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Topic: Plasma proteins

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In the News (Thu 24 May 18)

  BioMed Central | Full text | Plasma proteins in a standardised skin mini-erosion (II): effects of extraction pressure
The study was undertaken using the same subjects, materials and methods as described in: "Plasma proteins in a standardised skin mini-erosion (I): permeability changes as a function of time" [4].
The time course for the concentrations of the individual proteins was roughly similar in both extraction-pressure groups, indicating that the initial inflammatory stimulus was the determining factor.
Samples extracted with higher negative pressure contained a lower protein concentration at 0 h, indicating an increased water fraction and that the sieve function of the vascular wall was intact.
www.biomedcentral.com /1471-5945/2/4   (1440 words)

 BioMed Central | Full text | Plasma proteins in a standardised skin mini-erosion (I): permeability changes as a ...
For the individual proteins, the relative mean concentrations were 65 ± 36% for insulin, 48 ± 12% for albumin, 30 ± 19% for transferrin, 31 ± 15%for IgG and 19.5 ± 10% for alpha-2-macroglobulin.
Transport of plasma proteins over the endothelium from the vascular space to the interstitium is considered to be a passive process governed by the laws of convection and diffusion.
For the remaining proteins, the IF/plasma ratios at 0 h are similar for albumin and alpha-2-macroglobulin, whereas the ratios for prealbumin, transferrin and IgG are slightly lower than those found in other studies on interstitial fluid [13,17,18].
www.biomedcentral.com /1471-5945/2/3   (3630 words)

  Relationships between Seminal Plasma Proteins and Boar Fertility:
Previous studies indicated that the relative concentrations of two seminal plasma proteins were highly correlated with in vitro fertility of boar semen and could be used to rank boars in terms of their fertility when bred to sows (Flowers, 1998).
The relationship between the seminal plasma protein profile and boar fertility as measured by farrowing rates and number of pigs born alive is shown in Table 1.
As a result, quantification of the seminal plasma protein profile appears to be an excellent qualitative test for ranking boars prospectively in terms of their subsequent fertility.
mark.asci.ncsu.edu /swinereports/2001/03physflow.htm   (1579 words)

 1-01 Newsletter   (Site not responding. Last check: 2007-11-07)
Protein electrophoresis is a practical and useful test in assessing health status of psittacine birds.
It serves as the major reservoir of protein, is a main contributor of colloidal osmotic pressure, is involved in acid-base balance, and acts as a transport carrier for small molecules such as vitamins, minerals, hormones, fatty acids, and many drugs.
Pre-albumin is a separate and distinct plasma protein fraction that precedes albumin on electrophoresis, and is involved in the transportation of thyroid hormones.
www.antechdiagnostics.com /clients/antechNews/2001/1-01.htm   (1150 words)

 Blood Work: Science News Online, March 15, 2003
One protein that was missing was C-reactive protein, whose elevated presence in the blood may serve as a predictor of heart attacks (SN: 12/7/02, p.
The plasma donor's heart may have been so healthy that she had little C-reactive protein in her blood, or some facet of the group's approach may have obscured the protein's detection.
Once a low-abundance plasma protein is identified, it's still a formidable challenge to develop an inexpensive and effective assay to detect it or measure its concentration.
www.sciencenews.org /20030315/bob9.asp   (1776 words)

 Talecris Glossary
Hemophilia - Hemophilia is a genetic disorder characterized by the deficiency or absence of one of the proteins (or factors) in blood plasma that is responsible for clotting.
Plasma is the substance that remains after all blood cells are removed from blood.
These proteins are extracted from the plasma, purified, and used to manage serious and often life-threatening conditions.
www.talecris.com /1.7.6_glossary.aspx   (2538 words)

 The Interaction of Plasma Proteins and Platelets with a Homologous Series of Polyurethanes (SPE) (MPB archive, Jan 96)
Plasma composition was evaluated both before and after polymer exposure in order to determine the significant material factors affecting protein adsorption and ascertain the composition profile of the adsorbed protein layer.
The normalized optical density of the depleted protein was then compared with the normalized optical density of that same protein from a slab gel used to separate and evaluate the protein from the unexposed plasma control.
The pure-phase homopolymer had higher protein and platelet adsorption than did the higher-phase-purity PU-65-1000 and PU-65-2000 copolymers, indicating that a range of surface hard-segment concentrations may be important to optimize the structure of blood-compatible polyurethane applications.
www.devicelink.com /mpb/archive/96/01/004.html   (2271 words)

