, family Bunyaviridae) infection is one of the most prevalent arboviruses in Spain. To the Editor: Sandfly fever Naples virus, Sandfly lever Sicilian virus, and Toscana virus (family Bunyaviridae, genus Phlebovirus) have been recognized... calbears.findarticles.com /p/search?tb=art&qt=Phlebovirus   (428 words)

[No title]   (Site not responding. Last check: 2007-10-17) The RVF virus belongs to the family bunyaviridae genus phlebovirus. The RVF virus is a RNA lipid-enveloped spherical structure, 80 nm to 120 nm in diameter and contain 5-nm to 10-nm surface spikes (G1 and G2). The virion spikes mediate the attachment of the virus to the host cell receptors, serve as hemagglutinin and are the targets for the host’s neutralising antibodies. www.pitt.edu /AFShome/S/u/Super1/public/html/lecture/lec4161/006.htm   (91 words)

ipedia.com: Rift Valley fever Article   (Site not responding. Last check: 2007-10-17) The disease is caused by the RVF virus, a member of the genus Phlebovirus. The disease is caused by the RVF virus, a member of the genus Phlebovirus (family Bunyaviridae). The disease was first reported among livestock in Kenya around 1915, but the virus was not isolated until 1931. www.ipedia.com /rift_valley_fever.html   (251 words)

Toscana virus in Spain.(RESEARCH) - HighBeam Encyclopedia Within the objectives of a multidisciplinary network, a study on the epidemiology of TOSV was conducted in Granada, in southern Spain. One of the objectives of the network is to study TOSV infections in Spain. TOSV (genus Phlebovirus, family Bunyaviridae) is an important agent of acute meningitis and meningoencephalitis in residents and visitors from Mediterranean countries (7-13). www.encyclopedia.com /doc/1G1-138659650.html   (3547 words)

MEDLINE Search on Medscape.com   (Site not responding. Last check: 2007-10-17) The S segment of Punta Toro virus (Bunyaviridae, Phlebovirus) is a major determinant of lethality in the Syrian hamster and codes for a type I interferon antagonist. Viruses in the Phlebovirus genus of the family Bunyaviridae cause clinical syndromes ranging from a short, self-limiting febrile illness to fatal... Apoptosis of hepatocytes caused by Punta Toro virus (Bunyaviridae: Phlebovirus) and its implication for Phlebovirus pathogenesis. search.medscape.com /medline-search?queryText=Phlebovirus   (437 words)

Toscana Virus in Europe | CDC EID Transient and low-level viremia is present after phlebovirus infection in humans and in susceptible laboratory animals (28–30). Ecology of viruses isolated from sand flies in Italy and characterized of a new Phlebovirus (Arbia virus). Viremia and immune response with sequential phlebovirus infections. www.cdc.gov /ncidod/EID/vol11no11/05-0869.htm   (4465 words)

Theoretical Biology and Medical Modelling | Full text | Proteomics computational analyses suggest that the carboxyl ... A model of phlebovirus Gc Recently, Gibbons and coworkers determined the structure of a fragment of the SFV E1 ectodomain (lacking carboxyl terminal aa 392–438) after exposure to low pH and liposomes [33]. As previously reported, phlebovirus Gc have a significant similarity to surface protein pvc2 encoded by plant viruses of the Tenuiviridae [40]. It is possible that the phlebovirus, orthobunyavirus and nairovirus M segment encoded nonstructural proteins, all with multimembrane-spanning potential, serve the same function for Gc. www.tbiomed.com /content/1/1/10   (7192 words)

Manual of standards for diagnostic tests and vaccines, 4th edition, 2000 It is caused by a single serotype of a mosquito-borne bunyavirus of the genus Phlebovirus. Rift Valley fever (RVF) is a peracute or acute, febrile, mosquito-borne, zoonotic disease caused by a virus of the family Bunyaviridae, genus Phlebovirus. It usually presents in epizootic form over large areas of a country and is characterised by high rates of abortion and neonatal mortality, and occurs primarily in sheep, goats and cattle. www.oie.int /fr/normes/mmanual/ancien_manuel/A_00029.htm   (5079 words)

Chapter 1 Genus: Bunyavirus (Bunyamwera subgroup) Genus: Phlebovirus (sandfly fever viruses) Genus: Nairovirus (Nairobi sheep disease-like viruses) Genus: Hantavirus (hemorrhagic fever with renal syndrome viruses) Characteristics: Genome consists of three molecules of minus-strand (ambisense for Phlebovirus) RNA held in circular configuration by hydrogen bonds. Replicate in cytoplasm and bud from the Golgi membranes. csm.jmu.edu /biology/courses/bio444_544/Chapter2.html   (1193 words)

CRORA : RESUME DES PUBLICATIONS Within the Phlebovirus serogroup, Rift Valley fever (RVF) virus is endemo-enzootic in the African sahelian zone. Because of the close antigenic relationship between the phleboviruses it appeared of interest to evaluate the prevalence of the other phleboviruses also. In 1987, 482 sheep serum samples were collected in 2 different ecological zones of Burkina Faso and tested for the presence of phlebovirus antibodies. www.pasteur.fr /recherche/banques/CRORA/res1/re354.htm   (223 words)

