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Topic: Plasmapheresis

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	Plasmapheresis - Wikipedia, the free encyclopedia
		Plasmapheresis is the removal of (components of) blood plasma from the circulation.
		It is used as a therapy in particular diseases, and it is also a method by which blood donors donate only plasma, with remaining red cells and platelets returned to their circulatory systems, allowing up to twice weekly plasma donations.
		An important use of plasmapheresis is in the therapy of autoimmune disorders, where the symptoms are so catastrophic that medical therapy is insufficient in controlling the symptoms.
	en.wikipedia.org /wiki/Plasmapheresis (499 words)

	s030106a - Catastrophic Antiphospholipid Syndrome - Plasmapheresis (Site not responding. Last check: 2007-10-09)
		Anticoagulation was used in 70% of the patients, steroids in 70%, plasmapheresis in 40%, cyclophosphamide in 34%, intravenous gammaglobulins in 16%, and splenectomy in 4%.
		Plasmapheresis seems to be useful in several cases who had not responded to conventional therapy (heparin, steroids, immunosuppressive) directed against immunologically mediated intravascular thrombosis.
		Plasmapheresis is thought to be an influential strategy of treatment for patients with collagen vascular diseases.
	www.emory.edu /WHSCL/grady/amreport/litsrch02/s030106a.html (4524 words)

	[No title]
		The regulations require, inter alia, that a plasma center obtain the informed consent of donors before plasmapheresis is performed and that a licensed physician both examine a potential donor before he or she is accepted and be present on the premises while the procedure is being performed.
		Among those regulations are rules governing plasmapheresis, the process by which whole blood is removed from a donor, blood plasma is separated from the donor's whole blood, and the remaining blood components are returned to the donor.
		Plasmapheresis, which was not mentioned during the debates on the Act (see page 17 note 16, infra) and which is performed on a local basis, would thus not have been preempted by that Act.
	www.usdoj.gov /osg/briefs/1984/sg840044.txt (7161 words)

	Facts About Plasmapheresis \| MDA Publications
		Plasmapheresis is a process in which the fluid part of the blood, called plasma, is removed from blood cells by a device known as a cell separator.
		A small, thin tube (catheter) is placed in a large vein, usually the one in the crook of the arm, and another tube is placed in the opposite hand or foot (so that at least one arm can move freely during the procedure).
		Plasmapheresis is performed at many major medical centers across the country.
	www.mdausa.org /publications/fa-plasmaph.html (957 words)

	Process for pheresis procedure and disposable pheresis bowl therefor - Patent 4059108 (Site not responding. Last check: 2007-10-09)
		A unitary plasmapheresis centrifuge rotor in accordance with claim 13 wherein said means to divide said plasma reservoir into two chambers comprises a baffle extending through said plasma reservoir in a plane intersecting the axis of said rotor.
		A unitary plasmapheresis centrifuge rotor in accordance with claim 1 wherein said red cell reservoir has a volume sufficient to contain the mass of red cells derived form one unit of whole blood and said plasma reservoir has a volume sufficient to contain the plasma derived form at least two units of whole blood.
		A unitary plasmapheresis centrifuge rotor in accordance with claim 1 wherein the cross sectional configurations of said red cell and plasma reservoirs taken normal to the axis of rotation of said bowl are circular.
	www.freepatentsonline.com /4059108.html (7187 words)

	Plasmapheresis \| Principal Health News
		Plasmapheresis is a blood purification procedure used to treat several autoimmune diseases.
		Plasmapheresis is used to remove antibodies from the bloodstream, thereby preventing them from attacking their targets.
		Plasmapheresis requires insertion of a venous catheter, either in a limb or central vein.
	www.principalhealthnews.com /topic/topic100587306 (827 words)

	Centre for Health Evidence
		She states that plasmapheresis is effective in reducing the level of the antibodies responsible for the nephritis, and cites a number of trials that have suggested therapy is beneficial.
		Plasmapheresis must be compared with a control management strategy, and patients must be randomized to receive or not receive the plasmapheresis.
		One is a trial of prednisone and cyclophosphamide [1]; a second examines the effect of plasmapheresis on risk of infection [2].
	www.cche.net /usersguides/therapy.asp (7949 words)

	American Journal of Critical Care: Adjunctive use of plasmapheresis and intravenous immunoglobulin therapy in sepsis: a ... (Site not responding. Last check: 2007-10-09)
		Plasmapheresis has been available for decades and is most commonly used in treatment of systemic lupus erythematosus, myasthenia gravis, sickle cell crisis, (6) and oncological disorders such as lymphoma and multiple myeloma.
		Plasmapheresis is also known as plasma exchange because the plasma removed is replaced with albumin, fresh frozen plasma, or crystalloid fluid.
		Plasmapheresis may be used to treat sepsis related to necrotizing soft tissue infections.
	www.findarticles.com /p/articles/mi_m0NUB/is_2_14/ai_n13794933 (1338 words)

