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Topic: Pilocarpine

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	Pilocarpine - Wikipedia, the free encyclopedia
		Pilocarpine is a muscarinic alkaloid obtained from the leaves of tropical American shrubs from the genus Pilocarpus.
		Pilocarpine has been used in the treatment of chronic open-angle glaucoma and acute angle-closure glaucoma for over 100 years.
		Pilocarpine is used to stimulate sweat glands in a sweat test to measure the concentration of chloride and sodium that is excreted in sweat.
	en.wikipedia.org /wiki/Pilocarpine (309 words)

	[No title] (Site not responding. Last check: 2007-10-14)
		Pilocarpine should be administered with caution in and under close medical supervision of patients with significant cardiovascular disease.
		Pilocarpine hydrochloride should be administered with caution to and under close medical supervision in patients with controlled asthma, chronic bronchitis, or chronic obstructive pulmonary disease requiring pharmacotherapy.
		The pharmacokinetics of orally administered pilocarpine in patients with renal and hepatic disease is not known.
	www.best-meds.com /druginfo/salagen_warnings.htm (796 words)

	Pilocarpine
		Pilocarpine augments the secretions of the nasal, pharyngeal and laryngeal mucous membranes, and, on this account, it is recommended by Guttman as a remedy to be used in treating diphtheria with the hope that the membrane may be more easily detached.
		Pilocarpine may be used as a substitute for eserine in diseases of the eye, since it, when locally applied, produces contraction of the pupil.
		The diseases for which pilocarpine may be prescribed are uremic poisoning, hydrothorax and dropsies of all kinds not having their origin in the heart; mumps, diphtheria and other inflammations of the throat, larynx and bronchi.
	www.harvestfields.ca /HerbBooks/01/01/114.htm (1502 words)

	epinephrine and pilocarpine ophthalmic
		Pilocarpine ophthalmic also reduces pressure in the eye by increasing the amount of fluid that drains from the eye.
		Together, epinephrine and pilocarpine are used to lower increased pressure in the eye that may be caused by conditions such as open-angle glaucoma and ocular (eye) hypertension (high pressure).
		The symptoms of an epinephrine and pilocarpine ophthalmic overdose are unknown.
	hw.healthdialog.com /kbase/multum/d03518a1.htm (1591 words)

	Pilocarpine nitrate
		Pilocarpine is used primarily in the treatment of open-angle glaucoma and detached retina where it is believed to be effective in the reduction of intra-ocular pressure.
		Pilocarpine is also indicated for the treatment of radiation induced xerostomia (dry mouth) in patients with cancer of the head and neck.
		Pilocarpine is also a stimulant to the excretory glands and can act to increase bodily secretions including bronchial, nasal, mammory, salivary and to reduce severe bodily sweating.
	www.linnea-worldwide.com /products/pilonitrate.asp (209 words)

	Pilocarpine
		Pilocarpin is used with increased caution in cases of severe heart failure, bronchial asthma, hyperthyroidism, peptic ulcer, disturbed urinary bladder emptying, stenotic changes in the gastrointestinal tract and urinary passages.
		During the treatment with Pilocarpin there is a possibility of visual disturbances, because of which driving and working with machines should be avoided.
		Pilocarpin is a direct parasymatholytic agent and directly acts on the M-cholinoreceptors.
	www.bpg.bg /sopharma/pilocarpine.phtml (381 words)

	Untitled Document
		Pilocarpine is an alkaloid extracted from the leaves of the Jaborandi plant (Pilocarpus mycrophyllus) in the Rutaceae family.
		Pilocarpine is a cholinergic drug and is administered in the treatment of xerostomy and other eye conditions along with a host of salivary production-related conditions.
		It was discovered that pilocarpine was responsible for much of the biological activity of the plant, in particular it’s ability to induce sweating and salivation, as well as to lower intraocular pressure in the eyes.
	www.phytomedical.com /Plant/Pilocarpine.asp (756 words)

	pilocarpine ophthalmic
		Pilocarpine ophthalmic reduces the pressure in the eye by increasing the amount of fluid that drains from the eye.
		Pilocarpine ophthalmic is used to treat glaucoma by lowering the pressure inside the eye.
		Pilocarpine ophthalmic is in the FDA pregnancy category C. This means that it is not known whether pilocarpine ophthalmic will harm an unborn baby.
	hw.healthdialog.com /kbase/multum/d01191a1.htm (1500 words)

