Where results make sense

About us   |   Why use us?   |   Reviews   |   PR   |   Contact us

Plasmodium knowlesi - Wikipedia, the free encyclopedia Plasmodium knowlesi is a primate malaria parasite commonly found in Southeast Asia. A fifth of the cases of malaria diagnosed in Sarawak, Malaysia are due to P. knowlesi infections is diagnosed by examining thick and thin blood films in the same way as other malarias. en.wikipedia.org /wiki/Plasmodium_knowlesi   (316 words)

Simian Malaria in Humans | CDC EID knowlesi is prevalent among crab-eating macaques, Macaca fascicularis, in the Malaysian peninsula and the Philippines (2,10). knowlesi was not reported until 1965 (6); the patient was infected in a Malaysian forest. knowlesi could contribute to the reemergence of simian malaria in Thailand and southeast Asia, where its vectors, Anopheles leucosphyrus group, are abundant (15). www.cdc.gov /Ncidod/eid/vol10no12/04-0293.htm   (1809 words)

Memórias on line knowlesi are from 26 to 30 h and from 22 to 25 h, respectively. knowlesi parasites, from samples taken at different times during a 34-h period, initiated with naturally synchronous intra-erythrocytic ring stages are shown in Fig. knowlesi cultures with early ring stage parasites resulted in maturation of maximum number of schizonts in vitro at the 25th h. memorias.ioc.fiocruz.br /976/4438.html   (1663 words)

Aley Publications Identification of parasite proteins in a membrane preparation enriched for the surface membrane of erythrocytes infected with Plasmodium knowlesi. Plasmodium falciparum malaria: Cytoadherence of infected erythrocytes to endothelial cells and associated changes in the erythrocyte membrane. Atkinson, C.T., Aikawa, M., Aley, S.B., and Hollingdale, M.R., 1989, Expression of Plasmodium berghei circumsporozoite antigen on the surface of erythrocytic schizonts and merozoites. academics.utep.edu /Default.aspx?tabid=23137   (1119 words)

Plasmodium - Wikipedia, the free encyclopedia In 1898 Ronald Ross demonstrated the existence of Plasmodium in the wall of the midgut and salivary glands of a Culex mosquito. The sporozoites migrate to the liver and invade hepatocytes. It is thought that Plasmodium evolved from a parasite spread by the orofaecal route which infected the intestinal wall. en.wikipedia.org /wiki/Plasmodium   (2300 words)

Cytokine responses during acute simian Plasmodium cynomolgi and Plasmodium knowlesi infections -- Praba-Egge et al. 67 ... Cytokine responses during acute simian Plasmodium cynomolgi and Plasmodium knowlesi infections -- Praba-Egge et al. Plasmodium cynomolgi (P. vivax-like) and P. knowlesi (P. falciparum-like) infections in the rhesus monkey were used as a model to test the hypothesis that initial acute infection stimulates type 1/pro-inflammatory cytokine expression followed by a gradual type 2/anti-inflammatory response upon re-infection. The immune response to P. cynomolgi infection in rhesus monkeys seemed to be mediated by anti-parasite, pro-inflammatory responses during primary infection with a transition to protective type 2 responses after repeat infection. www.ajtmh.org /cgi/content/abstract/67/6/586   (337 words)

The Plasmodial Surface Anion Channel Is Functionally Conserved in Divergent Malaria Parasites -- Lisk and Desai 4 (12): ... knowlesi PSAC is the predominant conductive pathway in the infected rhesus RBC membrane. Transport of lactate and pyruvate in the intraerythrocytic malaria parasite, Plasmodium falciparum. Increased choline transport in erythrocytes from mice infected with the malaria parasite Plasmodium vinckei vinckei. ec.asm.org /cgi/content/full/4/12/2153   (4000 words)