	Donating plasma
		In plasmapheresis, equipment is used to separate the blood into plasma and cells.
		The duration of plasmapheresis is longer than normal blood donation because the plasmapheresis consists of a number of repeated steps.
		Plasmapheresis is less taxing for the body than ordinary blood donation because the blood cells are given back to the donor.
	www.sanquin.nl /Sanquin-eng/sqn_donor_eng.nsf/0/17990B8D4C6ACDAFC1256EC1004DC6AB?OpenDocument&BaseTarget=Body (817 words)

	Blood Bank of the Redwoods (Site not responding. Last check: 2007-10-09)
		The Blood Bank of the Redwoods began the plasmapheresis (plasma-4-e-sis) collection program in July of 1998 to meet the needs of area hospital patients who are in need of this critical blood component.
		Plasmapheresis is the separation of the plasma from the rest of the blood and requires the use of a special apheresis machine.
		Plasmapheresis, like whole blood, only requires the use of one arm for donation.
	www.bbr.org /plasma.html (451 words)

	(BETA) Plasmapheresis for HIV Related Neuropathy
		Several studies suggest that plasmapheresis is a safe, effective treatment for some individuals with HIV related peripheral neuropathy, specifically those with either Guillain Barr syndrome* or CIDP.
		Plasmapheresis is not effective in treating HIV infected individuals with DSPN.
		In plasmapheresis, blood is circulated outside the individual, antibodies to the nerve tissue and plasma are removed, and the blood cells are then returned to the patient along with a replacement fluid.
	www.aegis.com /pubs/beta/1989/beta0307.html (452 words)

	Treatment for Enlarged Spleen, Plasmapheresis, and Other Control Measures
		A process called plasmapheresis, or plasma exchange, is used to thin the blood and provide rapid symptom relief from hyperviscosity syndrome.
		Plasmapheresis works by filtering the blood through a special machine that breaks the blood down into its components.
		Plasmapheresis is not an answer to hyperviscosity, however: after treatment, the blood will once more begin to thicken.
	www.waldenstroms-macroglobulinemia.com /html/treatment-and-control-of-wm.php3 (781 words)

	Plasmapheresis (Site not responding. Last check: 2007-10-09)
		During plasmapheresis (also called plasma exchange), these abnormal antibodies are removed from the bloodstream.
		Plasmapheresis is a procedure in which blood is separated into cells and plasma (liquid).
		The number of plasmapheresis treatments needed depends on the protocol the physician has determined is best for the patient.
	www.myasthenia.org /information/Plasmapheresis.htm (877 words)

	PedsCCM: EB Journal Club Review (Site not responding. Last check: 2007-10-09)
		Yes, apart from the plasmapheresis (and use of fresh frozen plasma), it appears that the two groups were treated equally as far as the use of surgery, inotropes and anticoagulation (see Table 2, page 1436).
		The number of patients needed to be treated with plasmapheresis to prevent one death was 4.9 (95% CI 2.5 to 50).
		As mentioned earlier the RR of mortality in the plasmapheresis group was 0.61 (95% CI = 0.39 to 0.97) Based on the data available the relative risk reduction for fatal outcome in the plasmapheresis group was 39% with the calculated 95% CI ranging from 3% to 61%.
	pedsccm.wustl.edu /EBJ/THERAPY/Busund-plasmaphersis.html (1411 words)

	Indian Pediatrics - Editorial
		Plasmapheresis was used after a course of steroid in all the series and case reports(5-7).
		These two cases demonstrated that plasmapheresis could be useful even in the fourth week in severe ADEM not responding to steroid therapy.
		Plasmapheresis is an option for IVIG resistant cases and those who cannot afford IVIG.
	www.indianpediatrics.net /may2005/may-479-482.htm (1298 words)

	Canada Gazette
		Plasmapheresis is a process by which blood is collected from a donor, the plasma portion is separated out and extracted, and the remaining non-plasma portion is returned to the donor.
		During plasmapheresis, the anticoagulant solution that is mixed with the blood collected from the donor must be an anticoagulant solution for which a drug identification number (DIN) has been assigned by Health Canada, indicating the solution is suitable for use in plasmapheresis.
		"plasmapheresis session" means an appointment between a fabricator and a donor during which the fabricator proceeds or intends to proceed with plasmapheresis.
	canadagazette.gc.ca /partI/2005/20050903/html/regle7-e.html (7648 words)

	Plasmapheresis (Site not responding. Last check: 2007-10-09)
		Plasmapheresis is a form of apheresis that involves selective removal of the patient's plasma, which is then replaced by special intravenous fluids.
		The best way to understand plasmapheresis is to think of it in terms of a continuous withdrawal of a small amount of blood, and then having that blood continuously returned without the antibodies that were causing the symptoms.
		The anticoagulant, which is added to the blood during plasmapheresis slows clotting for up to five hours after plasmapheresis is completed and may cause bleeding if the skin is cut.
	www.mgawpa.org /plasmapheresis.htm (1060 words)

	High PRA Rescue
		Plasmapheresis and immunoadsorption are two methods of removing antibody from the blood.
		Plasmapheresis is a treatment similar to hemodialysis in that it involves circulating part of the patient's blood through a machine.
		While results from prior clinical trials of plasmapheresis to prepare patients for kidney transplantation were encouraging, the high rates of rejection have generally discouraged its routine use in most transplant centers.
	www.umm.edu /transplant/kidney/highpra.html (1776 words)

