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Topic: Phytohaemagglutinin

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	Phytohaemagglutinin - WrongDiagnosis.com
		Name of the Organism: Phytohaemagglutinin (Kidney Bean Lectin) This compound, a lectin or hemagglutinin, has been used by immunologists for years to trigger DNA synthesis in T lymphocytes, and more recently, to activate latent human immunodeficiency virus type 1 (HIV-1, AIDS virus) from human peripheral lymphocytes.
		Besides inducing mitosis, lectins are known for their ability to agglutinate many mammalian red blood cell types, alter cell membrane transport systems, alter cell permeability to proteins, and generally interfere with cellular metabolism.
		Associated Foods: Phytohaemagglutinin, the presumed toxic agent, is found in many species of beans, but it is in highest concentration in red kidney beans (Phaseolus vulgaris).
	www.wrongdiagnosis.com /fda_bad_bug_book/phytohaemagglutinin.htm (930 words)

	Histol Histopathol, Vol 13, Pryme et al (Site not responding. Last check: 2007-10-23)
		The growth of a transplantable murine non-Hodgkin lymphoma tumour, developing either intra-peritoneally as an ascites tumour or subcutaneously as a solid tumour, has been shown to be markedly diminished by including phytohaemagglutinin (PHA), a lectin present in raw kidney bean (Phaseolus vulgaris) in the diet.
		In NMRI mice fed PHA within the range 0.45-7.0 mg/g diet, tumours which developed during a 10 day period after subcutaneous injection of cells were about 35% of the dry weight of those in lactalbumin-fed (control) animals.
		Experiments with a second murine tumour cell line (a plasmacytoma) in Balb/c mice gave similar results indicating that the effect of PHA was not restricted to a single tumour system.
	www.hh.um.es /Abstracts/Vol_13/13_2/13_2_24.htm (308 words)

	Phytohaemagglutinin
		Structure and or Composition of Toxin: Phytohaemagglutinin, a kidney bean lectin, is the presumed toxic agent and is found in many species of beans.
		Phytohaemagglutinins are composed of subunits with different binding sites.
		Thus, the preventive measure of red kidney bean poisoning is to eat well cooked kidney beans.
	chemweb.calpoly.edu /chem/bailey/377/PapersW01/Mui/structure.html (152 words)

	Reversible effect of phytohaemagglutinin on the growth and metabolism of rat gastrointestinal tract -- Bardocz et al. ...
		Reversible effect of phytohaemagglutinin on the growth and metabolism of rat gastrointestinal tract -- Bardocz et al.
		Reversible effect of phytohaemagglutinin on the growth and metabolism of rat gastrointestinal tract
		Phytohaemagglutinin in the diet influences the size, metabolism, and
	gut.bmjjournals.com /cgi/content/abstract/37/3/353 (389 words)

	[In vitro synergic lymphocyte stimulation in HIV-1 infected patients using inosine derivatives and radio-detoxified ...
		Therefore, stimulation of peripheral lymphocytes of human immunodeficiency virus-1 infected patients in successive clinical stages was studied by phytohaemagglutinin and other stimulants.
		Stimulation by phytohaemagglutinin decreased in patients with AIDS related complex to 63.1%, with AIDS to 13.6% of control values.
		Radio-detoxified endotoxin alone or in combination with phytohaemagglutinin stimulated lymphocytes of both controls and patients with AIDS related complex slightly.
	www.aegis.com /aidsline/1995/jul/M9570571.html (509 words)

	US FDA/CFSAN - Bad Bug Book - Phytohaemagglutinin
		This compound, a lectin or hemagglutinin, has been used by immunologists for years to trigger DNA synthesis in T
		Diagnosis is made on the basis of symptoms, food history, and the exclusion of other rapid onset food poisoning agents (e.g., Bacillus cereus, Staphylococcus aureus, arsenic, mercury, lead, and cyanide).
		The AGRICOLA button will provide a list of research abstracts contained in the National Agricultural Library database for this organism or toxin.
	vm.cfsan.fda.gov /~mow/chap43.html (931 words)

