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Journal of Drugs in Dermatology: Phosphatidylcholine in the treatment of localized fat Phosphatidylcholine was initially used in emergencies and in the treatment of atheroma plaques in cardiac diseases. Phosphatidylcholine is a phospholipid extracted from soybean lecithin present in abundance in cell membranes, actively participating in the structure and transport between the cells (1). Phosphatidylcholine seems to be efficacious and effective in these cases, representing a new, less invasive, and potentially promising treatment for conditions which include "buffalo-hump" (an unaesthetic condition related with HIV fat redistribution syndrome, or FRS), lipomas, eye bulging (12), and xanthelasmas. www.findarticles.com /p/articles/mi_m0PDG/is_5_2/ai_110220257   (1346 words)

Phosphatidylcholine Phosphatidylcholine, which is a polar lipid, is present in commercial lecithin in concentrations of 20 to 90%. Phosphatidylcholine is absorbed into the mucosal cells of the small intestine, mainly in the duodenum and upper jejunum, following some digestion by the pancreatic enzyme phospholipase, producing lysophosphatidylcholine (lysolecithin). Phosphatidylcholine is transported in the blood in various lipoprotein particles, including very-low-density lipoproteins (VLDL), low-density lipoproteins (LDL) and high-density lipoproteins (HDL); it is then distributed to the various tissues of the body. www.pdrhealth.com /drug_info/nmdrugprofiles/nutsupdrugs/pho_0288.shtml   (1577 words)

Choline Choline is a precursor for phosphatidylcholine, sphingomyelin, acetylcholine and the methyl donor betaine. Phosphatidylcholine's role in the maintenance of cell membrane integrity is vital to all of the basic biological processes: information flow, intracellular communication and bioenergetics. Choline deficiency-induced apoptosis in PC 12 cells is associated with diminished membrane phosphatidylcholine and sphingomyelin, accumulation of ceramide and ciccylglycerol, and activation of a caspace. www.pdrhealth.com /drug_info/nmdrugprofiles/nutsupdrugs/cho_0283.shtml   (1814 words)

Choline, Linus Pauling Institute's Micronutrient Information Center Choline is used in the synthesis of the phospholipids, phosphatidylcholine and sphingomyelin, structural components of all human cell membranes. The choline-containing phospholipids, phosphatidylcholine and sphingomyelin are precursors for the intracellular messenger molecules diacylglycerol and ceramide. Large doses of lecithin (phosphatidylcholine) have been used to treat patients with dementia associated with Alzheimer's disease in hope of raising the amount of acetylcholine available in the brain. lpi.oregonstate.edu /infocenter/othernuts/choline   (1900 words)

Phosphatidylcholine Phosphatidylcholine (derived from lecithin), a primary dietary source of choline, is composed of a phosphate group, 2 fatty acids, and choline. Phosphatidylcholine (PC) is the most abundant phospholipid of the cell membrane and protects the liver, with its 33,000 square meters of membrane, against toxicity and infection. Phosphatidylcholine (PC) is a phospholipid, one of a primal class of substances ubiquitous among life fonns. www.woodmed.com /Phos%20Choline.htm   (4019 words)

Lecithin   (Site not responding. Last check: 2007-10-13) Neither lecithin nor its ingredient phosphatidylcholine is an essential nutrient; however, choline has recently been recognized as essential. In Europe, phosphatidylcholine is also used to treat liver diseases, such as alcoholic fatty liver, alcoholic hepatitis, liver cirrhosis, and viral hepatitis. Finally, because phosphatidylcholine plays a role in nerve function, it has also been suggested as a treatment for various psychological and neurological disorders, such as Alzheimer's disease, bipolar disorder, Tourette's syndrome, and tardive dyskinesia (a late-developing side effect of drugs used for psychosis). www.al-hikmah.org /lecithin.asp   (580 words)

| Phosphatidyl Choline, Phosphatidylcholine, Lecithin, Weight Loss and Supplements | Wellfx.com Infobase | Choline is one of the few substances able to penetrate the blood-brain barrier, which ordinarily protects the brain against variations in the daily diet, and go directly into the brain cells to produce a chemical that aids memory. Phosphatidylcholine (a compound found in lecithin) and choline may both help ease the involuntary movements and spasms that are characteristic of Huntington's disease and Tourette's syndrome. Phosphatidylcholine supplements are a good way to get choline nutrition, and have been safely used in doses as high as 35 grams a day. www.wellfx.com /InfoBase/vitamin_choline.html   (558 words)

