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Topic: Plasmodium falciparum

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	Plasmodium falciparum - Wikipedia, the free encyclopedia
		Plasmodium falciparum is a protozoan parasite, one of the species of Plasmodium that cause malaria in humans.
		Malaria is caused by infection with protozoa of the genus Plasmodium.
		Plasmodium falciparum is often used an example for evolution.
	en.wikipedia.org /wiki/Plasmodium_falciparum (1452 words)

	Chloroquine-Resistant Plasmodium falciparum:
		falciparum is the one associated with the highest morbidity and mortality.
		falciparum infection is characterized by a high degree of parasitemia, causing death through complications such as renal failure, severe hemolysis and anemia, pulmonary edema, and a variety of serious neurologic abnormalities.
		Preliminary studies on the response of Plasmodium falciparum to chloroquine in the Philippines, with the in vitro technique.
	www.kfshrc.edu.sa /annals/172/97-017.html (1394 words)

	Plasmodium falciparum (Site not responding. Last check: 2007-11-04)
		The Plasmodium falciparum parasite causes the most severe form of malaria, and is found in many tropical and subtropical regions of the world.
		Plasmodium falciparum is one of four distinct species of the malaria parasite that affect humans, of which two predominate as threats to public health.
		When an female mosquito infected with Plasmodium falciparum feeds on a human, parasites in the 'sporozoite' stage enter the bloodstream, are carried to the liver and infect liver cells.
	malaria.wellcome.ac.uk /doc_WTD023865.html (459 words)

	Plasmodium falciparum Spatial Analysis, Kenya \| CDC EID
		falciparum parasite density clustering, as shown in Figures 5 and 6, suggest a relationship between a house's distance from the Yala River and clustering of high parasite densities.
		falciparum malaria in school children in the low-altitude region of Lake Victoria basin (elevation ≈1,200 m) adjacent to the highlands reaches >80% (31–34), which is much higher than malaria prevalence in the highlands.
		Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya.
	www.cdc.gov /ncidod/eid/vol11no10/05-0106.htm (4519 words)

	Malaria
		Malaria is caused by protozoan parasites of the genus Plasmodium.
		falciparum is the most widespread and dangerous of the four: untreated it can lead to fatal cerebral malaria.
		Plasmodium develops in the gut of the mosquito and is passed on in the saliva of an infected insect each time it takes a new blood meal.
	www-micro.msb.le.ac.uk /224/Malaria.html (1219 words)

	Diagnosis: Plasmodium falciparum - Guide to Malaria (Site not responding. Last check: 2007-11-04)
		Plasmodium falciparium rates second in prevalence and is chiefly a tropical species.
		The red cell membranes express new adhesive protein and adhere to the endothelial cell; red cell obstruction of the microcirculation in addition to hemolysis may be responsible for acute life-threatening symptoms.
		This is Plasmodium falciprum on a thin smear with multiple small rings in normal sized red blood cells.
	www.gomcl.com /malaria/Falcip.htm (250 words)

	Plasmodium - Wikipedia, the free encyclopedia
		In 1898 Ronald Ross demonstrated the existence of Plasmodium in the stomach of the Anopheles mosquito.
		Plasmodium falciparum (the cause of malignant tertian malaria)
		Plasmodium malariae (the cause of benign quartan malaria)
	en.wikipedia.org /wiki/Plasmodium (399 words)

	Plasmodium (the genus of pathogens causing malaria)
		The pathogens causing malaria are four species of Plasmodium and they are transmitted from person to person by mosquitoes of the genus Anopheles.
		Plasmodium falciparum needs an average ambient temperature of at least 20ºC so is found mainly in warmer parts of the world.
		This gene encodes a peptide that seems to block receptors in the gut and salivary glands of the mosquito that are used by Plasmodium for replication.
	www.museums.org.za /bio/apicomplexa/plasmodium.htm (1387 words)

	Gametocytogenesis : the puberty of Plasmodium falciparum \| Malaria Journal, Volume 3 - Mirror @ Uni Potsdam
		Gametocytogenesis : the puberty of Plasmodium falciparum
		falciparum are absent from the peripheral circulation, due to the adherence of infected erythrocytes to microvascular endothelia of many organs and tissues such as heart, lung, liver, skin and brain [48].
		Hayward RE: Plasmodium falciparum phosphoenolpyruvate carboxykinase is developmentally regulated in gametocytes.
	bmc.ub.uni-potsdam.de /1475-2875-3-24/text.htm (7311 words)