	Mechanism of Lymphocyte Transformation induced by Phytohaemagglutinin
		The role of phytohaemagglutinin (PHA) determinants and lymphocyte surface reactive sites has been investigated in the lymphocyte transformation phenomenon.
		Results suggest that the mitogenic moiety of the PHA molecule is closely related to or identical with the antigenic determinant sites, and that some of these PHA antigenic sites are similar to those found amongst the antigenic configuration on the surface of lymphocytes.
		Forsdyke, D., in The Biological Effects of Phytohaemagglutinin (edit.
	www.nature.com /nature/journal/v219/n5158/abs/2191021a0.html (291 words)

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	psoriasis-connect.cba.pl /cure.natural_cancer_cure.html (6114 words)

	Phytohaemagglutinin and transfer factor in the leucocyte migration inhibition test in patients with sarcoidosis -- ...
		Phytohaemagglutinin and transfer factor in the leucocyte migration inhibition test in patients with sarcoidosis -- Morison 31 (1): 87 -- Thorax
		Phytohaemagglutinin and transfer factor in the leucocyte migration inhibition test in patients with sarcoidosis
		A new system of phytohaemagglutinin stimulation in vitro using the
	thorax.bmjjournals.com /cgi/content/abstract/31/1/87 (134 words)

	Glia Literature - Myelin basic protein inhibits the calcium response to phytohaemagglutinin in human lymphocytes. (Site not responding. Last check: 2007-10-23)
		Pre-treatment of human lymphocytes with myelin basic protein results in a lower rising of cytosolic concentration of free calcium after stimulation with phytohaemagglutinin.
		It is not due to a interaction between myelin basic protein and phytohaemagglutinin, but appears to be a consequence of the binding of the protein to the cell surface.
		The reduction of the rise of cytosolic calcium induced by phytohaemagglutinin is specific for the myelin basic protein because other proteins like albumin and protamine have no effect.
	www.glialcell.net /showabstract.php?pmid=1692750 (248 words)

	Lymphocyte transformation responses to phytohaemagglutinin and pokeweed mitogen in patients at differing stages of HIV ...
		Lymphocyte transformation responses to phytohaemagglutinin and pokeweed mitogen in patients at differing stages of HIV infection: are they worth measuring?
		The influence of disease stage on T lymphocyte subsets and lymphocyte transformation responses (LyTR) to phytohaemagglutinin (PHA) and Pokeweed mitogen was assessed.
		RESULTS--The median CD3 and CD4 counts and LyTR to PHA and Pokeweed mitogen were highest in patients with persistent generalised lymphadenopathy (PGL) and decreased progressively in the order: asymptomatic patients, those with ARC, those with AIDS.
	www.aegis.com /aidsline/1994/feb/M9420105.html (476 words)

	Phytohaemagglutinin induced proliferation of lymphocytes from patients with rheumatoid arthritis and iron deficiency -- ...
		Phytohaemagglutinin induced proliferation of lymphocytes from patients with rheumatoid arthritis and iron deficiency -- Polson et al.
		Phytohaemagglutinin induced proliferation of lymphocytes from patients with rheumatoid arthritis and iron deficiency
		such as phytohaemagglutinin (PHA) is commonly depressed in both rheumatoid
	ard.bmjjournals.com /cgi/content/abstract/47/7/570 (304 words)

	The mass of a murine non-Hodgkin lymphoma tumour is...
		The mass of a murine non-Hodgkin lymphoma tumour is reduced by phytohaemagglutinin - induced gut hyperplasia and feeding a protein-depleted diet
		AIM : In this investigation the aim was to study the growth characteristics of non-Hodgkin lymphoma (NHL) tumours in mice fed the plant lectin phytohaemagglutinin (PHA) in order to induce gut hyperplasia.
		KEY WORDS: non-Hodgkin lymphoma, tumour growth, non-protein diet, non-protein diet, hyperplasia, phytohaemagglutinin, lectin,.
	www.cancerprev.org /Journal/Issues/22/101/10/2593 (425 words)

	psoriasis-cure.cba.pl Present: / cure
		Medical publicize phytohaemagglutinin tragedy efficiently, stops 250 (5-8%), 49-7441-85125.
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	psoriasis-cure.cba.pl /cure.natural_cancer_cure.html (6647 words)