	What is plasmapheresis
		Plasmapheresis is a relative safe procedure, but there are some risks associated with the treatment.
		Constant monitoring during the treatments allows the measurable benefits of plasmapheresis to outweigh its risks.
		You will be instructed to report any signs of numbness, tingling associated with the mouth, eyes, fingers or toes and leg cramps, dizziness and menstrual confusion which may indicate a low blood calcium or potassium level.
	members.rediff.com /wande/plasmapheresis.htm (654 words)

	Frequently Asked Questions
		Plasmapheresis is the separation of plasma from whole blood.
		Plasmapheresis allows the nurse to utilize existing skills in a challenging new manner and offers a comfortable alternative to hemodialysis.
		Unlike patients with chronic renal failure, patients who need plasmapheresis generally survive and return to normal activities of daily living, providing a new sense of job satisfaction to the nephrology nurse.
	www.apheresis.com /ques.html (1199 words)

	DONOR PLASMAPHERESIS
		Plasmapheresis was an essential element in the economic viability of the program.
		The unwanted red cells are returned to the donor either as a separate step at the session (called manual plasmapheresis) or as an integral part of the collection procedure (on-line plasma separation).
		The community fluent with the blood industry believes that misuse of this technology and the indiscriminate application of poorly controlled plasmapheresis systems, mishandled by improperly trained staff and unethical practices by some of the collection agencies contributed dramatically to the spread of blood-borne diseases in the eighties, in particular non-A and non-B hepatitis.
	implants.clic.net /tony/Corner1/062.htm (796 words)

	IVIG and Plasmapheresis
		Plasmapheresis: Plasma is the fluid portion of the blood that contains the diseased antibodies attacking other healthy cells in the body (i.e., the myelin and nerves).
		Plasmapheresis is a process that separates the blood cells; red cells, white cells, and platelets, from the blood plasma so the plasma can be removed.
		The patient is given a fluid called Albumin (the same volume of plasma removed and given at the same rate during removal) made of 5-10% blood serum and IV fluids.
	www.aboutgbs.com /IVIG_and_Plasmapheresis.htm (549 words)

	National MS Society \| Sourcebook: Plasmapheresis (Plasma Exchange) (Site not responding. Last check: 2007-10-09)
		It is not clear whether plasmapheresis is of benefit in the short- or long-term treatment of MS, and its use in MS remains controversial.
		An exacerbation-also known as an attack, relapse, or flare-is a sudden worsening of an MS symptom or symptoms, or the appearance of new symptoms, which lasts at least 24 hours and is separated from a previous exacerbation by at least one month.
		In this multicenter study, 116 patients having an exacerbation received ACTH and immunosuppressant medication, and either plasmapheresis or "sham" plasmapheresis (in which the plasma withdrawn from the patient was returned, instead of being replaced).
	www.nationalmssociety.org /Sourcebook-Plasmapheresis.asp (551 words)

	Plasma Exchange (Plasmapheresis)
		Apheresis is a general term describing removal of blood from a subject; a portion of the blood is separated and retained while the rest is returned to the donor.
		Plasmapheresis, in which plasma is separated and manipulated in a variety of ways, is probably the most common type of apheresis procedure.
		Although plasmapheresis was associated with an acute drop in the autoantibody titer, only two patients showed a minor improvement in neurologic symptoms.
	www.regence.com /trgmedpol/medicine/med05.html (3560 words)

	Plasmapheresis
		Plasmapheresis is a procedure in which blood is separated into cells and plasma.
		Plasmapheresis is a relatively safe procedure and constant monitoring during treatment allows the measurable benefits to out-weigh the risks.
		However, you may experience and will be instructed to report any signs of numbness, tingling associated with the mouth, eyes, fingers or toes and leg cramps, dizziness and mental confusion which may indicate a low blood calcium or potassium level.
	www.mgauk.org /main/gil5.htm (614 words)

	plasmapheresis on Encyclopedia.com (Site not responding. Last check: 2007-10-09)
		MED5 Plasmapheresis in the preoperative management of a patient with severe hyperthyroidism.
		Acute disseminated encephalomyelitis in children: discordant neurologic and neuroimaging abnormalities and response to plasmapheresis.
		Adjunctive use of plasmapheresis and intravenous immunoglobulin therapy in sepsis: a case report.(CE Online)(continuing medical education)
	www.encyclopedia.com /html/x/x-plasmaph.asp (270 words)

	Plasmapheresis definition - Cancer information on MedicineNet.com
		Plasmapheresis: A procedure designed to deplete the body of blood plasma (the liquid part of the blood) without depleting the body of its blood cells.
		Whole blood is removed from the body, the plasma is separated from the cells, the cells are suspended in saline, a plasma substitute or donor plasma), and the reconstituted solution may be returned to the patient.
		The procedure is used to remove excess antibodies from the blood in lupus, multiple sclerosis, multiple myeloma, etc. Plasmapheresis carries with it the same risks as any intravenous procedure.
	www.medterms.com /script/main/art.asp?articlekey=4937 (234 words)

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