MEDLINE Search on Medscape.com Plasmodium, the causative agent of malaria, has to undergo sexual differentiation and development in anopheline mosquitoes for transmission to occur. The dynamics of interactions between Plasmodium and the mosquito: a study of the infectivity of Plasmodium berghei and Plasmodium gallinaceum, and their transmission by Anopheles stephensi, Anopheles gambiae and Aedes aegypti. Recombinant expression and enzymatic subsite characterization of plasmepsin 4 from the four Plasmodium species infecting man. Plasmepsin 4 from Plasmodium falciparum and orthologs from Plasmodium malariae, Plasmodium ovale and Plasmodium vivax have been expressed in recombinant... search.medscape.com /uslclient/searchMedline.do?queryText=Plasmodium   (449 words)

Plasmodium Summary Plasmodium is a genus of protozoa that has a life cycle that includes a human host and a mosquito. The fever tends to be cyclical, reflecting the cyclical pattern of protozoan release from red blood cells followed by a period of protozoan multiplication inside other red blood cells. Resistance of the protozoa, particularly Plasmodium falciparum, to the drugs such as chloroquinine and pyrimethamine that have previously been an effective control was first reported in 1961. www.bookrags.com /Plasmodium   (775 words)

Plasmodium knowlesi Provides a Rapid In Vitro and In Vivo Transfection System That Enables Double-Crossover Gene ... Altered expression of Plasmodium knowlesi variant antigen on the erythrocyte membrane in splenectomized rhesus monkeys. Transmission of the H strain of Plasmodium knowlesi by Anopheles balabacensis balabacensis. Isolation of a new strain of Plasmodium knowlesi. iai.asm.org /cgi/content/full/70/2/655   (3779 words)

Malaria vaccine - Patent 4466917 Malaria is a severely debilitating, widespread disease caused by infection by a parasite of the genus Plasmodium. In particular, the choice of transfer vectors and expression vectors having advantageous properties such as high rates of expression, secretion of the expressed protein through the cell membrane, maximum stability, maximum antigenicity of the fusion protein, and the like, is deemed a matter of ordinary skill within the scope of the present invention. Specific examples directed to specific vectors, microorganisms and Plasmodium species are intended to illustrate the practice of the invention, and not to limit the scope thereof. www.freepatentsonline.com /4466917.html   (8019 words)

Stable transfection of malaria parasite blood stages -- van Dijk et al. 268 (5215): 1358 -- Science A plasmid transfection vector carrying the gene locus that encodes a drug-resistant form of the bifunctional enzyme dihydrofolate reductase-thymidylate synthase from the rodent malaria parasite Plasmodium berghei was constructed. Topology and replication of a nuclear episomal plasmid in the rodent malaria Plasmodium berghei. An alteration in concatameric structure is associated with efficient segregation of plasmids in transfected Plasmodium falciparum parasites. www.sciencemag.org /cgi/content/abstract/268/5215/1358   (868 words)

EXPERIMENTAL INFECTION OF THE OLIVE BABOON (PAPIO ANUBIS) WITH PLASMODIUM KNOWLESI: SEVERE DISEASE ACCOMPANIED BY ... Plasmodium knowlesi: persistence of transmission blocking immunity in monkeys immunized with gamete antigens. Infection of the squirrel monkey Saimiri sciureus, with Plasmodium knowlesi. Plasmodium knowlesi provides a rapid in vitro and in vivo transfection system that enables double-crossover gene knockout studies. www.ajtmh.org /cgi/content/full/69/2/188   (2809 words)

Protozoal antigen - Patent 4837016 A protection-inducing fragment of an antigen of Plasmodium falciparum, as defined in claim 1, the fragment having an apparent molecular weight of 1.50.times.10.sup.5 and an isoelectric point of 5.2. The malaria parasites are protozoa belonging to the genus Plasmodium. The available data on P. knowlesi and P. falciparum do not allow definite conclusions as to the developmental stage(s) at which parasite specific antigens are immunogenic or whether the antigens detected are the ones involved in protective immunity (Schmidt-Ullrich et. www.freepatentsonline.com /4837016.html   (5303 words)