Liposomes In this context, phosphatidylcholine stands for living tissues whereas the increase of ceramides in the cells means that their death by apoptosis is soon ahead (Fig. Because phosphatidylcholine is known as a penetration enhancer, this property is usually associated with liposomes. One of the reasons to substitute phosphatidylcholine by polyglycerols and other synthetic derivatives at the beginning of the liposomal developments was its hydrolytic instability in aqueous preparations for longer periods of time and at higher temperatures. www.dermaviduals.de /publik/liposomes.htm   (2495 words)

i-Newswire.com - Press Release And News Distribution - Importation of European Phosphatidylcholine safer than FDA ...   (Site not responding. Last check: 2007-10-13) Soy-based lecithin in the form of injectable Phosphatidylcholine has become popular in the United States in use of Chelation therapy for coronary artery symptoms, and in a mixture of injections that promotes body sculpting without surgery with a procedure known as mesotherapy and lipodissolve. In Europe, quality phosphatidylcholine has been manufactured for more than 50 years with hundreds of research data behind it." The society is affiliated to research groups that provide information to physicians that offer cosmetic services in their clinics, by training them in face and body-sculpting procedures without surgery. Phosphatidylcholine has become popular in cosmetic use in procedures such as mesotherapy and lipodissolve and serve as one of the active ingredients. i-newswire.com /pr3209.html   (668 words)

Le Magazine, May 1998 - Report: Unique New Combination: Ginkgo And Phosphatidylcholine Phosphatidylcholine is the most active ingredient found in soy lecithin. Choline and lecithin phosphatidylcholine have been used with some success in treating Huntington's disease, tardive dyskinesia, Parkinson's disease, and other diseases of the nervous system. Most of the choline normally present in our diet is in the form of lecithin where it occurs in seed oils and in unrefined foods containing oil. www.lef.org /magazine/mag98/may98_ginphos.html   (2526 words)

Dr. Hal Brown - Naturopath Vancouver BC - Chelation Therapy Phosphatidylcholine Therapy is the New Non-surgical Swiss Treatment Protocol for Angina Pectoris Sufferers and arterial blockages. The Phosphatidylcholine treatment program involves, administering essential phospholipids in the form of Phosphatidylcholine parenterally (by intravenous infusion) to a patient to reverse age related changes in the lipid composition of organs and tissues, such as heart muscle cells, red blood cells and arteries by lipid exchange. Phosphatidylcholine is useful in the treatment of patients with angina pectoris, with reduced blood flow to the brain and extremities and prophylactically in the treatment against fat embolus and strokes. www.drhalbrown.com /chelation_therapy.php   (1617 words)

nutrition.org -- Nutritent Information   (Site not responding. Last check: 2007-10-13) Phosphatidylcholine, the predominant phospholipid (>50%) in most mammalian membranes, not only contributes to the structure of the membrane bilayer, but products of receptor-mediated lecithin hydrolysis also serve as important second messengers in signal cascades that control cell growth and gene expression. Disaturated phosphatidylcholine is the primary active component of surfactant in the lung; a deficiency of surfactant in the neonate leads to respiratory distress syndrome in premature infants. Plasma choline and phosphatidylcholine concentrations fall when humans are fed a choline-deficient diet or after strenuous, prolonged physical activity, such as running a marathon. www.nutrition.org /nutinfo/content/choline.shtml   (838 words)

Choline Supplementation for the Aging Brain and Other Therapeutic Applications Choline is an essential nutrient required to maintain cell membrane integrity and structure, as phosphatidylcholine is an important phospholipid, which helps contribute to the formation of the lipid bilayer within the cell membrane of each cell in the body. Phosphatidylcholine is an integral part of the structure and assembly system of the plasma lipoproteins (e.g., very low-density lipoproteins, which transport fat and cholesterol out of the liver) and of the microsomal membranes involved in the assembly and secretion process. Phosphatidylcholine supplementation also protects against alcohol-induced liver abnormalities and cirrhosis in baboons; presumably, it exerts the same effects in humans. www.chiroweb.com /columnist/meschino   (1244 words)

