| | Drug Tolerance Responds To Learned Cues |
 | | Drug tolerance makes people need more and more drug to get the same effect, whether pain relief or a "high." Its newly discovered psychological aspect -- in which a drug-predictive cue primes the body to react "as if" the drug effect is imminent -- might be used to treat addiction more effectively. |
 | | In short, if drug tolerance can be learned, there is a chance it can be unlearned, reducing or eliminating the tolerance-related cravings and other withdrawal symptoms that can lead addicts to relapse. |
 | | This probe dose usually is too small to have any effect, but, in rats that had prior experience with larger infusions of morphine, it replicated the drug onset cue - - a cue that previously had occurred shortly before the drug's peak effect. |
| www.apa.org /releases/drug_tolerance.html (1107 words) |