	MedlinePlus Drug Information: Pilocarpine (Ophthalmic) (Site not responding. Last check: 2007-10-14)
		Pilocarpine (pye-loe-KAR-peen) is used to treat glaucoma and other eye conditions.
		However, it is not known whether pilocarpine passes into the breast milk.
		Although there is no specific information comparing use of pilocarpine in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/202465.html (1522 words)

	Pilocarpine - PetPlace.com (Site not responding. Last check: 2007-10-14)
		Pilocarpine is one of a number of topical agents used to treat glaucoma.
		Pilocarpine stimulates smooth muscles of the iris and ciliary body, resulting in pupil constriction and other changes that help in the removal of aqueous humor from the eye.
		Pilocarpine is used to treat primary glaucoma in non-inflamed eyes in dogs and cats.
	www.petplace.com /drug-library/pilocarpine/page1.aspx (868 words)

	Pilocarpine for Sjögren's syndrome - [Medication] - Quest Diagnostics Patient Health Library
		Pilocarpine increases the amount of saliva and tears produced by the salivary and tear glands.
		Pilocarpine tablets are used to relieve dryness in the mouth, throat, and eyes caused by Sjögren's syndrome.
		Pilocarpine has shown good results in relieving the dry mouth symptoms and, to a lesser extent, the dry eyes symptoms caused by Sjögren's syndrome.
	www.questdiagnostics.com /kbase/topic/detail/drug/uh1126/detail.htm (324 words)

	1800PetMeds.com - Pilocarpine 2% Ophthalmic Solution 15 Ml
		Pilocarpine is a miotic agent used in the treatment of canine primary glaucoma
		Pilocarpine is a miotic agent used in the treatment of canine primary glaucoma only.
		Pilocarpine is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice to use this medication in dogs.
	www.1800petmeds.com /pdetail.asp?SK=10258 (299 words)

	Salagen Side Effects, and Drug Interactions - Pilocarpine Hydrochloride - RxList Monographs
		Pilocarpine should be administered with caution to patients taking beta adrenergic antagonists because of the possibility of conduction disturbances.
		Drugs with parasympathomimetic effects administered concurrently with pilocarpine would be expected to result in additive pharmacologic effects.
		Pilocarpine might antagonize the anticholinergic effects of drugs used concomitantly.
	www.rxlist.com /cgi/generic3/salagen_ad.htm (765 words)

	SDZ ENS 163 a novel pilocarpine like drug: pharmacological in vitro and in vivo profile. Seizures produced by ... (Site not responding. Last check: 2007-10-14)
		The thiolactone analogue of pilocarpine, SDZ ENS 163, acts in vitro and in vivo as a partial agonist at M1/M3 and as an antagonist at M2 muscarinic receptors.
		Diazepam, 10 mg/kg, and scopolamine hydrochloride, 10 mg/kg, administered 30 min prior to the injection of pilocarpine, 380 mg/kg, prevented acute behavioral and electrographic, and long-term morphological and biochemical sequelae of seizures.
		The similarity of the topography of the damage and deficits in the GAD activity in brains of rats treated with pilocarpine indicates that GABAergic neurons are lost in the subregions of the brain preferentially sensitive to the convulsant action of pilocarpine.
	www.hairmillion.com /rx-online-info/scopolamine-online-rx/scopolamine-online-rx.429.html (844 words)

	epinephrine and pilocarpine ophthalmic Consumer Drug Information
		Epinephrine and pilocarpine ophthalmic is not commercially available in the United States.
		You may not be able to use epinephrine and pilocarpine ophthalmic, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
		Do not use epinephrine and pilocarpine ophthalmic without first talking to your doctor if you are pregnant or could become pregnant during treatment.
	www.drugs.com /MTM/epinephrine_and_pilocarpine_ophthalmic.html (1652 words)