Control of phosphatidylcholine biosynthesis in myopathic hamster hearts.   (Site not responding. Last check: 2007-10-13) Upon perfusion with [Me-3H]choline, a 22% increase in labeling of phosphatidylcholine was observed in the hearts of 150-200-day-old myopathic hamsters. In order to elucidate the cause for the increase in labeling of phosphatidylcholine during cardiomyopathy, the intermediates for phosphatidylcholine formation in the myopathic hearts were analyzed. Furthermore, the net amount of phosphatidylcholine synthesized was estimated to be similar between the normal and myopathic hearts. www.arclab.org /medlineupdates/abstract_7107638.html   (244 words)

Phosphatidylcholine   (Site not responding. Last check: 2007-10-13) Phosphatidylcholine (PC) is one of the most important support nutrients for the liver. Phosphatidylcholine (PC) is a phospholipid nutrient that is a major building block for all known cells. Phosphatidylcholine is a highly bioavailable form of choline; it is also the most biologically significant and (for damaged livers, at least) the safest source of choline. www.thorne.com /altmedrev/fulltext/phos1-4.html   (7764 words)

Science In Your Eyes - Billedgalleriet The lipid POPC (palmitoyl-oleoyl phosphatidylcholine) is spread over a surface of mica by the use of a special spin-coating technique. A liposome composed of POPC (palmitoyl-oleoyl phosphatidylcholine), with the addition of the peptide makulatin, an active antibiotic from the skin of an Australian frog. Cluster of lipid membranes composed of DLPC (dilaureoyl phosphatidylcholine) and DPPC (dipalmitoyl phosphatidylcholine). scienceinyoureyes.memphys.sdu.dk /galleri_en.php   (1158 words)

Phosphatidylcholine : by Ray Sahelian, MD, phosphatidylcholine research phosphatidylcholine benefits Lecithin is known as phosphatidylcholine, although lecithin is also a term loosely applied to describe a combination of phosphatidylcholine with other phospholipids. Phosphatidylcholine is the most abundant phospholipid component in all cells. Phosphatidylcholine levels in brain cell membranes decline with age, perhaps contributing to memory loss. www.raysahelian.com /phospha.html   (1534 words)

Look Great Every Day...LIPODISSOLVE & MESOTHERAPY Phosphatidylcholine injections are not a substitute to diet and expercise or fat loss solution for highly obese persons. Phosphatidylcholine causes a good bit of edema (swelling), and is fairly irritating resulting in redness, itching and warmth. Phosphatidylcholine (PPC) or Lipostabil is an antioxidant that is derived from natural soy lecithin. www.myfatdissolve.com /faq.html   (9485 words)

LIPOPLASTY (LIPOSUCTION) WITHOUT SURGERY: MIRACLE, MAGIC, OR SCAM?   (Site not responding. Last check: 2007-10-13) The only published study using phosphatidylcholine for this purpose treated only 30 patients (on their lower lids), with a maximum follow-up of two years. The injection of phosphatidylcholine into subcutaneous tissues can potentially trigger the release of enzymes (lipases), which break down lipids or act as an emulsifier or detergent to dissolve cell membranes and intracellular fats. As the leading provider of Continuing Medical Education in cosmetic plastic surgery to board-certified plastic surgeons, ASAPS encourages open-mindedness in regard to any new modalities, but the public must be cautious in regarding such treatments as "harmless" without scientific evidence of their safety and efficacy. surgerynews.net /news/1203/fat12301.htm   (756 words)

Doctor Recommendations   (Site not responding. Last check: 2007-10-13) A key component of the nutrient lecithin, phosphatidylcholine is now available in purified supplement form for treating a variety of liver, nerve, and other conditions. In addition, phosphatidylcholine is a lipotropic agent that removes excess fat from the liver, a condition that can develop as a result of choline deficiency. That's because of the phosphatidylcholine in the lecithin. www.wholehealthmd.com /hc/doctortips/0,2316,489_10040,00.html   (643 words)