 NDI Terminology - proteins   (Site not responding. Last check: 2007-11-07)
Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages.
Twenty different amino acids are commonly found in proteins, and each protein has a unique, genetically defined amino acid sequence which determines its specific shape and function.
plasma proteins - The hundreds of different proteins present in blood plasma, including carrier proteins (such as albumin, transferrin, and haptoglobin), fibrinogen and other coagulation factors, complement components, immunoglobulins, enzyme inhibitors, precursors of substances such as angiotensin and bradykinin, and many other types of proteins.
www.ndif.org /Terms/proteins.html   (220 words)

 Avian Plasma Proteins   (Site not responding. Last check: 2007-11-07)
It serves as the major reservoir of protein, it is the main contributor of colloidal osmotic pressure, it is involved in acid-base balance, and it acts as a transport carrier for small molecules such as vitamins, minerals, hormones and fatty acids.
These proteins usually elevate during the acute phase of inflammatory disease, and therefore are helpful in the diagnosis and monitoring of many infectious diseases and other causes of chronic inflammation.
Serum proteins include all plasma proteins except the coagulation proteins, principally fibrinogen, which are eliminated by clot separation.
www.exoticpetvet.net /dvms/proteins.html   (1163 words)

 FBR Plasma Proteins Pocket Guide
Serum protein testing has been an integral, although underutilized, part of clinical laboratory science for many years.
Through an educational grant from Dade Behring, Inc., FBR has developed this 152-page guide on serum protein utility and interpretation for day to day use by practitioners and laboratorians.
The guide can be used on many different levels by medical students, residents, internists, specialists, etc. The guide is most helpful in deciding which tests to order for a suspected diagnosis; interpreting protein results already in a patient's chart and as a source of background material for serum protein testing.
www.fbr.org /publications/plasmaprot/plasmaprot.html   (299 words)

 Plasma Abundant Proteins - GenWay Biotech, Inc.
The majority of the clinically relevant biomarkers reside within the low-abundant plasma protein fraction.
Numerous studies have demonstrated that IgY immunoaffinity fractionation of plasma or serum is highly specific and reproducible.
Specific needs for fractionation of plasma proteins can be met by customizing mixture of different IgY microbeads against different target proteins.
www.genwaybio.com /gw_file.php?fid=3051   (559 words)

 Modeling exchange of plasma proteins between microcirculation and interstitium of the renal medulla -- Wang and Michel ...
ISF protein concentration is <10% of that in the plasma of the
of protein in the ISF and plasma of the vasa recta that is predicted
Distribution of plasma proteins in the DVR at different values of G. In the figure, protein concentration is normalized by its value at the entrance, and x is normalized L.
ajprenal.physiology.org /cgi/content/full/279/2/F334   (5443 words)

 Blood Plasma
The quantities of the constituents of serum are the same as those for plasma minus the small amount of clotting agents, such as fibrinogen, destroyed during the clotting process.
This is because most of the plasma protein molecules are too large to pass through the capillary walls into the interstitial area.
In addition to proteins and inorganic ions the blood plasma carries a wide range of substances in transit to various tissues throughout the body.
www.fortunecity.com /greenfield/rattler/46/blood5.htm   (661 words)

 The Human Plasma Proteome: History, Character, and Diagnostic Prospects -- Anderson and Anderson 1 (11): 845 -- ...
plasma proteome and distinct from the plasma proteins.
is caused by the protein abnormality, as in insulin-dependent
of plasma proteins from monozygotic twins are quantitatively
www.mcponline.org /cgi/content/full/1/11/845   (10296 words)