	Pilocarpine Ophthalmic - Drugs & Vitamins - Drug Library - DrugDigest (Site not responding. Last check: 2007-10-14)
		PILOCARPINE (Isopto Carpine®, Pilocar®) makes a muscle in the eye tighten and increases the flow of fluid from the eye.
		There are three kinds of pilocarpine eye preparations: eye solution or drops, eye gel, or eye systems.
		Pilocarpine eye products are only for use in the eye.
	drugdigest.org /DD/DVH/Uses/0,3915,544\|Pilocarpine+Ophthalmic,00.html (701 words)

	Pilocarpine hydrochloride
		Product Origins: Extracted from the leaves of the South American plants Pilocarpus jaborandi and Pilocarpus microphyllus, Pilocarpine HCL is used predominantly for the treatment of eye disorders and has also recently been indicated for use in the treatment of dry mouth syndrome.
		Pilocarpine HCL is also indicated for the treatment of radiation induced xerostomia (dry mouth) in patients with cancer of the head and neck.
		Pilocarpine HCL is also a stimulant to the excretory glands and can act to increase bodily secretions including bronchial, nasal, mammory, salivary and to reduce severe bodily sweating.
	www.linnea-worldwide.com /products/pilohydro.asp (228 words)

	Pilocarpine Treatment of Xerostomia Induced by Psychoactive Medications
		We have empirically used pilocarpine in doses of 10—30 mg/day, divided into dosing of two or three times a day.
		The patients were generally pleased that their dry mouth symptoms responded rapidly, usually within 1 day, to pilocarpine treatment.
		Further investigation into the use of pilocarpine for the treatment of xerostomia induced by psychoactive medication seems warranted.
	www.oralcancerfoundation.org /news/story.asp?newsId=743 (396 words)

	9709 Pilocarpine/H&N
		Pilocarpine hydrochloride tablets are contraindicated in patients with uncontrolled asthma and in patients with known sensitivity to pilocarpine.
		Pilocarpine should be administered with caution in patients, and under dose medical supervision, with significant cardiovascular disease, controlled asthma, chronic bronchitis, or chronic obstructive pulmonary disease requiring pharmacotherapy.
		Pilocarpine administration must be reported on the followup forms as "non-protocol treatment" with start and stop dates as applicable.
	www.rtog.org /members/protocols/97-09/main.html (10574 words)

	pilocarpine - [Medication]
		Pilocarpine is an agent that affects the nervous system.
		Pilocarpine is used in the treatment of dry mouth.
		Pilocarpine is in the FDA pregnancy category C. This means that it is not known whether pilocarpine will be harmful to an unborn baby.
	www.peacehealth.org /kbase/multum/d04031a1.htm (955 words)

	Pilocarpine (Systemic) - MayoClinic.com
		Pilocarpine (pye-loe-KAR-peen) tablets are used to treat dryness of the mouth and throat caused by a decrease in the amount of saliva that may occur after radiation treatment for cancer of the head and neck or in patients with Sjogren's syndrome.
		Pilocarpine may also be used to treat dryness of the eyes caused by Sjogren's syndrome
		Studies on this medicine have been done only in adult patients and there is no specific information comparing use of pilocarpine in children with use in other age groups.
	www.mayoclinic.com /health/drug-information/DR202726 (1271 words)

	Oral Pilocarpine for Treatment of Opioid-induced Oral Dryness in Healthy Adults -- Götrick et al. 83 (5): 393 -- ...
		Oral pilocarpine for post-irradiation xerostomia in patients with head and neck cancer.
		A multicenter, randomized, double-blind, placebo-controlled, dose-titration study of oral pilocarpine for treatment of radiation-induced xerostomia in head and neck cancer patients.
		Pilocarpine tablets for the treatment of dry mouth and dry eye symptoms in patients with Sjogren syndrome: a randomized, placebo-controlled, fixed-dose, multicenter trial.
	jdr.iadrjournals.org /cgi/content/full/83/5/393 (2626 words)