Alternative Medicine Review: Phosphatidylcholine - Monograph   (Site not responding. Last check: 2007-10-13) Controlled study using multiply-unsaturated phosphatidylcholine in comparison with placebo in the case of alcoholic liver steatosis. Activity of polyunsaturated phosphatidylcholine in HBsAg negative (autoimmune) chronic active hepatitis and in acute alcoholic hepatitis. Polyunsaturated phosphatidylcholine and interferon alpha for treatment of chronic hepatitis B and C: a multicenter, double-blind, placebo-controlled trial. www.findarticles.com /p/articles/mi_m0FDN/is_2_7/ai_85522987/pg_2   (846 words)

lecithin and choline   (Site not responding. Last check: 2007-10-13) Many nutritionally oriented doctors consider phosphatidylcholine a valuable nerve-building nutrient that might be able to help slow or reverse memory loss. Phosphatidylcholine is believed to speed the flow of fats and cholesterol through the liver, prevent the buildup of fats within the liver, and assist the liver in eliminating dangerous toxins from the body. Because individual phosphatidylcholine, lecithin, or choline supplements can increase levels of acetylcholine, they should not be used by individuals who are suffering from bipolar disorder. www.wholehealthmd.com /refshelf/substances_view/1,1525,10040,00.html   (857 words)

Regulation of apolipoprotein secretion by biliary lipids in newborn swine intestinal epithelial cells -- Wang et al. ... of taurocholate and phosphatidylcholine on apo A-I synthesis, H]glycerol (12 µCi/well) and taurocholate (2.0 mM) and/or phosphatidylcholine In adult rat studies, it was shown that cholesterol absorption was negatively correlated with jejunal apo B synthesis (10). ajpgi.physiology.org /cgi/content/full/276/2/G353   (5326 words)

Mesotherapy Treatments fOR Facial Rejuvenation   (Site not responding. Last check: 2007-10-13) Sodium Deoxycholate has always been present in formulas for phosphatidylcholine and until recently it was thought that it was the phosphatidylcholine that destroyed the fat cell. Conclusion: The injection of phosphatidylcholine (250 mg/5ml) into the fat pads is a simple office procedure that may postpone or even substitute for lower eyelid blepharaplasty. Phosphatidylcholine is a bile component and is responsible for the lipids' emulsification from the diet. www.aestheticmd.com /face.shtml   (1109 words)

phosphatidylcholine - Find, Compare, and Buy at Shopping.com Phosphatidylcholine (lecithin) is an excellent source of choline, a B vitamin. Promotes Brain Metabolism Citicoline [stabilized CDP Choline (cytidine 5' diphosphocholine)] is a naturally occurring, water soluble biological compound that is an essential intermediate for the synthesis of phosphatidylcholine, a major constituent...... Phosphatidylcholine (lecithin) is an excellent source of choline, a B vitamin, PC is a main component of cell membranes and is critical for brain and...... www.shopping.com /xGS-phosphatidylcholine   (918 words)

Phosphatidylcholine 60 cap | Discount Health Supplements from DrugNatural.com  Phosphatidylcholine, or PC, is a polar lipid molecule that is anaturally occurring, integral component of the cellularmembrane, adding fluidity and strength to cells. Pure Encapsulations Phosphatidylcholine is derived fromsoy lecithin, a source that is rich in polyunsaturated fattyacids, as opposed to animal-derived sources, which tendto be much higher in saturated fatty acids. phosphatidylcholine 420 mg.(from 1,200 mg of soy lecithin concentrate). www.drugnatural.com /p/680963   (505 words)

Phosphatidylcholine participates in the interaction between macrophages and lymphocytes -- Nishiyama-Naruke and Curi ... Phosphatidylcholine participates in the interaction between macrophages and lymphocytes -- Nishiyama-Naruke and Curi 278 (3): 554 -- AJP - Cell Physiology The role of phosphatidylcholine molecules as mediator for the control of lymphocyte proliferation by macrophages was investigated. Arachidonic acid-rich phosphatidylcholine (AA-PC) and arachidonic acid-poor phosphatidylcholine (FA-PC) were added to the cell culture at the beginning of the proliferation experiments. ajpcell.physiology.org /cgi/content/full/278/3/C554   (3403 words)

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