 Proteomic Analysis of Integral Plasma Membrane Proteins   (Site not responding. Last check: 2007-11-07)
Efficient methods for profiling proteins integral to the plasma membrane are highly desirable for the identification of overexpressed proteins in disease cells.
Avoiding contamination by subcellular organelles and cytosolic proteins is crucial to the successful proteomic analysis of integral plasma membrane proteins.
g of protein extracted from the affinity-enriched integral plasma membrane preparation led to the identification of 898 unique proteins, of which 781 were annotated with regard to their plasma membrane localization.
pubs.acs.org /cgi-bin/abstract.cgi/ancham/2004/76/i7/abs/ac0354037.html   (311 words)

 Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome -- Gole et al. 278 (5): 961 -- ...
Plasma proteins modified by nitration were immunoprecipitated with affinity-purified polyclonal anti-nitrotyrosine antibodies.
All plasma proteins immunoprecipitated with affinity-purified polyclonal anti-nitrotyrosine antibody were separated on a 10% SDS gel, transferred to nitrocellulose paper (NCP), and stained with monoclonal anti-nitrotyrosine antibody.
Immunoprecipitated plasma proteins (with anti-nitrotyrosine antibodies) from sepsis-induced ARDS patients (lanes 4, 6, 8, 10, and 12) or a control subject (lanes 3, 5, 7, 9, and 11) were probed independently with specific human antibodies against ceruloplasmin (lanes 3 and 4), transferrin (lanes 5 and 6), plasminogen (lanes 7 and 8),
ajplung.physiology.org /cgi/content/full/278/5/L961   (4845 words)

 Nitrated and Oxidized Plasma Proteins in Smokers and Lung Cancer Patients -- Pignatelli et al. 61 (2): 778 -- Cancer ...   (Site not responding. Last check: 2007-11-07)
Identification of nitrated and oxidized plasma proteins by immunoprecipitation and WB analyses.
An aliquot of 125 µg of plasma proteins was immunoprecipitated with mouse anti-NTYR monoclonal antibody.
An aliquot of 125 µg of plasma protein was derivatized with DNPH, and the DNPH-derivatized proteins were immunoprecipitated with rabbit anti-DNP antibody and examined by WB analyses using rabbit polyclonal antibodies against human fibrinogen.
cancerres.aacrjournals.org /cgi/content/full/61/2/778   (5580 words)

 Transport of plasma proteins across vasa recta in the renal medulla -- Zhang and Edwards 281 (3): 478 -- AJP - Renal ...
Transport of plasma proteins across vasa recta in the renal medulla -- Zhang and Edwards 281 (3): 478 -- AJP - Renal Physiology
Increasing the permeability of AVR to plasma proteins to 1 × 10
Protein transport processes across vasa recta vary according to the values of permeability to protein and of reflection coefficient to small solutes, as well as with medullary depth.
ajprenal.physiology.org /cgi/content/full/281/3/F478   (5591 words)

 RLO: Plasma Proteins and Drug Distribution
Most, but not all, plasma proteins are manufactured in the liver including albumins.
These are the most abundant and form about 60% of all plasma proteins.
Approximately 4% of plasma proteins, such as fibrinogen, have a clotting function whilst the remaining less than 1% are regulatory such as metabolic enzymes.
www.nottingham.ac.uk /nursing/sonet/rlos/bioproc/plasma_proteins/3.html   (109 words)

 Contribution of plasma proteins to splanchnic and total anabolic utilization of dietary nitrogen in humans -- Fouillet ...
Contribution of plasma proteins to splanchnic and total anabolic utilization of dietary nitrogen in humans -- Fouillet et al.
The retention subsystem consists of 6 compartments representing dietary N in splanchnic free AA (SA), dietary N in splanchnic constitutive proteins (SCP), dietary N in splanchnic exported plasma proteins (SEP), dietary N in plasma free AA (PL), dietary N in peripheral free AA (PA), and dietary N in peripheral proteins (PP).
The effect of dietary protein deficiency on albumin synthesis and on the concentration of active albumin messenger ribonucleic acid in rat liver.
ajpendo.physiology.org /cgi/content/full/285/1/E88   (5926 words)