	Putrescine as a source of instant energy in the small intestine of the rat -- Bardócz et al. 42 (1): 24 -- Gut
		Rats (about 80 g), in groups of five, were given either phytohaemagglutinin- or lactalbumin-containing diets, fed
		Bardocz S, Brown DS, Grant G, Pusztai A. Luminal and basolateral polyamine uptake by rat small intestine stimulated to grow by Phaseolus vulgaris lectin phytohaemagglutinin in vivo.
		Small intestinal growth caused by feeding red kidney bean phytohaemagglutinin lectin to rats.
	gut.bmjjournals.com /cgi/content/full/42/1/24 (3398 words)

	Institutt for biokjemi og molekylærbiologi - 1994
		, K. Phytohaemagglutinin in the diet induces growth of the gut and modifies some organ weights in mice.
		ISSN 0269-8951 3 Bolstad, Anne Isine; Tommassen, J.; Jensen, H.B. Sequence variability of the 40-kDa outer membrane proteins of Fusobacterium nucleatum strains and a model for the topology of the proteins.
		ISSN 0304-3835 32 Pryme, I. F.; Pusztai, A. J.; Bardocz, S. The initial growth rate of Krebs II ascites cell tumours in mice is slowed down by the inclusion of phytohaemagglutinin in the diet.
	www.fou.uib.no /publ/94kort/49.html (1063 words)

	A Magyar Tudományos Akadémia Köztestületi Honlapja
		Kondorosi, E. and Kay, J. (1975) Changes in the lymphocyte calcium levels during activation by the ionophore A23187 and phytohaemagglutinin.
		Kondorosi, E. and Kay, J. (1977) The role of calcium in lymphocyte activation by the ionophore A23187 and phytohaemagglutinin.
		Duda, E. and Kondorosi, E (1980) Transformation of eucaryotic cells via liposome mediated microinjection.
	www.mtakoztest.hu /pub_kondorosi_eva.htm (4278 words)

	Monocyte-induced inhibition of lymphocyte response to phytohaemagglutinin in progressive systemic sclerosis -- Lockshin ...
		Monocyte-induced inhibition of lymphocyte response to phytohaemagglutinin in progressive systemic sclerosis -- Lockshin et al.
		Monocyte-induced inhibition of lymphocyte response to phytohaemagglutinin in progressive systemic sclerosis
		to phytohaemagglutinin (PHA) are abnormal (27.2 +/- 3.5 X 10(- 3) counts
	ard.bmjjournals.com /cgi/content/abstract/42/1/40 (256 words)

	Enhancement by phytohaemagglutinin of inactivation of herpes simplex virus by concanavalin A -- Ito and Barron 33 (2): ...
		Enhancement by phytohaemagglutinin of inactivation of herpes simplex virus by concanavalin A -- Ito and Barron 33 (2): 259 -- Journal of General Virology
		Enhancement by phytohaemagglutinin of inactivation of herpes simplex virus by concanavalin A
		Inactivation of herpes simplex virus (HSV) by concanavalin A (Con A) was
	vir.sgmjournals.org /cgi/content/abstract/33/2/259 (219 words)

	Institutt for biokjemi og molekylærbiologi - 1997
		34 Pryme, I.F; Grant, G; Bardocz, S; Pusztai, A Dietary phytohaemagglutinin stimulates gut hyperplasia, reduces tumour growth and modulates polyamine levels.
		35 Pryme, I.F; Bardocz, G; Grant, G; Pusztai, A Feeding of phytohaemagglutinin after injection of Krebs II cells is successful in reducing tumour growth.
		Feeding of phytohaemagglutinin after injection of Krebs II cells in successful in reducing tumour growth..
	www.fou.uib.no /publ/97kort/53.html (1457 words)

	Cytokine production of RSV/PHA-stimulated tonsillar mononuclear cells: influences of age and atopy -- Ichinohe et al. ...
		to RSV, the nonspecific mitogen phytohaemagglutinin (PHA) and
		The association of wheezing with RSV decreases significantly
		Table 1 Type-1, type-2 and pro-inflammatory cytokine production from tonsillar mononuclear cells stimulated for 24 h with phytohaemagglutinin (PHA), respiratory syncytial virus (RSV) and ultraviolet (UV)-inactivated RSV
	erj.ersjournals.com /cgi/content/full/22/2/317 (2809 words)

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