Emory Vaccine Center :: Mary Galinski, Ph.D. Barnwell, J.W., Galinski, M.R., Desimone, S.G., Perler, F. and Ingravallo, P. Plasmodium vivax, P. cynomolgi and P. knowlesi: Identification of homologue proteins associated with the surface of merozoites. Vargas, E. L., Barnwell, J. W., Ingravallo, P., Perler, F. and Galinski, M. A merozoite surface protein of Plasmodium vivax that is a target of invasion inhibitory antibodies is orthologous to p101/ABRA of P. falciparum. Black, C. G., Barnwell, J. W., Huber, C. Galinski, M., and Coppel, R. The Plasmodium vivax homologues of Merozoite Surface Proteins 4 and 5 from Plasmodium falciparum are expressed at different locations in the merozoite. www.vaccines.emory.edu /scientists/galinski_pubs.shtml   (573 words)

Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an ... Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion -- Swardson-Olver et al. Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion Plasmodium yoelii: effects of red blood cell modification and antibodies on the binding characteristics of the 235 kD rhoptry protein. www.bloodjournal.org /cgi/content/full/99/8/2677   (5672 words)

Cell Biology of Plasmodium The C-terminal regions of Plasmodium TRAP and Toxoplasma MIC2 are functionally homologous (Kappe 1999). Beeson JG, Brown GV (2002) Pathogenesis of Plasmodium falciparum malaria: the roles of parasite adhesion and antigenic variation. Zieler H, Dvorak JA (2000) Invasion in vitro of mosquito midgut cells by the malaria parasite proceeds by a conserved mechanism and results in death of the invaded midgut cells. www.tulane.edu /~wiser/malaria/cmb.html   (4373 words)

MPM 2006   (Site not responding. Last check: 2007-11-04) Plasmodium knowlesi is primarily a simian malaria parasite. This discovery was a key breakthrough that led to the characterisation of antigenic variation in other Plasmodium species. This family belongs to the PIR superfamily (Plasmodium Interspersed Repeats), found at least in 6 Plasmodium species. www.mbl.edu /mpm/mpm-2006/abstracts/abstract.php?id=155   (296 words)

From Malaria to Chemokine Receptor: The Emerging Physiologic Role of the Duffy Blood Group Antigen -- Hadley and Peiper ... Unlike the 135-kD Duffy binding protein of P knowlesi, the 140-kD Duffy binding protein of P vivax does not bind to rhesus RBCs, a cell type that cannot be invaded by P vivax. Immunohistochemical studies localized the Duffy binding protein of P knowlesi to the micronemes, specialized organelles at the apical end of the parasite (merozoite) that appear to function in the process of invasion. Leech JH, Barnwell JW, Miller LH, Howard RJ: Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes. www.bloodjournal.org /cgi/content/full/89/9/3077   (9885 words)

The Individualist: Duffy blood group system On erythrocytes the Duffy antigen acts as a receptor for invasion by the human malarial parasites Plasmodium vivax and Plasmodium knowlesi; Duffy negative individuals whose erythrocytes do not express the receptor are resistant to infection. It is a member of the super-family of chemokine receptors and the receptor for the human malarial parasite Plasmodium vivax and the simian malarial parasite Plasmodium knowlesi. The DARC is expressed on erythrocytes and endothelial cells and is required for Plasmodium vivax infection of erythrocytes. www.dadamo.com /wiki/wiki.pl/Duffy_blood_group_system   (1942 words)

MALARIA PUBLICATIONS Phagocytic functions of monocytes in chloroquine.of rhesus monkeys during Plasmodium knowlesi infection and the effect of treatment with chloroquine. Plasmodium Falciparum and blood monocyte induced abnormalities in human erythrocyte cation homeostasis. Plasmodium falciparum: Role of activated blood monocytes in erythrocyte membrane damage and red cell loss during malaria. icmr.nic.in /malaria1.htm   (1344 words)