 Apolipoprotein A-I binds to a family of bovine seminal plasma proteins -- Manjunath et al. 264 (28): 16853 -- Journal ...
Apolipoprotein A-I binds to a family of bovine seminal plasma proteins -- Manjunath et al.
cross-reacts in the radioimmunoassay of apoA-I. Furthermore, BSP proteins
Proteins of the Cauda Epididymal Fluid Associated With Fertility of Mature Dairy Bulls
www.jbc.org /cgi/content/abstract/264/28/16853   (717 words)

 Serum/Plasma Depletion with Chicken Immunoglobulin Y Antibodies for Proteomic Analysis from Multiple Mammalian Species ...
Seventy-five micrograms of Cibacron blue (albumin)-associated protein was subjected to 2DE on a pH 3–10 immobilized pH gradient strip and a 6%–15% SDS-containing polyacrylamide gel (A).
Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis.
Subproteomics analysis of phosphorylated proteins: Application to the study of B-lymphoblasts from a patient with Scott syndrome.
jbt.abrf.org /cgi/content/full/15/3/184   (2580 words)

 Identification of Amadori-Modified Plasma Proteins in Type 2 Diabetes and the Effect of Short-Term Intensive Insulin ...
A 1:10 dilution of culture filtrate (primary antibody) of clone HB-9644 and a 1:10,000 dilution of rabbit anti-mouse peroxidase-conjugated secondary antibody were used for the blot.
Plasma samples from a representative diabetic subject were chosen for performing two-dimensional gel electrophoresis followed by Western blot.
The corresponding gel spots were excised from the Coomassie blue-stained two-dimensional gels of respective samples and analyzed for protein identification by tandem mass spectrometry.
care.diabetesjournals.org /cgi/content/full/28/3/645   (3771 words)

 The Plasma Proteins in Normal Urine
With the aid of the moving-boundary technique, they demonstrated components with mobilities corresponding to those of the main protein fractions in serum.
It was found that all urine protein fractions, including the albumin, contained large amounts of carbohydrate, thus differing in composition from the corresponding plasma fractions.
Electrophoretic fractionation, therefore, does not give satisfactory information as to the types and amounts of plasma proteins present in normal urine.
www.nature.com /nature/journal/v187/n4739/abs/187776a0.html   (223 words)

 Effects of Cholesterol and Inflammation-Sensitive Plasma Proteins on Incidence of Myocardial Infarction and Stroke in ...   (Site not responding. Last check: 2007-11-07)
Plasma cholesterol (mean values and standard errors) in relation to number of inflammation-sensitive proteins in the top quartile.
Influence of plasma fibrinogen levels on the incidence of myocardial infarction and death is modified by other inflammation-sensitive proteins: a long-term cohort study.
Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events.
circ.ahajournals.org /cgi/content/full/105/22/2632   (2955 words)

 Scripps Laboratories: Company Profile
At the heart of Scripps Laboratories is protein purification.
Scripps Laboratories is a bulk manufacturer of high quality proteins and immunoreagents for the diagnostic industry and research community.
The Scripps product line includes a broad range of purified human hormones, cardiac markers, cancer markers, plasma and tissue proteins, monoclonal and polyclonal antibodies, as well as a number of animal hormones and additional biochemical reagents.
www.scrippslabs.com /company_profile.html   (298 words)

 Effect of Nonspecific Binding to Plasma Proteins on the Antithrombin Activities of Unfractionated Heparin, ...   (Site not responding. Last check: 2007-11-07)
Effect of Nonspecific Binding to Plasma Proteins on the Antithrombin Activities of Unfractionated Heparin, Low-Molecular-Weight Heparin, and Dermatan Sulfate -- Cosmi et al.
Effect of Nonspecific Binding to Plasma Proteins on the Antithrombin Activities of Unfractionated Heparin, Low-Molecular-Weight Heparin, and Dermatan Sulfate
plasma in the presence of LMWH is virtually identical to that
circ.ahajournals.org /cgi/content/abstract/95/1/118   (498 words)

 RLO: Plasma Proteins and Drug Distribution
The cellular components will have sunk to the bottom of the tube – they form about 45% of the sample.
The remaining 55% is the liquid we call plasma.
Most of it is water – about 92%, whilst plasma proteins form about 7%.
www.nottingham.ac.uk /nursing/sonet/rlos/bioproc/plasma_proteins/2.html   (101 words)

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