Phylogenetic relationships among members of the genus Phlebovirus (Bunyaviridae) based on partial M segment sequence ... Phylogenetic relationships among members of the genus Phlebovirus (Bunyaviridae) based on partial M segment sequence analyses -- Liu et al. Viruses in the genus Phlebovirus (Bunyaviridae) are of considerable Tesh, R. The genus Phlebovirus and its vectors. vir.sgmjournals.org /cgi/content/full/84/2/465   (3488 words)

News | Gainesville.com | The Gainesville Sun | Gainesville, Fla.   (Site not responding. Last check: 2007-10-17) Phlebovirus (Phleboviridae) is one of five genre of the family Bunyaviridae. Its members are class V virus with segmented ambisense RNA genomes. Proteomics computational analyses suggest that the carboxyl terminal glycoproteins of Bunyaviruses are class II viral fusion protein (beta-penetrenes) www.gainesville.com /apps/pbcs.dll/section?category=NEWS&template=wiki&text=Phleboviruses   (254 words)

CRORA : RESUME DES PUBLICATIONS   (Site not responding. Last check: 2007-10-17) Adult golden hamsters inoculated subcutaneously with either of two sandfly fever group viruses, Punta Toro and Gabek Forest (Phlebovirus, Bunyaviridae), developed a fulminating fatal illness characterized by hepatic and splenic necrosis and interstitial pneumonitis. Necropsy and histopathologic examination of the infected animals revealed pathologic changes involving multiple organs that resembled those described in Rift Valley fever. These two hamster-phlebovirus systems may serve as alternative animal models for Rift Valley fever and should be useful in studying the pathogenesis of severe phlebovirus infection and for testing potential therapeutic agents. www.pasteur.fr /recherche/banques/CRORA/res10/re5649.htm   (161 words)

[No title] One of the largest viral families with over 300 viruses, the Bunyaviruses have presented a significant challenge to taxonomists. The Phlebovirus genus comprises over 50 viruses which are transmitted by mosquitoes or phlebotomine flies. Rift Valley fever virus and sandfly fever virus are the most medically important agents which have been the greatest focus of study. www.stanford.edu /group/virus/bunya/classificationtaxonomy.html   (333 words)

PMID: 2728348   (Site not responding. Last check: 2007-10-17) Rift Valley fever virus M segment: phlebovirus expression strategy and protein glycosylation. Further analysis showed utilization of this glycosylation site, as well as proteolytic processing at the amino terminus of the mature glycoprotein G2, appeared to be determined by initiation codon usage. The two-site translational initiation expression strategy of this phlebovirus M segment and its role in the control of post-translational protein modification and processing are discussed. lethargy.swmed.edu /cgi-bin/etblast/abstract_local?pmid=2728348&user_id=107540030&application=0   (273 words)

Uukuniemi virus Terms and Definitions at www.MedicalGlossary.org Home > Organisms > Viruses > RNA Viruses > Bunyaviridae > Phlebovirus > Uukuniemi virus Terms and Definitions A species in the genus PHLEBOVIRUS of the family BUNYAVIRIDAE, infecting vertebrates and vectored by ticks. It has not been associated with human disease though antibodies have been isolated from human sera. www.medicalglossary.org /phlebovirus_uukuniemi_virus_definitions.html   (141 words)

European Society of Clinical Microbiology and Infectious Diseases Three pools were found to be positive with Phlebovirus generic primers whereas they were negative with TOSV specific primers. However another phlebovirus, Arbia virus, has been repeatedly isolated in Italy, though no sequence data is available. Arbia virus is currently being sequenced to determine the nature of the phlebovirus detected in these 3 pools. www.blackwellpublishing.com /eccmid16/abstract.asp?id=49025   (444 words)

CRORA : RESUME DES PUBLICATIONS   (Site not responding. Last check: 2007-10-17) The M RNA segment of Toscana (TOS) phlebovirus was cloned and the complete nucleotide sequence determined. The M RNA segment is 4215 nucleotides in length, and it contains a single major open reading frame (ORF) in the viral-complementary sequence, between nucleotides 18 and 4034, which can encode for a polyprotein of 1339 amino acids (Mr 149 kDa). Based on sequence comparison and similarity of hydropathic pattern of TOS M segment with other phleboviruses the N-termini of TOS G(N) and G(C) glycoproteins were placed at residues 297 and 936 of the precursor. www.pasteur.fr /recherche/banques/CRORA/res3/re1418.htm   (256 words)

The L protein of Rift Valley fever virus can rescue viral ribonucleoproteins and transcribe synthetic genome-like RNA ... The only animal Bunyaviridae member reported to bud at a site other than the Golgi is a strain of the phlebovirus Rift Valley Fever virus that was found to mature both intracellulary (in the Golgi) and at the plasma membrane in primary rat hepatocytes (Pettersson and Melin, 1996). Infection and release of Rift Valley Fever virus in polarized epithelial cells occurs at both apical and basolateral membranes and hence is bi-directional (Gerrard et al., 2002). The phlebovirus Rift Valley Fever is primarily hepatotropic (Schmaljohn, 1996). pathport.vbi.vt.edu /minet/xmlfiles/RVFV.xml   (9623 words)