	Malaria Journal \| Full text \| Antioxidant defense in Plasmodium falciparum- data mining of the transcriptome
		falciparum is capable of de novo synthesis of glutathione and of its recycling [12,13].
		Two genes putatively coding for such pumps have been identified in the falciparum genome and their functioning can perhaps be inferred from the ability of the free parasite and the IRBC to release GSH/GSSG to the extracellular medium [12,13,20].
		falciparum [8] has revealed two major parameters that characterize functional clusters of genes, the time of peaking and the amplification of gene transcription (expressed as peak-to-trough amplitude of the expression profile).
	www.malariajournal.com /content/3/1/23 (5098 words)

	Medmicro Chapter 83
		Malaria is caused by protozoa of the genus Plasmodium.
		In the case of falciparum malaria (the form that causes most deaths), infected erythrocytes adhere to the endothelium of capillaries and postcapillary venules, leading to obstruction of the microcirculation and local tissue anoxia.
		Diagnosis of malaria by detection of Plasmodium falciparum HRP-2 antigen with a rapid dipstick antigen-capture assay.
	gsbs.utmb.edu /microbook/ch083.htm (5653 words)

	Malaria: Parasitic Infections: Merck Manual Home Edition
		A decrease in the level of sugar (glucose) in the blood can occur in people infected with Plasmodium falciparum and may be severe in people who have a large number of parasites in their blood—particularly if they are treated with the drug quinine.
		Falciparum malaria, caused by Plasmodium falciparum, is the most dangerous form of malaria and can be fatal.
		In falciparum malaria, the infected red blood cells often stick to the walls of small blood vessels and clog them, resulting in damage to many organs—particularly the brain (cerebral malaria), lungs, and kidneys.
	www.merck.com /mmhe/au/print/sec17/ch196/ch196h.html (1402 words)

	The Plasmodium falciparum Genome Database (PFDB)
		The International Malaria Genome Sequencing Consortium was formed in 1996 to sequence the genome of the human malaria parasite Plasmodium falciparum, clone 3D7.
		Plasmodium falciparum Chromosome 2 Access to the latest version of the sequence data and annotation for Plasmodium falciparum Chromosome 2.
		Preliminary Annotation on Plasmodium falciparum Chromosomes 10, 11 and 14.
	www.tigr.org /tdb/edb/pfdb/pfdb.html (232 words)

	Malaria
		This landmark achievement is accompanied by the complete sequence of Plasmodium yoelii, the infectious agent in rodent malaria, providing the malaria community with both a human pathogen and its animal model simultaneously.
		Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13
		Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14
	www.nature.com /nature/malaria (563 words)

	Microscopy of Plasmodium species (Site not responding. Last check: 2007-11-04)
		Trophozoites - Plasmodium falciparum: Early trophozoites have the characteristic signet ring shape.
		falciparum is the presence of multiple trophozoites in one cell.
		Gametocyte - Plasmodium falciparum: The gametocytes of P.
	www.msu.edu /course/zol/316/psppscope.htm (208 words)

	Update: Chloroquine-Resistant Plasmodium falciparum -- Africa
		The first confirmed cases of chloroquine-resistant Plasmodium falciparum acquired in Africa were reported in 1978 (1) and occurred in non-immune travelers who had been in East Africa for relatively short periods of time.
		Plasmodium malaria resistant to chloroquine in a Zambian living in Zambia.
		Response of falciparum malaria to a standard regimen of chloroquine in Khartoum province, Sudan.
	www.cdc.gov /mmwr/preview/mmwrhtml/00000128.htm (631 words)

	Plasmodium in human blood cells, malaria, molecular models
		falciparum infections are the most serious of the four.
		Plasmodium ovale is the rarest of the four species and is apparently more restricted in distribution.
		Plasmodium vivax may cause relapses years later because of secondary exoerythrocytic cycles.
	www.buddycom.com /cells/malaria (566 words)

	SGTC :: plasmodium falciparum chromosome 12 ::
		The sequencing of Plasmodium falciparum chromosome 12 (clone 3D7) began in 1997 and was successfully completed in 2002 with a publication in Nature.
		All of the P. falciparum genome sequence data generated within the Malaria Genome Consortium is available at PlasmoDB.
		Genome sequence of the human malaria parasite Plasmodium falciparum.
	sequence-www.stanford.edu /group/malaria/index.html (186 words)

	Medical Dictionary: Plasmodium falciparum - WrongDiagnosis.com
		Plasmodium falciparum: A species of protozoa that is the causal agent of falciparum malaria (MALARIA, FALCIPARUM).
		Plasmodium falciparum : species of protozoa that is the causal agent of falciparum malaria; it is most prevalent in the tropics and subtropics.
		Plasmodium falciparum: Type of or association with medical condition Malaria.
	www.wrongdiagnosis.com /medical/plasmodium_falciparum.htm (344 words)