Pfam 21.0 : Duffy_binding   (Site not responding. Last check: 2007-11-04) Plasmodium vivax and Plasmodium knowlesi merozoites invade human erythrocytes that express Duffy blood group surface determinants. Plasmodium vivax and Plasmodium knowlesi merozoites invade Homo sapiens erythrocytes that express Duffy blood group surface determinants. The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites. pfam.wustl.edu /cgi-bin/getdesc?name=Duffy_binding   (142 words)

G Nigel Godson Ph.D., D.Sc. "Immunogenicity of the repetitive and nonrepetitive peptide regions of the divergent CS protein of Plasmodium knowlesi". Schlesinger DH; Cochrane AH; Gwadz RW; Godson GN; Melton R; Nussenzweig RS; Nussenzweig V. "Structure of an immunodominant epitope of the circumsporozoite surface protein of Plasmodium knowlesi". "Cloning and expression in E. coli of the malarial sporozoite surface antigen gene from Plasmodium knowlesi". www.med.nyu.edu /pubs/godsog01.html   (1644 words)

Characterization of Simian Malarial Parasite (Plasmodium knowlesi)-induced Putrescine Transport in Rhesus Monkey ... of Plasmodium knowlesi (a simian malarial parasite) in rhesus The multidrug-resistant Plasmodium yoelii nigeriensis strain maintained in Swiss mice was used to evaluate the in vivo antimalarial on putrescine influx in Plasmodium knowlesi infected erythrocytes www.jbc.org /cgi/content/full/272/21/13506   (4062 words)

JPMA :::   (Site not responding. Last check: 2007-11-04) The study, published by Nature, focused on Plasmodium knowlesi, a strain of malaria that usually infects monkeys rather than people.1 However, these findings could help in the development of new drugs against Plasmodium vivax that infects 80 million people each year and attacks RBCs in the same way as P. knowlesi. This study characterized conserved patterns of interaction between the protein network of Plasmodium falciparum and those of other species, and reported the specific network regions that are conserved. Some of the observed differences are almost certainly due to incomplete coverage in one or more networks: for instance, the present Plasmodium interaction set is focused on asexual life-cycle stages. jpma.org.pk /jpma/4apr06/fulltex15.htm   (1787 words)

Medical Dictionary: Plasmodium knowlesi - WrongDiagnosis.com Plasmodium knowlesi: A protozoan parasite from Southeast Asia that causes monkey malaria. Plasmodium knowlesi : protozoan parasite from Southeast Asia that causes monkey malaria; naturally acquired by man in Malaysia and can also be transmitted experimentally to humans. The term Plasmodium knowlesi can be used for: www.wrongdiagnosis.com /medical/plasmodium_knowlesi.htm   (217 words)

Transfection of the Primate Malaria Parasite Plasmodium knowlesi Using Entirely Heterologous Constructs -- Wel et al. ... Transfection of the Primate Malaria Parasite Plasmodium knowlesi Using Entirely Heterologous Constructs -- Wel et al. of Plasmodium knowlesi (a primate malaria parasite that clusters Kocken, C. wara, H., van der Wel, A., Beetsma, A. L., Mwenda, J. M., Thomas, A. Plasmodium knowlesi Provides a Rapid In Vitro and In Vivo Transfection System That Enables Double-Crossover Gene Knockout Studies. www.jem.org /cgi/content/abstract/185/8/1499   (435 words)

BioMed Central | Full text | The MB2gene family of Plasmodiumspecies has a unique combination of S1 and GTP-binding ... However, in spite of more than a century of malaria research, much is still unknown about the biology of Plasmodium parasites due in large part to the extraordinary complexity of their life cycles. These parasites are able to infect vertebrate and invertebrate hosts, survive in intracellular and extracellular environments, invade multiple types of cells, and evade the immune responses of both hosts. Alignment of MB2 conceptual translation products from the six Plasmodium species reveals a conservation of overall structure that in the absence of other similar genes allows us to conclude that these are orthologous members of a gene family. www.biomedcentral.com /1471-2105/5/83   (4936 words)

Try your search on: Qwika (all wikis)

About us   |   Why use us?   |   Reviews   |   Press   |   Contact us   Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.