	MedlinePlus Drug Information: Pilocarpine Ophthalmic
		Pilocarpine is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision.
		Pilocarpine comes in eyedrops, eye gel, and a controlled-release system (Ocusert Pilo).
		Pilocarpine controls glaucoma, but does not cure it.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682874.html (1108 words)

	Effectiveness of Vigabatrin against Focally Evoked Pilocarpine-Induced Seizures and Concomitant Changes in ...
		Vigabatrin and pilocarpine were dissolved in the microdialysis
		During intrahippocampal pilocarpine perfusion, a slowing of the rhythmic activity was recorded on the ECoG, indicated by the
		An inhibition of hippocampal GABA efflux during administration of pilocarpine was observed.
	jpet.aspetjournals.org /cgi/content/full/283/3/1239 (4713 words)

	Pilocarpine eye preparations - Patient UK (Site not responding. Last check: 2007-10-14)
		Pilocarpine works by opening up the drainage channels in the eye, allowing fluid to leave the eye and so relieving pressure.
		Pilocarpine can also be useful in treating other conditions which cause pressure in the eye.
		Pilocarpine may also contain hypromellose, which acts as artificial tears, for soothing the eyes.
	www.patient.co.uk /showdoc/30002217 (931 words)

	Pilocarpine (Ophthalmic) - MayoClinic.com (Site not responding. Last check: 2007-10-14)
		Ophthalmic pilocarpine may be absorbed into the body.
		Although there is no specific information comparing use of this medicine in children with use in other age groups, pilocarpine is not expected to cause different side effects or problems in children than it does in adults.
		Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
	www.mayoclinic.com /health/drug-information/DR202465 (1539 words)

	Clinical Trial: Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids
		It is not yet known whether pilocarpine is more effective than no further treatment for this condition.
		Evaluate the effectiveness of daily oral pilocarpine versus placebo in relieving dry mouth due to the ongoing use of an opioid for cancer related pain at 2 weeks by comparing proportion of patients with at least one response during the 2 week period, time of first response, and duration of first response.
		Evaluate the effect of pilocarpine on quality of life of this patient group.
	www.clinicaltrials.gov /ct/show/NCT00003686 (558 words)

	Pilocarpine - LoveToKnow 1911 (Site not responding. Last check: 2007-10-14)
		PILOCARPINE, C11H16N202, an alkaloid found, together with isopilocarpine and other related compounds, in the leaves of jaborandi (Pilocarpus pennatifolius).
		It was first isolated by E. Hardy in 1875 (Ber., 8, p.
		Jowett is of the opinion that pilocarpine and isopilocarpine are stereo-isomers of the structure: - 7CH N.
	www.1911encyclopedia.org /Pilocarpine (166 words)

	Pilocarpine oral - Patient UK (Site not responding. Last check: 2007-10-14)
		Take pilocarpine tablets with or immediately after food, with a large glass of water.
		Pilocarpine can cause you to sweat more than you usually do.
		Pilocarpine can cause blurred eyesight, particularly at night and in low lighting.
	www.patient.co.uk /showdoc/30003713 (679 words)

	Usefulness of basal and pilocarpine-stimulated salivary flow in primary Sjogren's syndrome. Correlation with clinical, ... (Site not responding. Last check: 2007-10-14)
		We hypothesize that the response of salivary glands to pilocarpine
		Oral pilocarpine for symptomatic relief of dry mouth and dry eyes in patients with Sjögren's syndrome.
		Pilocarpine tablets for the treatment of dry mouth and dry eye symptoms in patients with Sjögren syndrome.
	rheumatology.oxfordjournals.org /cgi/content/full/41/6/670 (2962 words)

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