	Malaria Journal \| Full text \| In vivotranscriptional profiling of Plasmodium falciparum
		falciparum gene expression patterns, particularly the subset of genes that are specifically expressed in the in vivo state may identify unique parasite biology when it resides in the host environment.
		falciparum's predicted genes have not been found to be expressed in any of the life cycle stages previously studied [9].
		To maximize parasite transcript detection, 15 μg to 120 μg of cRNA were hybridized to the array and a quantitative expression level was calculated using the MOID algorithm for the Plasmodium genes on the array [2].
	www.malariajournal.com /content/3/1/30 (3615 words)

	Plasmodium falciparum genome data and search tips
		Alignment of Plasmodium yoeli proteins to the Plasmodium falciparum genomic sequence.
		falciparum to the preliminary annotation of whole shotgun sequences of P.yoelii, and to identify the reciprocal best hits.* The P.yoelii proteins are positioned in order of their best matches in P.
		In addition, the percent identity shown in the "alignment" column of the display (when the Py protein map is the master map) is for the local alignment region, not for the complete protein sequence.
	web.ncbi.nlm.nih.gov /mapview/static/malsearch.html (2086 words)

	A Plasmodium falciparum Homologue of Plasmodium vivax Reticulocyte Binding Protein (PvRBP1) Defines a Trypsin-resistant ...
		Plasmodium falciparum field isolates commonly use erythrocyte invasion pathways that are independent of sialic acid residues of Glycophorin A. Infect.
		Identification of proteins from Plasmodium falciparum that are homologous to reticulocyte binding proteins in Plasmodium vivax.
		Plasmodium falciparum homologue of the genes for Plasmodium vivax and Plasmodium yoelii adhesive proteins, which is transcribed but not translated.
	www.jem.org /cgi/content/full/194/11/1571 (6460 words)

	eMedicine - Malaria : Article by Johanna P Daily, MD
		P falciparum and P vivax are responsible for the majority of new infections.
		The periodicity of fever associated with each species (ie, 48 h for P falciparum, P vivax, and P ovale; 72 h for P malariae) is not apparent during initial infection because of multiple broods emerging in the blood stream.
		In the United States, patients with P falciparum are often treated on an inpatient basis in order to observe for complications attributable to either the illness or its treatment.
	www.emedicine.com /med/topic1385.htm (5503 words)

	Malaria. Plasmodium falciparum. Synonymous Mutations and Low complexity Segments
		falciparum chromosome 2 encoding MSP-4, MSP-5 and MSP-2 (GenBank: PFB310c, PFB305c, and PFB0300c).
		falciparum proteins are longer than their homologs in other species by virtue of their content of such low complexity segments that have no known function; these are interspersed among segments of higher complexity to which function can often be ascribed.
		falciparum genes have low complexity segments and there is a close correlation between gene length and the combined lengths of these segments in a gene.
	post.queensu.ca /~forsdyke/pfalcip01.htm (8941 words)

	Plasmodium falciparum Genome Project (Site not responding. Last check: 2007-11-04)
		The final sequence was verified by analysis of the known STS dataset derived from the Malaria Mapping Project (Jenny Thompson & Alan Cowman, WEHI) and the Genetic Mapping Initiative (Xin-zhaun Su & Tom Wellems, NIH).
		Sequence of Plasmodium falciparum chromosomes 1, 3 - 9 and 13
		Garder et al., Genome sequence of the human malaria parasite Plasmodium falciparum.
	www.sanger.ac.uk /Projects/P_falciparum/chr3 (120 words)

	The cytoplasmic domain of the Plasmodium falciparum ligand EBA-175 is essential for invasion but not protein ...
		Falciparum malaria parasites invade erythrocytes that lack glycophorin A and B (MkMk).
		Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations.
		A novel ligand from Plasmodium falciparum that binds to a sialic acid-containing receptor on the surface of human erythrocytes.
	www.jcb.org /cgi/content/full/162/2/317 (6961 words)

	Quinine, Plasmodium falciparum
		Malaria is caused by a parasite plasmodium vivax, which is carried by mosquitoes in tropical climates.
		One of the most deadly strains is Plasmodium falciparum.
		The Plasmodium parasite has a highly specialised and intricate life cycle, which involves both sexual and asexual stages, and so requires different hosts for completion.
	www.earthtym.net /ref-quinine.htm (1663 words)

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