WHO | 1998 - Rift Valley fever in Kenya Laboratory investigations, including on samples taken from animals, are continuing at NIV and another WHO Collaborating Centre, the Centers for Disease Control and Prevention (CDC) in Atlanta, USA. Rift Valley fever virus is a member of the family Bunyaviridae and is in the Phlebovirus genus. The virus was first isolated in 1931 during a disease outbreak in livestock on a farm located in the Rift Valley of Kenya. www.who.int /csr/don/1998_01_06b/en   (475 words)

Expression of S-segment   (Site not responding. Last check: 2007-10-17) Expression of the S-Segment of the Rift Valley Fever Genome The S-segment and its expression are highly characteristic of the genus phlebovirus. An ambisense coding strategy is used to translate the RVF nucleocapsid and nonstructural protein from the two non-overlapping open reading frames of the segment. justice.loyola.edu /~klc/BL472/RVF/rvf.sseg.html   (94 words)

PHLEBOVIRUS Specialty definitions using "PHLEBOVIRUS": Bunyaviridae ♦ Rift Valley Fever Virus ♦ Sandfly Fever Group Viruses ♦ Uukuniemi Group Viruses. Rift Valley Fever (RVF) virus is a member of the genus Phlebovirus in the family Bunyaviridae, first reported in livestock in Kenya around 1900. Source: pictures compiled by the editor from various references; see picture credits. www.websters-online-dictionary.org /definition/english/PH/PHLEBOVIRUS.html   (258 words)

Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, 5th edition, 2004 Rift Valley fever (RVF) is a peracute or acute zoonotic disease of domestic ruminants in Africa. The virus has a three-segmented, single-stranded, negative-sense RNA genome and consists of the three segments: L (large), M (medium) and S (small), each of which is contained in a separate nucleocapsid within the virion. It usually presents in epizootic form over large areas of a country following heavy rains and flooding, and is characterised by high rates of abortion and neonatal mortality, primarily in sheep, goats and cattle. www.oie.int /eng/normes/mmanual/A_00031.htm   (5738 words)

RVF   (Site not responding. Last check: 2007-10-17) Rift Valley Fever virus is a member of the Phlebovirus genera of the Bunyaviridae family. Members of the Phlebovirus genus (Rift Valley Fever and Sandfly Fever viruses) are so named because they can be transmitted by mosquitoes or phlebotomine flies. RVF virus was placed in this family because it has a tripartite genome and is antigenically similar to other phleboviruses. www.stanford.edu /group/virus/adeno/2000/RVF.html   (563 words)

Amazon.com: Phlebovirus   (Site not responding. Last check: 2007-10-17) virus) and animal viruses (the Phlebovirus genus of the bunyaviruses, and... Rift Valley fever Phlebovirus Coccidioidomycosis Coccidioides immitis Rubella Rubivirus... virus, a member of the phlebovirus genus, is associated with hemorrhagic... www.amazon.com /s?ie=UTF8&keywords=Phlebovirus&tag=tabularasa0f&index=blended&link_code=qs&page=1   (996 words)

Phlebovirus Terms and Definitions at www.MedicalGlossary.org Rift Valley fever virus - A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. Sandfly fever Naples virus - A species in the genus PHLEBOVIRUS causing PHLEBOTOMUS FEVER, an influenza-like illness. Uukuniemi virus - A species in the genus PHLEBOVIRUS of the family BUNYAVIRIDAE, infecting vertebrates and vectored by ticks. www.medicalglossary.org /bunyaviridae_phlebovirus_definitions.html   (259 words)

Evidence of Toscana Virus Variants Circulating in Tuscany, Italy, during the Summers of 1995 to 1997 -- Valassina et ... Toscana virus, genus Phlebovirus, is an enveloped virion with a segmented negative-strand RNA genome consisting of three noncovalently Organization of the M genomic segment of Toscana phlebovirus. Sequences and coding strategies of the S RNAs of Toscana virus and Rift Valley fever virus compared to those of Punta Toro, Sicilian sandfly fever and Uukuniemi viruses. jcm.asm.org /cgi/content/full/36/7/2103   (1359 words)

Bunyaviridae - Wikipedia, the free encyclopedia The L and M segment are negative sense. For the Genus of Phlebovirus, the S segment is ambisense. Ambisense means that some of the proteins on the RNA strand are negative sense. en.wikipedia.org /wiki/Bunyaviridae   (429 words)

Britannicaindia.com: Britannica Browse Hungarian boxer who became the first three-time Olympic boxing champion, winning gold medals in 1948, 1952, and 1956. acute, infectious, febrile disease caused by a phlebovirus (family Bunyaviridae) and producing temporary incapacitation. It is transmitted to humans by the bloodsucking female sand fly... www.britannicaindia.com /britannica_browse/p/p7.html   (1856 words)

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